All Stories

  1. Structure of the Sap S-layer - the protective armor of the anthrax bacterium Bacillus anthracis.

    Article • Proceedings of the National Academy of Sciences, December 2024, Proceedings of the National Academy of Sciences

    Han Remaut

  2. Molecular dynamics and machine learning stratify motion-dependent activity profiles of S-layer destabilizing nanobodies

    Article • PNAS Nexus, November 2024, Oxford University Press (OUP)

    Han Remaut

  3. Colibactin-driven colon cancer requires adhesin-mediated epithelial binding

    Article • Nature, November 2024, Springer Science + Business Media

    Han Remaut

  4. Cryo-EM structure and polar assembly of the PS2 S-layer ofCorynebacterium glutamicum

    Article • September 2024, Cold Spring Harbor Laboratory Press

    Han Remaut

  5. The role of endospore appendages in spore–spore interactions in the pathogenic Bacillus cereus group

    Article • Environmental Microbiology, September 2024, Wiley

    Han Remaut

  6. Helical ultrastructure of the L-ENA spore aggregation factor of a Bacillus paranthracis foodborne outbreak strain

    Article • Nature Communications, August 2024, Springer Science + Business Media

    Han Remaut

  7. Lifecycle of a predatory bacterium vampirizing its prey through the cell envelope and S-layer

    Article • Nature Communications, April 2024, Springer Science + Business Media

    Han Remaut

  8. The role of endospore appendages in spore-spore contacts in pathogenic bacilli

    Article • April 2024, Cold Spring Harbor Laboratory Press

    Han Remaut

  9. CryoEM structure of a novel class of spore virulence factors on the foodborne outbreak strain Bacillus paranthracis NVH 0075-95

    Article • March 2024, Springer Science + Business Media

    Han Remaut

  10. Q586B2 is a crucial virulence factor during the early stages of Trypanosoma brucei infection that is conserved amongst trypanosomatids

    Article • Nature Communications, February 2024, Springer Science + Business Media

    Prof. Dr. ir. Benoit Stijlemans, Han Remaut

  11. Integrating artificial intelligence-based epitope prediction in a SARS-CoV-2 antibody discovery pipeline: caution is warranted

    Article • EBioMedicine, February 2024, Elsevier

    Johan Neyts, Han Remaut

  12. SlyB encapsulates outer membrane proteins in stress-induced lipid nanodomains

    Article • Nature, December 2023, Springer Science + Business Media

    Han Remaut

  13. Structure and function of the EA1 surface layer of Bacillus anthracis

    Article • Nature Communications, November 2023, Springer Science + Business Media

    Han Remaut

  14. Lifecycle of a predatory bacterium vampirizing its prey through the cell envelope and S-layer

    Article • October 2023, Cold Spring Harbor Laboratory Press

    Han Remaut

  15. A novel class of ultra-stable endospore appendages decorated with collagen-like tip fibrillae

    Article • October 2023, Cold Spring Harbor Laboratory Press

    Han Remaut

  16. Identification of small molecule antivirals against HTLV-1 by targeting the hDLG1-Tax-1 protein-protein interaction

    Article • Antiviral Research, September 2023, Elsevier

    Han Remaut

  17. Bypassing the Need for Cell Permeabilization: Nanobody CDR3 Peptide Improves Binding on Living Bacteria

    Article • Bioconjugate Chemistry, July 2023, American Chemical Society (ACS)

    Han Remaut

  18. Structural analysis and architectural principles of the bacterial amyloid curli

    Article • Nature Communications, May 2023, Springer Science + Business Media

    Han Remaut

  19. A molecular device for the redox quality control of GroEL/ES substrates

    Article • Cell, March 2023, Elsevier

    Han Remaut

  20. The Bacillus anthracis S-layer is an exoskeleton-like structure that imparts mechanical and osmotic stabilization to the cell wall

    Article • PNAS Nexus, August 2022, Oxford University Press (OUP)

    Han Remaut

  21. Structural analysis of the bacterial amyloid curli

    Article • February 2022, Cold Spring Harbor Laboratory Press

    Han Remaut

  22. Efficient long-range conduction in cable bacteria through nickel protein wires

    Article • Nature Communications, June 2021, Springer Science + Business Media

    Han Remaut

  23. Endospore Appendages: a novel pilus superfamily from the endospores of pathogenic Bacilli

    Article • The EMBO Journal, May 2021, Springer Science + Business Media

    Han Remaut

  24. Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM

    Article • Nature Chemical Biology, January 2021, Springer Science + Business Media

    Han Remaut

  25. The Bacillus anthracis Cell Envelope: Composition, Physiological Role, and Clinical Relevance

    Article • Microorganisms, November 2020, MDPI AG

    Han Remaut

  26. β-Barrels covalently link peptidoglycan and the outer membrane in the α-proteobacterium Brucella abortus

    Article • Nature Microbiology, November 2020, Springer Science + Business Media

    Han Remaut

  27. Synthesis of Fucose Derivatives with Thiol Motifs towards Suicide Inhibition of Helicobacter pylori

    Article • Molecules, September 2020, MDPI AG

    Han Remaut

  28. Bacillusendospore appendages form a novel family of disulfide-linked pili

    Article • August 2020, Cold Spring Harbor Laboratory Press

    Han Remaut

  29. An embedded lipid in the multidrug transporter LmrP suggests a mechanism for polyspecificity

    Article • Nature Structural & Molecular Biology, July 2020, Springer Science + Business Media

    Han Remaut

  30. A dual-constriction biological nanopore resolves homonucleotide sequences with high fidelity

    Article • Nature Biotechnology, July 2020, Springer Science + Business Media

    Han Remaut

  31. Structural insight into the formation of lipoprotein-β-barrel complexes

    Article • Nature Chemical Biology, June 2020, Springer Science + Business Media

    Han Remaut

  32. Cysteine Residues in Helicobacter pylori Adhesin HopQ Are Required for CEACAM–HopQ Interaction and Subsequent CagA Translocation

    Article • Microorganisms, March 2020, MDPI AG

    Han Remaut

  33. Curli Biogenesis: Bacterial Amyloid Assembly by the Type VIII Secretion Pathway

    Article • EcoSal Plus, December 2019, ASM Journals

    Han Remaut

  34. Selective Engagement of FcγRIV by a M2e-Specific Single Domain Antibody Construct Protects Against Influenza A Virus Infection

    Article • Frontiers in Immunology, December 2019, Frontiers

    Han Remaut

  35. Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM

    Article • October 2019, Cold Spring Harbor Laboratory Press

    Han Remaut

  36. Structure of S-layer protein Sap reveals a mechanism for therapeutic intervention in anthrax

    Article • Nature Microbiology, July 2019, Springer Science + Business Media

    Han Remaut

  37. Secreted amyloid-β precursor protein functions as a GABA B R1a ligand to modulate synaptic transmission

    Article • Science, January 2019, American Association for the Advancement of Science

    Han Remaut

  38. In silico proteomic and phylogenetic analysis of the outer membrane protein repertoire of gastric Helicobacter species

    Article • Scientific Reports, October 2018, Springer Science + Business Media

    Han Remaut

  39. The Role of Functional Amyloids in Bacterial Virulence

    Article • Journal of Molecular Biology, October 2018, Elsevier

    Han Remaut

  40. Hop‐family Helicobacter outer membrane adhesins form a novel class of Type 5‐like secretion proteins with an interrupted β‐barrel domain

    Article • Molecular Microbiology, September 2018, Wiley

    Han Remaut

  41. Helicobacter pylori adhesin HopQ disrupts trans dimerization in human CEACAMs

    Article • The EMBO Journal, June 2018, EMBO

    Han Remaut

  42. Future perspective for potential Helicobacter pylori eradication therapies

    Article • Future Microbiology, May 2018, Future Medicine

    Dr Han Remaut, Han Remaut

  43. Nucleation and growth of a bacterial functional amyloid at single-fiber resolution

    Article • Nature Chemical Biology, June 2017, Springer Science + Business Media

    Han Remaut

  44. Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist

    Article • Nature, June 2017, Springer Science + Business Media

    Han Remaut

  45. Evolution and structural dynamics of bacterial glycan binding adhesins

    Article • Current Opinion in Structural Biology, June 2017, Elsevier

    Han Remaut

  46. Bacterial RadA is a DnaB-type helicase interacting with RecA to promote bidirectional D-loop extension

    Article • Nature Communications, May 2017, Springer Science + Business Media

    Han Remaut

  47. Structural analysis of the interaction between spiroisoxazoline SMARt-420 and the Mycobacterium tuberculosis repressor EthR2

    Article • Biochemical and Biophysical Research Communications, May 2017, Elsevier

    Professor Franck Meyer, Han Remaut

  48. Helicobacter pylori Adapts to Chronic Infection and Gastric Disease via pH-Responsive BabA-Mediated Adherence

    Article • Cell Host & Microbe, March 2017, Elsevier

    Han Remaut

  49. Helicobacter pylori adhesin HopQ engages in a virulence-enhancing interaction with human CEACAMs

    Article • Nature Microbiology, October 2016, Springer Science + Business Media

    Han Remaut

  50. Inflammation-Induced Adhesin-Receptor Interaction Provides a Fitness Advantage to Uropathogenic E. coli during Chronic Infection

    Article • Cell Host & Microbe, October 2016, Elsevier

    Han Remaut

  51. Structural Insights into Polymorphic ABO Glycan Binding by Helicobacter pylori

    Article • Cell Host & Microbe, January 2016, Elsevier

    Han Remaut

  52. Bacterial Amyloid Formation: Structural Insights into Curli Biogensis

    Article • Trends in Microbiology, November 2015, Elsevier

    Han Remaut

  53. Crystal Structure of the Conserved Amino Terminus of the Extracellular Domain of Matrix Protein 2 of Influenza A Virus Gripped by an Antibody

    Article • Journal of Virology, October 2015, ASM Journals

    Xavier Saelens, Han Remaut

  54. Structural and adhesive properties of the long polar fimbriae protein LpfD from adherent-invasiveEscherichia coli

    Article • Acta Crystallographica Section D Biological Crystallography, July 2015, International Union of Crystallography

    Dr Han Remaut, Han Remaut

  55. Production, purification and crystallization of atrans-sialidase fromTrypanosoma vivax

    Article • Acta Crystallographica Section F Structural Biology Communications, April 2015, International Union of Crystallography

    Dr Yann G.-J. Sterckx, Han Remaut

  56. Structural and Functional Insight into the Carbohydrate Receptor Binding of F4 Fimbriae-producing Enterotoxigenic Escherichia coli

    Article • Journal of Biological Chemistry, March 2015, Elsevier

    Han Remaut

  57. Structural insight in the inhibition of adherence of F4 fimbriae producing enterotoxigenic Escherichia coli by llama single domain antibodies

    Article • Veterinary Research, February 2015, Springer Science + Business Media

    Han Remaut

  58. Nanobody Mediated Inhibition of Attachment of F18 Fimbriae Expressing Escherichia coli

    Article • PLoS ONE, December 2014, PLOS

    Professor Eric Cox, Han Remaut

  59. Expression, purification and X-ray crystallographic analysis of theHelicobacter pyloriblood group antigen-binding adhesin BabA

    Article • Acta Crystallographica Section F Structural Biology Communications, November 2014, International Union of Crystallography

    Dr Han Remaut, Han Remaut

  60. Lifting the lid on pilus assembly

    Article • eLife, October 2014, eLife

    Dr Han Remaut, Nir Ben-Tal, Han Remaut

  61. Structural and mechanistic insights into the bacterial amyloid secretion channel CsgG

    Article • Nature, September 2014, Springer Science + Business Media

    Han Remaut

  62. Bacterial Surface Appendages as Targets for Novel Antibacterial Therapeutics

    Article • Future Microbiology, July 2014, Taylor & Francis

    Han Remaut

  63. SbsB structure and lattice reconstruction unveil Ca2+ triggered S-layer assembly

    Article • Nature, June 2012, Springer Science + Business Media

    Han Remaut

  64. Structural Determinants of Polymerization Reactivity of the P pilus Adaptor Subunit PapF

    Article • Structure, November 2008, Elsevier

    Han Remaut

  65. Unraveling the molecular basis of subunit specificity in P pilus assembly by mass spectrometry

    Article • Proceedings of the National Academy of Sciences, September 2008, Proceedings of the National Academy of Sciences

    Han Remaut

  66. Architectures and biogenesis of non-flagellar protein appendages in Gram-negative bacteria

    Article • The EMBO Journal, July 2008, Springer Science + Business Media

    Han Remaut

  67. Structural Analysis of the Saf Pilus by Electron Microscopy and Image Processing

    Article • Journal of Molecular Biology, May 2008, Elsevier

    Han Remaut

  68. Fiber Formation across the Bacterial Outer Membrane by the Chaperone/Usher Pathway

    Article • Cell, May 2008, Elsevier

    Han Remaut

  69. Rationally designed small compounds inhibit pilus biogenesis in uropathogenic bacteria

    Article • Proceedings of the National Academy of Sciences, November 2006, Proceedings of the National Academy of Sciences

    Han Remaut

  70. Molecular mechanism of P pilus termination in uropathogenic Escherichia coli

    Article • EMBO Reports, November 2006, Springer Science + Business Media

    Han Remaut

  71. Protein–protein interaction through β-strand addition

    Article • Trends in Biochemical Sciences, August 2006, Elsevier

    Han Remaut

  72. Donor-Strand Exchange in Chaperone-Assisted Pilus Assembly Proceeds through a Concerted β Strand Displacement Mechanism

    Article • Molecular Cell, June 2006, Elsevier

    Han Remaut

  73. Fiber assembly by the chaperone–usher pathway

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, November 2004, Elsevier

    Han Remaut

  74. Crystal Structure of T State Aspartate Carbamoyltransferase of the Hyperthermophilic Archaeon Sulfolobus acidocaldarius

    Article • Journal of Molecular Biology, June 2004, Elsevier

    Han Remaut

  75. Structural biology of bacterial pathogenesis

    Article • Current Opinion in Structural Biology, April 2004, Elsevier

    Han Remaut

  76. Molecular characterization of Bacillus pasteurii UreE, a metal-binding chaperone for the assembly of the urease active site

    Article • JBIC Journal of Biological Inorganic Chemistry, February 2002, Springer Science + Business Media

    Professor Stefano Ciurli, Han Remaut

  77. Crystallization and preliminary X-ray crystallographic analysis of glutathione amide reductase fromChromatium gracile

    Article • Acta Crystallographica Section D Biological Crystallography, January 2002, International Union of Crystallography

    Han Remaut

  78. Structural Basis for Ni2+Transport and Assembly of the Urease Active Site by the Metallochaperone UreE from Bacillus pasteurii

    Article • Journal of Biological Chemistry, October 2001, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Stefano Ciurli, Han Remaut

  79. Article • Nature Structural Biology, August 2001, Springer Science + Business Media

    Han Remaut

  80. Crystal structure of a d-aminopeptidase from Ochrobactrum anthropi, a new member of the ‘penicillin-recognizing enzyme’ family

    Article • Structure, September 2000, Elsevier

    Han Remaut