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  1. CR4056, a first-in-class Imidazoline I2 ligand, counteracts osteoarthritis chronic pain in rats
  2. CR4056, a new analgesic I2 ligand, is highly effective against bortezomib-induced painful neuropathy in rats
  3. Analgesic efficacy of CR4056, a novel imidazoline-2 receptor ligand, in rat models of inflammatory and neuropathic pain