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  1. Understanding the Key Determinants of Cardiovascular and Metabolic Disease Progression to Develop Effective Therapeutic Strategies

    Article • Biomolecules, October 2024, MDPI AG

    Professor Adriana Georgescu

  2. The siRNA-mediated knockdown of AP-1 restores the function of the pulmonary artery and the right ventricle by reducing perivascular and interstitial fibrosis and key molecular players in cardiopulmonary disease

    Article • Journal of Translational Medicine, February 2024, Springer Science + Business Media

    Professor Adriana Georgescu

  3. The Effects of Sirna-mediated Knockdown of Ap-1 on Pulmonary Arterial and Right Ventricular Dysfunction Associated With Cardiac and Pulmonary Fibrosis in Cardiopulmonary Disease

    Article • November 2023, Research Square

    Professor Adriana Georgescu

  4. Microvesicle-associated and circulating microRNAs in diabetic dyslipidemia: miR-218, miR-132, miR-143, and miR-21, miR-122, miR-155 have biomarker potential

    Article • Cardiovascular Diabetology, September 2023, Springer Science + Business Media

    Professor Adriana Georgescu

  5. Progress in Biomaterials for Cardiac Tissue Engineering and Regeneration

    Article • Polymers, February 2023, MDPI AG

    Prof. Elisabeta Badila, Professor Adriana Georgescu

  6. Cardiovascular Disease as a Consequence or a Cause of Cancer: Potential Role of Extracellular Vesicles

    Article • Biomolecules, February 2023, MDPI AG

    Prof. Elisabeta Badila, Professor Adriana Georgescu

  7. Stem cell‐derived extracellular vesicles reduce the expression of molecules involved in cardiac hypertrophy—In a model of human-induced pluripotent stem cell-derived cardiomyocytes

    Article • Frontiers in Pharmacology, October 2022, Frontiers

    Professor Adriana Georgescu

  8. Microvesicles and Microvesicle-Associated microRNAs Reflect Glioblastoma Regression: Microvesicle-Associated miR-625-5p Has Biomarker Potential

    Article • International Journal of Molecular Sciences, July 2022, MDPI AG

    Professor Adriana Georgescu

  9. Inflammation-induced arterial dysfunction in atherosclerosis; the modulating action of mesenchymal stem cell-derived extracellular vesicles

    Article • Cardiovascular Research, June 2022, Oxford University Press (OUP)

    Professor Adriana Georgescu

  10. MicroRNAs in circulating microvesicles and plasma as biomarkers that complement the clinical diagnosis of diabetic dyslipidemia and its complications

    Article • Cardiovascular Research, June 2022, Oxford University Press (OUP)

    Professor Adriana Georgescu

  11. VLA4-Enhanced Allogeneic Endothelial Progenitor Cell-Based Therapy Preserves the Aortic Valve Function in a Mouse Model of Dyslipidemia and Diabetes

    Article • Pharmaceutics, May 2022, MDPI AG

    Professor Adriana Georgescu

  12. Therapeutic Potential of Stem Cell-Derived Extracellular Vesicles on Atherosclerosis-Induced Vascular Dysfunction and Its Key Molecular Players

    Article • Frontiers in Cell and Developmental Biology, March 2022, Frontiers

    Professor Adriana Georgescu

  13. The Multifaceted Role of Extracellular Vesicles in Glioblastoma: microRNA Nanocarriers for Disease Progression and Gene Therapy

    Article • Pharmaceutics, June 2021, MDPI AG

    Professor Adriana Georgescu

  14. Extracellular vesicles—incorporated microRNA signature as biomarker and diagnosis of prediabetes state and its complications

    Article • Reviews in Endocrine and Metabolic Disorders, June 2021, Springer Science + Business Media

    Professor Adriana Georgescu

  15. Extracellular Vesicles: Versatile Nanomediators, Potential Biomarkers and Therapeutic Agents in Atherosclerosis and COVID-19-Related Thrombosis

    Article • International Journal of Molecular Sciences, May 2021, MDPI AG

    Professor Adriana Georgescu

  16. Extracellular Vesicles from Adipose Tissue Stem Cells in Diabetes and Associated Cardiovascular Disease; Pathobiological Impact and Therapeutic Potential

    Article • International Journal of Molecular Sciences, December 2020, MDPI AG

    Professor Adriana Georgescu

  17. Part One: Extracellular Vesicles as Valuable Players in Diabetic Cardiovascular Diseases

    Article • March 2020, IntechOpen

    Professor Adriana Georgescu

  18. Part Two: Extracellular Vesicles as a Risk Factor in Neurodegenerative Diseases

    Article • March 2020, IntechOpen

    Professor Adriana Georgescu

  19. Intravenous Administration of Allogenic Cell-Derived Microvesicles of Healthy Origins Defends Against Atherosclerotic Cardiovascular Disease Development by a Direct Action on Endothelial Progenitor Cells

    Article • Cells, February 2020, MDPI AG

    Professor Adriana Georgescu, Prof. Elisabeta Badila

  20. Integrins α4β1 and αVβ3 are Reduced in Endothelial Progenitor Cells from Diabetic Dyslipidemic Mice and May Represent New Targets for Therapy in Aortic Valve Disease

    Article • Cell Transplantation, January 2020, SAGE Publications

    Professor Adriana Georgescu

  21. Hypertension Associated With Hyperlipidemia Induced Different MicroRNA Expression Profiles in Plasma, Platelets, and Platelet-Derived Microvesicles; Effects of Endothelial Progenitor Cell Therapy

    Article • Frontiers in Medicine, December 2019, Frontiers

    Professor Adriana Georgescu

  22. Diabetes-induced early molecular and functional changes in aortic heart valves in a murine model of atherosclerosis

    Article • Diabetes and Vascular Disease Research, September 2019, SAGE Publications

    Professor Adriana Georgescu

  23. Early Diabetes Induces Alterations In Endothelial Progenitor Cell Phenotype And Homing In Mice Susceptible To Atherosclerosis

    Article • Atherosclerosis, August 2019, Elsevier

    Professor Adriana Georgescu

  24. Platelets of Healthy Origins Promote Functional Improvement of Atherosclerotic Endothelial Progenitor Cells

    Article • Frontiers in Pharmacology, April 2019, Frontiers

    Professor Adriana Georgescu, Prof. Elisabeta Badila

  25. Sera of Obese Type 2 Diabetic Patients Undergoing Metabolic Surgery Instead of Conventional Treatment Exert Beneficial Effects on Beta Cell Survival and Function: Results of a Randomized Clinical Study

    Article • Obesity Surgery, January 2019, Springer Science + Business Media

    Professor Adriana Georgescu

  26. The Distinct Effects of Palmitic and Oleic Acid on Pancreatic Beta Cell Function: The Elucidation of Associated Mechanisms and Effector Molecules

    Article • Frontiers in Pharmacology, January 2019, Frontiers

    Professor Adriana Georgescu

  27. Circulating ectosomes: Determination of angiogenic microRNAs in type 2 diabetes

    Article • Theranostics, January 2018, Ivyspring International Publisher

    Professor Adriana Georgescu

  28. Understanding the functional role of microRNA-214-3p in atherosclerosis for the identification of novel targeted therapies to prevent or reverse endothelial cell dysfunction and stimulate autophagy

    Article • Acta Physiologica, December 2017, Wiley

    Professor Adriana Georgescu

  29. Endothelial progenitor cells - derived microparticles reproduce the favorable role of their parent cells of healthy origins in the treatment of atherosclerosis via microrna transfer

    Article • Atherosclerosis, August 2017, Elsevier

    Professor Adriana Georgescu

  30. Role of microparticles as microrna messengers in reestablishing of atherosclerosis-associated endothelial progenitor cell dysfunction

    Article • Atherosclerosis, August 2017, Elsevier

    Professor Adriana Georgescu

  31. Microparticles of healthy origins improve endothelial progenitor cell dysfunction via microRNA transfer in an atherosclerotic hamster model

    Article • Acta Physiologica, June 2017, Wiley

    Professor Adriana Georgescu

  32. Endothelial Progenitor Cell Dysfunction in the Pathogenesis of Vascular Complications of Diabetes

    Article • January 2017, Springer Science + Business Media

    Professor Adriana Georgescu

  33. Microparticles: From Biogenesis to Biomarkers and Diagnostic Tools in Cardiovascular Disease

    Article • Current Stem Cell Research & Therapy, December 2016, Bentham Science Publishers

    Professor Adriana Georgescu

  34. Role of MicroRNA in Endothelial Dysfunction and Hypertension

    Article • Current Hypertension Reports, November 2016, Springer Science + Business Media

    Professor Adriana Georgescu

  35. Effects of transplanted circulating endothelial progenitor cells and platelet microparticles in atherosclerosis development

    Article • Biology of the Cell, April 2016, Wiley

    Professor Adriana Georgescu

  36. Vascular complications in diabetes: Microparticles and microparticle associated microRNAs as active players

    Article • Biochemical and Biophysical Research Communications, March 2016, Elsevier

    Professor Adriana Georgescu, Prof. Elisabeta Badila

  37. Midkine proteins in cardio-vascular disease.

    Article • European Journal of Pharmacology, September 2015, Elsevier

    Professor Adriana Georgescu, Prof. Elisabeta Badila

  38. Lack of TAFI increases brain damage and microparticle generation after thrombolytic therapy in ischemic stroke

    Article • Thrombosis Research, August 2015, Elsevier

    Professor Adriana Georgescu

  39. Interaction of platelets with endothelial progenitor cells in the experimental atherosclerosis: Role of transplanted endothelial progenitor cells and platelet microparticles

    Article • Biology of the Cell, April 2015, Wiley

    Professor Adriana Georgescu

  40. Microparticles and endothelial progenitor cells: a critical ratio in vascular atherosclerosis

    Article • Atherosclerosis, August 2014, Elsevier

    Professor Adriana Georgescu

  41. Activation profile of dorsal root ganglia Iba-1 (+) macrophages varies with the type of lesion in rats

    Article • Acta Histochemica, October 2013, Elsevier

    Professor Adriana Georgescu

  42. Irbesartan administration therapeutically influences circulating endothelial progenitor cell and microparticle mobilization by involvement of pro-inflammatory cytokines

    Article • European Journal of Pharmacology, July 2013, Elsevier

    Professor Adriana Georgescu

  43. Circulating Endothelial Progenitor Cell and Platelet Microparticle Impact on Platelet Activation in Hypertension Associated with Hypercholesterolemia

    Article • PLoS ONE, January 2013, PLOS

    Professor Adriana Georgescu

  44. Collagen—Dexamethasone and Collagen-D3Scaffolds for Bone Tissue Engineering

    Article • Molecular Crystals and Liquid Crystals, April 2012, Taylor & Francis

    Professor Adriana Georgescu

  45. Circulating microparticles and endothelial progenitor cells in atherosclerosis: pharmacological effects of irbesartan

    Article • Journal of Thrombosis and Haemostasis, March 2012, Wiley

    Professor Adriana Georgescu, Prof. Elisabeta Badila

  46. Platelet dysfunction in vascular pathologies and how can it be treated

    Article • Thrombosis Research, February 2012, Elsevier

    Professor Adriana Georgescu

  47. The promise of EPC-based therapies on vascular dysfunction in diabetes

    Article • European Journal of Pharmacology, November 2011, Elsevier

    Professor Adriana Georgescu

  48. Enoxaparin reduces adrenergic contraction of resistance arterioles in aging and in aging associated with diabetes via engagement of MAP kinase pathway

    Article • Blood Coagulation & Fibrinolysis, June 2011, Wolters Kluwer Health

    Professor Adriana Georgescu

  49. Dysfunction of human subcutaneous fat arterioles in obesity alone or obesity associated with Type 2 diabetes

    Article • Clinical Science, January 2011, Portland Press Ltd.

    Professor Adriana Georgescu

  50. Vascular dysfunction in diabetes: The endothelial progenitor cells as new therapeutic strategy

    Article • World Journal of Diabetes, January 2011, Baishideng Publishing Group Co., Limited (formerly WJG Press)

    Professor Adriana Georgescu

  51. Integration Properties of Wharton’s Jelly-derived Novel Mesenchymal Stem Cells into Ventricular Slices of Murine Hearts

    Article • Cellular Physiology and Biochemistry, January 2011, Karger Publishers

    Professor Adriana Georgescu

  52. Platelet activation in hypertension associated with hypercholesterolemia: effects of irbesartan

    Article • Journal of Thrombosis and Haemostasis, January 2011, Wiley

    Professor Adriana Georgescu

  53. Intraplatelet Oxidative/Nitrative Stress: Inductors, Consequences, and Control

    Article • Trends in Cardiovascular Medicine, October 2010, Elsevier

    Professor Adriana Georgescu

  54. MS357 IRBESARTAN REDUCES PLATELET ACTIVATION IN HYPERTENSIVE-HYPERCHOLESTEROLEMIC HAMSTER

    Article • Atherosclerosis Supplements, June 2010, Elsevier

    Professor Adriana Georgescu

  55. W55 RATIO OF MICROPARTICLES TO ENDOTHELIAL PROGENITOR CELLS, A MARKER OF VASCULAR DYSFUNCTION INDUCED BY COMBINED HYPERTENSION AND HYPERCHOLESTEROLEMIA; IRBERSARTAN EFFECT

    Article • Atherosclerosis Supplements, June 2010, Elsevier

    Professor Adriana Georgescu

  56. Increased Vitreous Microparticles in Diabetic Retinopathy

    Article • Diabetes, December 2009, American Diabetes Association

    Professor Adriana Georgescu

  57. Long-term high glucose concentration influences Akt, ERK1/2, and PTP1B protein expression in human aortic smooth muscle cells

    Article • Biochemical and Biophysical Research Communications, October 2009, Elsevier

    Professor Adriana Georgescu

  58. Chronic venous insufficiency is associated with elevated level of circulating microparticles

    Article • Journal of Thrombosis and Haemostasis, September 2009, Wiley

    Professor Adriana Georgescu

  59. Nebivolol Induces a Hyperpolarizing Effect on Smooth Muscle Cells in the Mouse Renal Artery by Activation of Beta-2-Adrenoceptors

    Article • Pharmacology, October 2007, Karger Publishers

    Professor Adriana Georgescu, Prof. Elisabeta Badila

  60. Protective effects of nebivolol and reversal of endothelial dysfunction in diabetes associated with hypertension

    Article • European Journal of Pharmacology, September 2007, Elsevier

    Professor Adriana Georgescu, Prof. Elisabeta Badila

  61. LB-PO-856 STRUCTURAL AND FUNCTIONAL ASSESSMENT OF SMALL ARTERIES IN OBESITY AND TYPE 2 DIABETES

    Article • Atherosclerosis Supplements, June 2007, Elsevier

    Professor Adriana Georgescu

  62. Effect of gap junction uncoupler heptanol on resistance arteries reactivity in experimental models of diabetes, hyperlipemia and hyperlipemia-diabetes

    Article • Vascular Pharmacology, June 2006, Elsevier

    Professor Adriana Georgescu

  63. Detection of DNA-bound advanced glycation end-products by immunoaffinity chromatography coupled to HPLC-diode array detection

    Article • Molecular Nutrition & Food Research, April 2006, Wiley

    Professor Adriana Georgescu

  64. The cellular mechanisms involved in the vasodilator effect of nebivolol on the renal artery

    Article • European Journal of Pharmacology, January 2005, Elsevier

    Professor Adriana Georgescu, Prof. Elisabeta Badila

  65. Double transgenic mice with Type 1 diabetes mellitus develop somatic, metabolic and vascular disorders

    Article • Journal of Cellular and Molecular Medicine, July 2004, Wiley

    Professor Adriana Georgescu

  66. Superoxide dismutase entrapped-liposomes restore the impaired endothelium-dependent relaxation of resistance arteries in experimental diabetes

    Article • European Journal of Pharmacology, January 2004, Elsevier

    Professor Adriana Georgescu, Manuela Calin

  67. The contractile response of the mesenteric resistance arteries to prostaglandin F2α; effects of simultaneous hyperlipemia-diabetes

    Article • Fundamental and Clinical Pharmacology, December 2003, Wiley

    Professor Adriana Georgescu

  68. Enoxaparin—a low molecular weight heparin, restores the altered vascular reactivity of resistance arteries in aged and aged–diabetic hamsters

    Article • Vascular Pharmacology, October 2003, Elsevier

    Professor Adriana Georgescu

  69. Beneficial effects of L -arginine supplementation in experimental hyperlipemia-hyperglycemia in the hamster

    Article • Cell and Tissue Research, April 2002, Springer Science + Business Media

    Professor Adriana Georgescu

  70. Mechanisms of decreased bradykinin- induced vasodilation in experimental hyperlipemia-hyperglycemia: contribution of nitric oxide and Ca2+-activated K+ channels

    Article • Fundamental and Clinical Pharmacology, October 2001, Wiley

    Professor Adriana Georgescu

  71. Age-dependent accumulation of advanced glycation endproducts is accelerated in combined hyperlipidemia and hyperglycemia, a process attenuated by L-arginine

    Article • AGE, January 2000, Springer Science + Business Media

    Professor Adriana Georgescu