All Stories

  1. Vulnerability of Purkinje Cells Generated from Spinocerebellar Ataxia Type 6 Patient-Derived iPSCs

    Article • Cell Reports, January 2017, Elsevier

    Hideshi Kawakami

  2. Second derivative of the finger photoplethysmogram and cardiovascular mortality in middle-aged and elderly Japanese women

    Article • Hypertension Research, September 2016, Nature

    Hideshi Kawakami

  3. Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis

    Article • Nature Communications, August 2016, Nature

    Hideshi Kawakami

  4. Self-Organization of Polarized Cerebellar Tissue in 3D Culture of Human Pluripotent Stem Cells

    Article • Cell Reports, February 2015, Elsevier

    Hideshi Kawakami

  5. A Japanese patient with familial ALS and a p.K510M mutation in the gene for FUS (FUS) resulting in the totally locked-in state

    Article • Neuropathology, May 2014, Wiley

    Professor Kazuhiko Watabe, Hideshi Kawakami

  6. Exome sequencing reveals a novel TTC19 mutation in an autosomal recessive spinocerebellar ataxia patient

    Article • BMC Neurology, January 2014, Springer Science + Business Media

    Hideshi Kawakami

  7. DYT6 in Japan-genetic screening and clinical characteristics of the patients

    Article • Movement Disorders, November 2013, Wiley

    Hideshi Kawakami

  8. Optineurin suppression causes neuronal cell death via NF‐κB pathway

    Article • Journal of Neurochemistry, June 2013, Wiley

    Hideshi Kawakami

  9. An autopsy case of sporadic amyotrophic lateral sclerosis associated with the I113T SOD1mutation

    Article • Neuropathology, June 2013, Wiley

    Hideshi Kawakami, Masataka Nakamura

  10. Oromandibular dystonia associated with SCA36

    Article • Movement Disorders, February 2013, Wiley

    Hideshi Kawakami

  11. Optineurin and amyotrophic lateral sclerosis

    Article • Geriatrics and Gerontology International, December 2012, Wiley

    Hideshi Kawakami

  12. The clinical characteristics of spinocerebellar ataxia 36: A study of 2121 Japanese ataxia patients

    Article • Movement Disorders, July 2012, Wiley

    Hideshi Kawakami

  13. Severe brain atrophy after long-term survival seen in siblings with familial amyotrophic lateral sclerosis and a mutation in the optineurin gene: a case series

    Article • Journal of Medical Case Reports, December 2011, Springer Science + Business Media

    Hideshi Kawakami

  14. Optineurin with amyotrophic lateral sclerosis-related mutations abrogates inhibition of interferon regulatory factor-3 activation

    Article • Neuroscience Letters, November 2011, Elsevier

    Dr Takemasa Sakaguchi, Hideshi Kawakami

  15. Screening for OPTN mutations in amyotrophic lateral sclerosis in a mainly Caucasian population

    Article • Neurobiology of Aging, October 2011, Elsevier

    Hideshi Kawakami

  16. Homozygosity Mapping on Homozygosity Haplotype Analysis to Detect Recessive Disease-Causing Genes from a Small Number of Unrelated, Outbred Patients

    Article • PLoS ONE, September 2011, PLOS

    Hideshi Kawakami

  17. The UCHL1 S18Y polymorphism and Parkinson’s disease in a Japanese population

    Article • Parkinsonism & Related Disorders, July 2011, Elsevier

    Hideshi Kawakami

  18. Clinicopathologic study on an ALS family with a heterozygous E478G optineurin mutation

    Article • Acta Neuropathologica, June 2011, Springer Science + Business Media

    Dr Masafumi Ihara, Hideshi Kawakami, Masataka Nakamura

  19. Analysis on the Susceptibility Genes in Two Chinese Pedigrees with Familial Parkinson's Disease

    Article • Neurology Research International, January 2010, Hindawi Publishing Corporation

    Hideshi Kawakami

  20. Screening for TARDBP mutations in Japanese familial amyotrophic lateral sclerosis

    Article • Journal of the Neurological Sciences, September 2009, Elsevier

    Hideshi Kawakami

  21. LRRK2mutations and risk variants in Japanese patients with Parkinson's disease

    Article • Movement Disorders, April 2009, Wiley

    Hideshi Kawakami

  22. Aortic Pulse Wave Velocity Predicts Cardiovascular Mortality in Middle-Aged and Elderly Japanese Men

    Article • Circulation Journal, January 2009, Japanese Circulation Society

    Hideshi Kawakami

  23. The CNTN4 c.4256C>T mutation is rare in Japanese with inherited spinocerebellar ataxia

    Article • Journal of the Neurological Sciences, March 2008, Elsevier

    Hideshi Kawakami

  24. Pathogenic expansions of the SCA6 locus are associated with a common CACNA1A haplotype across the globe: founder effect or predisposing chromosome?

    Article • European Journal of Human Genetics, February 2008, Nature

    Hideshi Kawakami, Prof Maria Luiza Saraiva-Pereira

  25. Voltage-gated potassium channel antibodies associated limbic encephalitis in a patient with invasive thymoma

    Article • Journal of the Neurological Sciences, December 2006, Elsevier

    Hideshi Kawakami

  26. NO ASSOCIATION OF COMPLEMENT FACTOR H GENE POLYMORPHISM AND AGE-RELATED MACULAR DEGENERATION IN THE JAPANESE POPULATION

    Article • Retina, November 2006, Wolters Kluwer Health

    Hideshi Kawakami

  27. High frequency of open-angle glaucoma in Japanese patients with Alzheimer's disease

    Article • Journal of the Neurological Sciences, July 2006, Elsevier

    Hideshi Kawakami

  28. Identification of a new family of spinocerebellar ataxia type 14 in the japanese spinocerebellar ataxia population by the screening of PRKCG exon 4

    Article • Movement Disorders, January 2006, Wiley

    Hideshi Kawakami

  29. Influence of a tumor necrosis factor gene polymorphism in Japanese patients with multiple system atrophy

    Article • Neuroscience Letters, February 2005, Elsevier

    Hideshi Kawakami

  30. Activation of human SII cortex during exploratory finger movement and hand clenching tasks

    Article • Neuroreport, February 2005, Wolters Kluwer Health

    Hideshi Kawakami

  31. Glutathione-S-transferase-1 and interleukin-1β gene polymorphisms in Japanese patients with Parkinson's disease

    Article • Movement Disorders, January 2005, Wiley

    Hideshi Kawakami

  32. Brain-derived neurotrophic factor gene polymorphisms in Japanese patients with sporadic Alzheimer's disease, Parkinson's disease, and multiple system atrophy

    Article • Movement Disorders, January 2005, Wiley

    Hideshi Kawakami

  33. Influence of polymorphisms in the genes for cytokines and glutathione S-transferase omega on sporadic Alzheimer’s disease

    Article • Neuroscience Letters, September 2004, Elsevier

    Hideshi Kawakami

  34. Disinhibition of the somatosensory cortex in cervical dystonia—decreased amplitudes of high-frequency oscillations

    Article • Clinical Neurophysiology, July 2004, Elsevier

    Hideshi Kawakami

  35. Quantitative Assessment of Cerebral Blood Flow in Genetically Confirmed Spinocerebellar Ataxia Type 6

    Article • Archives of Neurology, June 2004, American Medical Association (AMA)

    Hideshi Kawakami

  36. A novel haplotype of spinocerebellar ataxia type 6 contributes to the highest prevalence in Western Japan

    Article • Neuroscience Letters, March 2004, Elsevier

    Hideshi Kawakami

  37. Possible Reduced Penetrance of Expansion of 44 to 47 CAG/CAA Repeats in the TATA-Binding Protein Gene in Spinocerebellar Ataxia Type 17

    Article • Archives of Neurology, February 2004, American Medical Association (AMA)

    Hideshi Kawakami

  38. Influence of monocyte chemoattractant protein 1 gene polymorphism on age at onset of sporadic Parkinson's disease

    Article • Movement Disorders, July 2003, Wiley

    Hideshi Kawakami

  39. Contribution of the interleukin-1? gene polymorphism in multiple system atrophy

    Article • Movement Disorders, July 2002, Wiley

    Hideshi Kawakami

  40. Dinucleotide repeat polymorphisms in the Neprilysin gene are not associated with sporadic Alzheimer's disease

    Article • Neuroscience Letters, March 2002, Elsevier

    Hideshi Kawakami

  41. Dopamine Transporter and Parkinson’s Disease

    Article • January 2002, Springer Science + Business Media

    Hideshi Kawakami

  42. Influence of interleukin-1β gene polymorphism on age-at-onset of spinocerebellar ataxia 6 (SCA6) in Japanese patients

    Article • Neuroscience Letters, July 2001, Elsevier

    Hideshi Kawakami

  43. Nicotinic acetylcholine receptors and neurodegenerative disease

    Article • Alcohol, June 2001, Elsevier

    Hideshi Kawakami

  44. Genetic studies in Parkinson's disease with an α-synuclein/NACP gene polymorphism in Japan

    Article • Neuroscience Letters, March 2001, Elsevier

    Hideshi Kawakami

  45. Risk factors for dementia

    Article • January 2001, Springer Science + Business Media

    Hideshi Kawakami

  46. Tumor necrosis factor, tumor necrosis factor receptors type 1 and 2, lymphotoxin-α, and HLA-DRB1 gene polymorphisms in human T-Cell lymphotropic virus type I associated myelopathy

    Article • Human Immunology, December 2000, Elsevier

    Hideshi Kawakami, Professor Masao Matsuoka

  47. Electrophysiological studies in spinocerebellar ataxia type 6

    Article • Neuroreport, April 2000, Wolters Kluwer Health

    Hideshi Kawakami

  48. A single nucleotide polymorphism of dopamine transporter gene is associated with Parkinson's disease

    Article • Annals of Neurology, April 2000, Wiley

    Hideshi Kawakami

  49. Effects of nerve growth factor and nicotine on the expression of nicotinic acetylcholine receptor subunits in PC12 cells

    Article • Neuroscience Research, December 1999, Elsevier

    Hideshi Kawakami

  50. Structure and regulation of the human NeuroD (BETA2/BHF1) gene

    Article • Molecular Brain Research, June 1999, Elsevier

    Hideshi Kawakami

  51. Variation in the number of CAG repeats in the Machado–Joseph disease gene (MJD1) in the Japanese population

    Article • Journal of the Neurological Sciences, June 1999, Elsevier

    Hideshi Kawakami

  52. Identification and analysis of the promoter region of the human NeuroD-related factor (NDRF)

    Article • Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, April 1999, Elsevier

    Hideshi Kawakami

  53. Apolipoprotein E promoter polymorphism and sporadic Alzheimer's disease in a Japanese population

    Article • Neuroscience Letters, January 1999, Elsevier

    Hideshi Kawakami

  54. HLA-DRB1 and tumor necrosis factor gene polymorphisms in Japanese patients with multiple sclerosis

    Article • Journal of Neuroimmunology, December 1998, Elsevier

    Hideshi Kawakami

  55. Characteristic Magnetic Resonance Imaging Findings in Spinocerebellar Ataxia 6

    Article • Archives of Neurology, October 1998, American Medical Association (AMA)

    Hideshi Kawakami

  56. No association between apolipoprotein E alleles and olivopontocerebellar atrophy

    Article • Journal of the Neurological Sciences, June 1998, Elsevier

    Hideshi Kawakami

  57. Effect of amino acid ergot alkaloids on glutamate transport via human glutamate transporter hGluT-1

    Article • Journal of the Neurological Sciences, February 1998, Elsevier

    Hideshi Kawakami

  58. Neurological diseases and dopamine transporter (DAT) and glutamate transporter (GT)

    Article • Neuroscience Research, January 1998, Elsevier

    Hideshi Kawakami

  59. Structure and organization of the gene encoding human dopamine transporter

    Article • Gene, August 1997, Elsevier

    Hideshi Kawakami

  60. Cytokines and myelin antibodies in Crow‐Fukase syndrome

    Article • Muscle & Nerve, December 1996, Wiley

    Hideshi Kawakami

  61. Cytokines and myelin antibodies in Crow-Fukase syndrome

    Article • Muscle & Nerve, December 1996, Wiley

    Hideshi Kawakami

  62. Serum deprivation alters the expression and the splicing at exons 7, 8 and 15 of the β-amyloid precursor protein in the C6 glioma cell line

    Article • Molecular Brain Research, July 1996, Elsevier

    Hideshi Kawakami

  63. Cloning and Expression of a Rat Brain Basic Helix–Loop–Helix Factor

    Article • Biochemical and Biophysical Research Communications, April 1996, Elsevier

    Hideshi Kawakami

  64. Molecular Cloning and Characterization of a cDNA Encoding a Novel Basic Helix-Loop-Helix Protein Structurally Related to NeuroD/BHF1

    Article • Biochemical and Biophysical Research Communications, March 1996, Elsevier

    Hideshi Kawakami

  65. Localization of the gene encoding the human L-glutamate transporter (GLT-1) to 11p11.2–p13 by fluorescence in situ hybridization

    Article • Human Genetics, March 1996, Springer Science + Business Media

    Hideshi Kawakami

  66. Expression of three glutamate transporter subtype mRNAs in human brain regions and peripheral tissues

    Article • Molecular Brain Research, February 1996, Elsevier

    Hideshi Kawakami

  67. Clinical Manifestations of Autosomal Recessive Early-Onset Parkinsonism with Diurnal Fluctuation

    Article • January 1996, Springer Science + Business Media

    Hideshi Kawakami

  68. Neuroprotective mechanism of bromocriptine

    Article • The Lancet, November 1995, Elsevier

    Hideshi Kawakami

  69. WS-18-4 Nicotinic ion channel and neurodegenerative diseases

    Article • Electroencephalography and Clinical Neurophysiology/Electromyography and Motor Control, September 1995, Elsevier

    Hideshi Kawakami

  70. Unique features of the CAG repeats in Machado–Joseph disease

    Article • Nature Genetics, April 1995, Nature

    Hideshi Kawakami

  71. Inhibition by folded isomers of L-2-(carboxycyclopropyl) glycine of glutamate uptake via the human glutamate transporter hGluT-1

    Article • European Journal of Pharmacology Molecular Pharmacology, April 1995, Elsevier

    Hideshi Kawakami

  72. Preoperative localization of brain lesions by magnetic resonance imaging with a marking device

    Article • Journal of Neurosurgery, March 1995, Journal of Neurosurgery Publishing Group (JNSPG)

    Hideshi Kawakami

  73. Effect of Ciliary Neurotrophic Factor on β-Amyloid Precursor Protein mRNA Expression

    Article • January 1995, Springer Science + Business Media

    Hideshi Kawakami

  74. CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1

    Article • Nature Genetics, November 1994, Nature

    Hideshi Kawakami

  75. HLAs and genes in japanese patients with multiple sclerosis: evidence for increased frequencies of HLA-Cw3, HLA-DR2, and HLA-DQB1∗0602

    Article • Human Immunology, October 1992, Elsevier

    Hideshi Kawakami

  76. Structural Organization and Expression of the Gene for Bovine Myosin I Heavy Chain1

    Article • The Journal of Biochemistry, March 1992, Oxford University Press (OUP)

    Hideshi Kawakami