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  1. <em>Chlamydia trachomatis</em> ompA Genotype and Clinical Signs of Trachoma in a Longitudinal Tanzanian Cohort

    Article • January 2026, MDPI AG

    Dr Martin Holland

  2. Comparative transcriptomic profiling of human conjunctival epithelial cells and macrophages in response to Chlamydia trachomatis genovars A and B in early- and mid-infection cycles

    Article • November 2025, Cold Spring Harbor Laboratory Press

    Dr Martin Holland

  3. Evolutionary dynamics in the genome of ocular Chlamydia trachomatis strains from Northern Tanzania following mass drug administration

    Article • Microbial Genomics, July 2025, Society for General Microbiology

    Dr Martin Holland

  4. Multimodal mucosal and systemic immune characterization of a non-human primate trachoma model highlights the critical role of local immunity during acute phase disease

    Article • PLoS Neglected Tropical Diseases, August 2024, PLOS

    Dr Martin Holland

  5. Genomic profiling and characterization of ocular Chlamydia trachomatis reference strain B/HAR36

    Article • Microbiology Resource Announcements, June 2024, ASM Journals

    Dr Martin Holland

  6. Evolutionary Dynamics in the Genome of Ocular Chlamydia trachomatis Strains from Northern Tanzania, pre- and post- Mass Drug Administration

    Article • May 2024, Springer Science + Business Media

    Dr Martin Holland

  7. Evolutionary Dynamics in the Genome of Ocular Chlamydia trachomatis Strains from Northern Tanzania, pre- and post- Mass Drug Administration

    Article • May 2024, Springer Science + Business Media

    Dr Martin Holland

  8. Unravelling Chlamydia trachomatis diversity in Amhara, Ethiopia: MLVA-ompA sequencing as a molecular typing tool for trachoma

    Article • PLoS Neglected Tropical Diseases, April 2024, PLOS

    Dr Martin Holland

  9. Genomic insights into local-scale evolution of ocular Chlamydia trachomatis strains within and between individuals in Gambian trachoma-endemic villages

    Article • Microbial Genomics, March 2024, Society for General Microbiology

    Dr Martin Holland

  10. Genomic insights into local scale evolution of ocularChlamydia trachomatisstrains within and between individuals in Gambian trachoma-endemic villages

    Article • December 2023, Cold Spring Harbor Laboratory Press

    Dr Martin Holland

  11. Multimodal mucosal and systemic immune characterization of a novel non-human primate trachoma model highlights the critical role of local immunity during acute phase disease

    Article • December 2023, Cold Spring Harbor Laboratory Press

    Dr Martin Holland

  12. Longitudinal changes in tear cytokines and antimicrobial proteins in trachomatous disease

    Article • PLoS Neglected Tropical Diseases, October 2023, PLOS

    Dr Martin Holland

  13. When Bacteria and Viruses Collide: A Tale of Chlamydia trachomatis and Sexually Transmitted Viruses

    Article • Viruses, September 2023, MDPI AG

    Dr Martin Holland

  14. Prevalence of five treatable sexually transmitted infections among women in Lower River region of The Gambia

    Article • BMC Infectious Diseases, July 2023, Springer Science + Business Media

    Dr Martin Holland

  15. A systems serology approach to the investigation of infection-induced antibody responses and protection in trachoma

    Article • Frontiers in Immunology, May 2023, Frontiers

    Dr Martin Holland

  16. A Systems Serology Approach to the Investigation of Infection-Induced Antibody Responses and Protection in Trachoma

    Article • March 2023, Cold Spring Harbor Laboratory Press

    Dr Martin Holland

  17. Longitudinal Changes in Tear Cytokines and Antimicrobial Proteins in Trachomatous Disease

    Article • February 2023, Research Square

    Dr Martin Holland

  18. Sequence based HLA-DRB1, -DQB1 and -DPB1 allele and haplotype frequencies in The Gambia

    Article • Human Immunology, February 2023, Elsevier

    Dr Martin Holland

  19. HLA-A, -B, -C, -DPB1, -DQB1 and -DRB1 allele frequencies of North Tanzanian Maasai

    Article • Human Immunology, February 2023, Elsevier

    Dr Martin Holland

  20. The conjunctival transcriptome in Ethiopians after trichiasis surgery: associations with the development of eyelid contour abnormalities and the effect of oral doxycycline treatment

    Article • Wellcome Open Research, November 2022, Faculty of 1000, Ltd.

    Dr Martin Holland

  21. Editorial: Next-generation sequencing in ophthalmology: The microbiome in ocular health and disease

    Article • Frontiers in Cellular and Infection Microbiology, November 2022, Frontiers

    Dr Martin Holland

  22. Prevalence of five curable sexually transmitted infections among women in Lower River Region of The Gambia

    Article • November 2022, Research Square

    Dr Martin Holland

  23. The conjunctival microbiome before and after azithromycin mass drug administration for trachoma control in a cohort of Tanzanian children

    Article • Frontiers in Public Health, October 2022, Frontiers

    Dr Martin Holland

  24. Publisher Correction: A Chlamydia trachomatis VD1-MOMP vaccine elicits cross-neutralizing and protective antibodies against C/C-related complex serovars

    Article • npj Vaccines, August 2022, Springer Science + Business Media

    Dr Martin Holland

  25. Deconvolution of Bulk Transcriptomics Data Suggests Changes in Conjunctival Immune Cell Populations in Trachoma

    Article • August 2022, Research Square

    Dr Martin Holland

  26. Association between intestinal bacterial carriage, biomarkers of environmental enteric dysfunction, and stunting in rural Malawian children

    Article • Gates Open Research, July 2022, Faculty of 1000, Ltd.

    Dr Martin Holland

  27. Biannual Administrations of Azithromycin and the Gastrointestinal Microbiome of Malawian Children: A Nested Cohort Study Within a Randomized Controlled Trial

    Article • Frontiers in Public Health, February 2022, Frontiers

    Dr Martin Holland

  28. Impact of azithromycin mass drug administration on the antibiotic-resistant gut microbiome in children: a randomized, controlled trial

    Article • Gut Pathogens, January 2022, Springer Science + Business Media

    Dr Martin Holland

  29. Fecal biomarkers of environmental enteric dysfunction and the gut microbiota of rural Malawian children: An observational study

    Article • Heliyon, October 2021, Elsevier

    Dr Martin Holland

  30. Mass drug administration with azithromycin for trachoma elimination and the population structure of Streptococcus pneumoniae in the nasopharynx

    Article • Clinical Microbiology and Infection, June 2021, Elsevier

    Dr Martin Holland

  31. A Chlamydia trachomatis VD1-MOMP vaccine elicits cross-neutralizing and protective antibodies against C/C-related complex serovars

    Article • npj Vaccines, April 2021, Springer Science + Business Media

    Dr Martin Holland

  32. Fecal biomarkers of environmental enteric dysfunction and the gut microbiota of rural Malawian children: an observational study

    Article • January 2021, Cold Spring Harbor Laboratory Press

    Dr Martin Holland

  33. Facial cleanliness indicators by time of day: results of a cross-sectional trachoma prevalence survey in Senegal

    Article • Parasites & Vectors, November 2020, Springer Science + Business Media

    Dr Martin Holland

  34. DjinniChip: evaluation of a novel molecular rapid diagnostic device for the detection of Chlamydia trachomatis in trachoma-endemic areas

    Article • Parasites & Vectors, October 2020, Springer Science + Business Media

    Dr Martin Holland

  35. Genomics of Ocular Chlamydia trachomatis After 5 Years of SAFE Interventions for Trachoma in Amhara, Ethiopia

    Article • The Journal of Infectious Diseases, October 2020, Oxford University Press (OUP)

    Dr Martin Holland

  36. Up to Four Biannual Administrations of Mass Azithromycin Treatment Are Associated with Modest Changes in the Gut Microbiota of Rural Malawian Children

    Article • October 2020, MDPI AG

    Dr Martin Holland

  37. Viability PCR shows that non-ocular surfaces could contribute to transmission of Chlamydia trachomatis infection in trachoma

    Article • PLoS Neglected Tropical Diseases, July 2020, PLOS

    Oumer Shafi Abdurahman, Dr Martin Holland

  38. Mass drug administration with azithromycin for trachoma elimination and the population structure of Streptococcus pneumoniae in the nasopharynx

    Article • April 2020, Cold Spring Harbor Laboratory Press

    Dr Martin Holland

  39. Immunopathogenesis of Progressive Scarring Trachoma: Results of a 4-Year Longitudinal Study in Tanzanian Children

    Article • Infection and Immunity, March 2020, ASM Journals

    Dr Martin Holland

  40. Whole-genome sequencing of ocular Chlamydia trachomatis isolates from Gadarif State, Sudan

    Article • Parasites & Vectors, November 2019, Springer Science + Business Media

    Dr Martin Holland

  41. Impact of a single round of mass drug administration with azithromycin on active trachoma and ocular Chlamydia trachomatis prevalence and circulating strains in The Gambia and Senegal

    Article • Parasites & Vectors, October 2019, Springer Science + Business Media

    Dr Martin Holland

  42. The conjunctival transcriptome in Ethiopians after trichiasis surgery: associations with the development of eyelid contour abnormalities and the effect of oral doxycycline treatment

    Article • Wellcome Open Research, September 2019, Faculty of 1000, Ltd.

    Dr Martin Holland

  43. Conjunctival Microbiome-Host Responses Are Associated With Impaired Epithelial Cell Health in Both Early and Late Stages of Trachoma

    Article • Frontiers in Cellular and Infection Microbiology, August 2019, Frontiers

    Dr Martin Holland

  44. Influenza Vaccination Primes Human Myeloid Cell Cytokine Secretion and NK Cell Function

    Article • The Journal of Immunology, August 2019, The American Association of Immunologists

    Dr Martin Holland

  45. Progression of scarring trachoma in Tanzanian children: A four-year cohort study

    Article • PLoS Neglected Tropical Diseases, August 2019, PLOS

    Dr Martin Holland

  46. Ocular immune responses, Chlamydia trachomatis infection and clinical signs of trachoma before and after azithromycin mass drug administration in a treatment naïve trachoma-endemic Tanzanian community

    Article • PLoS Neglected Tropical Diseases, July 2019, PLOS

    Dr Martin Holland

  47. Pathway-Wide Genetic Risks in Chlamydial Infections Overlap between Tissue Tropisms: A Genome-Wide Association Scan

    Article • Mediators of Inflammation, June 2018, Hindawi Publishing Corporation

    Dr Martin Holland

  48. Is Trachoma disease severity linked to ocular Chlamydia trachomatis pathogen strain variation

    Article • Genome Medicine, February 2018, Springer Science + Business Media

    Dr Martin Holland

  49. Conjunctival transcriptome profiling of Solomon Islanders with active trachoma in the absence of Chlamydia trachomatis infection

    Article • Parasites & Vectors, February 2018, Springer Science + Business Media

    Dr Martin Holland

  50. Evaluation of a Chlamydia trachomatis-specific, commercial, real-time PCR for use with ocular swabs

    Article • Parasites & Vectors, February 2018, Springer Science + Business Media

    Dr Martin Holland

  51. Active Trachoma Cases in the Solomon Islands Have Varied Polymicrobial Community Structures but Do Not Associate with Individual Non-Chlamydial Pathogens of the Eye

    Article • Frontiers in Medicine, January 2018, Frontiers

    Dr Martin Holland

  52. An outbreak of acute haemorrhagic conjunctivitis associated with coxsackievirus A24 variant in The Gambia, West Africa

    Article • BMC Research Notes, December 2017, Springer Science + Business Media

    Dr Martin Holland

  53. The impact of a single round of community mass treatment with azithromycin on disease severity and ocular Chlamydia trachomatis load in treatment-naïve trachoma-endemic island communities in West Africa

    Article • Parasites & Vectors, December 2017, Springer Science + Business Media

    Dr Martin Holland

  54. Pathways-wide genetic risks in Chlamydial infections overlap between tissue tropisms: A genome-wide association scan

    Article • October 2017, Cold Spring Harbor Laboratory Press

    Dr Martin Holland

  55. Population-based analysis of ocularChlamydia trachomatisin trachoma-endemic West African communities identifies genomic markers of disease severity

    Article • October 2017, Cold Spring Harbor Laboratory Press

    Dr Martin Holland

  56. Immunofibrogenic Gene Expression Patterns in Tanzanian Children with Ocular Chlamydia trachomatis Infection, Active Trachoma and Scarring: Baseline Results of a 4-Year Longitudinal Study

    Article • Frontiers in Cellular and Infection Microbiology, September 2017, Frontiers

    Dr Martin Holland

  57. Genome-wide profiling of humoral immunity and pathogen genes under selection identifies immune evasion tactics of Chlamydia trachomatis during ocular infection

    Article • Scientific Reports, August 2017, Springer Science + Business Media

    Dr Martin Holland

  58. Reduced-cost Chlamydia trachomatis -specific multiplex real-time PCR diagnostic assay evaluated for ocular swabs and use by trachoma research programmes

    Article • Journal of Microbiological Methods, August 2017, Elsevier

    Dr Martin Holland

  59. Population-based prevalence survey of follicular trachoma and trachomatous trichiasis in the Casamance region of Senegal

    Article • BMC Public Health, July 2017, Springer Science + Business Media

    Dr Martin Holland

  60. Persistence of Innate Immune Pathways in Late Stage Human Bacterial and Fungal Keratitis: Results from a Comparative Transcriptome Analysis

    Article • Frontiers in Cellular and Infection Microbiology, May 2017, Frontiers

    Dr Martin Holland

  61. Spatial clustering of high load ocular Chlamydia trachomatis infection in trachoma: a cross-sectional population-based study

    Article • Pathogens and Disease, May 2017, Oxford University Press (OUP)

    Dr Martin Holland

  62. Short-term increase in prevalence of nasopharyngeal carriage of macrolide-resistant Staphylococcus aureus following mass drug administration with azithromycin for trachoma control

    Article • BMC Microbiology, March 2017, Springer Science + Business Media

    Dr Martin Holland

  63. Profiling and validation of individual and patterns of Chlamydia trachomatis-specific antibody responses in trachomatous trichiasis

    Article • Parasites & Vectors, March 2017, Springer Science + Business Media

    Dr Martin Holland

  64. miRNAs that associate with conjunctival inflammation and ocular Chlamydia trachomatis infection do not predict progressive disease

    Article • Pathogens and Disease, February 2017, Oxford University Press (OUP)

    Dr Martin Holland

  65. Defining Seropositivity Thresholds for Use in Trachoma Elimination Studies

    Article • PLoS Neglected Tropical Diseases, January 2017, PLOS

    Dr Martin Holland

  66. The Relationship between Active Trachoma and Ocular Chlamydia trachomatis Infection before and after Mass Antibiotic Treatment

    Article • PLoS Neglected Tropical Diseases, October 2016, PLOS

    Dr Martin Holland

  67. Blinding Trachoma: Systematic Review of Rates and Risk Factors for Progressive Disease

    Article • PLoS Neglected Tropical Diseases, August 2016, PLOS

    Dr Martin Holland

  68. Mycobacterium leprae Activates Toll-Like Receptor-4 Signaling and Expression on Macrophages Depending on Previous Bacillus Calmette-Guerin Vaccination

    Article • Frontiers in Cellular and Infection Microbiology, July 2016, Frontiers

    Dr Martin Holland

  69. Differential frequency of NKG2C/KLRC2 deletion in distinct African populations and susceptibility to Trachoma: a new method for imputation of KLRC2 genotypes from SNP genotyping data

    Article • Human Genetics, June 2016, Springer Science + Business Media

    Dr Martin Holland

  70. Increased Epithelial Expression of CTGF and S100A7 with Elevated Subepithelial Expression of IL-1β in Trachomatous Trichiasis

    Article • PLoS Neglected Tropical Diseases, June 2016, PLOS

    Dr Martin Holland

  71. Immunohistochemical Analysis of Scarring Trachoma Indicates Infiltration by Natural Killer and Undefined CD45 Negative Cells

    Article • PLoS Neglected Tropical Diseases, May 2016, PLOS

    Dr Martin Holland

  72. Ocular chlamydial genomic variants and disease severity in trachoma: a cross-sectional population-based genome-wide association study

    Article • The Lancet, February 2016, Elsevier

    Dr Martin Holland

  73. Can corneal pannus with trachomatous inflammation – follicular be used in combination as an improved specific clinical sign for current ocular Chlamydia trachomatis infection?

    Article • Parasites & Vectors, January 2016, Springer Science + Business Media

    Dr Martin Holland

  74. Inverse relationship between microRNA-155 and -184 expression with increasing conjunctival inflammation during ocular Chlamydia trachomatis infection

    Article • BMC Infectious Diseases, December 2015, Springer Science + Business Media

    Dr Martin Holland

  75. Conjunctival fibrosis and the innate barriers to Chlamydia trachomatis intracellular infection: a genome wide association study

    Article • Scientific Reports, November 2015, Springer Science + Business Media

    Dr Martin Holland

  76. Intramuscular Immunisation with Chlamydial Proteins Induces Chlamydia trachomatis Specific Ocular Antibodies

    Article • PLOS One, October 2015, PLOS

    Dr Martin Holland

  77. Pathogenesis of Progressive Scarring Trachoma in Ethiopia and Tanzania and Its Implications for Disease Control: Two Cohort Studies

    Article • PLoS Neglected Tropical Diseases, May 2015, PLOS

    Dr Martin Holland

  78. Costs of Testing for Ocular Chlamydia trachomatis Infection Compared to Mass Drug Administration for Trachoma in The Gambia: Application of Results from the PRET Study

    Article • PLoS Neglected Tropical Diseases, April 2015, PLOS

    Dr Martin Holland

  79. Serology for Trachoma Surveillance after Cessation of Mass Drug Administration

    Article • PLoS Neglected Tropical Diseases, February 2015, PLOS

    Dr Martin Holland

  80. Trachoma and Ocular Chlamydial Infection in the Era of Genomics

    Article • Mediators of Inflammation, January 2015, Hindawi Publishing Corporation

    Dr Martin Holland

  81. Anthropometric indices of Gambian children after one or three annual rounds of mass drug administration with azithromycin for trachoma control

    Article • BMC Public Health, November 2014, Springer Science + Business Media

    Dr Martin Holland

  82. Whole-genome enrichment and sequencing of Chlamydia trachomatisdirectly from clinical samples

    Article • BMC Infectious Diseases, November 2014, Springer Science + Business Media

    Dr Martin Holland

  83. The conjunctival microbiome in health and trachomatous disease: a case control study

    Article • Genome Medicine, November 2014, Springer Science + Business Media

    Dr Martin Holland

  84. Non-Participation during Azithromycin Mass Treatment for Trachoma in The Gambia: Heterogeneity and Risk Factors

    Article • PLoS Neglected Tropical Diseases, August 2014, PLOS

    Dr Martin Holland

  85. Risk Factors for Active Trachoma and Ocular Chlamydia trachomatis Infection in Treatment-Naïve Trachoma-Hyperendemic Communities of the Bijagós Archipelago, Guinea Bissau

    Article • PLoS Neglected Tropical Diseases, June 2014, PLOS

    Dr Martin Holland

  86. Mass administration of azithromycin and Streptococcus pneumoniae carriage: cross-sectional surveys in the Gambia

    Article • Bulletin of the World Health Organization, April 2014, WHO Press

    Dr Martin Holland

  87. Will droplet digital PCR become the test of choice for detecting and quantifying ocularChlamydia trachomatisinfection? Maybe

    Article • Expert Review of Molecular Diagnostics, March 2014, Taylor & Francis

    Dr Martin Holland

  88. Conjunctival Scarring in Trachoma Is Associated with the HLA-C Ligand of KIR and Is Exacerbated by Heterozygosity at KIR2DL2/KIR2DL3

    Article • PLoS Neglected Tropical Diseases, March 2014, PLOS

    Dr Martin Holland

  89. Towards a safe and effective chlamydial vaccine: Lessons from the eye

    Article • Vaccine, March 2014, Elsevier

    Dr Martin Holland

  90. Effect of azithromycin mass drug administration for trachoma on spleen rates in Gambian children

    Article • Tropical Medicine & International Health, January 2014, Wiley

    Dr Martin Holland

  91. Killer-cell Immunoglobulin-like Receptor gene linkage and copy number variation analysis by droplet digital PCR

    Article • Genome Medicine, January 2014, Springer Science + Business Media

    Dr Martin Holland

  92. Plasmid Copy Number and Disease Severity in Naturally Occurring Ocular Chlamydia trachomatis Infection

    Article • Journal of Clinical Microbiology, November 2013, ASM Journals

    Dr Martin Holland

  93. In vivo confocal microscopy and histopathology of the conjunctiva in trachomatous scarring and normal tissue: a systematic comparison

    Article • British Journal of Ophthalmology, August 2013, BMJ

    Dr Martin Holland

  94. Association between Ocular Bacterial Carriage and Follicular Trachoma Following Mass Azithromycin Distribution in The Gambia

    Article • PLoS Neglected Tropical Diseases, July 2013, PLOS

    Dr Martin Holland

  95. Correction: Mass Treatment with Azithromycin for Trachoma: When Is One Round Enough? Results from the PRET Trial in The Gambia

    Article • PLoS Neglected Tropical Diseases, June 2013, PLOS

    Dr Martin Holland

  96. Mass Treatment with Azithromycin for Trachoma: When Is One Round Enough? Results from the PRET Trial in The Gambia

    Article • PLoS Neglected Tropical Diseases, June 2013, PLOS

    Dr Martin Holland

  97. Development and Evaluation of a Next-Generation Digital PCR Diagnostic Assay for Ocular Chlamydia trachomatis Infections

    Article • Journal of Clinical Microbiology, May 2013, ASM Journals

    Dr Martin Holland

  98. Conjunctival MicroRNA Expression in Inflammatory Trachomatous Scarring

    Article • PLoS Neglected Tropical Diseases, March 2013, PLOS

    Dr Martin Holland

  99. Trachoma: Protective and Pathogenic Ocular Immune Responses to Chlamydia trachomatis

    Article • PLoS Neglected Tropical Diseases, February 2013, PLOS

    Dr Martin Holland

  100. Biogeography of the ecosystems of the healthy human body

    Article • Genome Biology, January 2013, Springer Science + Business Media

    Dr Tatiana A Vishnivetskaya, Dr Martin Holland

  101. Eyescores: an open platform for secure electronic data and photographic evidence collection in ophthalmological field studies

    Article • British Journal of Ophthalmology, December 2012, BMJ

    Dr Martin Holland

  102. Post-Operative Recurrent Trachomatous Trichiasis Is Associated with Increased Conjunctival Expression of S100A7 (Psoriasin)

    Article • PLoS Neglected Tropical Diseases, December 2012, PLOS

    Mr Bayeh Abera Beyene, Dr Martin Holland

  103. A Diagnostics Platform for the Integrated Mapping, Monitoring, and Surveillance of Neglected Tropical Diseases: Rationale and Target Product Profiles

    Article • PLoS Neglected Tropical Diseases, July 2012, PLOS

    Dr Martin Holland

  104. Genome-Wide Identification ofChlamydia trachomatisAntigens Associated with Trachomatous Trichiasis

    Article • Investigative Ophthalmology & Visual Science, May 2012, Association for Research in Vision and Ophthalmology (ARVO)

    Dr Martin Holland

  105. Whole-genome analysis of diverse Chlamydia trachomatis strains identifies phylogenetic relationships masked by current clinical typing

    Article • Nature Genetics, March 2012, Springer Science + Business Media

    Professor Julian Parkhill, Dr Martin Holland

  106. Innate Immune Responses and Modified Extracellular Matrix Regulation Characterize Bacterial Infection and Cellular/Connective Tissue Changes in Scarring Trachoma

    Article • Infection and Immunity, October 2011, ASM Journals

    Dr Martin Holland

  107. Active Trachoma Is Associated with Increased Conjunctival Expression ofIL17Aand Profibrotic Cytokines

    Article • Infection and Immunity, September 2011, ASM Journals

    Dr Martin Holland

  108. Diagnostic Accuracy of a Prototype Point-of-Care Test for Ocular Chlamydia trachomatis under Field Conditions in The Gambia and Senegal

    Article • PLoS Neglected Tropical Diseases, August 2011, PLOS

    Dr Martin Holland

  109. Design and Baseline Data of a Randomized Trial to Evaluate Coverage and Frequency of Mass Treatment with Azithromycin: The Partnership for Rapid Elimination of Trachoma (PRET) in Tanzania and The Gambia

    Article • Ophthalmic Epidemiology, January 2011, Taylor & Francis

    Dr Martin Holland

  110. Systemic effector and regulatory immune responses to chlamydial antigens in trachomatous trichiasis

    Article • Frontiers in Microbiology, January 2011, Frontiers

    Dr Martin Holland

  111. Trachoma Prevalence and Associated Risk Factors in The Gambia and Tanzania: Baseline Results of a Cluster Randomised Controlled Trial

    Article • PLoS Neglected Tropical Diseases, November 2010, PLOS

    Dr Martin Holland

  112. Conjunctival Transcriptome in Scarring Trachoma

    Article • Infection and Immunity, October 2010, ASM Journals

    Dr Martin Holland

  113. Profound and Sustained Reduction in Chlamydia trachomatis in The Gambia: A Five-Year Longitudinal Study of Trachoma Endemic Communities

    Article • PLoS Neglected Tropical Diseases, October 2010, PLOS

    Dr Martin Holland

  114. Trichiasis Surgery in The Gambia: A 4-Year Prospective Study

    Article • Investigative Ophthalmology & Visual Science, October 2010, Association for Research in Vision and Ophthalmology (ARVO)

    Dr Martin Holland

  115. Human Conjunctival Transcriptome Analysis Reveals the Prominence of Innate Defense in Chlamydia trachomatis Infection

    Article • Infection and Immunity, September 2010, ASM Journals

    Dr Martin Holland

  116. Pathway-Focused Arrays Reveal Increased Matrix Metalloproteinase-7 (Matrilysin) Transcription in Trachomatous Trichiasis

    Article • Investigative Ophthalmology & Visual Science, August 2010, Association for Research in Vision and Ophthalmology (ARVO)

    Dr Martin Holland

  117. Phylogenetic Analysis of Chlamydia trachomatis Tarp and Correlation with Clinical Phenotype

    Article • Infection and Immunity, July 2010, ASM Journals

    Dr Martin Holland

  118. Conjunctival Expression of Matrix Metalloproteinase and Proinflammatory Cytokine Genes after Trichiasis Surgery

    Article • Investigative Ophthalmology & Visual Science, July 2010, Association for Research in Vision and Ophthalmology (ARVO)

    Dr Martin Holland

  119. Haptoglobin and Sickle Cell Polymorphisms and Risk of Active Trachoma in Gambian Children

    Article • PLOS One, June 2010, PLOS

    Dr Martin Holland

  120. Active Trachoma and Ocular Chlamydia trachomatis Infection in Two Gambian Regions: On Course for Elimination by 2020?

    Article • PLoS Neglected Tropical Diseases, December 2009, PLOS

    Dr Martin Holland

  121. Innate immunity in ocular Chlamydia trachomatis infection: contribution of IL8 and CSF2 gene variants to risk of trachomatous scarring in Gambians

    Article • BMC Medical Genetics, December 2009, Springer Science + Business Media

    Dr Martin Holland

  122. Dirty hands: bacteria of faecal origin on commuters' hands

    Article • Epidemiology and Infection, September 2009, Cambridge University Press

    Dr Martin Holland

  123. When Can Antibiotic Treatments for Trachoma Be Discontinued? Graduating Communities in Three African Countries

    Article • PLoS Neglected Tropical Diseases, June 2009, PLOS

    Dr Martin Holland

  124. The Development of an Age-Structured Model for Trachoma Transmission Dynamics, Pathogenesis and Control

    Article • PLoS Neglected Tropical Diseases, June 2009, PLOS

    Professor Maria-Gloria Basáñez, Dr Martin Holland

  125. A chlamydial type III-secreted effector protein (Tarp) is predominantly recognized by antibodies from humans infected with Chlamydia trachomatis and induces protective immunity against upper genital tract pathologies in mice

    Article • Vaccine, May 2009, Elsevier

    Dr Martin Holland

  126. Revealing the History of Sheep Domestication Using Retrovirus Integrations

    Article • Science, April 2009, American Association for the Advancement of Science

    Professor Massimo Palmarini, Dr Martin Holland

  127. Estimating Household and Community Transmission of Ocular Chlamydia trachomatis

    Article • PLoS Neglected Tropical Diseases, March 2009, PLOS

    Professor Maria-Gloria Basáñez, Dr Martin Holland

  128. Co-evolution of genomes and plasmids within Chlamydia trachomatis and the emergence in Sweden of a new variant strain

    Article • BMC Genomics, January 2009, Springer Science + Business Media

    Professor Julian Parkhill, Dr Martin Holland

  129. Risk factors for active trachoma in The Gambia

    Article • Transactions of the Royal Society of Tropical Medicine and Hygiene, December 2008, Oxford University Press (OUP)

    Dr Martin Holland

  130. Chlamydia trachomatis ompA Variants in Trachoma: What Do They Tell Us?

    Article • PLoS Neglected Tropical Diseases, September 2008, PLOS

    Dr Martin Holland

  131. Analysis of flow cytometry data using an automatic processing tool

    Article • Cytometry Part A, September 2008, Wiley

    Dr Martin Holland

  132. Two Doses of Azithromycin to Eliminate Trachoma in a Tanzanian Community

    Article • The New England Journal of Medicine and Surgery and the Collateral Branches of Science, April 2008, New England Journal of Medicine (NEJM/MMS)

    Dr Martin Holland

  133. Pathogenic Diversity amongChlamydia trachomatisOcular Strains in Nonhuman Primates Is Affected by Subtle Genomic Variations

    Article • The Journal of Infectious Diseases, February 2008, Oxford University Press (OUP)

    Dr Martin Holland

  134. Susceptibility to sequelae of human ocular chlamydial infection associated with allelic variation in IL10 cis-regulation

    Article • Human Molecular Genetics, October 2007, Oxford University Press (OUP)

    Dr Martin Holland

  135. FOXP3 gene expression in a tuberculosis case contact study

    Article • Clinical & Experimental Immunology, April 2007, Wiley

    Moses Lugos, Dr Martin Holland

  136. Genetic variation at the TNF locus and the risk of severe sequelae of ocular Chlamydia trachomatis infection in Gambians

    Article • Genes & Immunity, March 2007, Springer Science + Business Media

    Dr Martin Holland

  137. Chlamydial Positivity of Nasal Discharge at Baseline Is Associated with Ocular Chlamydial Positivity 2 Months following Azithromycin Treatment

    Article • Investigative Ophthalmology & Visual Science, November 2006, Association for Research in Vision and Ophthalmology (ARVO)

    Dr Martin Holland

  138. Conjunctival FOXP3 Expression in Trachoma: Do Regulatory T Cells Have a Role in Human Ocular Chlamydia trachomatis Infection?

    Article • PLoS Medicine, August 2006, PLOS

    Dr Martin Holland

  139. A coding polymorphism in matrix metalloproteinase 9 reduces risk of scarring sequelae of ocular Chlamydia trachomatisinfection

    Article • BMC Medical Genetics, April 2006, Springer Science + Business Media

    Dr Martin Holland

  140. The Frequency of Chlamydia trachomatis Major Outer Membrane Protein-Specific CD8+ T Lymphocytes in Active Trachoma Is Associated with Current Ocular Infection

    Article • Infection and Immunity, March 2006, ASM Journals

    Dr Martin Holland

  141. Conjunctival Chlamydial 16S Ribosomal RNA Expression in Trachoma: Is Chlamydial Metabolic Activity Required for Disease to Develop?

    Article • Clinical Infectious Diseases, February 2006, Oxford University Press (OUP)

    Dr Martin Holland

  142. Temporal cytokine gene expression patterns in subjects with trachoma identify distinct conjunctival responses associated with infection

    Article • Clinical & Experimental Immunology, November 2005, Wiley

    Dr Martin Holland

  143. Infection with Chlamydia trachomatis after mass treatment of a trachoma hyperendemic community in Tanzania: a longitudinal study

    Article • The Lancet, October 2005, Elsevier

    Dr Martin Holland

  144. Detection, quantification and genotyping of Herpes Simplex Virus in cervicovaginal secretions by real-time PCR: a cross sectional survey

    Article • Virology Journal, August 2005, Springer Science + Business Media

    Dr Martin Holland

  145. Re-emergence of Chlamydia trachomatis infection after mass antibiotic treatment of a trachoma-endemic Gambian community: a longitudinal study

    Article • The Lancet, April 2005, Elsevier

    Dr Martin Holland

  146. Risk of trachomatous scarring and trichiasis in Gambians varies with SNP haplotypes at the interferon-gamma and interleukin-10 loci

    Article • Genes & Immunity, March 2005, Springer Science + Business Media

    Dr Martin Holland

  147. An index of community ocular Chlamydia trachomatis load for control of trachoma

    Article • Transactions of the Royal Society of Tropical Medicine and Hygiene, March 2005, Oxford University Press (OUP)

    Dr Martin Holland

  148. Mass Treatment and the Effect on the Load ofChlamydia trachomatisInfection in a Trachoma-Hyperendemic Community

    Article • Investigative Ophthalmology & Visual Science, January 2005, Association for Research in Vision and Ophthalmology (ARVO)

    Dr Martin Holland

  149. Th2 induction by Nippostrongylus secreted antigens in mice deficient in B cells, eosinophils or MHC Class I-related receptors

    Article • Immunology Letters, January 2005, Elsevier

    Dr Martin Holland

  150. Cytokine and Fibrogenic Gene Expression in the Conjunctivas of Subjects from a Gambian Community Where Trachoma Is Endemic

    Article • Infection and Immunity, December 2004, ASM Journals

    Dr Martin Holland

  151. Mass Treatment with Single-Dose Azithromycin for Trachoma

    Article • The New England Journal of Medicine and Surgery and the Collateral Branches of Science, November 2004, New England Journal of Medicine (NEJM/MMS)

    Dr Martin Holland

  152. Selective maturation of dendritic cells byNippostrongylus brasiliensis-secreted proteins drives Th2 immune responses

    Article • European Journal of Immunology, November 2004, Wiley

    Dr Martin Holland

  153. Cytokine expression and regulation in skin lesions of leprosy patients in type 1 reactions

    Article • Transactions of the Royal Society of Tropical Medicine and Hygiene, November 2003, Oxford University Press (OUP)

    Dr Martin Holland

  154. Strategies for control of trachoma: observational study with quantitative PCR

    Article • American Journal of Ophthalmology, November 2003, Elsevier

    Dr Martin Holland

  155. Which Members of a Community Need Antibiotics to Control Trachoma? ConjunctivalChlamydia trachomatisInfection Load in Gambian Villages

    Article • Investigative Ophthalmology & Visual Science, October 2003, Association for Research in Vision and Ophthalmology (ARVO)

    Dr Martin Holland

  156. Plasmodium falciparum infection of the placenta affects newborn immune responses

    Article • Clinical & Experimental Immunology, September 2003, Wiley

    Dr Martin Holland

  157. Strategies for control of trachoma: observational study with quantitative PCR

    Article • The Lancet, July 2003, Elsevier

    Dr Martin Holland

  158. Proteins secreted by the parasitic nematodeNippostrongylus brasiliensis act as adjuvants for Th2 responses

    Article • European Journal of Immunology, July 2000, Wiley

    Dr Martin Holland

  159. Vaccination against helminth parasites - the ultimate challenge for vaccinologists?

    Article • Immunological Reviews, October 1999, Wiley

    Dr Martin Holland, Franco Falcone

  160. Jaagsiekte Retrovirus Is Widely Distributed both in T and B Lymphocytes and in Mononuclear Phagocytes of Sheep with Naturally and Experimentally Acquired Pulmonary Adenomatosis

    Article • Journal of Virology, May 1999, ASM Journals

    Dr Martin Holland

  161. Early Interleukin–4: Its Role in the Switch towards a Th2 Response and IgE–Mediated Allergy

    Article • International Archives of Allergy and Immunology, January 1999, Karger Publishers

    Dr Martin Holland, Franco Falcone

  162. Parasite immunity: Pathways for expelling intestinal helminths

    Article • Current Biology, October 1998, Elsevier

    Dr Martin Holland

  163. Antibody Response to the 60‐kDa Chlamydial Heat‐Shock Protein Is Associated with Scarring Trachoma

    Article • The Journal of Infectious Diseases, January 1998, Oxford University Press (OUP)

    Dr Martin Holland

  164. Scarring trachoma is associated with polymorphism in the tumor necrosis factor alpha (TNF-alpha) gene promoter and with elevated TNF-alpha levels in tear fluid

    Article • Infection and Immunity, March 1997, ASM Journals

    Dr Martin Holland

  165. Synthetic peptides based on Chlamydia trachomatis antigens identify cytotoxic T lymphocyte responses in subjects from a trachoma‐endemic population

    Article • Clinical & Experimental Immunology, January 1997, Wiley

    Dr Martin Holland

  166. Jaagsiekte retrovirus establishes a disseminated infection of the lymphoid tissues of sheep affected by pulmonary adenomatosis

    Article • Journal of General Virology, December 1996, Society for General Microbiology

    Professor Massimo Palmarini, Dr Martin Holland

  167. T helper type-1 (Th1)/Th2 profiles of peripheral blood mononuclear cells (PBMC); responses to antigens of Chlamydia trachomatis in subjects with severe trachomatous scarring

    Article • Clinical & Experimental Immunology, September 1996, Wiley

    Dr Martin Holland

  168. HLA Class I and II Polymorphisms and Trachomatous Scarring in a Chlamydia trachomatis-Endemic Population

    Article • The Journal of Infectious Diseases, September 1996, Oxford University Press (OUP)

    Dr Martin Holland

  169. Subjects recovering from human ocular chlamydial infection have enhanced lymphoproliferative responses to chlamydial antigens compared with those of persistently diseased controls

    Article • Infection and Immunity, February 1995, ASM Journals

    Dr Martin Holland

  170. Conjunctival Scarring in Trachoma Is Associated with Depressed Cell-Mediated Immune Responses to Chlamydial Antigens

    Article • The Journal of Infectious Diseases, December 1993, Oxford University Press (OUP)

    Dr Martin Holland

  171. Chlamydia pneumoniae and atherosclerosis

    Article • The Lancet, March 1993, Elsevier

    Dr Martin Holland

  172. Lymphocyte proliferative responses to chlamydial antigens in human chlamydial eye infections

    Article • Clinical & Experimental Immunology, October 1991, Oxford University Press (OUP)

    Dr Martin Holland

  173. Experimental Autoimmune Glomerulonephritis Induced by Homologous and Isologous Glomerular Basement Membrane in Brown-Norway Rats

    Article • Nephrology Dialysis Transplantation, January 1991, Oxford University Press (OUP)

    Dr Martin Holland