All Stories

  1. Reproduction has immediate effects on female mortality, but no discernible lasting physiological impacts: A test of the disposable soma theory

    Article • Proceedings of the National Academy of Sciences, October 2024, Proceedings of the National Academy of Sciences

    Professor John Speakman

  2. A step toward precision gerontology: Lifespan effects of calorie and protein restriction are consistent with predicted impacts on entropy generation

    Article • Proceedings of the National Academy of Sciences, September 2023, Proceedings of the National Academy of Sciences

    Professor John Speakman

  3. Surviving winter on the Qinghai-Tibetan Plateau: Pikas suppress energy demands and exploit yak feces to survive winter

    Article • Proceedings of the National Academy of Sciences, July 2021, Proceedings of the National Academy of Sciences

    Professor John Speakman

  4. Late lactation in small mammals is a critically sensitive window of vulnerability to elevated ambient temperature

    Article • Proceedings of the National Academy of Sciences, September 2020, Proceedings of the National Academy of Sciences

    Professor John Speakman

  5. Low Citrate Synthase Activity Is Associated with Glucose Intolerance and Lipotoxicity

    Article • Journal of Nutrition and Metabolism, March 2019, Hindawi Publishing Corporation

    Professor John Speakman, yosra Alhindi

  6. GPR55 deficiency is associated with increased adiposity and impaired insulin signaling in peripheral metabolic tissues

    Article • The FASEB Journal, January 2019, Federation of American Societies For Experimental Biology (FASEB)

    Professor John Speakman, Professor Cherry L Wainwright, Hari Hundal

  7. The relationship between female adiposity and physical attractiveness amongst adults in rural Ranaka village, Botswana

    Article • South African Journal of Clinical Nutrition, September 2018, Taylor & Francis

    Professor John Speakman

  8. Impact of Obesity and Ozone on the Association Between Particulate Air Pollution and Cardiovascular Disease and Stroke Mortality Among US Adults

    Article • Journal of the American Heart Association, May 2018, Wolters Kluwer Health

    Professor John Speakman

  9. Association of Fast‐Food and Full‐Service Restaurant Densities With Mortality From Cardiovascular Disease and Stroke, and the Prevalence of Diabetes Mellitus

    Article • Journal of the American Heart Association, May 2018, Wolters Kluwer Health

    Professor John Speakman

  10. Why do animals store fat and what regulates the level of fat they store

    Article • Journal of Experimental Biology, March 2018, The Company of Biologists

    Professor John Speakman

  11. Peoples ratings of physical attractiveness are not related to their own level of obesity

    Article • Obesity, February 2018, Wiley

    Professor John Speakman

  12. Investment by female mice in their first lactation impacts investment in the next lactation.

    Article • Journal of Experimental Biology, January 2018, The Company of Biologists

    Professor John Speakman

  13. Regulation of body weight theories

    Article • Molecular Metabolism, January 2018, Elsevier

    Professor John Speakman

  14. Adiposity and Reproductive Cycling Status in Zoo African Elephants

    Article • Obesity, December 2017, Wiley

    Professor John Speakman

  15. Energy expenditure in professional flat jockeys using doubly labelled water during the racing season: Implications for body weight management

    Article • European Journal of Sport Science, December 2017, Taylor & Francis

    Professor John Speakman, George Wilson

  16. Effect of Probiotic Supplementation on CD4 Cell Count in HIV-Infected Patients: A Systematic Review and Meta-analysis

    Article • Journal of Dietary Supplements, November 2017, Taylor & Francis

    Professor John Speakman, Dr Sakineh Shab-Bidar

  17. On the origin of obesity: identifying the biological, environmental and cultural drivers of genetic risk among human populations

    Article • Obesity Reviews, November 2017, Wiley

    Professor John Speakman, Anila Qasim

  18. Body macronutrient composition is predicted by lipid and not protein content of the diet

    Article • Ecology and Evolution, October 2017, Wiley

    Professor John Speakman

  19. Biomarker of burden: Feather corticosterone reflects energetic expenditure and allostatic overload in captive waterfowl

    Article • Functional Ecology, October 2017, Wiley

    Professor John Speakman, Dr Graham D. Fairhurst

  20. Food environments and obesity: cannot see the fat for the restaurants?

    Article • September 2017, Cold Spring Harbor Laboratory Press

    Professor John Speakman

  21. The effects of graded levels of calorie restriction: XI. Evaluation of the main hypotheses underpinning the life extension effects of CR using the hepatic transcriptome

    Article • Aging, July 2017, Impact Journals, LLC

    Dr Cara L Green, Professor John Speakman

  22. The effects of graded levels of calorie restriction: IX. Global metabolomic screen reveals modulation of carnitines, sphingolipids and bile acids in the liver of C57BL/6 mice

    Article • Aging Cell, January 2017, Wiley

    Dr Cara L Green, ms Davina Derous, Professor John Speakman, Daniel Promislow, Luonan Chen

  23. Limits to sustained energy intake XXV: milk energy output and thermogenesis in Swiss mice lactating at thermoneutrality

    Article • Scientific Reports, August 2016, Nature

    Professor John Speakman

  24. Partitioning the variance in calorie restriction-induced weight and fat loss in outbred mice

    Article • Obesity, August 2016, Wiley

    Professor John Speakman

  25. Thyroid hormones correlate with field metabolic rate in ponies,Equus ferus caballus

    Article • Journal of Experimental Biology, June 2016, The Company of Biologists

    Professor John Speakman

  26. Limits to sustained energy intake XXIV: impact of suckling behaviour on the body temperatures of lactating female mice

    Article • Scientific Reports, May 2016, Nature

    Professor John Speakman

  27. The effects of graded levels of calorie restriction: VII. Topological rearrangement of hypothalamic aging networks

    Article • Aging, April 2016, Impact Journals, LLC

    Dr Cara L Green, ms Davina Derous, Professor John Speakman

  28. The effects of graded levels of calorie restriction: V. Impact of short term calorie and protein restriction on physical activity in the C57BL/6 mouse

    Article • Oncotarget, March 2016, Impact Journals, LLC

    Dr Cara L Green, ms Davina Derous, Professor John Speakman

  29. The effects of graded levels of calorie restriction: VI. Impact of short-term graded calorie restriction on transcriptomic responses of the hypothalamic hunger and circadian signaling pathways

    Article • Aging, February 2016, Impact Journals, LLC

    Dr Cara L Green, ms Davina Derous, Professor John Speakman

  30. Limits to sustained energy intake. XXIII. Does heat dissipation capacity limit the energy budget of lactating bank voles?

    Article • Journal of Experimental Biology, January 2016, The Company of Biologists

    Professor John Speakman

  31. Oxidative stress and life histories: unresolved issues and current needs

    Article • Ecology and Evolution, November 2015, Wiley

    Professor John Speakman

  32. The effects of graded levels of calorie restriction: IV. Non-linear change in behavioural phenotype of mice in response to short-term calorie restriction

    Article • Scientific Reports, August 2015, Nature

    Dr Cara L Green, ms Davina Derous, Professor John Speakman

  33. Evolution of Obesity

    Article • January 2015, Springer Science + Business Media

    Professor John Speakman

  34. Low resting metabolic rate is associated with greater lifespan because of a confounding effect of body fatness

    Article • AGE, December 2014, Springer Science + Business Media

    Professor John Speakman

  35. If Body Fatness is Under Physiological Regulation, Then How Come We Have an Obesity Epidemic?

    Article • Physiology, March 2014, American Physiological Society

    Professor John Speakman

  36. Effects of a specific MCHR1 antagonist (GW803430) on energy budget and glucose metabolism in diet-induced obese mice

    Article • Obesity, December 2013, Wiley

    Professor John Speakman

  37. Limits to sustained energy intake. XXI. Effect of exposing the mother, but not her pups, to a cold environment during lactation in mice

    Article • Journal of Experimental Biology, August 2013, The Company of Biologists

    Professor John Speakman

  38. Limits to sustained energy intake. XX. Body temperatures and physical activity of female mice during lactation

    Article • Journal of Experimental Biology, June 2013, The Company of Biologists

    Professor John Speakman

  39. Limits to sustained energy intake. XIX. A test of the heat dissipation limitation hypothesis in Mongolian gerbils (Meriones unguiculatus)

    Article • Journal of Experimental Biology, June 2013, The Company of Biologists

    Professor John Speakman

  40. Limits to sustained energy intake. XIV. Heritability of reproductive performance in mice

    Article • Journal of Experimental Biology, May 2013, The Company of Biologists

    Professor John Speakman

  41. Limits to sustained energy intake. XVI. Body temperature and physical activity of female mice during pregnancy

    Article • Journal of Experimental Biology, May 2013, The Company of Biologists

    Professor John Speakman

  42. Limits to sustained energy intake. XVII. Lactation performance in MF1 mice is not programmed by fetal number during pregnancy

    Article • Journal of Experimental Biology, May 2013, The Company of Biologists

    Professor John Speakman

  43. Limits to sustained energy intake. XVIII. Energy intake and reproductive output during lactation in Swiss mice raising small litters

    Article • Journal of Experimental Biology, May 2013, The Company of Biologists

    Professor John Speakman

  44. Limits to sustained energy intake. XV. Effects of wheel running on the energy budget during lactation

    Article • Journal of Experimental Biology, May 2013, The Company of Biologists

    Professor John Speakman

  45. Thyroid hormones correlate with resting metabolic rate, not daily energy expenditure, in two charadriiform seabirds

    Article • Biology Open, May 2013, The Company of Biologists

    Professor John Speakman

  46. Thyroid Hormones Correlate with Basal Metabolic Rate but Not Field Metabolic Rate in a Wild Bird Species

    Article • PLoS ONE, February 2013, PLOS

    Professor John Speakman

  47. Context-dependent correlation between resting metabolic rate and daily energy expenditure in wild chipmunks

    Article • Journal of Experimental Biology, October 2012, The Company of Biologists

    Professor John Speakman

  48. Limits to sustained energy intake. XIII. Recent progress and future perspectives

    Article • Journal of Experimental Biology, December 2010, The Company of Biologists

    Professor John Speakman

  49. Associations between over-winter survival and resting metabolic rate in juvenile North American red squirrels

    Article • Functional Ecology, February 2010, Wiley

    Professor John Speakman

  50. Limits to sustained energy intake XII: is the poor relation between resting metabolic rate and reproductive performance because resting metabolism is not a repeatable trait?

    Article • Journal of Experimental Biology, December 2009, The Company of Biologists

    Professor John Speakman

  51. Limits to sustained energy intake. XI. A test of the heat dissipation limitation hypothesis in lactating Brandt's voles (Lasiopodomys brandtii)

    Article • Journal of Experimental Biology, October 2009, The Company of Biologists

    Professor John Speakman

  52. Limits to sustained energy intake

    Article • Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology, June 2009, Elsevier

    Professor John Speakman

  53. Intra-specific variation in resting metabolic rate in MF1 mice is not associated with membrane lipid desaturation in the liver

    Article • Mechanisms of Ageing and Development, March 2008, Elsevier

    Professor John Speakman

  54. Limits to sustained energy intake. X. Effects of fur removal on reproductive performance in laboratory mice

    Article • Journal of Experimental Biology, December 2007, The Company of Biologists

    Professor John Speakman

  55. The Measurement of Resting Metabolic Rate in Preschool Children*

    Article • Obesity, August 2007, Wiley

    Professor John Speakman

  56. Intake Compensates for Resting Metabolic Rate Variation in Female C57BL/6J Mice Fed High-fat Diets*

    Article • Obesity, March 2007, Wiley

    Professor John Speakman

  57. Associations between basal metabolic rate and reproductive performance in C57BL/6J mice

    Article • Journal of Experimental Biology, January 2007, The Company of Biologists

    Professor John Speakman

  58. Additional anthropometric measures may improve the predictability of basal metabolic rate in adult subjects

    Article • European Journal of Clinical Nutrition, July 2006, Nature

    Professor John Speakman

  59. Thrifty genes for obesity and the metabolic syndrome — time to call off the search?

    Article • Diabetes and Vascular Disease Research, May 2006, SAGE Publications

    Professor John Speakman

  60. Seasonal variation in the metabolic rate and body composition of female grey seals: fat conservation prior to high-cost reproduction in a capital breeder?

    Article • Journal of Comparative Physiology B, February 2006, Springer Science + Business Media

    Professor John Speakman

  61. Expenditure freeze: the metabolic response of small mammals to cold environments

    Article • Ecology Letters, December 2005, Wiley

    Professor John Speakman

  62. Factors influencing variation in basal metabolic rate include fat-free mass, fat mass, age, and circulating thyroxine but not sex, circulating leptin, or triiodothyronine

    Article • American Journal of Clinical Nutrition, November 2005, Oxford University Press (OUP)

    Professor John Speakman

  63. Limits to sustained energy intake IX: a review of hypotheses

    Article • Journal of Comparative Physiology B, July 2005, Springer Science + Business Media

    Professor John Speakman

  64. The Functional Significance of Individual Variation in Basal Metabolic Rate

    Article • Physiological and Biochemical Zoology, November 2004, University of Chicago Press

    Professor John Speakman

  65. Measuring metabolic rate in the field: the pros and cons of the doubly labelled water and heart rate methods

    Article • Functional Ecology, April 2004, Wiley

    Professor John Speakman

  66. Limits to sustained energy intake VIII. Resting metabolic rate and organ morphology of laboratory mice lactating at thermoneutrality

    Article • Journal of Experimental Biology, December 2003, The Company of Biologists

    Professor John Speakman

  67. Physical activity and resting metabolic rate

    Article • Proceedings of The Nutrition Society, August 2003, Cambridge University Press

    Professor John Speakman

  68. Eco-physiology comes of age

    Article • Nature, August 2002, Nature

    Professor John Speakman

  69. Thermoregulation in Vertebrates: Acclimation, Acclimatization and Adaptation

    Article • April 2001, Wiley

    Professor John Speakman

  70. Body Composition Analysis of Animals

    Article • January 2001, Cambridge University Press

    Professor John Speakman

  71. Relationships between Resting Metabolic Rate and Morphology in Lactating Mice: What Tissues are the Major Contributors to Resting Metabolism?

    Article • January 2000, Springer Science + Business Media

    Professor John Speakman

  72. Effects of Body Mass and Reproduction on the Basal Metabolic Rate of Brown Long‐Eared Bats (Plecotus auritus)

    Article • Physiological and Biochemical Zoology, January 2000, University of Chicago Press

    Professor John Speakman

  73. The Cost of Living: Field Metabolic Rates of Small Mammals

    Article • January 1999, Elsevier

    Professor John Speakman

  74. Seasonal variation in the resting metabolic rate of male wood mice Apodemus sylvaticus from two contrasting habitats 15 km apart

    Article • Journal of Comparative Physiology B, April 1997, Springer Science + Business Media

    Professor John Speakman

  75. Limits to Sustained Metabolic Rate: The Link between Food Intake, Basal Metabolic Rate, and Morphology in Reproducing Mice, Mus musculus

    Article • Physiological Zoology, July 1996, University of Chicago Press

    Professor John Speakman

  76. Limits to Sustainable Metabolic Rate during Transient Exposure to Low Temperatures in Short-Tailed Field Voles (Microtus agrestis)

    Article • Physiological Zoology, September 1994, University of Chicago Press

    Professor John Speakman

  77. Central Limits to Sustainable Metabolic Rate Have No Role in Cold Acclimation of the Short-Tailed Field Vole (Microtus agrestis)

    Article • Physiological Zoology, September 1994, University of Chicago Press

    Professor John Speakman

  78. Aetiology of Human Obesity

    Article • Wiley

    Professor David Levitsky, Professor John Speakman

  79. The isotope dilution method for the evaluation of body composition

    Article • Cambridge University Press

    Professor John Speakman

  80. Genetics of Obesity

    Article • Springer Science + Business Media

    Professor John Speakman