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  1. Hypertension: Causes and Consequences of Circadian Rhythms in Blood Pressure

    Article • Circulation Research, March 2024, Wolters Kluwer Health

    Frank A.J.L. Scheer

  2. Publisher Correction: Impact of polygenic score for BMI on weight loss effectiveness and genome-wide association analysis

    Article • International Journal of Obesity, March 2024, Springer Science + Business Media

    Frank A.J.L. Scheer

  3. Light exposure during sleep is bidirectionally associated with irregular sleep timing: The multi-ethnic study of atherosclerosis (MESA)

    Article • Environmental Pollution, March 2024, Elsevier

    Frank A.J.L. Scheer

  4. The sleep–circadian interface: A window into mental disorders

    Article • Proceedings of the National Academy of Sciences, February 2024, Proceedings of the National Academy of Sciences

    Frank A.J.L. Scheer

  5. Impact of polygenic score for BMI on weight loss effectiveness and genome-wide association analysis

    Article • International Journal of Obesity, January 2024, Springer Science + Business Media

    Frank A.J.L. Scheer

  6. Social jetlag and obesity: A systematic review and meta‐analysis

    Article • Obesity Reviews, December 2023, Wiley

    Frank A.J.L. Scheer

  7. The Negative Effects of Travel on Student Athletes Through Sleep and Circadian Disruption

    Article • Journal of Biological Rhythms, November 2023, SAGE Publications

    Frank A.J.L. Scheer

  8. CIRCUST: A novel methodology for temporal order reconstruction of molecular rhythms; validation and application towards a daily rhythm gene expression atlas in humans

    Article • PLoS Computational Biology, September 2023, PLOS

    Frank A.J.L. Scheer

  9. Circadian misalignment increases 24‐hour acylated ghrelin in chronic shift workers: a randomized crossover trial

    Article • Obesity, August 2023, Wiley

    Frank A.J.L. Scheer

  10. Social jetlag and dietary intake: A systematic review

    Article • Sleep Medicine Reviews, July 2023, Elsevier

    Frank A.J.L. Scheer

  11. Association of Timing of Moderate-to-Vigorous Physical Activity With Changes in Glycemic Control Over 4 Years in Adults With Type 2 Diabetes From the Look AHEAD Trial

    Article • Diabetes Care, May 2023, American Diabetes Association

    Frank A.J.L. Scheer

  12. Best Time of Day for Strength and Endurance Training to Improve Health and Performance? A Systematic Review with Meta-analysis

    Article • Sports Medicine - Open, May 2023, Springer Science + Business Media

    Frank A.J.L. Scheer

  13. Effects of Sleep Fragmentation and Estradiol Decline on Cortisol in a Human Experimental Model of Menopause

    Article • The Journal of Clinical Endocrinology & Metabolism, May 2023, Endocrine Society

    Frank A.J.L. Scheer

  14. Evening types as determined by subjective and objective measures are more emotional eaters

    Article • Obesity, April 2023, Wiley

    Frank A.J.L. Scheer

  15. Lifestyle mediators of associations among siestas, obesity, and metabolic health

    Article • Obesity, April 2023, Wiley

    Frank A.J.L. Scheer

  16. Sleep behavior traits and associations with opioid-related adverse events: a cohort study

    Article • SLEEP, April 2023, Oxford University Press (OUP)

    Frank A.J.L. Scheer

  17. CIRCUST: a novel methodology for temporal order reconstruction of molecular rhythms; validation and application towards a daily rhythm gene expression atlas in humans

    Article • December 2022, Cold Spring Harbor Laboratory Press

    Frank A.J.L. Scheer

  18. Keeping an eye on circadian time in clinical research and medicine

    Article • Clinical and Translational Medicine, December 2022, Wiley

    Frank A.J.L. Scheer

  19. Research gaps and opportunities in precision nutrition: an NIH workshop report

    Article • American Journal of Clinical Nutrition, December 2022, Elsevier

    Frank A.J.L. Scheer

  20. Desynchronizing the sleep­­–wake cycle from circadian timing to assess their separate contributions to physiology and behaviour and to estimate intrinsic circadian period

    Article • Nature Protocols, November 2022, Springer Science + Business Media

    Frank A.J.L. Scheer

  21. Actigraphy-Based Sleep Detection: Validation with Polysomnography and Comparison of Performance for Nighttime and Daytime Sleep During Simulated Shift Work

    Article • Nature and Science of Sleep, October 2022, Taylor & Francis

    Frank A.J.L. Scheer

  22. Late isocaloric eating increases hunger, decreases energy expenditure, and modifies metabolic pathways in adults with overweight and obesity

    Article • Cell Metabolism, October 2022, Elsevier

    Frank A.J.L. Scheer

  23. Daytime eating prevents mood vulnerability in night work

    Article • Proceedings of the National Academy of Sciences, September 2022, Proceedings of the National Academy of Sciences

    Frank A.J.L. Scheer

  24. A matter of time: A systematic scoping review on a potential role of the circadian system in binge eating behavior

    Article • Frontiers in Nutrition, September 2022, Frontiers

    Frank A.J.L. Scheer

  25. Genetics of circadian rhythms and sleep in human health and disease

    Article • Nature Reviews Genetics, August 2022, Springer Science + Business Media

    Frank A.J.L. Scheer

  26. Later energy intake relative to mathematically modeled circadian time is associated with higher percentage body fat

    Article • Obesity, June 2022, Wiley

    Frank A.J.L. Scheer

  27. Sleep Fragmentation and Estradiol Suppression Decrease Fat Oxidation in Premenopausal Women

    Article • The Journal of Clinical Endocrinology & Metabolism, May 2022, Endocrine Society

    Frank A.J.L. Scheer

  28. Chronic circadian disruption on a high-fat diet impairs glucose tolerance

    Article • Metabolism, May 2022, Elsevier

    Frank A.J.L. Scheer

  29. Unanticipated daytime melatonin secretion on a simulated night shift schedule generates a distinctive 24‐h melatonin rhythm with antiphasic daytime and nighttime peaks

    Article • Journal of Pineal Research, March 2022, Wiley

    Frank A.J.L. Scheer

  30. A Novel Home-Based Study of Circadian Rhythms: Design, Rationale, and Methods for the Circadia Study

    Article • February 2022, Cold Spring Harbor Laboratory Press

    Frank A.J.L. Scheer

  31. How Accurately Can We Recall the Timing of Food Intake? A Comparison of Food Times from Recall-Based Survey Questions and Daily Food Records

    Article • Current Developments in Nutrition, February 2022, Elsevier

    Frank A.J.L. Scheer

  32. Interplay of Dinner Timing and MTNR1B Type 2 Diabetes Risk Variant on Glucose Tolerance and Insulin Secretion: A Randomized Crossover Trial

    Article • Diabetes Care, January 2022, American Diabetes Association

    Frank A.J.L. Scheer

  33. Proof‐of‐principle demonstration of endogenous circadian system and circadian misalignment effects on human oral microbiota

    Article • The FASEB Journal, December 2021, Wiley

    Frank A.J.L. Scheer

  34. Daytime eating prevents internal circadian misalignment and glucose intolerance in night work

    Article • Science Advances, December 2021, American Association for the Advancement of Science

    Frank A.J.L. Scheer

  35. Heart rate response and recovery during exercise predict future delirium risk—A prospective cohort study in middle- to older-aged adults

    Article • Journal of Sport and Health Science, December 2021, Elsevier

    Frank A.J.L. Scheer

  36. Understanding Circadian Mechanisms of Sudden Cardiac Death: A Report From the National Heart, Lung, and Blood Institute Workshop, Part 1: Basic and Translational Aspects

    Article • Circulation Arrhythmia and Electrophysiology, November 2021, Wolters Kluwer Health

    Frank A.J.L. Scheer

  37. Understanding Circadian Mechanisms of Sudden Cardiac Death: A Report From the National Heart, Lung, and Blood Institute Workshop, Part 2: Population and Clinical Considerations

    Article • Circulation Arrhythmia and Electrophysiology, November 2021, Wolters Kluwer Health

    Frank A.J.L. Scheer

  38. Chronic Sleep Restriction While Minimizing Circadian Disruption Does Not Adversely Affect Glucose Tolerance

    Article • Frontiers in Physiology, October 2021, Frontiers

    Frank A.J.L. Scheer

  39. Association of Poor Sleep Burden in Middle Age and Older Adults With Risk for Delirium During Hospitalization

    Article • The Journals of Gerontology Series A, September 2021, Oxford University Press (OUP)

    Frank A.J.L. Scheer

  40. Human circadian clock worsens asthma at night

    Article • Proceedings of the National Academy of Sciences, September 2021, Proceedings of the National Academy of Sciences

    Frank A.J.L. Scheer, Steven A Shea

  41. Diurnal Variation in Maximum Endurance and Maximum Strength Performance: A Systematic Review and Meta-analysis

    Article • Medicine & Science in Sports & Exercise, August 2021, Wolters Kluwer Health

    Frank A.J.L. Scheer

  42. Timing of chocolate intake affects hunger, substrate oxidation, and microbiota: A randomized controlled trial

    Article • The FASEB Journal, June 2021, Wiley

    Frank A.J.L. Scheer

  43. Poor sleep behavior burden and risk of COVID-19 mortality and hospitalization

    Article • SLEEP, June 2021, Oxford University Press (OUP)

    Frank A.J.L. Scheer

  44. Circadian Biology and Stroke

    Article • Stroke, June 2021, Wolters Kluwer Health

    Frank A.J.L. Scheer

  45. Cross-Sectional and Prospective Associations of Rest–Activity Rhythms With Circulating Inflammatory Markers in Older Men

    Article • The Journals of Gerontology Series A, April 2021, Oxford University Press (OUP)

    Frank A.J.L. Scheer

  46. Association of Objectively Measured Timing of Physical Activity Bouts With Cardiovascular Health in Type 2 Diabetes

    Article • Diabetes Care, February 2021, American Diabetes Association

    Jingyi Qian, Frank A.J.L. Scheer

  47. Resting Heartbeat Complexity Predicts All‐Cause and Cardiorespiratory Mortality in Middle‐ to Older‐Aged Adults From the UK Biobank

    Article • Journal of the American Heart Association, February 2021, Wolters Kluwer Health

    Frank A.J.L. Scheer

  48. Late eating is associated with cardiometabolic risk traits, obesogenic behaviors, and impaired weight loss

    Article • American Journal of Clinical Nutrition, January 2021, Elsevier

    Frank A.J.L. Scheer

  49. Stability of the timing of food intake at daily and monthly timescales in young adults

    Article • Scientific Reports, November 2020, Springer Science + Business Media

    Frank A.J.L. Scheer

  50. Blunted rest–activity rhythms link to higher body mass index and inflammatory markers in children

    Article • SLEEP, November 2020, Oxford University Press (OUP)

    Frank A.J.L. Scheer

  51. Night shift work is associated with an increased risk of asthma

    Article • Thorax, November 2020, BMJ

    Frank A.J.L. Scheer

  52. Circadian misalignment increases mood vulnerability in simulated shift work

    Article • Scientific Reports, October 2020, Springer Science + Business Media

    Frank A.J.L. Scheer

  53. Late Eating Is Associated with Obesity, Inflammatory Markers and Circadian-Related Disturbances in School-Aged Children

    Article • Nutrients, September 2020, MDPI AG

    Frank A.J.L. Scheer

  54. Cross-sectional and Prospective Associations of Rest-Activity Rhythms With Metabolic Markers and Type 2 Diabetes in Older Men

    Article • Diabetes Care, September 2020, American Diabetes Association

    Frank A.J.L. Scheer

  55. Circadian Rhythms in Hormone-sensitive Lipase in Human Adipose Tissue: Relationship to Meal Timing and Fasting Duration

    Article • The Journal of Clinical Endocrinology & Metabolism, July 2020, Endocrine Society

    Frank A.J.L. Scheer

  56. Night Shift Work Increases the Risk of Asthma

    Article • April 2020, Cold Spring Harbor Laboratory Press

    Frank A.J.L. Scheer

  57. Effects of Shift Work on the Eating Behavior of Police Officers on Patrol

    Article • Nutrients, April 2020, MDPI AG

    Frank A.J.L. Scheer

  58. Fractal biomarker of activity in patients with bipolar disorder

    Article • Psychological Medicine, April 2020, Cambridge University Press

    Frank A.J.L. Scheer

  59. Effects of obstructive sleep apnea on endogenous circadian rhythms assessed during relaxed wakefulness; an exploratory analysis

    Article • Chronobiology International, March 2020, Taylor & Francis

    Frank A.J.L. Scheer

  60. Melatonin Effects on Glucose Metabolism: Time To Unlock the Controversy

    Article • Trends in Endocrinology and Metabolism, March 2020, Elsevier

    Frank A.J.L. Scheer

  61. Impact of circadian disruption on glucose metabolism: implications for type 2 diabetes

    Article • Diabetologia, January 2020, Springer Science + Business Media

    Frank A.J.L. Scheer

  62. Health consequences of circadian disruption

    Article • SLEEP, January 2020, Oxford University Press (OUP)

    Frank A.J.L. Scheer

  63. Assessment of MTNR1B Type 2 Diabetes Genetic Risk Modification by Shift Work and Morningness-Eveningness Preference in the UK Biobank

    Article • Diabetes, November 2019, American Diabetes Association

    Frank A.J.L. Scheer

  64. Sex-dependent link between circadian misalignment and adiposity

    Article • Nature Reviews Endocrinology, November 2019, Springer Science + Business Media

    Frank A.J.L. Scheer

  65. Sex differences in the circadian misalignment effects on energy regulation

    Article • Proceedings of the National Academy of Sciences, November 2019, Proceedings of the National Academy of Sciences

    Frank A.J.L. Scheer

  66. The circadian system modulates the rate of recovery of systolic blood pressure after exercise in humans

    Article • SLEEP, October 2019, Oxford University Press (OUP)

    Frank A.J.L. Scheer, Steven A Shea

  67. Impact of Circadian Disruption on Cardiovascular Function and Disease

    Article • Trends in Endocrinology and Metabolism, October 2019, Elsevier

    Frank A.J.L. Scheer

  68. Genome-wide association analysis of self-reported daytime sleepiness identifies 42 loci that suggest biological subtypes

    Article • Nature Communications, August 2019, Springer Science + Business Media

    Frank A.J.L. Scheer

  69. Genome-wide association study of breakfast skipping links clock regulation with food timing

    Article • American Journal of Clinical Nutrition, August 2019, Elsevier

    Frank A.J.L. Scheer

  70. Timing of Food Intake: Identifying Contributing Factors to Design Effective Interventions

    Article • Advances in Nutrition, May 2019, Oxford University Press (OUP)

    Frank A.J.L. Scheer

  71. Impact of mental stress, the circadian system and their interaction on human cardiovascular function

    Article • Psychoneuroendocrinology, May 2019, Elsevier

    Steven A Shea, Frank A.J.L. Scheer

  72. Heritability of the timing of food intake

    Article • Clinical Nutrition, April 2019, Elsevier

    Frank A.J.L. Scheer

  73. Chronotype Genetic Variant in PER2 is Associated with Intrinsic Circadian Period in Humans

    Article • Scientific Reports, March 2019, Springer Science + Business Media

    Frank A.J.L. Scheer

  74. Caloric and Macronutrient Intake Differ with Circadian Phase and between Lean and Overweight Young Adults

    Article • Nutrients, March 2019, MDPI AG

    Frank A.J.L. Scheer

  75. Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates

    Article • Nature Communications, March 2019, Springer Science + Business Media

    Frank A.J.L. Scheer

  76. Biological and clinical insights from genetics of insomnia symptoms

    Article • Nature Genetics, February 2019, Springer Science + Business Media

    Frank A.J.L. Scheer

  77. Nocturnal heart rate variability moderates the association between sleep–wake regularity and mood in young adults

    Article • SLEEP, February 2019, Oxford University Press (OUP)

    Frank A.J.L. Scheer

  78. A healthy lifestyle — reducing T2DM risk in shift workers?

    Article • Nature Reviews Endocrinology, February 2019, Springer Science + Business Media

    Frank A.J.L. Scheer

  79. Meal timing and obesity: interactions with macronutrient intake and chronotype

    Article • International Journal of Obesity, January 2019, Springer Science + Business Media

    Frank A.J.L. Scheer

  80. Effects of circadian misalignment on cognition in chronic shift workers

    Article • Scientific Reports, January 2019, Springer Science + Business Media

    Frank A.J.L. Scheer

  81. Circadian period of luciferase expression shortens with age in human mature adipocytes from obese patients

    Article • The FASEB Journal, January 2019, Federation of American Societies For Experimental Biology (FASEB)

    Marta Garaulet, Frank A.J.L. Scheer

  82. Circadian clocks and insulin resistance

    Article • Nature Reviews Endocrinology, December 2018, Springer Science + Business Media

    Andries Kalsbeek, Frank A.J.L. Scheer

  83. Genome-wide association analysis of excessive daytime sleepiness identifies 42 loci that suggest phenotypic subgroups

    Article • October 2018, Cold Spring Harbor Laboratory Press

    Frank A.J.L. Scheer

  84. Ghrelin is impacted by the endogenous circadian system and by circadian misalignment in humans

    Article • International Journal of Obesity, September 2018, Springer Science + Business Media

    Frank A.J.L. Scheer

  85. Late dinner impairs glucose tolerance in MTNR1B risk allele carriers: A randomized, cross-over study

    Article • Clinical Nutrition, August 2018, Elsevier

    Frank A.J.L. Scheer

  86. Circadian misalignment induces fatty acid metabolism gene profiles and compromises insulin sensitivity in human skeletal muscle

    Article • Proceedings of the National Academy of Sciences, July 2018, Proceedings of the National Academy of Sciences

    Frank A.J.L. Scheer

  87. Differential effects of the circadian system and circadian misalignment on insulin sensitivity and insulin secretion in humans

    Article • Diabetes Obesity and Metabolism, July 2018, Wiley

    Frank A.J.L. Scheer

  88. Fractal regulation and incident Alzheimer's disease in elderly individuals

    Article • Alzheimer s & Dementia, May 2018, Wiley

    Frank A.J.L. Scheer, Steven A Shea

  89. GWAS in 446,118 European adults identifies 78 genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates

    Article • April 2018, Cold Spring Harbor Laboratory Press

    Frank A.J.L. Scheer

  90. Daily circadian misalignment impairs human cognitive performance task-dependently

    Article • Scientific Reports, February 2018, Springer Science + Business Media

    Frank A.J.L. Scheer

  91. Night Shift Work, Genetic Risk, and Type 2 Diabetes in the UK Biobank

    Article • Diabetes Care, February 2018, American Diabetes Association

    Frank A.J.L. Scheer

  92. Biological and clinical insights from genetics of insomnia symptoms

    Article • February 2018, Cold Spring Harbor Laboratory Press

    Frank A.J.L. Scheer

  93. Modifiable lifestyle behaviors, but not a genetic risk score, associate with metabolic syndrome in evening chronotypes

    Article • Scientific Reports, January 2018, Springer Science + Business Media

    Frank A.J.L. Scheer

  94. Heparin-Induced Thrombocytopenia in Healthy Individuals with Continuous Heparin Infusion

    Article • TH Open, January 2018, Thieme Publishing Group

    Frank A.J.L. Scheer

  95. Timing of food intake impacts daily rhythms of human salivary microbiota: a randomized, crossover study

    Article • The FASEB Journal, December 2017, Federation of American Societies For Experimental Biology (FASEB)

    Frank A.J.L. Scheer

  96. Decrease in scale invariance of activity fluctuations with aging and in patients with suprasellar tumors

    Article • Chronobiology International, November 2017, Taylor & Francis

    Frank A.J.L. Scheer

  97. Later circadian timing of food intake is associated with increased body fat

    Article • American Journal of Clinical Nutrition, September 2017, Oxford University Press (OUP)

    Frank A.J.L. Scheer

  98. Erratum. Gene-Environment Interactions of Circadian-Related Genes for Cardiometabolic Traits. Diabetes Care 2015;38:1456–1466

    Article • Diabetes Care, August 2017, American Diabetes Association

    Frank A.J.L. Scheer

  99. CLOCK 3111T/C genetic variant influences the daily rhythm of autonomic nervous function: relevance to body weight control

    Article • International Journal of Obesity, July 2017, Springer Science + Business Media

    Frank A.J.L. Scheer

  100. Circadian Biology: Uncoupling Human Body Clocks by Food Timing

    Article • Current Biology, July 2017, Elsevier

    Frank A.J.L. Scheer

  101. Reduced Tolerance to Night Shift in Chronic Shift Workers: Insight From Fractal Regulation

    Article • SLEEP, July 2017, Oxford University Press (OUP)

    Frank A.J.L. Scheer

  102. 0208 CIRCADIAN MISALIGNMENT IMPACTS ON HUMAN COGNITIVE PERFORMANCE

    Article • SLEEP, April 2017, Oxford University Press (OUP)

    Frank A.J.L. Scheer

  103. 0063 UNEXPECTED INCREASE IN MELATONIN CONCENTRATIONS DURING DAYTIME SLEEP IN SIMULATED NIGHT WORK PROTOCOL

    Article • SLEEP, April 2017, Oxford University Press (OUP)

    Frank A.J.L. Scheer

  104. 1013 SHIFT WORK, CHRONOTYPE, AND TYPE 2 DIABETES IN THE UK BIOBANK AND TYPE 2 DIABETES IN THE UK BIOBANK

    Article • SLEEP, April 2017, Oxford University Press (OUP)

    Frank A.J.L. Scheer

  105. The Relative Impact of Sleep and Circadian Drive on Motor Skill Acquisition and Memory Consolidation

    Article • SLEEP, April 2017, Oxford University Press (OUP)

    Frank A.J.L. Scheer

  106. Circadian Misalignment Increases C-Reactive Protein and Blood Pressure in Chronic Shift Workers

    Article • Journal of Biological Rhythms, March 2017, SAGE Publications

    Frank A.J.L. Scheer

  107. National Sleep Foundation's sleep quality recommendations: first report

    Article • Sleep Health, February 2017, Elsevier

    Frank A.J.L. Scheer

  108. Genome-wide association analyses of sleep disturbance traits identify new loci and highlight shared genetics with neuropsychiatric and metabolic traits

    Article • Nature Genetics, December 2016, Springer Science + Business Media

    Frank A.J.L. Scheer

  109. Timing of food intake is associated with weight loss evolution in severe obese patients after bariatric surgery

    Article • Clinical Nutrition, December 2016, Elsevier

    Frank A.J.L. Scheer

  110. Genome-wide association analyses of sleep disturbance traits identify new loci and highlight shared genetics with neuropsychiatric and metabolic traits

    Article • October 2016, Cold Spring Harbor Laboratory Press

    Frank A.J.L. Scheer

  111. Demonstration of a day-night rhythm in human skeletal muscle oxidative capacity

    Article • Molecular Metabolism, August 2016, Elsevier

    Frank A.J.L. Scheer

  112. Human adipose tissue expresses intrinsic circadian rhythm in insulin sensitivity

    Article • The FASEB Journal, June 2016, Federation of American Societies For Experimental Biology (FASEB)

    PhD Olga Martínez Augustin, Marta Garaulet, Frank A.J.L. Scheer

  113. Progression of Dementia Assessed by Temporal Correlations of Physical Activity: Results From a 3.5-Year, Longitudinal Randomized Controlled Trial

    Article • Scientific Reports, June 2016, Springer Science + Business Media

    Frank A.J.L. Scheer, Steven A Shea

  114. Circadian System and Glucose Metabolism: Implications for Physiology and Disease

    Article • Trends in Endocrinology and Metabolism, May 2016, Elsevier

    Frank A.J.L. Scheer

  115. Circadian gene variants influence sleep and the sleep electroencephalogram in humans

    Article • Chronobiology International, April 2016, Taylor & Francis

    Frank A.J.L. Scheer, Steven A Shea

  116. Genome-wide association analysis identifies novel loci for chronotype in 100,420 individuals from the UK Biobank

    Article • Nature Communications, March 2016, Springer Science + Business Media

    Frank A.J.L. Scheer

  117. Circadian Rhythms, Metabolism, and Chrononutrition in Rodents and Humans

    Article • Advances in Nutrition, March 2016, Oxford University Press (OUP)

    Frank A.J.L. Scheer

  118. Effects of the Internal Circadian System and Circadian Misalignment on Glucose Tolerance in Chronic Shift Workers

    Article • The Journal of Clinical Endocrinology & Metabolism, March 2016, Endocrine Society

    Frank A.J.L. Scheer

  119. Hungry for Sleep: A Role for Endocannabinoids?

    Article • SLEEP, March 2016, Oxford University Press (OUP)

    Frank A.J.L. Scheer

  120. T2D risk variant in MTNR1B linked to melatonin, sleep, and circadian traits.

    Article • Diabetes, February 2016, American Diabetes Association

    Steven A Shea, Frank A.J.L. Scheer

  121. Actigraphic sleep fragmentation, efficiency and duration associate with dietary intake in the Rotterdam Study

    Article • Journal of Sleep Research, February 2016, Wiley

    Dr Trudy Voortman, Frank A.J.L. Scheer

  122. Circadian misalignment increases cardiovascular disease risk factors in humans

    Article • Proceedings of the National Academy of Sciences, February 2016, Proceedings of the National Academy of Sciences

    Frank A.J.L. Scheer

  123. Genome-wide association analysis identifies novel loci for chronotype in 100,420 individuals from the UKBiobank

    Article • February 2016, Cold Spring Harbor Laboratory Press

    Frank A.J.L. Scheer

  124. Common type 2 diabetes risk variant in MTNR1B worsens the deleterious effect of melatonin on glucose tolerance in humans

    Article • Metabolism, December 2015, Elsevier

    Frank A.J.L. Scheer

  125. Impact of Sleep and Circadian Disruption on Energy Balance and Diabetes: A Summary of Workshop Discussions

    Article • SLEEP, December 2015, Oxford University Press (OUP)

    Frank A.J.L. Scheer

  126. Short Sleep Duration and Dietary Intake: Epidemiologic Evidence, Mechanisms, and Health Implications

    Article • Advances in Nutrition, November 2015, Oxford University Press (OUP)

    Frank A.J.L. Scheer

  127. The Human Circadian System Has a Dominating Role in Causing the Morning/Evening Difference in Diet-Induced Thermogenesis

    Article • Obesity, September 2015, Wiley

    Frank A.J.L. Scheer

  128. Endogenous circadian regulation of pro-inflammatory cytokines and chemokines in the presence of bacterial lipopolysaccharide in humans

    Article • Brain Behavior and Immunity, July 2015, Elsevier

    Frank A.J.L. Scheer, Steven A Shea

  129. Gene-Environment Interactions of Circadian-Related Genes for Cardiometabolic Traits

    Article • Diabetes Care, June 2015, American Diabetes Association

    Dr Jessica C Kiefte-de Jong, Jari Lahti, Frank A.J.L. Scheer

  130. Clock Genes Explain a Large Proportion of Phenotypic Variance in Systolic Blood Pressure and This Control Is Not Modified by Environmental Temperature

    Article • American Journal of Hypertension, June 2015, Oxford University Press (OUP)

    Professor Katherine L Tucker, Frank A.J.L. Scheer

  131. Endogenous circadian system and circadian misalignment impact glucose tolerance via separate mechanisms in humans

    Article • Proceedings of the National Academy of Sciences, April 2015, Proceedings of the National Academy of Sciences

    Steven A Shea, Frank A.J.L. Scheer

  132. Sleep inertia, sleep homeostatic and circadian influences on higher-order cognitive functions

    Article • Journal of Sleep Research, March 2015, Wiley

    Frank A.J.L. Scheer

  133. Lack of exercise leads to significant and reversible loss of scale invariance in both aged and young mice

    Article • Proceedings of the National Academy of Sciences, February 2015, Proceedings of the National Academy of Sciences

    Frank A.J.L. Scheer

  134. Habitual sleep duration is associated with BMI and macronutrient intake and may be modified by CLOCK genetic variants

    Article • American Journal of Clinical Nutrition, November 2014, Oxford University Press (OUP)

    Professor Timo Partonen, Jari Lahti, Frank A.J.L. Scheer

  135. Meal frequency and timing in health and disease

    Article • Proceedings of the National Academy of Sciences, November 2014, Proceedings of the National Academy of Sciences

    Frank A.J.L. Scheer

  136. Meal timing affects glucose tolerance, substrate oxidation and circadian-related variables: A randomized, crossover trial

    Article • International Journal of Obesity, October 2014, Springer Science + Business Media

    Frank A.J.L. Scheer

  137. Acute Melatonin Administration in Humans Impairs Glucose Tolerance in Both the Morning and Evening

    Article • SLEEP, October 2014, Oxford University Press (OUP)

    Frank A.J.L. Scheer

  138. Metabolic effects of sleep disruption, links to obesity and diabetes

    Article • Current Opinion in Endocrinology Diabetes and Obesity, August 2014, Wolters Kluwer Health

    Frank A.J.L. Scheer

  139. Simulated shift work in rats perturbs multiscale regulation of locomotor activity

    Article • Journal of The Royal Society Interface, May 2014, Royal Society Publishing

    Dr Wan-Hsin Hsieh, Frank A.J.L. Scheer, Steven A Shea

  140. The suprachiasmatic nucleus is part of a neural feedback circuit adapting blood pressure response

    Article • Neuroscience, April 2014, Elsevier

    Frank A.J.L. Scheer

  141. Common Variants in CLOCK Are Not Associated with Measures of Sleep Duration in People of European Ancestry from the Sleep Heart Health Study

    Article • Biological Psychiatry, December 2013, Elsevier

    Frank A.J.L. Scheer

  142. Sleep duration does not mediate or modify association of common genetic variants with type 2 diabetes

    Article • Diabetologia, November 2013, Springer Science + Business Media

    Frank A.J.L. Scheer

  143. Human circadian system causes a morning peak in prothrombotic plasminogen activator inhibitor-1 (PAI-1) independent of the sleep/wake cycle

    Article • Blood, November 2013, American Society of Hematology

    Steven A Shea, Frank A.J.L. Scheer

  144. Direct Effects of Light on Alertness, Vigilance, and the Waking Electroencephalogram in Humans Depend on Prior Light History

    Article • SLEEP, August 2013, Oxford University Press (OUP)

    Frank A.J.L. Scheer

  145. Noninvasive fractal biomarker of clock neurotransmitter disturbance in humans with dementia

    Article • Scientific Reports, July 2013, Springer Science + Business Media

    Steven A Shea, Frank A.J.L. Scheer

  146. Alterations of melatonin receptors MT1 and MT2 in the hypothalamic suprachiasmatic nucleus during depression

    Article • Journal of Affective Disorders, June 2013, Elsevier

    Frank A.J.L. Scheer

  147. The role of the circadian system in fractal neurophysiological control

    Article • Biological Reviews, April 2013, Wiley

    Steven A Shea, Frank A.J.L. Scheer

  148. Day/Night Variability in Blood Pressure: Influence of Posture and Physical Activity

    Article • American Journal of Hypertension, March 2013, Oxford University Press (OUP)

    Frank A.J.L. Scheer

  149. The internal circadian clock increases hunger and appetite in the evening independent of food intake and other behaviors

    Article • Obesity, March 2013, Wiley

    Steven A Shea, Frank A.J.L. Scheer

  150. Timing of food intake predicts weight loss effectiveness

    Article • International Journal of Obesity, January 2013, Springer Science + Business Media

    Frank A.J.L. Scheer

  151. Fractal Patterns of Neural Activity Exist within the Suprachiasmatic Nucleus and Require Extrinsic Network Interactions

    Article • PLoS ONE, November 2012, PLOS

    Steven A Shea, Frank A.J.L. Scheer

  152. Repeated Melatonin Supplementation Improves Sleep in Hypertensive Patients Treated with Beta-Blockers: A Randomized Controlled Trial

    Article • SLEEP, October 2012, Associated Professional Sleep Societies (APSS)

    Steven A Shea, Frank A.J.L. Scheer

  153. Klf15 Orchestrates Circadian Nitrogen Homeostasis

    Article • Cell Metabolism, March 2012, Elsevier

    Steven A Shea, Frank A.J.L. Scheer

  154. Circadian system, sleep and endocrinology

    Article • Molecular and Cellular Endocrinology, February 2012, Elsevier

    Frank A.J.L. Scheer

  155. The impact of the circadian timing system on cardiovascular and metabolic function

    Article • January 2012, Elsevier

    Frank A.J.L. Scheer

  156. Response to Letter Regarding Article, “Endogenous Circadian Rhythm in Vasovagal Response to Head-Up Tilt”

    Article • Circulation, September 2011, Wolters Kluwer Health

    Steven A Shea, Frank A.J.L. Scheer

  157. The Human Endogenous Circadian System Causes Greatest Platelet Activation during the Biological Morning Independent of Behaviors

    Article • PLoS ONE, September 2011, PLOS

    Steven A Shea, Frank A.J.L. Scheer

  158. Existence of an Endogenous Circadian Blood Pressure Rhythm in Humans That Peaks in the Evening

    Article • Circulation Research, April 2011, Wolters Kluwer Health

    Steven A Shea, Frank A.J.L. Scheer

  159. Circadian disruption and SCN control of energy metabolism

    Article • FEBS Letters, March 2011, Wiley

    Andries Kalsbeek, Frank A.J.L. Scheer

  160. Endogenous Circadian Rhythm in Vasovagal Response to Head-Up Tilt

    Article • Circulation, March 2011, Wolters Kluwer Health

    Steven A Shea, Frank A.J.L. Scheer

  161. The human circadian system adapts to prior photic history

    Article • The Journal of Physiology, February 2011, Wiley

    Frank A.J.L. Scheer

  162. Impact of the human circadian system, exercise, and their interaction on cardiovascular function

    Article • Proceedings of the National Academy of Sciences, November 2010, Proceedings of the National Academy of Sciences

    Steven A Shea, Frank A.J.L. Scheer

  163. Day/night variations of high-molecular-weight adiponectin and lipocalin-2 in healthy men studied under fed and fasted conditions

    Article • Diabetologia, August 2010, Springer Science + Business Media

    Frank A.J.L. Scheer, Steven A Shea

  164. Acute Effects of Bright Light Exposure on Cortisol Levels

    Article • Journal of Biological Rhythms, May 2010, SAGE Publications

    Frank A.J.L. Scheer

  165. Is there a circadian variation of epileptiform abnormalities in idiopathic generalized epilepsy?

    Article • Epilepsy & Behavior, November 2009, Elsevier

    Steven A Shea, Frank A.J.L. Scheer

  166. Effects of circadian disruption on the cardiometabolic system

    Article • Reviews in Endocrine and Metabolic Disorders, September 2009, Springer Science + Business Media

    Frank A.J.L. Scheer

  167. Influence of the Circadian System on Disease Severity

    Article • Sleep Medicine Clinics, June 2009, Elsevier

    Steven A Shea, Frank A.J.L. Scheer

  168. Adverse metabolic and cardiovascular consequences of circadian misalignment

    Article • Proceedings of the National Academy of Sciences, March 2009, Proceedings of the National Academy of Sciences

    Steven A Shea, Frank A.J.L. Scheer

  169. Reduction of scale invariance of activity fluctuations with aging and Alzheimer's disease: Involvement of the circadian pacemaker

    Article • Proceedings of the National Academy of Sciences, February 2009, Proceedings of the National Academy of Sciences

    Steven A Shea, Frank A.J.L. Scheer

  170. An Endogenous Circadian Rhythm in Sleep Inertia Results in Greatest Cognitive Impairment upon Awakening during the Biological Night

    Article • Journal of Biological Rhythms, August 2008, SAGE Publications

    Steven A Shea, Frank A.J.L. Scheer

  171. The circadian pacemaker generates similar circadian rhythms in the fractal structure of heart rate in humans and rats

    Article • Cardiovascular Research, June 2008, European Society of Cardiology

    Steven A Shea, Frank A.J.L. Scheer

  172. The Endogenous Circadian Pacemaker Imparts a Scale-Invariant Pattern of Heart Rate Fluctuations across Time Scales Spanning Minutes to 24 Hours

    Article • Journal of Biological Rhythms, June 2008, SAGE Publications

    Steven A Shea, Frank A.J.L. Scheer

  173. The suprachiasmatic nucleus functions beyond circadian rhythm generation

    Article • Neuroscience, November 2007, Elsevier

    Steven A Shea, Frank A.J.L. Scheer

  174. Plasticity of the Intrinsic Period of the Human Circadian Timing System

    Article • PLoS ONE, August 2007, PLOS

    Frank A.J.L. Scheer

  175. Decreased Sleep in Heart Failure: Are Medications to Blame?

    Article • Archives of Internal Medicine, May 2007, American Medical Association (AMA)

    Frank A.J.L. Scheer, Steven A Shea

  176. SCN Outputs and the Hypothalamic Balance of Life

    Article • Journal of Biological Rhythms, December 2006, SAGE Publications

    Andries Kalsbeek, Frank A.J.L. Scheer

  177. Organization of circadian functions: interaction with the body

    Article • January 2006, Elsevier

    Andries Kalsbeek, Frank A.J.L. Scheer

  178. Potential Use of Melatonin as Adjunct Antihypertensive Therapy

    Article • American Journal of Hypertension, December 2005, Oxford University Press (OUP)

    Frank A.J.L. Scheer

  179. Reduced sleep efficiency in cervical spinal cord injury; association with abolished night time melatonin secretion

    Article • Spinal Cord, August 2005, Springer Science + Business Media

    Dr Jamie Zeitzer, Steven A Shea, Frank A.J.L. Scheer

  180. Melatonin, sleep, and circadian rhythms

    Article • Sleep Medicine Reviews, February 2005, Elsevier

    Frank A.J.L. Scheer

  181. Environmental light and suprachiasmatic nucleus interact in the regulation of body temperature

    Article • Neuroscience, January 2005, Elsevier

    Frank A.J.L. Scheer

  182. Melatonin in the Regulation of Sleep and Circadian Rhythms

    Article • January 2005, Elsevier

    Frank A.J.L. Scheer

  183. Daily Nighttime Melatonin Reduces Blood Pressure in Male Patients With Essential Hypertension

    Article • Hypertension, February 2004, Wolters Kluwer Health

    Frank A.J.L. Scheer

  184. Light and diurnal cycle affect autonomic cardiac balance in human; possible role for the biological clock

    Article • Autonomic Neuroscience, January 2004, Elsevier

    Frank A.J.L. Scheer

  185. Cardiovascular Control by the Suprachiasmatic Nucleus: Neural and Neuroendocrine Mechanisms in Human and Rat

    Article • Biological Chemistry, January 2003, De Gruyter

    Andries Kalsbeek, Frank A.J.L. Scheer

  186. Human basal cortisol levels are increased in hospital compared to home setting

    Article • Neuroscience Letters, November 2002, Elsevier

    Frank A.J.L. Scheer

  187. Physiological and anatomic evidence for regulation of the heart by suprachiasmatic nucleus in rats

    Article • AJP Heart and Circulatory Physiology, March 2001, American Physiological Society

    Frank A.J.L. Scheer

  188. Circadian Organization of the Autonomic Nervous System

    Article • January 2000, Springer Science + Business Media

    Andries Kalsbeek, Frank A.J.L. Scheer

  189. Light Affects Morning Salivary Cortisol in Humans

    Article • The Journal of Clinical Endocrinology & Metabolism, September 1999, Endocrine Society

    Frank A.J.L. Scheer

  190. Light Affects Morning Salivary Cortisol in Humans

    Article • The Journal of Clinical Endocrinology & Metabolism, September 1999, Endocrine Society

    Frank A.J.L. Scheer

  191. Light and Diurnal Cycle Affect Human Heart Rate: Possible Role for the Circadian Pacemaker

    Article • Journal of Biological Rhythms, June 1999, SAGE Publications

    Frank A.J.L. Scheer