All Stories

  1. The GRP78/BiP inhibitor HA15 synergizes with mitotane action against adrenocortical carcinoma cells through convergent activation of ER stress pathways

    Article • Molecular and Cellular Endocrinology, February 2018, Elsevier

    Enzo Lalli

  2. The next step: mechanisms driving adrenocortical carcinoma metastasis

    Article • Endocrine Related Cancer, November 2017, Bioscientifica

    Enzo Lalli, Michaela Luconi

  3. Small non-coding RNAs in endocrinology

    Article • Molecular and Cellular Endocrinology, November 2017, Elsevier

    Enzo Lalli

  4. VAV2: a novel prognostic marker and a druggable target for adrenocortical carcinoma

    Article • Oncotarget, October 2017, Impact Journals, LLC

    Enzo Lalli

  5. Assessment of VAV2 Expression Refines Prognostic Prediction in Adrenocortical Carcinoma

    Article • The Journal of Clinical Endocrinology & Metabolism, July 2017, Endocrine Society

    Enzo Lalli

  6. NR5A1 (nuclear receptor subfamily 5, group A, member 1)

    Article • Atlas of Genetics and Cytogenetics in Oncology and Haematology, June 2017, INIST-CNRS

    Enzo Lalli

  7. The role of p27 in pheochromocytoma development

    Article • Endocrine Abstracts, May 2017, Bioscientifica

    Enzo Lalli

  8. Establishment of a mouse xenograft model of metastatic adrenocortical carcinoma

    Article • Oncotarget, April 2017, Impact Journals, LLC

    Enzo Lalli

  9. The ER-mitochondria couple: In life and death from steroidogenesis to tumorigenesis

    Article • Molecular and Cellular Endocrinology, February 2017, Elsevier

    Enzo Lalli

  10. Modeling Fragile X syndrome in neurogenesis: An unexpected phenotype and a novel tool for future therapies

    Article • Neurogenesis, January 2017, Taylor & Francis

    Enzo Lalli

  11. ER-mitochondria contacts find their FATE

    Article • Cell Cycle, August 2016, Taylor & Francis

    Enzo Lalli

  12. FATE1 antagonizes calcium‐ and drug‐induced apoptosis by uncoupling ER and mitochondria

    Article • EMBO Reports, July 2016, EMBO

    Enzo Lalli

  13. Impact of ACTH Signaling on Transcriptional Regulation of Steroidogenic Genes

    Article • Frontiers in Endocrinology, March 2016, Frontiers

    Enzo Lalli

  14. Local Control of Aldosterone Production and Primary Aldosteronism

    Article • Trends in Endocrinology and Metabolism, March 2016, Elsevier

    Enzo Lalli

  15. Special issue on animal models in endocrine neoplasia

    Article • Molecular and Cellular Endocrinology, February 2016, Elsevier

    Enzo Lalli

  16. 5th International ACC Symposium: An Outlook to Current and Future Research on the Biology of Adrenocortical Carcinoma: Diagnostic and Therapeutic Applications

    Article • Hormones and Cancer, December 2015, Springer Science + Business Media

    Enzo Lalli

  17. Mitotane Revisited: A New Target for an Old Drug

    Article • Endocrinology, November 2015, Endocrine Society

    Enzo Lalli

  18. DAX-1 Expression in Pediatric Rhabdomyosarcomas: Another Immunohistochemical Marker Useful in the Diagnosis of Translocation Positive Alveolar Rhabdomyosarcoma

    Article • PLoS ONE, July 2015, PLOS

    Enzo Lalli

  19. Natural paniceins from mediterranean sponge inhibit the multidrug resistance activity of patched and increase chemotherapy efficiency on melanoma cells

    Article • Oncotarget, June 2015, Impact Journals, LLC

    Enzo Lalli

  20. How genomic studies have improved our understanding of the mechanisms of transcriptional regulation by NR5A nuclear receptors

    Article • Molecular and Cellular Endocrinology, June 2015, Elsevier

    Enzo Lalli

  21. Role of steroidogenic factor-1 in the pathogenesis of adrenocortical tumours

    Article • Endocrine Abstracts, May 2015, Bioscientifica

    Enzo Lalli

  22. Pediatric Adrenocortical Tumors: What They Can Tell Us on Adrenal Development and Comparison with Adult Adrenal Tumors

    Article • Frontiers in Endocrinology, February 2015, Frontiers

    Enzo Lalli

  23. Genome-Wide Paternal Uniparental Disomy as a Cause of Beckwith-Wiedemann Syndrome Associated with Recurrent Virilizing Adrenocortical Tumors

    Article • Hormone and Metabolic Research, November 2014, Thieme Publishing Group

    Enzo Lalli

  24. Two-pore domain potassium channels in the adrenal cortex

    Article • Pflügers Archiv - European Journal of Physiology, October 2014, Springer Science + Business Media

    Enzo Lalli

  25. Vanin-1 Inactivation Antagonizes the Development of Adrenocortical Neoplasia inSf-1Transgenic Mice

    Article • Endocrinology, July 2014, Endocrine Society

    Enzo Lalli

  26. Role of Orphan Nuclear Receptor DAX-1/NR0B1 in Development, Physiology, and Disease

    Article • Advances in Biology, January 2014, Hindawi Publishing Corporation

    Enzo Lalli

  27. Lack of long-lasting effects of mitotane adjuvant therapy in a mouse xenograft model of adrenocortical carcinoma

    Article • Molecular and Cellular Endocrinology, December 2013, Elsevier

    Enzo Lalli

  28. Genomic Analysis of Sexual Dimorphism of Gene Expression in the Mouse Adrenal Gland

    Article • Hormone and Metabolic Research, August 2013, Thieme Publishing Group

    Enzo Lalli

  29. Severe Hyperaldosteronism in Neonatal Task3 Potassium Channel Knockout Mice Is Associated With Activation of the Intraadrenal Renin-Angiotensin System

    Article • Endocrinology, August 2013, Endocrine Society

    Enzo Lalli

  30. Integrative analysis of SF-1 transcription factor dosage impact on genome-wide binding and gene expression regulation

    Article • Nucleic Acids Research, August 2013, Oxford University Press (OUP)

    Enzo Lalli

  31. Diagnostic and prognostic role of steroidogenic factor 1 in adrenocortical carcinoma: a validation study focusing on clinical and pathologic correlates

    Article • Human Pathology, May 2013, Elsevier

    Enzo Lalli

  32. Efficacy of the novel dual PI3-kinase/mTOR inhibitor NVP-BEZ235 in a preclinical model of adrenocortical carcinoma

    Article • Molecular and Cellular Endocrinology, November 2012, Elsevier

    Enzo Lalli

  33. Task3 Potassium Channel Gene Invalidation Causes Low Renin and Salt-Sensitive Arterial Hypertension

    Article • Endocrinology, October 2012, Endocrine Society

    Enzo Lalli

  34. Dkk3 is a component of the genetic circuitry regulating aldosterone biosynthesis in the adrenal cortex

    Article • Human Molecular Genetics, August 2012, Oxford University Press (OUP)

    Enzo Lalli

  35. SNP Array Profiling of Childhood Adrenocortical Tumors Reveals Distinct Pathways of Tumorigenesis and Highlights Candidate Driver Genes

    Article • The Journal of Clinical Endocrinology & Metabolism, July 2012, Endocrine Society

    Enzo Lalli

  36. Identity by Descent Mapping of Founder Mutations in Cancer Using High-Resolution Tumor SNP Data

    Article • PLoS ONE, May 2012, PLOS

    Enzo Lalli

  37. Adrenal Cancer: Scientific Advances

    Article • Molecular and Cellular Endocrinology, March 2012, Elsevier

    Enzo Lalli

  38. Dysregulation of microRNAs in adrenocortical tumors

    Article • Molecular and Cellular Endocrinology, March 2012, Elsevier

    Enzo Lalli

  39. Adrenal Cancer: Clinical Advances

    Article • Hormones and Cancer, December 2011, Springer Science + Business Media

    Enzo Lalli

  40. Aldosterone-Producing Adenoma Formation in the Adrenal Cortex Involves Expression of Stem/Progenitor Cell Markers

    Article • Endocrinology, December 2011, Endocrine Society

    Enzo Lalli

  41. Genetics and genomics of childhood adrenocortical tumors

    Article • Molecular and Cellular Endocrinology, April 2011, Elsevier

    Enzo Lalli

  42. Increased Incidence of Choroid Plexus Carcinoma Due to the Germline TP53 R337H Mutation in Southern Brazil

    Article • PLoS ONE, March 2011, PLOS

    Enzo Lalli

  43. The Wnt/beta-catenin pathway in adrenocortical development and cancer

    Article • Molecular and Cellular Endocrinology, January 2011, Elsevier

    Enzo Lalli

  44. Gonadotropin-Dependent Precocious Puberty in a Patient with X-Linked Adrenal Hypoplasia Congenita Caused by a Novel DAX-1 Mutation

    Article • Hormone Research in Paediatrics, January 2011, Karger Publishers

    Enzo Lalli

  45. Adrenal cortex ontogenesis

    Article • Best Practice & Research Clinical Endocrinology & Metabolism, December 2010, Elsevier

    Enzo Lalli

  46. Targeting DAX-1 in embryonic stem cells and cancer

    Article • Expert Opinion on Therapeutic Targets, January 2010, Informa Healthcare

    Enzo Lalli

  47. Identification and Characterization of Steroidogenic Factor-1 Inverse Agonists

    Article • January 2010, Elsevier

    Enzo Lalli

  48. Dax-1 Knockdown in Mouse Embryonic Stem Cells Induces Loss of Pluripotency and Multilineage Differentiation

    Article • Stem Cells, July 2009, Wiley

    Enzo Lalli

  49. Inhibition of Adrenocortical Carcinoma Cell Proliferation by Steroidogenic Factor-1 Inverse Agonists

    Article • The Journal of Clinical Endocrinology & Metabolism, June 2009, Endocrine Society

    Enzo Lalli

  50. Inhibition of Adrenocortical Carcinoma Cell Proliferation by Steroidogenic Factor-1 Inverse Agonists

    Article • Molecular Endocrinology, May 2009, Endocrine Society

    Enzo Lalli

  51. Inhibition of Adrenocortical Carcinoma Cell Proliferation by Steroidogenic Factor-1 Inverse Agonists

    Article • Endocrine Reviews, May 2009, Endocrine Society

    Enzo Lalli

  52. Differential Effects of High and Low Steroidogenic Factor-1 Expression on CYP11B2 Expression and Aldosterone Production in Adrenocortical Cells

    Article • Endocrinology, March 2009, Endocrine Society

    Enzo Lalli

  53. FRAXE-associated mental retardation protein (FMR2) is an RNA-binding protein with high affinity for G-quartet RNA forming structure

    Article • Nucleic Acids Research, January 2009, Oxford University Press (OUP)

    Enzo Lalli

  54. The T cell factor/β-Catenin Antagonist PKF115–584 Inhibits Proliferation of Adrenocortical Carcinoma Cells

    Article • The Journal of Clinical Endocrinology & Metabolism, August 2008, Endocrine Society

    Enzo Lalli

  55. Increased Steroidogenic Factor-1 Dosage Triggers Adrenocortical Cell Proliferation and Cancer

    Article • Molecular Endocrinology, December 2007, Endocrine Society

    Enzo Lalli

  56. Partial defects in transcriptional activity of two novel DAX-1 mutations in childhood-onset adrenal hypoplasia congenita

    Article • Clinical Endocrinology, November 2006, Wiley

    Enzo Lalli

  57. Transcriptional Regulation of the Glucose-6-phosphatase Gene by cAMP/Vasoactive Intestinal Peptide in the Intestine

    Article • Journal of Biological Chemistry, August 2006, American Society for Biochemistry & Molecular Biology (ASBMB)

    Enzo Lalli

  58. SF-1 overexpression in childhood adrenocortical tumours

    Article • European Journal of Cancer, May 2006, Elsevier

    Enzo Lalli

  59. The orphan nuclear receptor DAX1 is up-regulated by the EWS/FLI1 oncoprotein and is highly expressed in Ewing tumors

    Article • International Journal of Cancer, October 2005, Wiley

    Enzo Lalli

  60. Extracellular Matrix and Hormones Modulate DAX-1 Localization in the Human Fetal Adrenal Gland

    Article • The Journal of Clinical Endocrinology & Metabolism, September 2005, Endocrine Society

    Enzo Lalli

  61. Amplification of the Steroidogenic Factor 1 Gene in Childhood Adrenocortical Tumors

    Article • The Journal of Clinical Endocrinology & Metabolism, February 2005, Endocrine Society

    Enzo Lalli

  62. Heat Shock Affects Trafficking of DAX-1 by Inducing Its Rapid and Reversible Cytoplasmic Localization

    Article • Endocrine, January 2005, Springer Science + Business Media

    Enzo Lalli

  63. DAX-1, an Unusual Orphan Receptor at the Crossroads of Steroidogenic Function and Sexual Differentiation

    Article • Molecular Endocrinology, August 2003, Endocrine Society

    Enzo Lalli

  64. Regulation of Niemann-Pick C1 Gene Expression by the 3′5′-Cyclic Adenosine Monophosphate Pathway in Steroidogenic Cells

    Article • Molecular Endocrinology, April 2003, Endocrine Society

    Enzo Lalli

  65. DAX-1

    Article • January 2002, Wiley

    Enzo Lalli

  66. Regulation of Steroidogenesis and the Steroidogenic Acute Regulatory Protein by a Member of the cAMP Response-Element Binding Protein Family

    Article • Molecular Endocrinology, January 2002, Endocrine Society

    Enzo Lalli

  67. Heat Shock Interferes with Steroidogenesis by Reducing Transcription of the Steroidogenic Acute Regulatory Protein Gene

    Article • Molecular Endocrinology, August 2001, Endocrine Society

    Enzo Lalli

  68. DAX-1 and the adrenal cortex

    Article • Current Opinion in Endocrinology and Diabetes, June 1999, Wolters Kluwer Health

    Enzo Lalli

  69. DAX-1 Blocks Steroid Production at Multiple Levels1

    Article • Endocrinology, October 1998, Endocrine Society

    Enzo Lalli

  70. A Transcriptional Silencing Domain in DAX-1 Whose Mutation Causes Adrenal Hypoplasia Congenita

    Article • Molecular Endocrinology, December 1997, Endocrine Society

    Enzo Lalli

  71. Coupling Signal Transduction to Transcription: The Nuclear Response to cAMP

    Article • January 1997, Springer Science + Business Media

    Enzo Lalli

  72. 6 Coupling transcription to signaling pathways

    Article • January 1997, Elsevier

    Enzo Lalli

  73. DNA ploidy analysis of squamous cell carcinomas of the oral and maxillofacial region

    Article • Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology, September 1996, Elsevier

    Enzo Lalli

  74. CREM

    Article • January 1996, Springer Science + Business Media

    Enzo Lalli

  75. CREM, a master-switch in the nuclear response to cAMP signaling

    Article • January 1995, Springer Science + Business Media

    Enzo Lalli

  76. An unusual member of the nuclear hormone receptor superfamily responsible for X-linked adrenal hypoplasia congenita

    Article • Nature, December 1994, Springer Science + Business Media

    Enzo Lalli

  77. Inducibility and negative autoregulation of CREM: An alternative promoter directs the expression of ICER, an early response repressor

    Article • Cell, December 1993, Elsevier

    Enzo Lalli

  78. Nuclear response to cyclic AMP: central role of transcription factor CREM (cyclic-AMP-responsive-element modulator)

    Article • Biochemical Society Transactions, November 1993, Portland Press Ltd.

    Enzo Lalli

  79. In situ hybridization in suspension and flow cytometry as a tool for the study of gene expression

    Article • Analytical Biochemistry, December 1992, Elsevier

    Enzo Lalli

  80. Serum markers of immune activation and liver allograft rejection

    Article • Digestive Diseases and Sciences, July 1992, Springer Science + Business Media

    Mariagrazia Uguccioni, Enzo Lalli