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  1. Editorial: Insights in experimental pharmacology and drug discovery: 2022

    Article • Frontiers in Pharmacology, August 2023, Frontiers

    Dr. Andres Trostchansky

  2. NO–IL-6/10–IL-1β axis: a new pathway in steatotic and non-steatotic liver grafts from brain-dead donor rats

    Article • Frontiers in Immunology, August 2023, Frontiers

    Dr. Andres Trostchansky

  3. An Overview of Two Old Friends Associated with Platelet Redox Signaling, the Protein Disulfide Isomerase and NADPH Oxidase

    Article • Biomolecules, May 2023, MDPI AG

    Dr. Andres Trostchansky

  4. The Use of Triphenyl Phosphonium Cation Enhances the Mitochondrial Antiplatelet Effect of the Compound Magnolol

    Article • Pharmaceuticals, January 2023, MDPI AG

    Dr. Andres Trostchansky

  5. A Comprehensive Literature Review on Cardioprotective Effects of Bioactive Compounds Present in Fruits of Aristotelia chilensis Stuntz (Maqui)

    Article • Molecules, September 2022, MDPI AG

    Dr. Andres Trostchansky

  6. Energy, protein and redox metabolism underlying adaptive responses in New Zealand versus North American Holstein cows in pasture‐based dairy systems

    Article • Journal of Animal Physiology and Animal Nutrition, August 2022, Wiley

    Dr. Andres Trostchansky

  7. Regulation of platelet function by natural bioactive compounds

    Article • Food Bioscience, August 2022, Elsevier

    Dr. Andres Trostchansky

  8. Physical-Exercise-Induced Antioxidant Effects on the Brain and Skeletal Muscle

    Article • Antioxidants, April 2022, MDPI AG

    Dr. Andres Trostchansky

  9. Detection of Nitro-Conjugated Linoleic Acid and Nitro-oleic Acid in Virgin Olive Oil under Gastric Conditions: Relationship to Cultivar, Fruit Ripening, and Polyphenol Content

    Article • ACS Food Science & Technology, April 2022, American Chemical Society (ACS)

    Dr. Andres Trostchansky

  10. HPLC-MS/MS Oxylipin Analysis of Plasma from Amyotrophic Lateral Sclerosis Patients

    Article • Biomedicines, March 2022, MDPI AG

    Dr. Andres Trostchansky

  11. Regulation of Key Antiplatelet Pathways by Bioactive Compounds with Minimal Bleeding Risk

    Article • International Journal of Molecular Sciences, November 2021, MDPI AG

    Dr. Andres Trostchansky

  12. Antiplatelet Effects of Bioactive Compounds Present in Tomato Pomace

    Article • Current Drug Targets, November 2021, Bentham Science Publishers

    Dr Eduardo Fuentes, Dr. Andres Trostchansky

  13. Olive oil-derived nitro-fatty acids: protection of mitochondrial function in non-alcoholic fatty liver disease

    Article • The Journal of Nutritional Biochemistry, August 2021, Elsevier

    Dr. Andres Trostchansky

  14. The protein disulphide isomerase inhibitor CxxCpep modulates oxidative burst and mitochondrial function in platelets

    Article • Free Radical Biology and Medicine, August 2021, Elsevier

    Dr. Andres Trostchansky

  15. Antiplatelet activity and chemical analysis of leaf and fruit extracts from Aristotelia chilensis

    Article • PLoS ONE, April 2021, PLOS

    Dr Eduardo Fuentes, Dr. Andres Trostchansky

  16. Regulation of arachidonic acid oxidation and metabolism by lipid electrophiles

    Article • Prostaglandins & Other Lipid Mediators, February 2021, Elsevier

    Dr. Andres Trostchansky

  17. Structural considerations on lipoxygenase function, inhibition and crosstalk with nitric oxide pathways

    Article • Biochimie, November 2020, Elsevier

    Dr. Andres Trostchansky

  18. Synthesis and Biological Evaluation of Thio-Derivatives of 2-Hydroxy-1,4-Naphthoquinone (Lawsone) as Novel Antiplatelet Agents

    Article • Frontiers in Chemistry, August 2020, Frontiers

    Dr. Andres Trostchansky

  19. Synthesis of antiplatelet ortho-carbonyl hydroquinones with differential action on platelet aggregation stimulated by collagen or TRAP-6

    Article • European Journal of Medicinal Chemistry, April 2020, Elsevier

    Dr. Andres Trostchansky

  20. Data of detection and characterization of nitrated conjugated-linoleic acid (NO2-cLA) in LDL

    Article • Data in Brief, February 2020, Elsevier

    Dr. Andres Trostchansky

  21. Myricetin, the Main Flavonoid in Syzygium cumini Leaf, Is a Novel Inhibitor of Platelet Thiol Isomerases PDI and ERp5

    Article • Frontiers in Pharmacology, January 2020, Frontiers

    Dr. Andres Trostchansky

  22. Fatty acid nitration in human low-density lipoprotein

    Article • Archives of Biochemistry and Biophysics, January 2020, Elsevier

    Dr. Andres Trostchansky

  23. Role of Platelet Activation and Oxidative Stress in the Evolution of Myocardial Infarction

    Article • Journal of Cardiovascular Pharmacology and Therapeutics, July 2019, SAGE Publications

    Dr Eduardo Fuentes, Dr. Andres Trostchansky

  24. Nitro-fatty acids formation in Virgin Olive Oil during gastric digestion and its relationship to cultivar and fruit ripening

    Article • March 2019, Cold Spring Harbor Laboratory Press

    Dr. Andres Trostchansky

  25. Impaired hepatic mitochondrial function during early lactation in dairy cows: Association with protein lysine acetylation

    Article • PLoS ONE, March 2019, PLOS

    Dr. Andres Trostchansky, Mariana Carriquiry

  26. Corrigendum to “Protective Effects of a Polyphenol-Rich Extract from Syzygium cumini (L.) Skeels Leaf on Oxidative Stress-Induced Diabetic Rats”

    Article • Oxidative Medicine and Cellular Longevity, January 2019, Hindawi Publishing Corporation

    Dr. Andres Trostchansky

  27. Bioactive Lipids in Health and Disease

    Article • January 2019, Springer Science + Business Media

    Dr. Andres Trostchansky

  28. Lipid Metabolism and Signaling in Platelet Function

    Article • January 2019, Springer Science + Business Media

    Dr. Andres Trostchansky

  29. Nitroalkylation of α-Synuclein by Nitro-Oleic Acid: Implications for Parkinson’s Disease

    Article • January 2019, Springer Science + Business Media

    Dr. Andres Trostchansky

  30. Protective Effects of a Polyphenol-Rich Extract from Syzygium cumini (L.) Skeels Leaf on Oxidative Stress-Induced Diabetic Rats

    Article • Oxidative Medicine and Cellular Longevity, June 2018, Hindawi Publishing Corporation

    Dr. Andres Trostchansky

  31. Profile of Arachidonic Acid-Derived Inflammatory Markers and Its Modulation by Nitro-Oleic Acid in an Inherited Model of Amyotrophic Lateral Sclerosis

    Article • Frontiers in Molecular Neuroscience, April 2018, Frontiers

    Dr. Andres Trostchansky

  32. Nitroxide Tempol down-regulates kinase activities associated with NADPH oxidase function in phagocytic cells and potentially decreases their fungicidal response

    Article • Chemico-Biological Interactions, January 2018, Elsevier

    Dr. Andres Trostchansky

  33. Nitroxide 4-hydroxy-2,2′,6,6′-tetramethylpiperidine 1-oxyl (Tempol) inhibits the reductase activity of protein disulfide isomerase via covalent binding to the Cys 400 residue on CXXC redox motif at the a′active site

    Article • Chemico-Biological Interactions, June 2017, Elsevier

    Dr. Andres Trostchansky

  34. Nitroarachidonic acid (NO 2 AA) inhibits protein disulfide isomerase (PDI) through reversible covalent adduct formation with critical cysteines

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, May 2017, Elsevier

    Dr. Andres Trostchansky

  35. Anti-inflammatory signaling actions of electrophilic nitro-arachidonic acid in vascular cells and astrocytes

    Article • Archives of Biochemistry and Biophysics, March 2017, Elsevier

    Dr. Andres Trostchansky

  36. Novel antiplatelet role for a protein disulfide isomerase-targeted peptide: evidence of covalent binding to the C-terminal CGHC redox motif

    Article • Journal of Thrombosis and Haemostasis, February 2017, Wiley

    Dr. Andres Trostchansky

  37. Interplay between Oxidative Stress and Metabolism in Signalling and Disease 2016

    Article • Oxidative Medicine and Cellular Longevity, January 2017, Hindawi Publishing Corporation

    Assistant Professor Hariom Yadav, Dr. Andres Trostchansky

  38. Reciprocal regulation of acetyl-CoA carboxylase 1 and senescence in human fibroblasts involves oxidant mediated p38 MAPK activation

    Article • Archives of Biochemistry and Biophysics, January 2017, Elsevier

    Dr. Andres Trostchansky

  39. Interplay between oxidant species and energy metabolism

    Article • Redox Biology, August 2016, Elsevier

    Dr Madia Trujillo, Dr. Andres Trostchansky

  40. Electrophilic nitro-fatty acids prevent astrocyte-mediated toxicity to motor neurons in a cell model of familial amyotrophic lateral sclerosis via nuclear factor erythroid 2-related factor activation

    Article • Free Radical Biology and Medicine, June 2016, Elsevier

    Dr. Andres Trostchansky

  41. Nitro-Arachidonic Acid Prevents Angiotensin II-Induced Mitochondrial Dysfunction in a Cell Line of Kidney Proximal Tubular Cells

    Article • PLoS ONE, March 2016, PLOS

    Dr. Andres Trostchansky

  42. Interplay between Oxidative Stress and Metabolism in Signalling and Disease

    Article • Oxidative Medicine and Cellular Longevity, January 2016, Hindawi Publishing Corporation

    Assistant Professor Hariom Yadav, Dr. Andres Trostchansky

  43. Potential Role of Protein Disulfide Isomerase in Metabolic Syndrome-Derived Platelet Hyperactivity

    Article • Oxidative Medicine and Cellular Longevity, January 2016, Hindawi Publishing Corporation

    Dr. Andres Trostchansky

  44. Olives and Olive Oil Are Sources of Electrophilic Fatty Acid Nitroalkenes

    Article • PLoS ONE, January 2014, PLOS

    Dr. Andres Trostchansky

  45. Nitro-Fatty Acids: Formation, Redox Signaling, and Therapeutic Potential

    Article • Antioxidants & Redox Signaling, October 2013, Mary Ann Liebert Inc

    Dr. Andres Trostchansky

  46. Nitroarachidonic acid prevents NADPH oxidase assembly and superoxide radical production in activated macrophages

    Article • Free Radical Biology and Medicine, May 2013, Elsevier

    Dr. Andres Trostchansky

  47. Regulation of protein kinase C by nitroarachidonic acid: Impact on human platelet activation

    Article • Archives of Biochemistry and Biophysics, May 2013, Elsevier

    Dr. Andres Trostchansky

  48. Oxidizing substrate specificity of Mycobacterium tuberculosis alkyl hydroperoxide reductase E: kinetics and mechanisms of oxidation and overoxidation

    Article • Free Radical Biology and Medicine, July 2011, Elsevier

    Dr Madia Trujillo, Dr. Andres Trostchansky

  49. 6-Methylnitroarachidonate: A novel esterified nitroalkene that potently inhibits platelet aggregation and exerts cGMP-mediated vascular relaxation

    Article • Free Radical Biology and Medicine, February 2011, Elsevier

    Dr. Andres Trostchansky

  50. Nitroarachidonic Acid, a Novel Peroxidase Inhibitor of Prostaglandin Endoperoxide H Synthases 1 and 2

    Article • Journal of Biological Chemistry, January 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr. Andres Trostchansky

  51. Peroxynitrite-mediated lipid oxidation and nitration: Mechanisms and consequences

    Article • Archives of Biochemistry and Biophysics, April 2009, Elsevier

    Dr. Andres Trostchansky

  52. Macrophage activation induces formation of the anti-inflammatory lipid cholesteryl-nitrolinoleate

    Article • Biochemical Journal, January 2009, Portland Press Ltd.

    Dr. Andres Trostchansky

  53. Nitrated fatty acids: Mechanisms of formation, chemical characterization, and biological properties

    Article • Free Radical Biology and Medicine, June 2008, Elsevier

    Dr. Andres Trostchansky

  54. Nitroalkenes: Synthesis, Characterization, and Effects on Macrophage Activation

    Article • January 2008, Elsevier

    Dr. Andres Trostchansky

  55. Interactions between nitric oxide and peroxynitrite during prostaglandin endoperoxide H synthase-1 catalysis: A free radical mechanism of inactivation

    Article • Free Radical Biology and Medicine, April 2007, Elsevier

    Dr. Andres Trostchansky

  56. Synthesis, Isomer Characterization, and Anti-Inflammatory Properties of Nitroarachidonate

    Article • Biochemistry, March 2007, American Chemical Society (ACS)

    Dr Madia Trujillo, Dr. Andres Trostchansky

  57. Lipid nitration and formation of lipid-protein adducts: biological insights

    Article • Amino Acids, October 2006, Springer Science + Business Media

    Dr. Andres Trostchansky

  58. Interaction with phospholipids modulates α-synuclein nitration and lipid–protein adduct formation

    Article • Biochemical Journal, January 2006, Portland Press Ltd.

    Dr. Andres Trostchansky

  59. Design, synthesis, and biological characterization of potential antiatherogenic nitric oxide releasing tocopherol analogs

    Article • Bioorganic & Medicinal Chemistry, October 2005, Elsevier

    Dr. Andres Trostchansky

  60. Reactivity of Peroxynitrite and Nitric Oxide with LDL

    Article • IUBMB Life, June 2005, Wiley

    Dr. Andres Trostchansky

  61. Septic diaphragmatic dysfunction is prevented by Mn(III)porphyrin therapy and inducible nitric oxide synthase inhibition

    Article • Intensive Care Medicine, September 2004, Springer Science + Business Media

    Dr. Andres Trostchansky

  62. Binding of Xanthine Oxidase to Glycosaminoglycans Limits Inhibition by Oxypurinol

    Article • Journal of Biological Chemistry, July 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr. Andres Trostchansky

  63. Nitric oxide inhibits prooxidant actions of uric acid during copper-mediated LDL oxidation

    Article • Archives of Biochemistry and Biophysics, March 2004, Elsevier

    Dr. Andres Trostchansky

  64. Peroxynitrite-mediated α-tocopherol oxidation in low-density lipoprotein: a mechanistic approach

    Article • Free Radical Biology and Medicine, January 2004, Elsevier

    Dr. Andres Trostchansky

  65. Peroxynitrite flux-mediated LDL oxidation is inhibited by manganese porphyrins in the presence of uric acid

    Article • Free Radical Biology and Medicine, November 2003, Elsevier

    Dr. Andres Trostchansky

  66. Interactions of Nitric Oxide and Peroxynitrite with Low-Density Lipoprotein

    Article • Biological Chemistry, January 2002, De Gruyter

    Dr. Andres Trostchansky

  67. Antioxidant and diffusion properties of nitric oxide in low-density lipoprotein

    Article • January 2002, Elsevier

    Dr. Andres Trostchansky

  68. Formation of Lipid-Protein Adducts in Low-Density Lipoprotein by Fluxes of Peroxynitrite and Its Inhibition by Nitric Oxide

    Article • Archives of Biochemistry and Biophysics, November 2001, Elsevier

    Dr. Andres Trostchansky