All Stories

  1. Effect of ACE1 polymorphism rs1799752 on protein levels of ACE2, the SARS-CoV-2 entry receptor, in alveolar lung epithelium

    Article • ERJ Open Research, February 2021, European Respiratory Society (ERS)

    Prof. Dr. Ken R Bracke

  2. Increased expression of ACE2, the SARS-CoV-2 entry receptor, in alveolar and bronchial epithelium of smokers and COPD subjects

    Article • European Respiratory Journal, July 2020, European Respiratory Society (ERS)

    Prof. Dr. Ken R Bracke

  3. Placental growth factor inhibition targets pulmonary angiogenesis and represents a novel therapy for hepatopulmonary syndrome in mice

    Article • Hepatology, May 2018, Wiley

    Prof. Dr. Ken R Bracke, Xavier Verhelst

  4. Association of innate defense proteins BPIFA1 and BPIFB1 with disease severity in COPD

    Article • International Journal of Chronic Obstructive Pulmonary Disease, December 2017, Dove Medical Press

    Prof. Dr. Ken R Bracke

  5. MicroRNAs as future therapeutic targets in COPD?

    Article • European Respiratory Journal, May 2017, European Respiratory Society (ERS)

    Prof. Dr. Ken R Bracke

  6. Increased levels of enzymes involved in local estradiol synthesis in chronic obstructive pulmonary disease

    Article • Molecular and Cellular Endocrinology, March 2017, Elsevier

    Prof. Dr. Ken R Bracke

  7. Correction: Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD

    Article • Journal of Experimental Medicine, January 2017, Rockefeller University Press

    Prof. Dr. Ken R Bracke, Darcy Wagner

  8. Role of miR-218 in COPD

    Article • American Journal of Respiratory and Critical Care Medicine, January 2017, American Thoracic Society

    Dr Alan Hsu, Prof. Dr. Ken R Bracke, Conjoint Professor Peter Wark

  9. Immunological diversity in phenotypes of chronic lung allograft dysfunction: a comprehensive immunohistochemical analysis

    Article • Transplant International, December 2016, Wiley

    Prof. Dr. Ken R Bracke

  10. LSC Abstract – Association of single nucleotide polymorphisms located in miRNA binding sites with lung function

    Article • September 2016, European Respiratory Society (ERS)

    Prof. Dr. Ken R Bracke

  11. LSC Abstract – microRNA profiling reveals a role for microRNA-218-5p in the pathogenesis of chronic obstructive pulmonary disease

    Article • September 2016, European Respiratory Society (ERS)

    Prof. Dr. Ken R Bracke

  12. LSC Abstract – Association of single nucleotide polymorphisms located in miRNA binding sites with lung function

    Article • September 2016, European Respiratory Society (ERS)

    Prof. Dr. Ken R Bracke

  13. LSC Abstract – MicroRNA profiling reveals a role for microRNA-218-5p in the pathogenesis of chronic obstructive pulmonary disease

    Article • September 2016, European Respiratory Society (ERS)

    Prof. Dr. Ken R Bracke

  14. Aggravation of Allergic Airway Inflammation by Cigarette Smoke in Mice Is CD44-Dependent

    Article • PLoS ONE, March 2016, PLOS

    Prof. Dr. Ken R Bracke

  15. Characterization and Quantification of Innate Lymphoid Cell Subsets in Human Lung

    Article • PLoS ONE, January 2016, PLOS

    Prof. Dr. Ken R Bracke

  16. The Effect of Cigarette Smoke Exposure on the Development of Inflammation in Lungs, Gut and Joints of TNFΔARE Mice

    Article • PLoS ONE, November 2015, PLOS

    Prof. Dr. Ken R Bracke

  17. MicroRNA miR-22 drives TH17 responses in emphysema

    Article • Nature Immunology, October 2015, Nature

    Prof. Dr. Ken R Bracke

  18. Elucidating COPD pathogenesis by large-scale genetic analyses

    Article • The Lancet Respiratory Medicine, October 2015, Elsevier

    Prof. Dr. Ken R Bracke

  19. LSC Abstract – Lack of BMP-6 aggravates pulmonary inflammation in mice after subacute cigarette smoke exposure, but not after chronic exposure

    Article • September 2015, European Respiratory Society (ERS)

    Prof. Dr. Ken R Bracke

  20. Immune cell localization in different compartments of human end-stage cystic fibrosis lungs

    Article • September 2015, European Respiratory Society (ERS)

    Prof. Dr. Ken R Bracke

  21. Expression of estrogen receptors and estrogen metabolism genes in lungs of COPD patients

    Article • September 2015, European Respiratory Society (ERS)

    Prof. Dr. Ken R Bracke

  22. Airway Surface Dehydration Aggravates Cigarette Smoke-Induced Hallmarks of COPD in Mice

    Article • PLoS ONE, June 2015, PLOS

    Prof. Dr. Ken R Bracke

  23. Targeted therapy with inhaled corticosteroids in COPD according to blood eosinophil counts

    Article • The Lancet Respiratory Medicine, June 2015, Elsevier

    Prof. Dr. Ken R Bracke

  24. Transforming Growth Factor-β Superfamily in Obstructive Lung Diseases. More Suspects Than TGF-β Alone

    Article • American Journal of Respiratory Cell and Molecular Biology, June 2015, American Thoracic Society

    Prof. Dr. Ken R Bracke

  25. Non-coding RNAs in the pathogenesis of COPD

    Article • Thorax, May 2015, BMJ

    Prof. Dr. Ken R Bracke

  26. Chronic Obstructive Pulmonary Disease

    Article • January 2015, Elsevier

    Prof. Dr. Ken R Bracke

  27. Expression of citrulline and homocitrulline residues in the lungs of non-smokers and smokers: implications for autoimmunity in rheumatoid arthritis

    Article • Arthritis Research & Therapy, January 2015, Springer Science + Business Media

    Prof. Dr. Ken R Bracke

  28. Targeting Immune Pathways for Therapy in Asthma and Chronic Obstructive Pulmonary Disease

    Article • Annals of the American Thoracic Society, December 2014, American Thoracic Society

    Prof. Dr. Ken R Bracke

  29. Investigation of 5-HT4 receptors in bronchial hyperresponsiveness in cigarette smoke-exposed mice

    Article • Pulmonary Pharmacology & Therapeutics, June 2014, Elsevier

    Prof. Dr. Ken R Bracke

  30. Inflammasomes in Respiratory Disease

    Article • CHEST Journal, May 2014, Elsevier

    Prof. Dr. Ken R Bracke

  31. Role of activin-A in cigarette smoke-induced inflammation and COPD

    Article • European Respiratory Journal, November 2013, European Respiratory Society (ERS)

    Prof. Dr. Ken R Bracke

  32. The Role of Soluble Guanylyl Cyclase in Chronic Obstructive Pulmonary Disease

    Article • American Journal of Respiratory and Critical Care Medicine, October 2013, American Thoracic Society

    Professor Theodoros I Vassilakopoulos, Prof. Dr. Ken R Bracke

  33. Eosinophils in the Spotlight: Eosinophilic airway inflammation in nonallergic asthma

    Article • Nature Medicine, August 2013, Nature

    Prof. Dr. Ken R Bracke

  34. Leptin as regulator of pulmonary immune responses: Involvement in respiratory diseases

    Article • Pulmonary Pharmacology & Therapeutics, August 2013, Elsevier

    Prof. Dr. Ken R Bracke

  35. A1.3 Citrullination in Healthy and Inflamed Lung Tissue as a Priming Site for Autoimmunity in RA

    Article • Annals of the Rheumatic Diseases, February 2013, BMJ

    Prof. Dr. Ken R Bracke

  36. P694 Chronic cigarette smoke exposure alters the murine gut microbiome

    Article • Journal of Crohn s and Colitis, February 2013, Oxford University Press (OUP)

    Prof. Dr. Ken R Bracke

  37. P2Y6 receptor signalling in COPD patients and cigarette smoke-exposed mice

    Article • Pneumologie, November 2012, Thieme Publishing Group

    Prof. Dr. Ken R Bracke

  38. Altered Cigarette Smoke-Induced Lung Inflammation Due to Ablation of Grx1

    Article • PLoS ONE, June 2012, PLOS

    Prof. Dr. Ken R Bracke

  39. Expression Of Interferon Regulatory Factor 8 In Human Lung Dendritic Cell Subsets

    Article • May 2012, American Thoracic Society

    Prof. Dr. Ken R Bracke

  40. Obesity Modulates Pulmonary Immune Response Against Chronic Cigarette Smoke Inhalation In Mice

    Article • May 2012, American Thoracic Society

    Prof. Dr. Ken R Bracke

  41. Role Of ADAM19 And Neuregulin-1 In Muc5ac Expression In Lungs Of Cigarette Smoke-Exposed Mice

    Article • May 2012, American Thoracic Society

    Prof. Dr. Ken R Bracke

  42. Smoke decreases reversible oxidations S-glutathionylation and S-nitrosylation in mice

    Article • Free Radical Research, January 2012, Taylor & Francis

    Prof. Dr. Ken R Bracke

  43. Chronic Rejection Pathology after Orthotopic Lung Transplantation in Mice: The Development of a Murine BOS Model and Its Drawbacks

    Article • PLoS ONE, January 2012, PLOS

    Prof. Dr. Ken R Bracke

  44. Cigarette smoke and the terminal ileum: increased autophagy in murine follicle-associated epithelium and Peyer’s patches

    Article • Histochemistry and Cell Biology, December 2011, Springer Science + Business Media

    Prof. Dr. Ken R Bracke

  45. Exacerbation of cigarette smoke-induced pulmonary inflammation by Staphylococcus aureus Enterotoxin B in mice

    Article • December 2011, Springer Science + Business Media

    Prof. Dr. Ken R Bracke

  46. COPD is associated with reduced pulmonary interstitial expression of pentraxin-3

    Article • European Respiratory Journal, September 2011, European Respiratory Society (ERS)

    Prof. Dr. Ken R Bracke

  47. New insights into the immunology of chronic obstructive pulmonary disease

    Article • The Lancet, September 2011, Elsevier

    Prof. Dr. Ken R Bracke

  48. Role of IL-1  and the Nlrp3/caspase-1/IL-1  axis in cigarette smoke-induced pulmonary inflammation and COPD

    Article • European Respiratory Journal, May 2011, European Respiratory Society (ERS)

    Prof. Dr. Ken R Bracke

  49. Cigarette smoking alters epithelial apoptosis and immune composition in murine GALT

    Article • Laboratory Investigation, May 2011, Nature

    Prof. Dr. Ken R Bracke

  50. Role Of Caspase-7 In Cigarette Smoke-Induced Inflammation In Mice

    Article • May 2011, American Thoracic Society

    Prof. Dr. Ken R Bracke

  51. Effect Of Cigarette Smoke Extract Or TGF-Beta1 On Hyaluronan Production And Hyaluronan Modulating Enzymes In Primary Murine Lung Fibroblasts

    Article • May 2011, American Thoracic Society

    Prof. Dr. Ken R Bracke

  52. Chemr23-Signaling Modulates Cigarette Smoke-Induced Pulmonary Inflammation In Mice

    Article • May 2011, American Thoracic Society

    Prof. Dr. Ken R Bracke

  53. MicroRNA Expression in Induced Sputum of Smokers and Patients with Chronic Obstructive Pulmonary Disease

    Article • American Journal of Respiratory and Critical Care Medicine, April 2011, American Thoracic Society

    Prof. Dr. Ken R Bracke

  54. The Role of ChemR23 in the Induction and Resolution of Cigarette Smoke-Induced Inflammation

    Article • The Journal of Immunology, March 2011, The American Association of Immunologists

    Prof. Dr. Ken R Bracke

  55. A4 Dendritic cells

    Article • January 2011, Springer Science + Business Media

    Prof. Dr. Ken R Bracke

  56. Cigarette smoke induces PTX3 expression in pulmonary veins of mice in an IL-1 dependent manner

    Article • October 2010, Springer Science + Business Media

    Prof. Dr. Ken R Bracke

  57. The role of interleukin-6 in pulmonary and systemic manifestations in a murine model of chronic obstructive pulmonary disease

    Article • Experimental Lung Research, September 2010, Taylor & Francis

    Prof. Dr. Ken R Bracke

  58. Different regulation of cigarette smoke induced inflammation in upper versus lower airways

    Article • July 2010, Springer Science + Business Media

    Prof. Dr. Ken R Bracke

  59. Leptin Modulates Innate and Adaptive Immune Cell Recruitment after Cigarette Smoke Exposure in Mice

    Article • The Journal of Immunology, May 2010, The American Association of Immunologists

    Prof. Dr. Ken R Bracke

  60. Exogenous Administration Of Leptin Restores The Skewed Inflammatory Response In Cigarette Smoke-exposed Ob/ob Mice

    Article • May 2010, American Thoracic Society

    Prof. Dr. Ken R Bracke

  61. Plasmacytoid Dendritic Cells In Pulmonary Lymphoid Follicles Of Patients With COPD

    Article • May 2010, American Thoracic Society

    Prof. Dr. Ken R Bracke

  62. Reduced Expression Of Pentraxin-3 In The Lungs Of Patients With COPD

    Article • May 2010, American Thoracic Society

    Prof. Dr. Ken R Bracke

  63. Staphylococcus Aureus Enterotoxin B Exacerbates Cigarette Smoke-induced Pulmonary Inflammation In Mice

    Article • May 2010, American Thoracic Society

    Prof. Dr. Ken R Bracke

  64. Cigarette Smoke-induced Pentraxin-3 Expression In Lung Endothelial Cells Is Dependent On The IL-1 Pathway

    Article • May 2010, American Thoracic Society

    Prof. Dr. Ken R Bracke

  65. Plasmacytoid dendritic cells in pulmonary lymphoid follicles of patients with COPD

    Article • European Respiratory Journal, March 2010, European Respiratory Society (ERS)

    Prof. Dr. Ken R Bracke

  66. Selective accumulation of langerhans-type dendritic cells in small airways of patients with COPD

    Article • March 2010, Springer Science + Business Media

    Prof. Dr. Ken R Bracke

  67. Increased T-regulatory cells in lungs and draining lymph nodes in a murine model of COPD

    Article • European Respiratory Journal, February 2010, European Respiratory Society (ERS)

    Prof. Dr. Ken R Bracke

  68. CCR7 Modulates Pulmonary and Lymph Node Inflammatory Responses in Cigarette Smoke-Exposed Mice

    Article • The Journal of Immunology, November 2009, The American Association of Immunologists

    Prof. Dr. Ken R Bracke

  69. Concomitant Inhalation of Cigarette Smoke and Aerosolized Protein Activates Airway Dendritic Cells and Induces Allergic Airway Inflammation in a TLR-Independent Way

    Article • The Journal of Immunology, July 2009, The American Association of Immunologists

    Prof. Dr. Ken R Bracke

  70. Lymphoid follicles in (very) severe COPD: beneficial or harmful?

    Article • European Respiratory Journal, June 2009, European Respiratory Society (ERS)

    Prof. Dr. Ken R Bracke

  71. Role of the tachykinin NK1 receptor in a murine model of cigarette smoke-induced pulmonary inflammation

    Article • May 2009, Springer Science + Business Media

    Prof. Dr. Ken R Bracke

  72. IL-6 Family of Cytokines in Lungs of Cigarette Smoke Exposed Wildtype and IL-6 Knockout Mice.

    Article • April 2009, American Thoracic Society

    Prof. Dr. Ken R Bracke

  73. In Vitro Stimulation of Murine Lung Fibroblasts Induces Lymphotoxin-β-Receptor-Mediated Expression of Lymphoid Chemokines.

    Article • April 2009, American Thoracic Society

    Prof. Dr. Ken R Bracke

  74. Cigarette Smoke-Induced Pulmonary Inflammation Is Attenuated in Mice Treated with the NK1Receptor Antagonist RP 67580.

    Article • April 2009, American Thoracic Society

    Prof. Dr. Ken R Bracke

  75. Role of lymphotoxin-  in cigarette smoke-induced inflammation and lymphoid neogenesis

    Article • European Respiratory Journal, January 2009, European Respiratory Society (ERS)

    Prof. Dr. Ken R Bracke

  76. The Role of Dendritic Cells in the Pathogenesis of COPD: Liaison Officers in the Front Line

    Article • COPD Journal of Chronic Obstructive Pulmonary Disease, January 2009, Taylor & Francis

    Prof. Dr. Ken R Bracke

  77. Enhanced pulmonary leptin expression in patients with severe COPD and asymptomatic smokers

    Article • Thorax, October 2008, BMJ

    Prof. Dr. Ken R Bracke

  78. Comment on “Cigarette Smoke-Induced Pulmonary Inflammation Is TLR4/MyD88 and IL-1R1/MyD88 Signaling Dependent”

    Article • The Journal of Immunology, April 2008, The American Association of Immunologists

    Prof. Dr. Ken R Bracke

  79. TNFα receptor genotype influences smoking-induced muscle-fibre-type shift and atrophy in mice

    Article • Acta Neuropathologica, February 2008, Springer Science + Business Media

    Prof. Dr. Ken R Bracke

  80. Cigarette smoke-induced pulmonary inflammation, but not airway remodelling, is attenuated in chemokine receptor 5-deficient mice

    Article • Clinical & Experimental Allergy, August 2007, Wiley

    Prof. Dr. Ken R Bracke

  81. CC-Chemokine Receptors in Chronic Obstructive Pulmonary Disease

    Article • Inflammation & Allergy - Drug Targets, June 2007, Bentham Science Publishers

    Prof. Dr. Ken R Bracke

  82. Cigarette Smoke-Induced Pulmonary Inflammation and Emphysema Are Attenuated in CCR6-Deficient Mice

    Article • The Journal of Immunology, September 2006, The American Association of Immunologists

    Prof. Dr. Ken R Bracke

  83. Different Roles for Human Lung Dendritic Cell Subsets in Pulmonary Immune Defense Mechanisms

    Article • American Journal of Respiratory Cell and Molecular Biology, September 2006, American Thoracic Society

    Prof. Dr. Ken R Bracke

  84. Murine models of COPD

    Article • Pulmonary Pharmacology & Therapeutics, June 2006, Elsevier

    Prof. Dr. Ken R Bracke

  85. Role of apoptosis in the pathogenesis of COPD and pulmonary emphysema

    Article • March 2006, Springer Science + Business Media

    Prof. Dr. Ken R Bracke

  86. Murine TLR4 Is Implicated in Cigarette Smoke-Induced Pulmonary Inflammation

    Article • International Archives of Allergy and Immunology, January 2006, Karger Publishers

    Prof. Dr. Ken R Bracke

  87. Cigarette smoke-induced pulmonary emphysema in scid-mice. Is the acquired immune system required?

    Article • December 2005, Springer Science + Business Media

    Prof. Dr. Ken R Bracke

  88. Matrix metalloproteinases in asthma and COPD

    Article • Current Opinion in Pharmacology, June 2005, Elsevier

    Prof. Dr. Ken R Bracke

  89. Matrix Metalloproteinase-12 and Cathepsin D Expression in Pulmonary Macrophages and Dendritic Cells of Cigarette Smoke-Exposed Mice

    Article • International Archives of Allergy and Immunology, January 2005, Karger Publishers

    Prof. Dr. Ken R Bracke

  90. Synthetic polyamines as vectors for gene delivery

    Article • Polymer International, January 2002, Wiley

    Prof. Dr. Ken R Bracke