All Stories

  1. Redox-sensitive GFP fusions for monitoring the catalytic mechanism and inactivation of peroxiredoxins in living cells

    Article • Redox Biology, April 2018, Elsevier

    Dr Madia Trujillo

  2. Chemistry and Redox Biology of Mycothiol

    Article • Antioxidants & Redox Signaling, February 2018, Mary Ann Liebert Inc

    Dr Madia Trujillo

  3. Biochemistry of Peroxynitrite and Protein Tyrosine Nitration

    Article • Chemical Reviews, February 2018, American Chemical Society (ACS)

    Dr Madia Trujillo

  4. Kinetic Characterization of the Redox Regulation of OhrR

    Article • Free Radical Biology and Medicine, November 2017, Elsevier

    Dr Madia Trujillo

  5. Comparative Analysis of Hydrogen Peroxide and Peroxynitrite Reactivity with Thiols

    Article • October 2017, Taylor & Francis

    Dr Madia Trujillo

  6. Kinetics, subcellular localization, and contribution to parasite virulence of a Trypanosoma cruzi hybrid type A heme peroxidase ( Tc APx-CcP)

    Article • Proceedings of the National Academy of Sciences, February 2017, Proceedings of the National Academy of Sciences

    Dr Madia Trujillo, Professor Dario A. Estrin

  7. Ohr plays a central role in bacterial responses against fatty acid hydroperoxides and peroxynitrite

    Article • Proceedings of the National Academy of Sciences, December 2016, Proceedings of the National Academy of Sciences

    Dr Madia Trujillo

  8. PrxQ B from Mycobacterium tuberculosis is a monomeric, thioredoxin-dependent and highly efficient fatty acid hydroperoxide reductase

    Article • Free Radical Biology and Medicine, December 2016, Elsevier

    Dr Madia Trujillo, Professor Dario A. Estrin

  9. Sensitive detection and estimation of cell-derived peroxynitrite fluxes using fluorescein-boronate

    Article • Free Radical Biology and Medicine, December 2016, Elsevier

    Dr Madia Trujillo

  10. Kinetic Characterization of OhrR from Pseudomonas Aeruginosa and Chromobacterium Violaceum, a Bacterial Transcriptional Repressor Capable to Sense Organic Hydroperoxide

    Article • Free Radical Biology and Medicine, November 2016, Elsevier

    Dr Madia Trujillo

  11. Sensitive Detection and Estimation of Cell-Derived Peroxynitrite Fluxes Using Fluorescein-Boronate

    Article • Free Radical Biology and Medicine, November 2016, Elsevier

    Dr Madia Trujillo

  12. Interplay between oxidant species and energy metabolism

    Article • Redox Biology, August 2016, Elsevier

    Dr Madia Trujillo, Dr. Andres Trostchansky

  13. Impact of human galectin-1 binding to saccharide ligands on dimer dissociation kinetics and structure

    Article • Glycobiology, May 2016, Oxford University Press (OUP)

    Dr Madia Trujillo, Professor Dario A. Estrin

  14. Special issue on “Free Radical and Redox Biochemistry of Thiols”

    Article • Free Radical Research, January 2016, Taylor & Francis

    Dr Madia Trujillo

  15. One- and two-electron oxidation of thiols: mechanisms, kinetics and biological fates

    Article • Free Radical Research, November 2015, Taylor & Francis

    Dr Madia Trujillo

  16. Insights into the mechanism of the reaction between hydrogen sulfide and peroxynitrite

    Article • Free Radical Biology and Medicine, March 2015, Elsevier

    Dr Madia Trujillo

  17. Fluorescein-Boronate as a Useful Fluorescent Probe for the Direct Detection of Peroxynitrite in Living Cells: Characterization and Applications

    Article • Free Radical Biology and Medicine, November 2014, Elsevier

    Dr Madia Trujillo

  18. Nitration Transforms a Sensitive Peroxiredoxin 2 into a More Active and Robust Peroxidase

    Article • Journal of Biological Chemistry, April 2014, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Madia Trujillo

  19. Structural basis of redox-dependent modulation of galectin-1 dynamics and function

    Article • Glycobiology, January 2014, Oxford University Press (OUP)

    Dr Madia Trujillo

  20. Thiol redox biochemistry: insights from computer simulations

    Article • Biophysical Reviews, January 2014, Springer Science + Business Media

    Dr Madia Trujillo

  21. The extraordinary catalytic ability of peroxiredoxins: a combined experimental and QM/MM study on the fast thiol oxidation step

    Article • Chemical Communications, January 2014, Royal Society of Chemistry

    Dr Madia Trujillo, Professor Dario A. Estrin

  22. Mycothiol/Mycoredoxin 1-dependent Reduction of the Peroxiredoxin AhpE fromMycobacterium tuberculosis

    Article • Journal of Biological Chemistry, December 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Madia Trujillo

  23. Mechanism of cysteine oxidation by peroxynitrite: An integrated experimental and theoretical study

    Article • Archives of Biochemistry and Biophysics, November 2013, Elsevier

    Dr Madia Trujillo

  24. Trypanothione: A unique bis-glutathionyl derivative in trypanosomatids

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, May 2013, Elsevier

    Dr Madia Trujillo

  25. Protective effect of diphenyl diselenide against peroxynitrite-mediated endothelial cell death: A comparison with ebselen

    Article • Nitric Oxide, May 2013, Elsevier

    Dr Madia Trujillo, Professor Joao Batista Teixeira Rocha

  26. Peroxynitrite as a Cytotoxic Effector AgainstTrypanosoma Cruzi: Oxidative Killing and Antioxidant Resistance Mechanisms

    Article • April 2013, Wiley

    Dr Madia Trujillo

  27. Molecular basis of intramolecular electron transfer in proteins during radical-mediated oxidations: Computer simulation studies in model tyrosine–cysteine peptides in solution

    Article • Archives of Biochemistry and Biophysics, September 2012, Elsevier

    Daniel Murgida, Dr Madia Trujillo

  28. Kinetics of oxidation of tyrosine by a model alkoxyl radical

    Article • Free Radical Research, June 2012, Taylor & Francis

    Dr Madia Trujillo

  29. Hydroperoxide and peroxynitrite reductase activity of poplar thioredoxin-dependent glutathione peroxidase 5: kinetics, catalytic mechanism and oxidative inactivation

    Article • Biochemical Journal, March 2012, Portland Press Ltd.

    Dr Madia Trujillo

  30. Thiol-Dependent Peroxidases in Mycobacterium tuberculosis Antioxidant Defense

    Article • February 2012, IntechOpen

    Dr Madia Trujillo

  31. Molecular Basis of the Mechanism of Thiol Oxidation by Hydrogen Peroxide in Aqueous Solution: Challenging the SN2 Paradigm

    Article • Chemical Research in Toxicology, February 2012, American Chemical Society (ACS)

    Dr Madia Trujillo

  32. Antioxidant Therapies for Neurodegenerative Diseases: Mechanisms, Current Trends, and Perspectives

    Article • Oxidative Medicine and Cellular Longevity, January 2012, Hindawi Publishing Corporation

    Dr Madia Trujillo

  33. Lipid Peroxidation and Protein Tyrosine Nitration Are Mechanistically Connected: Model Studies With Tyrosine-Containing Transmembrane Peptides

    Article • Free Radical Biology and Medicine, November 2011, Elsevier

    Dr Madia Trujillo

  34. Activation Parameters of a Peroxiredoxin From Mycobacterium Tuberculosis

    Article • Free Radical Biology and Medicine, November 2011, Elsevier

    Dr Madia Trujillo

  35. Kinetic studies of peroxiredoxin 6 from Arenicola marina: Rapid oxidation by hydrogen peroxide and peroxynitrite but lack of reduction by hydrogen sulfide

    Article • Archives of Biochemistry and Biophysics, October 2011, Elsevier

    Dr Madia Trujillo

  36. Oxidizing substrate specificity of Mycobacterium tuberculosis alkyl hydroperoxide reductase E: kinetics and mechanisms of oxidation and overoxidation

    Article • Free Radical Biology and Medicine, July 2011, Elsevier

    Dr Madia Trujillo, Dr. Andres Trostchansky

  37. Factors Affecting Protein Thiol Reactivity and Specificity in Peroxide Reduction

    Article • Chemical Research in Toxicology, March 2011, American Chemical Society (ACS)

    Dr Madia Trujillo

  38. Tryparedoxin peroxidases from Trypanosoma cruzi: High efficiency in the catalytic elimination of hydrogen peroxide and peroxynitrite

    Article • Archives of Biochemistry and Biophysics, March 2011, Elsevier

    Dr Madia Trujillo

  39. Kinetics of reduction of tyrosine phenoxyl radicals by glutathione

    Article • Archives of Biochemistry and Biophysics, February 2011, Elsevier

    Dr Madia Trujillo

  40. Reactivity of hydrogen sulfide with peroxynitrite and other oxidants of biological interest

    Article • Free Radical Biology and Medicine, January 2011, Elsevier

    Dr Madia Trujillo

  41. Lipid Peroxyl Radicals Mediate Tyrosine Dimerization and Nitration in Membranes

    Article • Chemical Research in Toxicology, February 2010, American Chemical Society (ACS)

    Dr Madia Trujillo, Dr Marcos Lopez

  42. Fatty Acid Hydroperoxide Reduction by Mycobacterium tuberculosis Alkyl Hydroperoxide Reductase E

    Article • Free Radical Biology and Medicine, January 2010, Elsevier

    Dr Madia Trujillo

  43. Mechanisms and Biological Consequences of Peroxynitrite-Dependent Protein Oxidation and Nitration

    Article • January 2010, Elsevier

    Dr Madia Trujillo

  44. Thiol and Sulfenic Acid Oxidation of AhpE, the One-Cysteine Peroxiredoxin from Mycobacterium tuberculosis: Kinetics, Acidity Constants, and Conformational Dynamics

    Article • Biochemistry, September 2009, American Chemical Society (ACS)

    Dr Madia Trujillo

  45. The peroxidase and peroxynitrite reductase activity of human erythrocyte peroxiredoxin 2

    Article • Archives of Biochemistry and Biophysics, April 2009, Elsevier

    Dr Madia Trujillo

  46. Peroxynitrite Detoxification and Its Biologic Implications

    Article • Antioxidants & Redox Signaling, September 2008, Mary Ann Liebert Inc

    Dr Madia Trujillo

  47. Kinetic Studies on Peroxynitrite Reduction by Peroxiredoxins

    Article • January 2008, Elsevier

    Dr Madia Trujillo

  48. Pre-steady state kinetic characterization of human peroxiredoxin 5: Taking advantage of Trp84 fluorescence increase upon oxidation

    Article • Archives of Biochemistry and Biophysics, November 2007, Elsevier

    Dr Madia Trujillo

  49. Synthesis, Isomer Characterization, and Anti-Inflammatory Properties of Nitroarachidonate

    Article • Biochemistry, March 2007, American Chemical Society (ACS)

    Dr Madia Trujillo, Dr. Andres Trostchansky

  50. Kinetics of Peroxiredoxins and their Role in the Decomposition of Peroxynitrite

    Article • January 2007, Springer Science + Business Media

    Dr Madia Trujillo

  51. Mechanistic Studies of Peroxynitrite-Mediated Tyrosine Nitration in Membranes Using the Hydrophobic Probe N-t-BOC-l-tyrosine tert-Butyl Ester

    Article • Biochemistry, May 2006, American Chemical Society (ACS)

    Dr Madia Trujillo

  52. The Mycobacterial Thioredoxin Peroxidase Can Act as a One-cysteine Peroxiredoxin

    Article • Journal of Biological Chemistry, May 2006, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Madia Trujillo

  53. Peroxynitrite-derived carbonate and nitrogen dioxide radicals readily react with lipoic and dihydrolipoic acid

    Article • Free Radical Biology and Medicine, July 2005, Elsevier

    Dr Madia Trujillo

  54. Plasmodium falciparum 2-Cys peroxiredoxin reacts with plasmoredoxin and peroxynitrite

    Article • Biological Chemistry, January 2005, De Gruyter

    Dr Madia Trujillo

  55. Homolytic Pathways Drive Peroxynitrite-Dependent Trolox C Oxidation

    Article • Chemical Research in Toxicology, September 2004, American Chemical Society (ACS)

    Dr Madia Trujillo

  56. Inactivation of human Cu,Zn superoxide dismutase by peroxynitrite and formation of histidinyl radical

    Article • Free Radical Biology and Medicine, September 2004, Elsevier

    Dr Madia Trujillo

  57. Trypanosoma bruceiandTrypanosoma cruziTryparedoxin Peroxidases Catalytically Detoxify Peroxynitrite via Oxidation of Fast Reacting Thiols

    Article • Journal of Biological Chemistry, May 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Madia Trujillo

  58. Multiple thioredoxin-mediated routes to detoxify hydroperoxides in Mycobacterium tuberculosis

    Article • Archives of Biochemistry and Biophysics, March 2004, Elsevier

    Dr Madia Trujillo

  59. Reactions of desferrioxamine with peroxynitrite-derived carbonate and nitrogen dioxide radicals

    Article • Free Radical Biology and Medicine, February 2004, Elsevier

    Dr Madia Trujillo

  60. Peroxynitrite formation from biochemical and cellular fluxes of nitric oxide and superoxide

    Article • January 2002, Elsevier

    Dr Madia Trujillo

  61. Peroxynitrite Reaction with the Reduced and the Oxidized Forms of Lipoic Acid: New Insights into the Reaction of Peroxynitrite with Thiols

    Article • Archives of Biochemistry and Biophysics, January 2002, Elsevier

    Dr Madia Trujillo

  62. Xanthine Oxidase-mediated Decomposition ofS-Nitrosothiols

    Article • Journal of Biological Chemistry, April 1998, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Madia Trujillo

  63. Peroxynitrite Reaction with Carbon Dioxide/Bicarbonate: Kinetics and Influence on Peroxynitrite-Mediated Oxidations

    Article • Archives of Biochemistry and Biophysics, September 1996, Elsevier

    Dr Madia Trujillo

  64. Inhibition of superoxide-dependent toxicity by nitric oxide

    Article • Free Radical Biology and Medicine, November 1993, Elsevier

    Dr Madia Trujillo