All Stories

  1. Nucleophilic radiofluorination at room temperature via aziridinium intermediates

    Article • RSC Advances, January 2014, Royal Society of Chemistry

    Dr Franck Sobrio

  2. Radiosynthesis of carbon‐11 and fluorine‐18 labelled radiotracers to image the ionotropic and metabotropic glutamate receptors

    Article • Journal of Labelled Compounds and Radiopharmaceuticals, March 2013, Wiley

    Dr Franck Sobrio

  3. A new class of fluorinated 5-pyrrolidinylsulfonyl isatin caspase inhibitors for PET imaging of apoptosis

    Article • MedChemComm, January 2013, Royal Society of Chemistry

    Dr Franck Sobrio

  4. Automated Radiosynthesis of [18F]ML-10, a PET Radiotracer Dedicated to Apoptosis Imaging, on a TRACERLab FX-FN Module

    Article • Molecular Imaging and Biology, July 2012, Springer Science + Business Media

    Dr Franck Sobrio

  5. Synthesis and in vitro characterization of trans- and cis-[18F]-4-methylbenzyl 4-[(pyrimidin-2-ylamino)methyl]-3-fluoropiperidine-1-carboxylates as new potential PET radiotracer candidates for the NR2B subtype N-methyl-d-aspartate receptor

    Article • European Journal of Medicinal Chemistry, July 2012, Elsevier

    Dr Franck Sobrio

  6. Radiolabelling of 1,4-disubstituted 3-[18F]fluoropiperidines and its application to new radiotracers for NR2B NMDA receptor visualization

    Article • Organic & Biomolecular Chemistry, January 2012, Royal Society of Chemistry

    Dr Franck Sobrio

  7. Synthesis, evaluation and metabolic studies of radiotracers containing a 4-(4-[18F]-fluorobenzyl)piperidin-1-yl moiety for the PET imaging of NR2B NMDA receptors

    Article • European Journal of Medicinal Chemistry, June 2011, Elsevier

    Dr Franck Sobrio

  8. Complementary information from magnetic resonance imaging and 18F-fluoromisonidazole positron emission tomography in the assessment of the response to an antiangiogenic treatment in a rat brain tumor model

    Article • Nuclear Medicine and Biology, April 2011, Elsevier

    Dr Franck Sobrio

  9. PET and SPECT Imaging of the NMDA Receptor System: An Overview of Radiotracer Development

    Article • Mini-Reviews in Medicinal Chemistry, August 2010, Bentham Science Publishers

    Dr Franck Sobrio

  10. Efficient Radiosynthesis of 2-[18F]Fluoroadenosine: A New Route to 2-[18F]Fluoropurine Nucleosides

    Article • ACS Medicinal Chemistry Letters, May 2010, American Chemical Society (ACS)

    Dr Franck Sobrio

  11. Simultaneous tritium labelling of two potent 5-HT4 ligands

    Article • European Journal of Medicinal Chemistry, March 2010, Elsevier

    Dr Franck Sobrio

  12. Radiosynthesis of N‐[4‐(4‐fluorobenzyl)piperidin‐1‐yl]‐N′‐(2‐[11C]oxo‐1,3‐dihydrobenzimidazol‐5‐yl)oxamide, a NR2B‐selective NMDA receptor antagonist

    Article • Journal of Labelled Compounds and Radiopharmaceuticals, December 2009, Wiley

    Dr Franck Sobrio

  13. Radiosynthesis and ex vivo evaluation of [11C]-SIB-1553A as a PET radiotracer for β4 selective subtype nicotinic acetylcholine receptor

    Article • Nuclear Medicine and Biology, April 2008, Elsevier

    Dr Franck Sobrio

  14. Tetra- and Monoorganotin Reagents in Palladium-Mediated Cross-Coupling Reactions for the Labeling with Carbon-11 of PET Tracers

    Article • Synthesis, March 2008, Thieme Publishing Group

    Dr Franck Sobrio

  15. Methyl transfer reaction from monomethyltin reagent under palladium(0) catalysis: a versatile method for labelling with carbon-11

    Article • Chemical Communications, January 2006, Royal Society of Chemistry

    Dr Franck Sobrio

  16. Efficiency of 18F-FDG and 99mTc-depreotide SPECT in the diagnosis of malignancy of solitary pulmonary nodules

    Article • European Journal of Nuclear Medicine and Molecular Imaging, May 2005, Springer Science + Business Media

    Dr Franck Sobrio

  17. Evaluation in rats and primates of [11C]-mecamylamine, a potential nicotinic acetylcholine receptor radioligand for positron emission tomography

    Article • Neurochemistry International, May 2005, Elsevier

    Dr Franck Sobrio

  18. Efficiency of [ 18 F]FDG PET in characterising renal cancer and detecting distant metastases: a comparison with CT

    Article • European Journal of Nuclear Medicine and Molecular Imaging, September 2003, Springer Science + Business Media

    Dr Franck Sobrio

  19. Debenzylation of Tertiary Amines Using Phosgene or Triphosgene:  An Efficient and Rapid Procedure for the Preparation of Carbamoyl Chlorides and Unsymmetrical Ureas. Application in Carbon-11 Chemistry

    Article • The Journal of Organic Chemistry, August 2003, American Chemical Society (ACS)

    Dr Franck Sobrio

  20. Short-term pharmacokinetics and brain distribution of mecamylamine as a preliminary to carbon-11 labeling for nicotinic receptor investigation

    Article • Journal of Pharmaceutical Sciences, May 2003, Elsevier

    Dr Franck Sobrio

  21. Total synthesis and radiolabelling of an efficient rt-PA inhibitor: [11C] (Z,Z)-BABCH. A first route to [11C] labelled amidines

    Article • Journal of the Chemical Society Perkin Transactions 1, January 2001, Royal Society of Chemistry

    Dr Franck Sobrio

  22. Radiosynthesis of [18F]Lu29-024: A potential PET ligand for brain imaging of the serotonergic 5-HT2 receptor

    Article • Bioorganic & Medicinal Chemistry, October 2000, Elsevier

    Dr Franck Sobrio

  23. Functional Characterization of a New Class of Odorant-Binding Proteins in the MothMamestra brassicae

    Article • Biochemical and Biophysical Research Communications, December 1998, Elsevier

    Dr Franck Sobrio

  24. Synthesis of [3H2]-21-diazoprogesterone as a potent photoaffinity labelling reagent for the mineralocorticoid receptor

    Article • Journal of Labelled Compounds and Radiopharmaceuticals, October 1997, Wiley

    Dr Franck Sobrio

  25. Mechanism‐Based Inactivation of Bovine Cytochrome P‐450U11β by 18‐Unsaturated Progesterone Derivatives

    Article • European Journal of Biochemistry, August 1997, Wiley

    Dr Franck Sobrio

  26. Pheromone binding proteins of the moth Mamestra brassicae: Specificity of ligand binding

    Article • Insect Biochemistry and Molecular Biology, March 1997, Elsevier

    Dr Franck Sobrio

  27. Synthesis and purification of highly tritiated aryldiazonium photoprobes for cholinergic binding sites

    Article • Journal of Labelled Compounds and Radiopharmaceuticals, June 1996, Wiley

    Dr Franck Sobrio

  28. The mineralocorticoid activity of progesterone derivatives depends on the nature of the C18 substituent.

    Article • Endocrinology, December 1995, Endocrine Society

    Dr Franck Sobrio, Elisabeth Davioud-Charvet

  29. Synthesis of high specific radioactivity [3H]emodin

    Article • Journal of Labelled Compounds and Radiopharmaceuticals, August 1995, Wiley

    Dr Franck Sobrio

  30. Labelling of brefeldin‐a by catalyzed isotopic exchange with tritium gas

    Article • Journal of Labelled Compounds and Radiopharmaceuticals, September 1994, Wiley

    Dr Franck Sobrio

  31. Synthesis of a tritiated 3-dehydroecdysteroid putative precursor of ecdysteroid biosynthesis

    Article • Tetrahedron, March 1993, Elsevier

    Dr Franck Sobrio