All Stories

  1. Bivalent chromatin accommodates survivin and BRG1/SWI complex to activate DNA damage response in CD4+ cells
  2. Appraising protein conformational changes by resampling time-resolved serial x-ray crystallography data
  3. Searching for the Simplest Explanation of How Proteins Recognize Each Other
  4. Femtosecond X-ray snapshots reveal correlated displacements of specific distal atoms in a protein crystal
  5. The structure of the second CysD domain of MUC2 and role in mucin organization by transglutaminase-based cross-linking
  6. SURVIVIN IN SYNERGY WITH BAF/SWI COMPLEX BINDS BIVALENT CHROMATIN REGIONS AND ACTIVATES DNA DAMAGE RESPONSE IN CD4+ T CELLS
  7. Deciphering Peptide-Protein Interactions via Composition-Based Prediction: A Case Study with Survivin/BIRC5
  8. The Role of the Protein Survivin in Hindering Cellular Specialization
  9. Survivin prevents the Polycomb Repressor Complex 2 from methylating Histone 3 lysine 27
  10. Bayesian progress curve analysis of MicroScale thermophoresis data
  11. Chromatin bound by survivin regulates the glycolytic switch in interferon-γ producing CD4+ T cells
  12. Chromatin binding of survivin regulates glucose metabolism in the IFN-γ producing CD4+ T cells
  13. Estimating the probability of coincidental similarity between atomic displacement parameters with machine learning
  14. Chemical mapping exposes the importance of active site interactions in governing the temperature dependence of enzyme turnover
  15. An instrument for catching ultrafast protein movement at FemtoMAX.
  16. Ultrafast structural changes within a photosynthetic reaction centre
  17. A THz transparent 3D printed microfluidic cell for small angle x-ray scattering
  18. A tool for visualizing protein motions in time-resolved crystallography
  19. In cellulo crystallization of Trypanosoma brucei IMP dehydrogenase enables the identification of genuine co-factors
  20. Clustering of atomic displacement parameters in bovine trypsin reveals a distributed lattice of atoms with shared chemical properties
  21. Revealing the starting picture of large molecules is getting easier with machine learning
  22. Patterns of anisotropic temperature factors in bovine trypsin crystals with and without 0.5 THz irradiation:
  23. A practical guide to developing virtual and augmented reality exercises for teaching structural biology
  24. Bayesian Analysis of MicroScale Thermophoresis Data to Quantify Affinity of Protein:Protein Interactions with Human Survivin
  25. Regulation of the Equilibrium between Closed and Open Conformations of Annexin A2 by N-Terminal Phosphorylation and S100A4-Binding
  26. Survivin in autoimmune diseases
  27. The value of exceptional intensity observations
  28. Bayesian analysis of non-thermal structural changes induced by terahertz radiation in protein crystals
  29. Correlated measurements are interpreted better with machine learning
  30. A new way of making protein molecules dance in unison
  31. Survivin co-ordinates formation of follicular T-cells acting in synergy with Bcl-6
  32. Conformational activation of visual rhodopsin in native disc membranes
  33. DYNLL2 Dynein Light Chain Binds to an Extended Linear Motif of Myosin 5a Tail That Has Structural Plasticity
  34. Visualizing a protein quake with time-resolved X-ray scattering at a free-electron laser
  35. The C-Terminal Random Coil Region Tunes the Ca2+-Binding Affinity of S100A4 through Conformational Activation
  36. Terahertz absorption of illuminated photosynthetic reaction center solution: a signature of photoactivation?
  37. Correction: Terahertz absorption of illuminated photosynthetic reaction center solution: a signature of photoactivation?
  38. Structure of a photosynthetic reaction centre determined by serial femtosecond crystallography
  39. Comparison of complexes formed by a crustacean and a vertebrate trypsin with bovine pancreatic trypsin inhibitor - the key to achieving extreme stability?
  40. Natively Inhibited Trypanosoma brucei Cathepsin B Structure Determined by Using an X-ray Laser
  41. Structural Characterization of Bacterioferritin from Blastochloris viridis
  42. High-Resolution Protein Structure Determination by Serial Femtosecond Crystallography
  43. Crystal structure of the S100A4–nonmuscle myosin IIA tail fragment complex reveals an asymmetric target binding mechanism
  44. Lipidic phase membrane protein serial femtosecond crystallography
  45. Hugging Interaction: Asymmetric Binding of Metastasis Associated Protein S100A4 to Non-Muscle Myosin 2A Tail
  46. Time-Resolved WAXS Reveals Accelerated Conformational Changes in Iodoretinal-Substituted Proteorhodopsin
  47. Directed Evolution Reveals the Binding Motif Preference of the LC8/DYNLL Hub Protein and Predicts Large Numbers of Novel Binders in the Human Proteome
  48. The Catalytic Aspartate Is Protonated in the Michaelis Complex Formed between Trypsin and anin VitroEvolved Substrate-like Inhibitor
  49. Rapid readout detector captures protein time-resolved WAXS
  50. Light-Induced Structural Changes in a Photosynthetic Reaction Center Caught by Laue Diffraction
  51. Time-resolved structural studies of protein reaction dynamics: a smorgasbord of X-ray approaches
  52. Structural Dynamics of Light-Driven Proton Pumps
  53. Lipidic Sponge Phase Crystal Structure of a Photosynthetic Reaction Center Reveals Lipids on the Protein Surface
  54. Structural Dynamics of Light-Driven Proton Pumps
  55. Membrane protein crystallization from lipidic phases
  56. Raman-Assisted X-Ray Crystallography for the Analysis of Biomolecules
  57. A Lipidic-Sponge Phase Screen for Membrane Protein Crystallization
  58. Probing the Dynamic Interface between Trimethylamine Dehydrogenase (TMADH) and Electron Transferring Flavoprotein (ETF) in the TMADH−2ETF Complex: Role of the Arg-α237 (ETF) and Tyr-442 (TMADH) Residue Pair†,‡
  59. The Crystal Structure of a Trypsin-like Mutant Chymotrypsin: The Role of Position 226 in the Activity and Specificity of S189D Chymotrypsin
  60. Raman-Assisted Crystallography Reveals End-On Peroxide Intermediates in a Nonheme Iron Enzyme
  61. Lipidic Sponge Phase Crystallization of Membrane Proteins
  62. Enzyme:Substrate Hydrogen Bond Shortening during the Acylation Phase of Serine Protease Catalysis†
  63. Extended Intermolecular Interactions in a Serine Protease–Canonical Inhibitor Complex Account for Strong and Highly Specific Inhibition
  64. Structural Determination of a Transient Isomer ofCH2I2by Picosecond X-Ray Diffraction
  65. Conformational regulation of charge recombination reactions in a photosynthetic bacterial reaction center
  66. Structural and evolutionary consequences of unpaired cysteines in trypsinogen
  67. Lipidic Cubic Phase Crystal Structure of the Photosynthetic Reaction Centre from Rhodobacter sphaeroides at 2.35Å Resolution
  68. Projecting picosecond lattice dynamics through x-ray topography
  69. X-ray Structure of a Serine Protease Acyl-Enzyme Complex at 0.95-Å Resolution
  70. Crystal structure reveals basis for the inhibitor resistance of human brain trypsin
  71. Comparativein VitroStudies on Native and Recombinant Human Cationic Trypsins