All Stories

  1. Advances in Natural and Bio-Inspired Nanoparticles for the Treatment of Cardiovascular Diseases

    Article • Nanomaterials, November 2023, MDPI AG

    Professor Ille C Gebeshuber, Manuela Calin

  2. Tri-Component Hydrogel as Template for Nanocrystalline Hydroxyapatite Deposition Using Alternate Soaking Method for Bone Tissue Engineering Applications

    Article • Gels, November 2023, MDPI AG

    Manuela Calin

  3. Chemical Attachment of 5-Nitrosalicylaldimine Motif to Silatrane Resulting in an Organic–Inorganic Structure with High Medicinal Significance

    Article • Pharmaceutics, December 2022, MDPI AG

    Manuela Calin

  4. Antitumor Properties of a New Macrocyclic Tetranuclear Oxidovanadium(V) Complex with 3-Methoxysalicylidenvaline Ligand

    Article • Biomedicines, May 2022, MDPI AG

    Manuela Calin

  5. Bio-Responsive Carriers for Controlled Delivery of Doxorubicin to Cancer Cells

    Article • Pharmaceutics, April 2022, MDPI AG

    Manuela Calin

  6. VCAM-1 Targeted Lipopolyplexes as Vehicles for Efficient Delivery of shRNA-Runx2 to Osteoblast-Differentiated Valvular Interstitial Cells; Implications in Calcific Valve Disease Treatment

    Article • International Journal of Molecular Sciences, March 2022, MDPI AG

    Manuela Calin

  7. Development of Dextran-Coated Magnetic Nanoparticles Loaded with Protocatechuic Acid for Vascular Inflammation Therapy

    Article • Pharmaceutics, September 2021, MDPI AG

    Manuela Calin

  8. Synthesis, Characterization, and In Vitro Insulin-Mimetic Activity Evaluation of Valine Schiff Base Coordination Compounds of Oxidovanadium(V)

    Article • Biomedicines, May 2021, MDPI AG

    Manuela Calin

  9. Detection of Vascular Reactive Oxygen Species in Experimental Atherosclerosis by High‐Resolution Near‐Infrared Fluorescence Imaging Using VCAM‐1‐Targeted Liposomes Entrapping a Fluorogenic Redox‐Sensitive Probe

    Article • Oxidative Medicine and Cellular Longevity, January 2021, Wiley

    Manuela Calin

  10. Evaluation of VCAM-1 Targeted Naringenin/Indocyanine Green-Loaded Lipid Nanoemulsions as Theranostic Nanoplatforms in Inflammation

    Article • Pharmaceutics, November 2020, MDPI AG

    Manuela Calin

  11. Nano-Polyplexes Mediated Transfection of Runx2-shRNA Mitigates the Osteodifferentiation of Human Valvular Interstitial Cells

    Article • Pharmaceutics, June 2020, MDPI AG

    Manuela Calin

  12. Functional Role of VCAM-1 Targeted Flavonoid-Loaded Lipid Nanoemulsions in Reducing Endothelium Inflammation

    Article • Pharmaceutics, August 2019, MDPI AG

    Manuela Calin

  13. The impact of photocatalytic Ag/TiO2 and Ag/N-TiO2 nanoparticles on human keratinocytes and epithelial lung cells

    Article • Toxicology, March 2019, Elsevier

    Manuela Calin

  14. Targeted Transfection Using PEGylated Cationic Liposomes Directed Towards P-Selectin Increases siRNA Delivery into Activated Endothelial Cells

    Article • Pharmaceutics, January 2019, MDPI AG

    Manuela Calin

  15. Monocyte/macrophages inflammation is inhibited by a Gi-protein inhibitor encapsulated in liposomes

    Article • International Journal of Nanomedicine, December 2017, Dove Medical Press

    Ileana Manduteanu, mariana Deleanu, Manuela Calin

  16. Biopolymers/poly(ε-caprolactone)/polyethylenimine functionalized nano-hydroxyapatite hybrid cryogel: Synthesis, characterization and application in gene delivery

    Article • Materials Science and Engineering C, December 2017, Elsevier

    Manuela Calin

  17. Emerging Nanocarriers-based Approaches to Diagnose and Red uce Vascular Inflammation in Atherosclerosis

    Article • Current Medicinal Chemistry, March 2017, Bentham Science Publishers

    Manuela Calin

  18. Transfection-capable polycationic nanovectors which include PEGylated-cyclodextrin structural units: a new synthesis pathway

    Article • Journal of Materials Chemistry B, January 2017, Royal Society of Chemistry

    Manuela Calin

  19. Amendment of the cytokine profile in macrophages subsequent to their interaction with smooth muscle cells: Differential modulation by fractalkine and resistin

    Article • Cytokine, July 2016, Elsevier

    Manuela Calin

  20. Conjugation of curcumin-loaded lipid nanoemulsions with cell-penetrating peptides increases their cellular uptake and enhances the anti-inflammatory effects in endothelial cells

    Article • Journal of Pharmacy and Pharmacology, January 2016, Wiley

    Manuela Calin

  21. P-Selectin Targeted Dexamethasone-Loaded Lipid Nanoemulsions: A Novel Therapy to Reduce Vascular Inflammation

    Article • Mediators of Inflammation, January 2016, Hindawi Publishing Corporation

    Manuela Calin

  22. Dynameric Frameworks for DNA Transfection

    Article • ACS Biomaterials Science & Engineering, December 2015, American Chemical Society (ACS)

    Manuela Calin

  23. Inhibition of chemokine receptor CCR2 reduces sarcoma cell transendothelial migration and metastasis to the lungs

    Article • International Journal of Clinical Pharmacology and Therapeutics, December 2015, Dustri-Verlgag Dr. Karl Feistle

    Manuela Calin

  24. Targeted delivery of CCR2 antagonist to activated pulmonary endothelium prevents metastasis

    Article • Journal of Controlled Release, December 2015, Elsevier

    Manuela Calin

  25. Hybrid fullerene conjugates as vectors for DNA cell-delivery

    Article • Journal of Materials Chemistry B, January 2015, Royal Society of Chemistry

    Manuela Calin

  26. Flexible cyclic siloxane core enhances the transfection efficiency of polyethylenimine-based non-viral gene vectors

    Article • Journal of Materials Chemistry B, January 2015, Royal Society of Chemistry

    Manuela Calin

  27. VCAM-1 directed target-sensitive liposomes carrying CCR2 antagonists bind to activated endothelium and reduce adhesion and transmigration of monocytes

    Article • European Journal of Pharmaceutics and Biopharmaceutics, January 2015, Elsevier

    Manuela Calin

  28. Functional analysis of the fractalkine gene promoter in human aortic smooth muscle cells exposed to proinflammatory conditions

    Article • FEBS Journal, July 2014, Wiley

    Manuela Calin

  29. Subendothelial resistin enhances monocyte transmigration in a co-culture of human endothelial and smooth muscle cells by mechanisms involving fractalkine, MCP-1 and activation of TLR4 and Gi/o proteins signaling

    Article • The International Journal of Biochemistry & Cell Biology, May 2014, Elsevier

    Manuela Calin

  30. Heparin-Anthranoid Conjugates Associated with Nanomagnetite Particles and Their Cytotoxic Effect on Cancer Cells

    Article • Journal of Biomedical Nanotechnology, January 2014, American Scientific Publishers

    Manuela Calin

  31. Monocytes and smooth muscle cells cross-talk activates STAT3 and induces resistin and reactive oxygen species and production

    Article • Journal of Cellular Biochemistry, August 2013, Wiley

    Manuela Calin

  32. Stem Cell Regenerative Potential Combined with Nanotechnology and Tissue Engineering for Myocardial Regeneration

    Article • Current Stem Cell Research & Therapy, May 2013, Bentham Science Publishers

    Manuela Calin

  33. Inflammatory effects of resistin on human smooth muscle cells: up-regulation of fractalkine and its receptor, CX3CR1 expression by TLR4 and Gi-protein pathways

    Article • Cell and Tissue Research, October 2012, Springer Science + Business Media

    Manuela Calin

  34. A novel pro-inflammatory mechanism of action of resistin in human endothelial cells: Up-regulation of SOCS3 expression through STAT3 activation

    Article • Biochemical and Biophysical Research Communications, June 2012, Elsevier

    Manuela Calin

  35. Cross talk between smooth muscle cells and monocytes/activated monocytes via CX3CL1/CX3CR1 axis augments expression of pro-atherogenic molecules

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, December 2011, Elsevier

    Manuela Calin

  36. Curcumin and a Morus alba Extract Reduce Pro‐Inflammatory Effects of Resistin in Human Endothelial Cells

    Article • Phytotherapy Research, March 2011, Wiley

    Manuela Calin

  37. High glucose induces enhanced expression of resistin in human U937 monocyte-like cell line by MAPK- and NF-kB-dependent mechanisms; the modulating effect of insulin

    Article • Cell and Tissue Research, December 2010, Springer Science + Business Media

    Manuela Calin

  38. Similar effects of resistin and high glucose on P-selectin and fractalkine expression and monocyte adhesion in human endothelial cells

    Article • Biochemical and Biophysical Research Communications, January 2010, Elsevier

    Manuela Calin

  39. Effect of depletion of monocytes/macrophages on early aortic valve lesion in experimental hyperlipidemia

    Article • Cell and Tissue Research, March 2009, Springer Science + Business Media

    Manuela Calin

  40. Resistin up-regulates fractalkine expression in human endothelial cells: Lack of additive effect with TNF-α

    Article • Biochemical and Biophysical Research Communications, March 2009, Elsevier

    Manuela Calin

  41. High glucose conditions induce upregulation of fractalkine and monocyte chemotactic protein-1 in human smooth muscle cells

    Article • Thrombosis and Haemostasis, November 2008, Schattauer GmbH

    Dr Rory R Koenen, Manuela Calin

  42. Enoxaparin Reduces H<sub>2</sub>O<sub>2</sub>-Induced Activation of Human Endothelial Cells by a Mechanism Involving Cell Adhesion Molecules and Nuclear Transcription Factors

    Article • Pharmacology, January 2007, Karger Publishers

    Manuela Calin

  43. Aspirin and PPAR-α activators inhibit monocyte chemoattractant protein-1 expression induced by high glucose concentration in human endothelial cells

    Article • Vascular Pharmacology, June 2006, Elsevier

    Manuela Calin

  44. Immunoliposomes Directed Toward VCAM-1 Interact Specifically with Activated Endothelial Cells—A Potential Tool for Specific Drug Delivery

    Article • Pharmaceutical Research, August 2005, Springer Science + Business Media

    Manuela Calin

  45. Aspirin rectifies calcium homeostasis, decreases reactive oxygen species, and increases NO production in high glucose-exposed human endothelial cells

    Article • Journal of Diabetes and its Complications, September 2004, Elsevier

    Manuela Calin

  46. Superoxide dismutase entrapped-liposomes restore the impaired endothelium-dependent relaxation of resistance arteries in experimental diabetes

    Article • European Journal of Pharmacology, January 2004, Elsevier

    Professor Adriana Georgescu, Manuela Calin

  47. Effect of enoxaparin on high glucose-induced activation of endothelial cells

    Article • European Journal of Pharmacology, September 2003, Elsevier

    Manuela Calin

  48. Designing of ?intelligent? liposomes for efficient delivery of drugs

    Article • Journal of Cellular and Molecular Medicine, October 2002, Wiley

    Manuela Calin

  49. Binding and uptake of transferrin-bound liposomes targeted to transferrin receptors of endothelial cells

    Article • Vascular Pharmacology, July 2002, Elsevier

    Manuela Calin