All Stories

  1. Sequence-dependent scale for translocon-mediated insertion of interfacial helices in membranes

    Article • Science Advances, February 2025, American Association for the Advancement of Science

    PhD Ismael Mingarro

  2. Experimental and computational approaches for membrane protein insertion and topology determination

    Article • Methods, June 2024, Elsevier

    PhD Ismael Mingarro

  3. Cetylpyridinium chloride and chlorhexidine show antiviral activity against Influenza A virus and Respiratory Syncytial virus in vitro

    Article • PLOS One, February 2024, PLOS

    PhD Ismael Mingarro

  4. Identification of small molecules capable of enhancing viral membrane fusion

    Article • Virology Journal, May 2023, Springer Science + Business Media

    PhD Ismael Mingarro

  5. Computational design of cell death regulators that target protein interactions inside the membrane.

    Article • Proceedings of the National Academy of Sciences, March 2023, Proceedings of the National Academy of Sciences

    Gerard Duart, PhD Ismael Mingarro

  6. Intra-Helical Salt Bridge Contribution to Membrane Protein Insertion

    Article • Journal of Molecular Biology, March 2022, Elsevier

    PhD Ismael Mingarro

  7. Cetylpyridinium chloride promotes disaggregation of SARS-CoV-2 virus-like particles

    Article • Journal of Oral Microbiology, January 2022, Taylor & Francis

    PhD Ismael Mingarro

  8. Methodological approaches for the analysis of transmembrane domain interactions: A systematic review

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, December 2021, Elsevier

    PhD Ismael Mingarro

  9. Folding and Insertion of Transmembrane Helices at the ER

    Article • International Journal of Molecular Sciences, November 2021, MDPI AG

    PhD Ismael Mingarro

  10. Conformational Clamping by a Membrane Ligand Activates the EphA2 Receptor

    Article • Journal of Molecular Biology, September 2021, Elsevier

    PhD Ismael Mingarro

  11. The SARS-CoV-2 envelope (E) protein has evolved towards membrane topology robustness

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, July 2021, Elsevier

    PhD Ismael Mingarro

  12. Role of pulmonary surfactant protein Sp-C dimerization on membrane fragmentation: An emergent mechanism involved in lung defense and homeostasis

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, June 2021, Elsevier

    PhD Ismael Mingarro

  13. The importance of transmembrane domain interactions in the viral control of apoptosis

    Article • Molecular & Cellular Oncology, May 2021, Taylor & Francis

    PhD Ismael Mingarro

  14. Conformational clamping by a membrane ligand activates the EphA2 receptor

    Article • April 2021, Cold Spring Harbor Laboratory Press

    PhD Ismael Mingarro

  15. Author Correction: Viral Bcl2s’ transmembrane domain interact with host Bcl2 proteins to control cellular apoptosis

    Article • Nature Communications, April 2021, Springer Science + Business Media

    PhD Ismael Mingarro

  16. Intra-helical salt bridge contribution to membrane protein insertion

    Article • February 2021, Cold Spring Harbor Laboratory Press

    PhD Ismael Mingarro

  17. Controllable membrane remodeling by a modified fragment of the apoptotic protein Bax

    Article • Faraday Discussions, January 2021, Royal Society of Chemistry

    PhD Ismael Mingarro

  18. Viral Bcl2s’ transmembrane domain interact with host Bcl2 proteins to control cellular apoptosis

    Article • Nature Communications, November 2020, Springer Science + Business Media

    PhD Ismael Mingarro

  19. Mcl-1 and Bok transmembrane domains: Unexpected players in the modulation of apoptosis

    Article • Proceedings of the National Academy of Sciences, October 2020, Proceedings of the National Academy of Sciences

    PhD Ismael Mingarro

  20. SARS-CoV-2 envelope protein topology in eukaryotic membranes

    Article • Open Biology, September 2020, Royal Society Publishing

    PhD Ismael Mingarro

  21. SARS-CoV-2 envelope protein topology in eukaryotic membranes

    Article • May 2020, Cold Spring Harbor Laboratory Press

    PhD Ismael Mingarro

  22. Insertion of Bacteriorhodopsin Helix C Variants into Biological Membranes

    Article • ACS Omega, December 2019, American Chemical Society (ACS)

    PhD Ismael Mingarro

  23. A Bimolecular Multicellular Complementation System for the Detection of Syncytium Formation: A New Methodology for the Identification of Nipah Virus Entry Inhibitors

    Article • Viruses, March 2019, MDPI AG

    PhD Ismael Mingarro

  24. A Bimolecular Multicelular complementation system for the detection of syncytium formation: A new methodology for the identification of entry inhibitors

    Article • January 2019, Cold Spring Harbor Laboratory Press

    PhD Ismael Mingarro

  25. Transmembrane but not soluble helices fold inside the ribosome tunnel

    Article • Nature Communications, December 2018, Springer Science + Business Media

    PhD Ismael Mingarro

  26. Characterization of the inner membrane protein BB0173 from Borrelia burgdorferi

    Article • BMC Microbiology, November 2017, Springer Science + Business Media

    PhD Ismael Mingarro

  27. Effect of hydrophobic matching on transmembrane helix packing

    Article • Cell Stress, November 2017, Shared Science Publishers OG

    PhD Ismael Mingarro

  28. Proteomic composition of Nipah virus -like particles

    Article • Journal of Proteomics, October 2017, Elsevier

    PhD Ismael Mingarro

  29. Exploring the Human-Nipah Virus Protein-Protein Interactome

    Article • Journal of Virology, September 2017, ASM Journals

    PhD Ismael Mingarro, Gerard Duart

  30. N -Linked Glycosylation of the p24 Family Protein p24δ5 Modulates Retrograde Golgi-to-ER Transport of K/HDEL Ligands in Arabidopsis

    Article • Molecular Plant, August 2017, Elsevier

    PhD Ismael Mingarro

  31. Membrane insertion and topology of the translocon-associated protein (TRAP) gamma subunit

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, May 2017, Elsevier

    PhD Ismael Mingarro

  32. Role of Bcl-2 transmembrane segments in mitochondrial apoptosis

    Article • Proceedings of the National Academy of Sciences, December 2016, Proceedings of the National Academy of Sciences

    PhD Ismael Mingarro

  33. NMR Investigation of Structures of G-protein Coupled Receptor Folding Intermediates

    Article • Journal of Biological Chemistry, November 2016, American Society for Biochemistry & Molecular Biology (ASBMB)

    PhD Ismael Mingarro

  34. The C-terminal Domains of Apoptotic BH3-only Proteins Mediate Their Insertion into Distinct Biological Membranes

    Article • Journal of Biological Chemistry, October 2016, American Society for Biochemistry & Molecular Biology (ASBMB)

    PhD Ismael Mingarro

  35. How short a transmembrane segment could be?

    Article • Scientific Reports, March 2016, Nature

    PhD Ismael Mingarro

  36. The ER-Membrane Transport System Is Critical for Intercellular Trafficking of the NSm Movement Protein and Tomato Spotted Wilt Tospovirus

    Article • PLoS Pathogens, February 2016, PLOS

    PhD Ismael Mingarro

  37. Human Peroxin PEX3 Is Co‐translationally Integrated into the ER and Exits the ER in Budding Vesicles

    Article • Traffic, December 2015, Wiley

    PhD Ismael Mingarro

  38. Molecular and topological membrane folding determinants of transient receptor potential vanilloid 2 channel

    Article • Biochemical and Biophysical Research Communications, July 2015, Elsevier

    PhD Ismael Mingarro

  39. Insertion and assembly of viroporins within biological membranes

    Article • Viruses, June 2015, MDPI AG

    PhD Ismael Mingarro

  40. Peptides Derived from the Transmembrane Domain of Bcl-2 Proteins as Potential Mitochondrial Priming Tools

    Article • ACS Chemical Biology, August 2014, American Chemical Society (ACS)

    PhD Ismael Mingarro

  41. A transmembrane serine residue in the Rot1 protein is essential for yeast cell viability

    Article • Biochemical Journal, March 2014, Portland Press Ltd.

    PhD Ismael Mingarro

  42. Membrane integration of polytopic (multispanning) membrane proteins

    Article • Biological Chemistry, January 2014, De Gruyter

    PhD Ismael Mingarro

  43. TMV movement protein is not a transmembrane protein

    Article • Journal of Virology, December 2013, ASM Journals

    PhD Ismael Mingarro

  44. The genome sequencing of an albino Western lowland gorilla reveals inbreeding in the wild

    Article • BMC Genomics, May 2013, Springer Science + Business Media

    PhD Ismael Mingarro, Professor Jaume Bertranpetit

  45. BB0172, a Borrelia burgdorferi Outer Membrane Protein That Binds Integrin  3 1

    Article • Journal of Bacteriology, May 2013, ASM Journals

    PhD Ismael Mingarro

  46. Charge Pair Interactions in Transmembrane Helices and Turn Propensity of the Connecting Sequence Promote Helical Hairpin Insertion

    Article • Journal of Molecular Biology, February 2013, Elsevier

    PhD Ismael Mingarro

  47. Membrane-Perturbing Activities of KL4-Related Surfactant Peptides

    Article • Biophysical Journal, January 2013, Elsevier

    PhD Ismael Mingarro

  48. Polar/Ionizable Residues in Transmembrane Segments: Effects on Helix-Helix Packing

    Article • PLOS One, September 2012, PLOS

    PhD Ismael Mingarro

  49. Structure-based statistical analysis of transmembrane helices

    Article • European Biophysics Journal, May 2012, Springer Science + Business Media

    PhD Ismael Mingarro

  50. Interfacial Behavior of Recombinant Forms of Human Pulmonary Surfactant Protein SP-C

    Article • Langmuir, May 2012, American Chemical Society (ACS)

    PhD Ismael Mingarro

  51. Biophysical Characterization of TRPV2 Ion Channel

    Article • Biophysical Journal, January 2012, Elsevier

    PhD Ismael Mingarro, Rachelle Gaudet

  52. Effects of KL4-Type Peptides on the Surface Activity and Stability of Pulmonary Surfactant Films as Evaluated in the Captive Bubble Surfactometer

    Article • Biophysical Journal, January 2012, Elsevier

    PhD Ismael Mingarro

  53. Membrane Integration of Poliovirus 2B Viroporin

    Article • Journal of Virology, August 2011, ASM Journals

    PhD Ismael Mingarro

  54. Review on membrane protein insertion and assembly

    Article • FEBS Journal, June 2011, Wiley

    PhD Ismael Mingarro

  55. Membrane Insertion and Topology of the Translocating Chain-Associating Membrane Protein (TRAM)

    Article • Journal of Molecular Biology, March 2011, Elsevier

    PhD Ismael Mingarro

  56. N‐glycosylation efficiency is determined by the distance to the C‐terminus and the amino acid preceding an Asn‐Ser‐Thr sequon

    Article • Protein Science, December 2010, Wiley

    PhD Ismael Mingarro

  57. Palmitoylation of Pulmonary Surfactant Protein SP-C Is Critical for Its Functional Cooperation with SP-B to Sustain Compression/Expansion Dynamics in Cholesterol-Containing Surfactant Films

    Article • Biophysical Journal, November 2010, Elsevier

    PhD Ismael Mingarro

  58. Membrane Insertion and Biogenesis of the Turnip Crinkle Virus p9 Movement Protein

    Article • Journal of Virology, March 2010, ASM Journals

    PhD Ismael Mingarro

  59. Membrane topology of gp41 and amyloid precursor protein: Interfering transmembrane interactions as potential targets for HIV and Alzheimer treatment

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, October 2009, Elsevier

    PhD Ismael Mingarro

  60. Activation of the p75 Neurotrophin Receptor through Conformational Rearrangement of Disulphide-Linked Receptor Dimers

    Article • Neuron, April 2009, Elsevier

    PhD Ismael Mingarro

  61. Plant Virus Cell-to-Cell Movement Is Not Dependent on the Transmembrane Disposition of Its Movement Protein

    Article • Journal of Virology, March 2009, ASM Journals

    PhD Ismael Mingarro

  62. Viral Membrane Protein Topology Is Dictated by Multiple Determinants in Its Sequence

    Article • Journal of Molecular Biology, March 2009, Elsevier

    PhD Ismael Mingarro

  63. The Surfactant Peptide KL4 Sequence Is Inserted with a Transmembrane Orientation into the Endoplasmic Reticulum Membrane

    Article • Biophysical Journal, September 2008, Elsevier

    PhD Ismael Mingarro

  64. Synthetic Pulmonary Surfactant Preparations: New Developments and Future Trends

    Article • Current Medicinal Chemistry, February 2008, Bentham Science Publishers

    PhD Ismael Mingarro

  65. Membrane insertion and topology of the p7B movement protein of Melon Necrotic Spot Virus (MNSV)

    Article • Virology, October 2007, Elsevier

    PhD Ismael Mingarro

  66. Sec61α and TRAM are Sequentially Adjacent to a Nascent Viral Membrane Protein during its ER Integration

    Article • Journal of Molecular Biology, February 2007, Elsevier

    PhD Ismael Mingarro

  67. RNA-binding properties and membrane insertion of Melon necrotic spot virus (MNSV) double gene block movement proteins

    Article • Virology, December 2006, Elsevier

    PhD Ismael Mingarro

  68. Hexapeptides that interfere with HIV‐1 fusion peptide activity in liposomes block GP41‐mediated membrane fusion

    Article • FEBS Letters, April 2006, Wiley

    PhD Ismael Mingarro

  69. Production and characterisation of recombinant forms of human pulmonary surfactant protein C (SP-C): Structure and surface activity

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, April 2006, Elsevier

    PhD Ismael Mingarro, Juan Calvete

  70. Peptides corresponding to helices 5 and 6 of Bax can independently form large lipid pores

    Article • FEBS Journal, February 2006, Wiley

    PhD Ismael Mingarro

  71. Small molecule inhibitors of Apaf-1-related caspase- 3/-9 activation that control mitochondrial-dependent apoptosis

    Article • Cell Death and Differentiation, December 2005, Springer Science + Business Media

    PhD Ismael Mingarro

  72. Transient Structural Ordering of the RNA‐Binding Domain of Carnation Mottle Virus p7 Movement Protein Modulates Nucleic Acid Binding

    Article • ChemBioChem, August 2005, Wiley

    PhD Ismael Mingarro

  73. Mutational analysis of the RNA-binding domain of the Prunus necrotic ringspot virus (PNRSV) movement protein reveals its requirement for cell-to-cell movement

    Article • Virology, August 2005, Elsevier

    PhD Ismael Mingarro

  74. Peptides Derived from Apoptotic Bax and Bid Reproduce the Poration Activity of the Parent Full-Length Proteins

    Article • Biophysical Journal, June 2005, Elsevier

    PhD Ismael Mingarro

  75. Plant viral movement protein insertion into biological membranes

    Article • Journal of Biological Chemistry, May 2005, American Society for Biochemistry & Molecular Biology (ASBMB)

    PhD Ismael Mingarro

  76. Influence of hydrophobic matching on association of model transmembrane fragments containing a minimised glycophorin A dimerisation motif

    Article • FEBS Letters, February 2005, Wiley

    PhD Ismael Mingarro

  77. Identification from a Positional Scanning Peptoid Library of in Vivo Active Compounds That Neutralize Bacterial Endotoxins

    Article • Journal of Medicinal Chemistry, February 2005, American Chemical Society (ACS)

    PhD Ismael Mingarro

  78. Membrane-Insertion Fragments of Bcl-xL, Bax, and Bid

    Article • Biochemistry, July 2004, American Chemical Society (ACS)

    PhD Ismael Mingarro

  79. Roles of a conserved proline in the internal fusion peptide of Ebola glycoprotein

    Article • FEBS Letters, June 2004, Wiley

    PhD Ismael Mingarro

  80. Helix-Helix Packing Between Transmembrane Fragments

    Article • January 2004, Springer Science + Business Media

    PhD Ismael Mingarro

  81. Influence of Proline Residues in Transmembrane Helix Packing

    Article • Journal of Molecular Biology, January 2004, Elsevier

    PhD Ismael Mingarro

  82. Article • BMC Structural Biology, January 2004, Springer Science + Business Media

    PhD Ismael Mingarro

  83. Article • BMC Structural Biology, January 2004, Springer Science + Business Media

    PhD Ismael Mingarro

  84. The Structural Plasticity of the C Terminus of p21Cip1 is a Determinant for Target Protein Recognition

    Article • ChemBioChem, September 2003, Wiley

    PhD Ismael Mingarro

  85. Calcium‐dependent conformational changes of membrane‐bound Ebola fusion peptide drive vesicle fusion

    Article • FEBS Letters, December 2002, Wiley

    PhD Ismael Mingarro

  86. Peptides in apoptosis research

    Article • Journal of Peptide Science, September 2002, Wiley

    PhD Ismael Mingarro

  87. Insertion and Topology of a Plant Viral Movement Protein in the Endoplasmic Reticulum Membrane

    Article • Journal of Biological Chemistry, April 2002, American Society for Biochemistry & Molecular Biology (ASBMB)

    PhD Ismael Mingarro

  88. Distant Downstream Sequence Determinants Can Control N-tail Translocation during Protein Insertion into the Endoplasmic Reticulum Membrane

    Article • Journal of Biological Chemistry, February 2000, American Society for Biochemistry & Molecular Biology (ASBMB)

    PhD Ismael Mingarro

  89. Influence of the C‐terminus of the glycophorin A transmembrane fragment on the dimerization process

    Article • Protein Science, January 2000, Wiley

    PhD Ismael Mingarro

  90. Article • BMC Cell Biology, January 2000, Springer Science + Business Media

    PhD Ismael Mingarro

  91. Article • Molecular Diversity, January 2000, Springer Science + Business Media

    PhD Ismael Mingarro

  92. Helix-helix packing in a membrane-like environment

    Article • Journal of Molecular Biology, October 1997, Elsevier

    PhD Ismael Mingarro

  93. Membrane-protein engineering

    Article • Trends in Biotechnology, October 1997, Elsevier

    PhD Ismael Mingarro

  94. Ala‐insertion scanning mutagenesis of the glycophorin a transmembrane helix: A rapid way to map helix‐helix interactions in integral membrane proteins

    Article • Protein Science, July 1996, Wiley

    PhD Ismael Mingarro

  95. Interfacial Activation-Based Molecular Bioimprinting: Towards a More Rational Use of Lipolytic Enzymes in Nonaqueous Media

    Article • January 1996, Springer Science + Business Media

    PhD Ismael Mingarro

  96. Trapping of Different Lipase Conformers in Water-Restricted Environments

    Article • Biochemistry, January 1996, American Chemical Society (ACS)

    PhD Ismael Mingarro

  97. Activation of bee venom phospholipase A2 through a peptide‐enzyme complex

    Article • FEBS Letters, September 1995, Wiley

    PhD Ismael Mingarro

  98. Interfacial activation-based molecular bioimprinting of lipolytic enzymes.

    Article • Proceedings of the National Academy of Sciences, April 1995, Proceedings of the National Academy of Sciences

    PhD Ismael Mingarro

  99. Direct HPLC Monitoring of Lipase Activity in Reverse Micellar Media

    Article • Journal of Liquid Chromatography, January 1995, Taylor & Francis

    PhD Ismael Mingarro

  100. Characterization of Acylating and Deacylating Activities of an Extracellular Phospholipase A2 in a Water-Restricted Environment

    Article • Biochemistry, April 1994, American Chemical Society (ACS)

    PhD Ismael Mingarro