All Stories

  1. Superoxide Anion Production and Bioenergetic Profile in Young and Elderly Human Primary Myoblasts

    Article • Oxidative Medicine and Cellular Longevity, July 2018, Hindawi Publishing Corporation

    Giovanni Monaco, Mariangela Marrone

  2. A double point mutation at residues Ile14 and Val15 of Bcl-2 uncovers a role for the BH4 domain in both protein stability and function

    Article • FEBS Journal, December 2017, Wiley

    Giovanni Monaco

  3. Modulation of Ca2+ Signaling by Anti-apoptotic B-Cell Lymphoma 2 Proteins at the Endoplasmic Reticulum–Mitochondrial Interface

    Article • Frontiers in Oncology, May 2017, Frontiers

    Giovanni Monaco

  4. The trans-membrane domain of Bcl-2α, but not its hydrophobic cleft, is a critical determinant for efficient IP3 receptor inhibition

    Article • Oncotarget, August 2016, Impact Journals, LLC

    Giovanni Monaco

  5. Ryanodine receptors are targeted by anti-apoptotic Bcl-XL involving its BH4 domain and Lys87 from its BH3 domain

    Article • Scientific Reports, April 2015, Nature

    Giovanni Monaco

  6. Endoplasmic reticulum Ca2+ content decrease by PKA-dependent hyperphosphorylation of type 1 IP3 receptor contributes to prostate cancer cell resistance to androgen deprivation

    Article • Cell Calcium, April 2015, Elsevier

    Giovanni Monaco

  7. The BH4 Domain of Anti-apoptotic Bcl-XL, but Not That of the Related Bcl-2, Limits the Voltage-dependent Anion Channel 1 (VDAC1)-mediated Transfer of Pro-apoptotic Ca2+Signals to Mitochondria

    Article • Journal of Biological Chemistry, February 2015, American Society for Biochemistry & Molecular Biology (ASBMB)

    Giovanni Monaco

  8. Abstract B42: The regulation of the ER-mitochondria-Ca2+ cross-talk by Bcl-2 and Bcl-XL: A new scenario for the development of selective tools in oncology?

    Article • Cancer Research, October 2013, American Association for Cancer Research (AACR)

    Giovanni Monaco

  9. Alpha-Helical Destabilization of the Bcl-2-BH4-Domain Peptide Abolishes Its Ability to Inhibit the IP3 Receptor

    Article • PLoS ONE, August 2013, PLOS

    Professor Wim M De Borggraeve, Giovanni Monaco

  10. Profiling of the Bcl-2/Bcl-XL-binding sites on type 1 IP3 receptor

    Article • Biochemical and Biophysical Research Communications, November 2012, Elsevier

    Giovanni Monaco

  11. The selective BH4-domain biology of Bcl-2-family members: IP3Rs and beyond

    Article • Cellular and Molecular Life Sciences, September 2012, Springer Science + Business Media

    Giovanni Monaco

  12. Faculty of 1000 evaluation for Selective regulation of IP3-receptor-mediated Ca2+ signaling and apoptosis by the BH4 domain of Bcl-2 versus Bcl-Xl.

    Article • August 2011, Faculty of 1000, Ltd.

    Giovanni Monaco

  13. Selective regulation of IP3-receptor-mediated Ca2+ signaling and apoptosis by the BH4 domain of Bcl-2 versus Bcl-Xl

    Article • Cell Death and Differentiation, August 2011, Nature

    Giovanni Monaco

  14. The IP3 receptor–mitochondria connection in apoptosis and autophagy

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, May 2011, Elsevier

    Giovanni Monaco

  15. IP3Receptors, Mitochondria, and Ca2+Signaling: Implications for Aging

    Article • Journal of Aging Research, January 2011, Hindawi Publishing Corporation

    Giovanni Monaco

  16. Induction of Ca2+-driven apoptosis in chronic lymphocytic leukemia cells by peptide-mediated disruption of Bcl-2-IP3 receptor interaction

    Article • Blood, December 2010, American Society of Hematology

    Giovanni Monaco

  17. STIM1, but not STIM2, is required for proper agonist-induced Ca2+ signaling

    Article • Cell Calcium, August 2010, Elsevier

    Giovanni Monaco

  18. The effect of the cyclin-dependent kinase inhibitor flavopiridol on anaplastic large cell lymphoma cells and relationship with NPM-ALK kinase expression and activity

    Article • Haematologica, June 2009, Ferrata Storti Foundation (Haematologica)

    Giovanni Monaco

  19. Odorant receptors at the growth cone are coupled to localized cAMP and Ca 2+ increases

    Article • Proceedings of the National Academy of Sciences, March 2009, Proceedings of the National Academy of Sciences

    Giovanni Monaco

  20. 295 POSTER Growth inhibition and induction of apoptosis in anaplastic large cell lymphoma cells treated with the CDK inhibitor flavopiridol

    Article • European Journal of Cancer Supplements, October 2008, Elsevier

    Giovanni Monaco