All Stories

  1. Crystallisation of Zika NS5 RdRp v1
  2. Control of phosphodiesterase activity in the regulator of biofilm dispersal RbdA from Pseudomonas aeruginosa
  3. Exploring the sequence-function space of microbial fucosidases
  4. Studies on the selectivity of the SARS-CoV-2 papain-like protease reveal the importance of the P2' proline of the viral polyprotein
  5. Studies on the selectivity of the SARS-CoV-2 papain-like protease reveal the importance of the P2′ proline of the viral polyprotein
  6. The structure of nontypeable Haemophilus influenzae SapA in a closed conformation reveals a constricted ligand-binding cavity and a novel RNA binding motif
  7. Mass spectrometry reveals potential of β-lactams as SARS-CoV-2 Mpro inhibitors
  8. Diamond Light Source: contributions to SARS-CoV-2 biology and therapeutics
  9. Super-Resolution Fluorescence Microscopy Reveals Clustering Behaviour of Chlamydia pneumoniae’s Major Outer Membrane Protein
  10. Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease
  11. An automatic pipeline for the design of irreversible derivatives identifies a potent SARS-CoV-2 Mpro inhibitor
  12. Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease
  13. Fucosidases from the human gut symbiont Ruminococcus gnavus
  14. Differential impact on motility and biofilm dispersal of closely related phosphodiesterases in Pseudomonas aeruginosa
  15. Elucidation of a sialic acid metabolism pathway in mucus-foraging Ruminococcus gnavus unravels mechanisms of bacterial adaptation to the gut
  16. Structural insights into the molecular mechanisms of the Mycobacterium evolvability factor Mfd
  17. Differential impact on motility and biofilm dispersal of closely related phosphodiesterases in Pseudomonas aeruginosa
  18. The structure of Erwinia amylovora AvrRpt2 provides insight into protein maturation and induced resistance to fire blight by Malus × robusta 5
  19. Structural and functional analysis of Erwinia amylovora SrlD. The first crystal structure of a sorbitol-6-phosphate 2-dehydrogenase
  20. A complete structural characterization of the desferrioxamine E biosynthetic pathway from the fire blight pathogen Erwinia amylovora
  21. iNEXT: a European facility network to stimulate translational structural biology
  22. Where is crystallography going?
  23. Interdomain conformational flexibility underpins the activity of UGGT, the eukaryotic glycoprotein secretion checkpoint
  24. Electron Bio-Imaging Centre (eBIC): the UK national research facility for biological electron microscopy
  25. Dimerisation induced formation of the active site and the identification of three metal sites in EAL-phosphodiesterases
  26. Structure of the Streptococcus pneumoniae carbohydrate substrate-binding protein SP0092
  27. Structural Basis for Regulation and Specificity of Fructooligosaccharide Import in Streptococcus pneumoniae
  28. Crystal structure of transketolase from the probiotic bacterium lactobacillus salivarius
  29. Streptococcus pneumoniaeNanC: Structural Insights into the Specificity and Mechanism of a Sialidase that Produces a Sialidase Inhibitor
  30. Ultrafast infrared spectroscopy reveals water-mediated coherent dynamics in an enzyme active site
  31. Application of In Situ Diffraction in High-Throughput Structure Determination Platforms
  32. Targeting Cyclic di-GMP Signalling: A Strategy to Control Biofilm Formation?
  33. SynchLink: an iOS app for ISPyB
  34. Crystal structure of an HD‐GYP domain cyclic‐di‐ GMP phosphodiesterase reveals an enzyme with a novel trinuclear catalytic iron centre
  35. A structural and dynamic investigation of the inhibition of catalase by nitric oxide
  36. Structure of ribose 5-phosphate isomerase from the probiotic bacteriumLactobacillus salivariusUCC118
  37. Measuring protein dynamics with ultrafast two-dimensional infrared spectroscopy
  38. ISPyB: an information management system for synchrotron macromolecular crystallography
  39. Structural Basis for Streptococcus pneumoniae NanA Inhibition by Influenza Antivirals Zanamivir and Oseltamivir Carboxylate
  40. Structural Basis of the Sensor-Synthase Interaction in Autoinduction of the Quorum Sensing Signal DSF Biosynthesis
  41. MxCuBE: a synchrotron beamline control environment customized for macromolecular crystallography experiments
  42. Structural basis of YAP recognition by TEAD4 in the Hippo pathway
  43. Allelic Variation of Bile Salt Hydrolase Genes in Lactobacillus salivarius Does Not Determine Bile Resistance Levels
  44. Structural basis for translational inhibition by the tumour suppressor Pdcd4
  45. Unusual Chromophore and Cross-Links in Ranasmurfin: A Blue Protein from the Foam Nests of a Tropical Frog
  46. Unusual Chromophore and Cross-Links in Ranasmurfin: A Blue Protein from the Foam Nests of a Tropical Frog
  47. Structural and functional studies of Streptococcus pneumoniae neuraminidase B: An intramolecular trans -sialidase
  48. Crystal Structure of Human Edc3 and Its Functional Implications
  49. Crystal Structure of Human Kynurenine Aminotransferase II, a Drug Target for the Treatment of Schizophrenia
  50. Structure of the equine arteritis virus nucleocapsid protein reveals a dimer–dimer arrangement
  51. Crystallization of Ranasmurfin, a blue-coloured protein fromPolypedates leucomystax
  52. Automation of sample mounting for macromolecular crystallography
  53. The Structural Biology Center 19ID undulator beamline: facility specifications and protein crystallographic results
  54. Overcoming the false-minima problem in direct methods: structure determination of the packaging enzyme P4 from bacteriophage ϕ13
  55. Crystal Structures of Human DcpS in Ligand-free and m7GDP-bound forms Suggest a Dynamic Mechanism for Scavenger mRNA Decapping
  56. Going soft and SAD with manganese
  57. Crystallization and preliminary X-ray diffraction analysis of bacteriophage ϕ12 packaging factor P7
  58. West Nile Virus Core Protein
  59. Crystal Structure and Functional Analysis of the Eukaryotic Class II Release Factor eRF3 from S. pombe
  60. A Novel ADP- and Zinc-binding fold from function-directed in vitro evolution
  61. A novel ADP- and zinc-binding fold from function-directed in vitro evolution
  62. The nsp9 Replicase Protein of SARS-Coronavirus, Structure and Functional Insights
  63. The nsp9 Replicase Protein of SARS-Coronavirus, Structure and Functional Insights
  64. Crystal Structure of a Human VH:  Requirements for Maintaining a Monomeric Fragment † , ‡
  65. Structural Studies on Flavin Reductase PheA2 Reveal Binding of NAD in an Unusual Folded Conformation and Support Novel Mechanism of Action
  66. Soft-SAD crystal structure of a pheromone binding protein from the honeybee Apis mellifera L.
  67. Sulfur Single-wavelength Anomalous Diffraction Crystal Structure of a Pheromone-Binding Protein from the HoneybeeApis melliferaL
  68. Expression, purification, crystallization and preliminary crystallographic analysis of the calponin-homology domain of Rng2
  69. Crystal structure of MboIIA methyltransferase
  70. The 2-A Crystal Structure of 6-Oxo Camphor Hydrolase: NEW STRUCTURAL DIVERSITY IN THE CROTONASE SUPERFAMILY
  71. Crystallographic Investigation of the Role of Aspartate 95 in the Modulation of the Redox Potentials of Desulfovibrio vulgaris Flavodoxin † , ‡
  72. Crystal structures of penicillin acylase enzyme-substrate complexes: structural insights into the catalytic mechanism 1 1Edited by K. Nagai
  73. A thermophilic mini-chaperonin contains a conserved polypeptide-binding surface: combined crystallographic and NMR studies of the GroEL apical domain with implications for substrate interactions11Edited by A. R. Fersht
  74. Inhibition of the Hepatitis C Virus NS3/4A Protease. The Crystal Structures of Two Protease-Inhibitor Complexes (inhibitor II)
  75. Inhibition of the Hepatitis C Virus NS3/4A Protease. The Crystal Structures of Two Protease-Inhibitor Complexes (apo structure)
  76. Structure of RsrI methyltransferase, a member of the N6-adenine beta class of DNA methyltransferases
  77. Structure of cyanase reveals that a novel dimeric and decameric arrangement of subunits is required for formation of the enzyme active site
  78. Inhibition of the Hepatitis C Virus NS3/4A Protease: THE CRYSTAL STRUCTURES OF TWO PROTEASE-INHIBITOR COMPLEXES
  79. Crystal structure of δ-chymotrypsin bound to a peptidyl chloromethyl ketone inhibitor
  80. MAD data collection – current trends
  81. Taking MAD to the extreme: ultrafast protein structure determination
  82. Structure of a new crystal form of human Hsp70 ATPase domain
  83. Crystallization and preliminary crystallographic analysis of an NADH oxidase that functions in peroxide reduction inThermus aquaticusYT-1
  84. X-ray crystal structure of the Desulfovibrio vulgaris (Hildenborough) apoflavodoxin-riboflavin complex
  85. Refinement of Triclinic Hen Egg-White Lysozyme at Atomic Resolution
  86. Modulation of the Redox Potentials of FMN in Desulfovibrio v ulgaris Flavodoxin:  Thermodynamic Properties and Crystal Structures of Glycine-61 Mutants † , ‡
  87. Crystallization and preliminary X-ray crystallographic analysis of the electron-transferring flavoprotein fromMegasphaera elsdenii