All Stories

  1. Extracellular vesicles with ubiquitinated adenosine A 2A receptor in plasma of patients with coronary artery disease

    Article • Journal of Cellular and Molecular Medicine, August 2019, Wiley

    Jean Ruf

  2. Adenosine Plasma Level and A2A Receptor Expression in Patients With Cardiogenic Shock

    Article • Critical Care Medicine, September 2018, Wolters Kluwer Health

    Jean Ruf

  3. Uric acid levels are associated with endothelial dysfunction and severity of coronary atherosclerosis during a first episode of acute coronary syndrome

    Article • Purinergic Signalling, April 2018, Springer Science + Business Media

    Jean Ruf

  4. Specific Pharmacological Profile of A 2A Adenosine Receptor Predicts Reduced Fractional Flow Reserve in Patients With Suspected Coronary Artery Disease

    Article • Journal of the American Heart Association, April 2018, Wolters Kluwer Health

    Jean Ruf

  5. Towards Addressing the Body Electrolyte Environment via Sweat Analysis:Pilocarpine Iontophoresis Supports Assessment of Plasma Potassium Concentration

    Article • Scientific Reports, September 2017, Springer Science + Business Media

    Jean Ruf

  6. Thyroid peroxidase (TPO) expressed in thyroid and breast tissues shows similar antigenic properties

    Article • PLoS ONE, June 2017, PLOS

    Jean Ruf

  7. Expressions of adenosine A2A receptors in coronary arteries and peripheral blood mononuclear cells are correlated in coronary artery disease patients

    Article • International Journal of Cardiology, March 2017, Elsevier

    Jean Ruf

  8. Pathophysiological and diagnostic implications of cardiac biomarkers and antidiuretic hormone release in distinguishing immersion pulmonary edema from decompression sickness

    Article • Medicine, June 2016, Wolters Kluwer Health

    Jean Ruf

  9. High homocysteine levels prevent via H 2 S the CoCl 2 ‐induced alteration of lymphocyte viability

    Article • Journal of Cellular and Molecular Medicine, April 2016, Wiley

    Jean Ruf

  10. Ticagrelor Improves Peripheral Arterial Function in Acute Coronary Syndrome Patients

    Article • Journal of the American College of Cardiology, April 2016, Elsevier

    Jean Ruf

  11. Adenosine plasma level correlates with homocysteine and uric acid concentrations in patients with coronary artery disease

    Article • Canadian Journal of Physiology and Pharmacology, March 2016, Canadian Science Publishing

    Jean Ruf

  12. Spare Adenosine A2a Receptors Are Associated with Positive Exercise Stress Test in Coronary Artery Disease

    Article • Molecular Medicine, January 2016, Springer Science + Business Media

    Jean Ruf

  13. Effect of hyperoxic and hyperbaric conditions on the adenosinergic pathway and CD26 expression in rat

    Article • Journal of Applied Physiology, July 2015, American Physiological Society

    Jean Ruf

  14. Adenosine and Clinical Forms of Neurally-Mediated Syncope

    Article • Journal of the American College of Cardiology, July 2015, Elsevier

    Jean Ruf

  15. Low basal expression of A2A adenosine receptors and increase in adenosine plasma concentration are associated with positive exercise stress testing

    Article • International Journal of Cardiology, February 2015, Elsevier

    Dr Alain Boussuges, Jean Ruf

  16. NF-κB enhances hypoxia-driven T-cell immunosuppression via upregulation of adenosine A2A receptors

    Article • Cellular Signalling, May 2014, Elsevier

    Jean Ruf

  17. Syncope Without Prodromes in Patients With Normal Heart and Normal Electrocardiogram

    Article • Journal of the American College of Cardiology, September 2013, Elsevier

    Jean Ruf

  18. Mononuclear cell adenosine deaminase and CD26/dipeptidylpeptidase-IV activities are sensitive markers of reperfusion during percutaneous transluminal angioplasty

    Article • International Journal of Cardiology, June 2013, Elsevier

    Dr Alain Boussuges, Jean Ruf

  19. A2A adenosine receptor function in patients with vasovagal syncope

    Article • EP Europace, April 2013, European Society of Cardiology

    Jean Ruf

  20. SKCa Channels Blockage Increases the Expression of Adenosine A2A Receptor in Jurkat Human T Cells

    Article • BioResearch Open Access, April 2013, Mary Ann Liebert Inc

    Jean Ruf

  21. Search for adenosine A2A spare receptors on peripheral human lymphocytes

    Article • FEBS Open Bio, November 2012, Wiley

    Jean Ruf

  22. Adenosine plasma level and A2Aadenosine receptor expression: correlation with laboratory tests in patients with neurally mediated syncope

    Article • Heart, May 2012, BMJ

    Jean Ruf

  23. High cell surface CD26-associated activities and low plasma adenosine concentration in fibromyalgia

    Article • Annals of the Rheumatic Diseases, April 2012, BMJ

    Jean Ruf

  24. Fall in oxygen tension of culture medium stimulates the adenosinergic signalling of a human T cell line

    Article • Purinergic Signalling, February 2012, Springer Science + Business Media

    Jean Ruf

  25. Cell biology of H2O2 generation in the thyroid: Investigation of the control of dual oxidases (DUOX) activity in intact ex vivo thyroid tissue and cell lines

    Article • Molecular and Cellular Endocrinology, August 2011, Elsevier

    Jean Ruf

  26. Syncope Due to Idiopathic Paroxysmal Atrioventricular Block

    Article • Journal of the American College of Cardiology, July 2011, Elsevier

    Jean Ruf

  27. Acute Pulmonary Embolism Decreases Adenosine Plasma Levels in Anesthetized Pigs

    Article • ISRN Cardiology, January 2011, Hindawi Publishing Corporation

    Jean Ruf

  28. Intracerebroventricular injection of an agonist-like monoclonal antibody to adenosine A2A receptor has antinociceptive effects in mice

    Article • Journal of Neuroimmunology, January 2011, Elsevier

    Jean Ruf

  29. Monoclonal antibody–assisted stimulation of adenosine A2A receptors induces simultaneous downregulation of CXCR4 and CCR5 on CD4+ T-cells

    Article • Human Immunology, November 2010, Elsevier

    Jean Ruf

  30. Expeditious synthesis and biological evaluation of new C-6 1,2,3-triazole adenosine derivatives A1 receptor antagonists or agonists

    Article • Organic & Biomolecular Chemistry, January 2010, Royal Society of Chemistry

    Gaelle Chouraqui, Jean Ruf

  31. Association of Duoxes with Thyroid Peroxidase and Its Regulation in Thyrocytes

    Article • The Journal of Clinical Endocrinology & Metabolism, January 2010, Endocrine Society

    Jean Ruf

  32. Design, synthesis and biological evaluation of a bivalent μ opiate and adenosine A1 receptor antagonist

    Article • Bioorganic & Medicinal Chemistry Letters, December 2009, Elsevier

    Jean Ruf

  33. Role of caveolin-1 in thyroid phenotype, cell homeostasis, and hormone synthesis: in vivo study of caveolin-1 knockout mice

    Article • AJP Endocrinology and Metabolism, August 2009, American Physiological Society

    Jean Ruf

  34. Production of an agonist-like monoclonal antibody to the human A2A receptor of adenosine for clinical use

    Article • Molecular Immunology, January 2009, Elsevier

    Jean Ruf

  35. Significance of thyroglobulin antibodies cross-reactive with thyroperoxidase (TGPO antibodies) in individual patients and immunized mice

    Article • Clinical & Experimental Immunology, June 2008, Wiley

    Jean Ruf

  36. Anti-thyroperoxidase antibodies from patients with Hashimoto's encephalopathy bind to cerebellar astrocytes

    Article • Journal of Neuroimmunology, December 2007, Elsevier

    Jean Ruf

  37. Release of Markers of Myocardial Damage Evaluated in the Coronary Sinus During Cardiac Surgery

    Article • Journal of Investigative Medicine, May 2007, BMJ

    Jean Ruf

  38. Reciprocal Negative Regulation between Thyrotropin/3′,5′-Cyclic Adenosine Monophosphate-Mediated Proliferation and Caveolin-1 Expression in Human and Murine Thyrocytes

    Article • Molecular Endocrinology, April 2007, Endocrine Society

    Jean Ruf

  39. Influence of haemodialysis and left ventricular failure on peripheral A2A adenosine receptor expression

    Article • Nephrology Dialysis Transplantation, January 2007, Oxford University Press (OUP)

    Jean Ruf

  40. Relationship between A2A Adenosine Receptor Expression and Intradialytic Hypotension during Hemodialysis

    Article • Journal of Investigative Medicine, December 2006, BMJ

    Jean Ruf

  41. Structural and functional aspects of thyroid peroxidase

    Article • Archives of Biochemistry and Biophysics, January 2006, Elsevier

    Jean Ruf

  42. Thyroglobulin Autoantibodies in Iodized Subjects: Relationship Between Epitope Specificities and Longitudinal Antibody Activity

    Article • Thyroid, September 2005, Mary Ann Liebert Inc

    Jean Ruf

  43. Human Autoantibodies Modulate the T Cell Epitope Repertoire but Fail to Unmask a Pathogenic Cryptic Epitope

    Article • The Journal of Immunology, December 2004, The American Association of Immunologists

    Jean Ruf

  44. An in vitro model based on cell monolayers grown on the underside of large- pore filters in bicameral chambers for studying thyrocyte-lymphocyte interactions

    Article • AJP Cell Physiology, December 2004, American Physiological Society

    Jean Ruf

  45. Antigenicity and immunogenicity of the C-terminal peptide of human thyroglobulin

    Article • Peptides, June 2004, Elsevier

    Jean Ruf

  46. Directed Mutagenesis in Region 713-720 of Human Thyroperoxidase Assigns713KFPED717Residues as Being Involved in the B Domain of the Discontinuous Immunodominant Region Recognized by Human Autoantibodies

    Article • Journal of Biological Chemistry, May 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Jean Ruf

  47. Complement Activation by Direct C4 Binding to Thyroperoxidase in Hashimoto’s Thyroiditis

    Article • Endocrinology, December 2003, Endocrine Society

    Jean Ruf

  48. Thyroglobulin epitope recognition in a post iodine-supplemented Sri Lankan population

    Article • Clinical Endocrinology, August 2003, Wiley

    Jean Ruf

  49. Evidence that the Complement Control Protein-Epidermal Growth Factor-Like Domain of Thyroid Peroxidase Lies on the Fringe of the Immunodominant Region Recognized by Autoantibodies

    Article • Thyroid, December 2002, Mary Ann Liebert Inc

    Jean Ruf

  50. Androgen-dependent expression of FcgammaRIIB2 by thyrocytes from patients with autoimmune Graves' disease: a possible molecular clue for sex dependence of autoimmune disease

    Article • The FASEB Journal, July 2002, Federation of American Societies For Experimental Biology (FASEB)

    Jean Ruf

  51. Analysis of a conformational B cell epitope of human thyroid peroxidase: identification of a tyrosine residue at a strategic location for immunodominance

    Article • International Immunology, April 2002, Oxford University Press (OUP)

    Jean Ruf

  52. Hydrogen peroxide-induced production of a 40 kDa immunoreactive thyroglobulin fragment in human thyroid cells: the onset of thyroid autoimmunity?

    Article • Biochemical Journal, December 2001, Portland Press Ltd.

    Professor Ulla Feldt-Rasmussen, Jean Ruf

  53. Production of Immunoreactive Thyroglobulin C-Terminal Fragments during Thyroid Hormone Synthesis

    Article • Endocrinology, July 2000, Endocrine Society

    Jean Ruf

  54. Molecular Model, Calcium Sensitivity, and Disease Specificity of a Conformational Thyroperoxidase B-cell Epitope

    Article • Journal of Biological Chemistry, December 1999, American Society for Biochemistry & Molecular Biology (ASBMB)

    Jean Ruf

  55. Multicenter study on TGPO autoantibody prevalence in various thyroid and non-thyroid diseases; relationships with thyroglobulin and thyroperoxidase autoantibody parameters

    Article • December 1999

    Professor Ulla Feldt-Rasmussen, Jean Ruf

  56. Thyroglobulin monoclonal antibody cross-reacting with thyroperoxidase induces in syngeneic mice anti-idiotypic monoclonal antibodies with dual autoantigen binding properties. The intertope hypothesis

    Article • European Journal of Immunology, May 1999, Wiley

    Jean Ruf

  57. Comparative Mapping of Cloned Human and Murine Antithyroglobulin Antibodies: Recognition by Human Antibodies of an Immunodominant Region

    Article • Thyroid, August 1998, Mary Ann Liebert Inc

    Jean Ruf

  58. A Conformational B-cell Epitope on the C-terminal End of the Extracellular Part of Human Thyroid Peroxidase

    Article • Journal of Biological Chemistry, April 1998, American Society for Biochemistry & Molecular Biology (ASBMB)

    Jean Ruf

  59. Idiotypic Study of a Bispecific Thyroglobulin and Thyroperoxidase Monoclonal Antibody

    Article • Journal of Autoimmunity, October 1996, Elsevier

    Jean Ruf

  60. Antibody-dependent cell-mediated cytotoxicity in autoimmune thyroid disease: relationship to antithyroperoxidase antibodies

    Article • The Journal of Clinical Endocrinology & Metabolism, July 1996, Endocrine Society

    Jean Ruf

  61. Majority of Thyroid Peroxidase Autoantibodies in Patients with Autoimmune Thyroid Disease are Directed to a Single TPO Domain

    Article • Autoimmunity, January 1996, Taylor & Francis

    Jean Ruf

  62. The molecular recognition theory applied to bispecific antibodies …

    Article • Nature Reports Stem Cells, December 1995, Springer Science + Business Media

    Jean Ruf

  63. Identification of the thyroid Na+/I− cotransporter as a potential autoantigen in thyroid autoimmune disease

    Article • European Journal of Endocrinology, April 1995, Bioscientifica

    Jean Ruf

  64. Bispecific thyroglobulin and thyroperoxidase autoantibodies in patients with various thyroid and autoimmune diseases

    Article • The Journal of Clinical Endocrinology & Metabolism, November 1994, Endocrine Society

    Jean Ruf

  65. Overexpression of the extracellular domain of the thyrotrophin receptor in bacteria; production of thyrotrophin-binding inhibiting immunoglobulins

    Article • Journal of Molecular Endocrinology, August 1994, Bioscientifica

    Jean Ruf

  66. Induction of Thyrotropin Receptor (TSH-R) Autoantibodies and Thyroiditis in Mice Immunized with the Recombinant TSH-R

    Article • Biochemical and Biophysical Research Communications, March 1994, Elsevier

    Jean Ruf

  67. Autoantibodies and Monoclonal Antibodies Directed to an Immunodominant Antigenic Region of Thyroglobulin Interact with Thyroperoxidase Through an Interspecies Idiotype

    Article • Autoimmunity, January 1994, Taylor & Francis

    Jean Ruf

  68. Thyroglobulin in medullary thyroid carcinoma: Immunohistochemical study with polyclonal and monoclonal antibodies

    Article • Human Pathology, March 1993, Elsevier

    Jean Ruf

  69. Tyrosine iodination and iodotyrosyl coupling of the N-terminal thyroid hormone forming site of human thyroglobulin modulate its binding to auto- and monoclonal antibodies

    Article • Molecular and Cellular Endocrinology, October 1992, Elsevier

    Jean Ruf

  70. Sequence of the complete cDNA and the 5′ structure of the human sucrase-isomaltase gene. Possible homology with a yeast glucoamylase

    Article • Biochemical Journal, August 1992, Portland Press Ltd.

    Jean Ruf

  71. Effects of deglycosylation of human thyroperoxidase on its enzymatic activity and immunoreactivity

    Article • Journal of Endocrinology, February 1992, Bioscientifica

    Jean Ruf

  72. Determination at the Molecular Level of a B-Cell Epitope on Thyroid Peroxidase Likely to Be Associated with Autoimmune Thyroid Disease*

    Article • The Journal of Clinical Endocrinology & Metabolism, October 1991, Endocrine Society

    Jean Ruf

  73. Immunohistochemical study of thyroid peroxidase in normal, hyperplastic, and neoplastic human thyroid tissues

    Article • Cancer, June 1991, Wiley

    Jean Ruf

  74. Monoclonal Antiidiotypic Antibodies Interact with the 93 Kilodalton Thyrotropin Receptor and Exhibit Heterogeneous Biological Activities

    Article • Endocrinology, March 1991, Endocrine Society

    Jean Ruf

  75. Prevalence of Autoantibodies to Thyroperoxidase in Patients with Various Thyroid and Autoimmune Diseases

    Article • Autoimmunity, January 1991, Taylor & Francis

    Jean Ruf

  76. Relationship between Immunological Structure and Biochemical Properties of Human Thyroid Peroxidase

    Article • Endocrinology, September 1989, Endocrine Society

    Jean Ruf

  77. Antibodies to Human Thyroid Peroxidase in Autoimmune Thyroid Disease: Studies with a Cloned Recombinant Complementary Deoxyribonucleic Acid Epitope*

    Article • The Journal of Clinical Endocrinology & Metabolism, June 1989, Endocrine Society

    Jean Ruf

  78. Thyroglobulin structure and function: recent advances

    Article • Biochimie, February 1989, Elsevier

    Jean Ruf

  79. Cytotoxic Assay of Circulating Thyroid Peroxidase Antibodies

    Article • Autoimmunity, January 1989, Taylor & Francis

    Jean Ruf

  80. Immunocytochemical Study of Localization and Traffic of Thyroid Peroxidase/Microsomal Antigen

    Article • Autoimmunity, January 1989, Taylor & Francis

    Jean Ruf

  81. Comparison of Serum Thyroid Microsomal and Thyroid Peroxidase Autoantibodies in Thyroid Diseases*

    Article • The Journal of Clinical Endocrinology & Metabolism, November 1987, Endocrine Society

    Jean Ruf

  82. Immunohistochemical study of thyroglobulin in thyroid carcinomas with monoclonal antibodies

    Article • Cancer, February 1987, Wiley

    Jean Ruf

  83. Idiotypic analysis of five xenogeneic antisera to anti-human thyroglobulin monoclonal antibodies

    Article • Immunology Letters, August 1986, Elsevier

    Jean Ruf

  84. Purification of the human thyroid peroxidase and its identification as the microsomal antigen involved in autoimmune thyroid diseases

    Article • FEBS Letters, October 1985, Wiley

    Jean Ruf

  85. Cell membrane coating with glutaraldehyde: Application to a versatile solid-phase assay for thyroid membrane proteins and molecules interacting with thyroid membranes

    Article • Analytical Biochemistry, August 1985, Elsevier

    Jean Ruf

  86. Various expressions of a unique anti-human thyroglobulin antibody repertoire in normal state and autoimmune disease

    Article • European Journal of Immunology, January 1985, Wiley

    Jean Ruf

  87. Auto-and heteroantibodies against human thyroglobulin present the same heterogeneity and fine specificities

    Article • Journal of Steroid Biochemistry, June 1984, Elsevier

    Jean Ruf

  88. Specificity of monoclonal antibodies against human thyroglobulin; comparison with autoimmune antibodies.

    Article • The EMBO Journal, October 1983, Wiley

    Jean Ruf

  89. Structural bases for public idiotypic specificities of monoclonal antibodies directed against poly(Glu60Ala30Tyr10) and poly(Glu60Ala40) random copolymers.

    Article • Proceedings of the National Academy of Sciences, May 1983, Proceedings of the National Academy of Sciences

    Jean Ruf