All Stories

  1. An interstrand DNA crosslink glycosylase aids Acinetobacter baumannii pathogenesis

    Article • Proceedings of the National Academy of Sciences, June 2024, Proceedings of the National Academy of Sciences

    Dr Eric P Skaar

  2. Lipocalin-2 is an essential component of the innate immune response to Acinetobacter baumannii infection

    Article • PLoS Pathogens, September 2022, PLOS

    Dr Eric P Skaar

  3. Directed evolution reveals the mechanism of HitRS signaling transduction in Bacillus anthracis

    Article • PLoS Pathogens, December 2020, PLOS

    Dr Eric P Skaar

  4. Acinetobacter baumannii can use multiple siderophores for iron acquisition, but only acinetobactin is required for virulence

    Article • PLoS Pathogens, October 2020, PLOS

    Dr Eric P Skaar

  5. Broad-spectrum suppression of bacterial pneumonia by aminoglycoside-propagated Acinetobacter baumannii

    Article • PLoS Pathogens, March 2020, PLOS

    Dr Eric P Skaar

  6. Molecular Basis for the Evolution of Species-Specific Hemoglobin Capture by Staphylococcus aureus

    Article • mBio, November 2018, ASM Journals

    Dr Eric P Skaar

  7. The role of zinc and nutritional immunity in Clostridium difficile infection

    Article • Gut Microbes, March 2018, Taylor & Francis

    Dr Eric P Skaar

  8. Staphylococcus aureus HemX Modulates Glutamyl-tRNA Reductase Abundance To Regulate Heme Biosynthesis

    Article • mBio, February 2018, ASM Journals

    Dr Eric P Skaar

  9. Chlamydomonas reinhardtii LFO1 Is an IsdG Family Heme Oxygenase

    Article • mSphere, August 2017, ASM Journals

    Dr Eric P Skaar, Professor Antonis Rokas

  10. Mechanisms of Pyocyanin Toxicity and Genetic Determinants of Resistance in Staphylococcus aureus

    Article • Journal of Bacteriology, June 2017, ASM Journals

    Dr Eric P Skaar

  11. RAGE-Mediated Suppression of Interleukin-10 Results in Enhanced Mortality in a Murine Model of Acinetobacter baumannii Sepsis

    Article • Infection and Immunity, January 2017, ASM Journals

    Dr Eric P Skaar

  12. Acinetobacter baumannii Coordinates Urea Metabolism with Metal Import To Resist Host-Mediated Metal Limitation

    Article • mBio, September 2016, ASM Journals

    Dr Eric P Skaar

  13. CtaM Is Required for Menaquinol Oxidaseaa3Function inStaphylococcus aureus

    Article • mBio, July 2016, ASM Journals

    Dr Eric P Skaar

  14. Toll-Like Receptor 9 Contributes to Defense against Acinetobacter baumannii Infection

    Article • Infection and Immunity, August 2015, ASM Journals

    Dr Eric P Skaar

  15. An Iron-Regulated Autolysin Remodels the Cell Wall To Facilitate Heme Acquisition in Staphylococcus lugdunensis

    Article • Infection and Immunity, June 2015, ASM Journals

    Dr Eric P Skaar

  16. A New Family of Secreted Toxins in Pathogenic Neisseria Species

    Article • PLoS Pathogens, January 2015, PLOS

    Dr Eric P Skaar, Dr Anne JAMET

  17. Metals in infectious diseases and nutritional immunity

    Article • Metallomics, January 2015, Oxford University Press (OUP)

    Dr Eric P Skaar, Manuela Raffatellu

  18. Nfu facilitates the maturation of iron-sulfur proteins and participates in virulence inStaphylococcus aureus

    Article • Molecular Microbiology, December 2014, Wiley

    Dr Eric P Skaar

  19. The CsoR‐like sulfurtransferase repressor (CstR) is a persulfide sensor in Staphylococcus aureus

    Article • Molecular Microbiology, November 2014, Wiley

    Dr Eric P Skaar

  20. Metal limitation and toxicity at the interface between host and pathogen

    Article • FEMS Microbiology Reviews, November 2014, Oxford University Press (OUP)

    Dr Eric P Skaar

  21. The Host Protein Calprotectin Modulates the Helicobacter pylori cag Type IV Secretion System via Zinc Sequestration

    Article • PLoS Pathogens, October 2014, PLOS

    Dr Eric P Skaar, Dr Timothy L Cover

  22. Inter- and Intraspecies Metabolite Exchange Promotes Virulence of Antibiotic-Resistant Staphylococcus aureus

    Article • Cell Host & Microbe, October 2014, Elsevier

    Dr Eric P Skaar

  23. Advanced mass spectrometry technologies for the study of microbial pathogenesis

    Article • Current Opinion in Microbiology, June 2014, Elsevier

    Dr Eric P Skaar

  24. Acinetobacter baumannii Response to Host-Mediated Zinc Limitation Requires the Transcriptional Regulator Zur

    Article • Journal of Bacteriology, May 2014, ASM Journals

    Dr Eric P Skaar

  25. Two-Component System Cross-Regulation Integrates Bacillus anthracis Response to Heme and Cell Envelope Stress

    Article • PLoS Pathogens, March 2014, PLOS

    Dr Eric P Skaar

  26. Structure and Function of the Genomically Encoded Fosfomycin Resistance Enzyme, FosB, from Staphylococcus aureus

    Article • Biochemistry, January 2014, American Chemical Society (ACS)

    Dr Eric P Skaar

  27. Differential Activation of Staphylococcus aureus Heme Detoxification Machinery by Heme Analogues

    Article • Journal of Bacteriology, January 2014, ASM Journals

    Dr Eric P Skaar

  28. Recent advances in experimental models of osteomyelitis

    Article • Expert Review of Anti-infective Therapy, December 2013, Taylor & Francis

    Dr Eric P Skaar

  29. Heme and Infectious Diseases

    Article • October 2013, World Scientific Pub Co Pte Lt

    Dr Eric P Skaar

  30. Regulation of Host Hemoglobin Binding by the Staphylococcus aureus Clp Proteolytic System

    Article • Journal of Bacteriology, August 2013, ASM Journals

    Dr Eric P Skaar

  31. Two Heme-Dependent Terminal Oxidases Power Staphylococcus aureus Organ-Specific Colonization of the Vertebrate Host

    Article • mBio, July 2013, ASM Journals

    Dr Eric P Skaar

  32. A Product of Heme Catabolism Modulates Bacterial Function and Survival

    Article • PLoS Pathogens, July 2013, PLOS

    Dr Eric P Skaar

  33. Imaging mass spectrometry for assessing temporal proteomics: Analysis of calprotectin inAcinetobacter baumanniipulmonary infection

    Article • PROTEOMICS, July 2013, Wiley

    Dr Eric P Skaar

  34. MntABC and MntH Contribute to Systemic Staphylococcus aureus Infection by Competing with Calprotectin for Nutrient Manganese

    Article • Infection and Immunity, July 2013, ASM Journals

    Dr Eric P Skaar

  35. Analysis of the Staphylococcus aureus abscess proteome identifies antimicrobial host proteins and bacterial stress responses at the host-pathogen interface

    Article • Pathogens and Disease, July 2013, Oxford University Press (OUP)

    Dr Eric P Skaar

  36. A Secreted Bacterial Protease Tailors the Staphylococcus aureus Virulence Repertoire to Modulate Bone Remodeling during Osteomyelitis

    Article • Cell Host & Microbe, June 2013, Elsevier

    Dr Eric P Skaar

  37. Iron in Infection and Immunity

    Article • Cell Host & Microbe, May 2013, Elsevier

    Dr Eric P Skaar

  38. Powerful Genetic Resource for the Study of Methicillin-Resistant Staphylococcus aureus

    Article • mBio, April 2013, ASM Journals

    Dr Eric P Skaar

  39. Staphylococcus aureus Growth using Human Hemoglobin as an Iron Source

    Article • Journal of Visualized Experiments, February 2013, MyJove Corporation

    Dr Eric P Skaar

  40. Genomic and Functional Analysis of the Type VI Secretion System in Acinetobacter

    Article • PLoS ONE, January 2013, PLOS

    Dr Eric P Skaar

  41. The contribution of nutrient metal acquisition and metabolism to Acinetobacter baumannii survival within the host

    Article • Frontiers in Cellular and Infection Microbiology, January 2013, Frontiers

    Dr Eric P Skaar

  42. Genetic Determinants of Intrinsic Colistin Tolerance in Acinetobacter baumannii

    Article • Infection and Immunity, December 2012, ASM Journals

    Dr Eric P Skaar

  43. Identification of an Acinetobacter baumannii Zinc Acquisition System that Facilitates Resistance to Calprotectin-mediated Zinc Sequestration

    Article • PLoS Pathogens, December 2012, PLOS

    Dr Eric P Skaar

  44. Menaquinone biosynthesis potentiates haem toxicity in Staphylococcus aureus

    Article • Molecular Microbiology, October 2012, Wiley

    Dr Eric P Skaar

  45. Nutritional immunity: transition metals at the pathogen–host interface

    Article • Nature Reviews Microbiology, July 2012, Springer Science + Business Media

    Dr Eric P Skaar

  46. Host-microbe interactions that shape the pathogenesis ofAcinetobacter baumanniiinfection

    Article • Cellular Microbiology, June 2012, Hindawi Publishing Corporation

    Dr Eric P Skaar

  47. Monitoring the Inflammatory Response to Infection through the Integration of MALDI IMS and MRI

    Article • Cell Host & Microbe, June 2012, Elsevier

    Dr Eric P Skaar

  48. Inhibition of bacterial superoxide defense

    Article • Virulence, May 2012, Taylor & Francis

    Dr Eric P Skaar

  49. Metalloregulation of Gram-positive pathogen physiology

    Article • Current Opinion in Microbiology, April 2012, Elsevier

    Dr Eric P Skaar

  50. Taste for Blood: Hemoglobin as a Nutrient Source for Pathogens

    Article • PLoS Pathogens, March 2012, PLOS

    Dr Eric P Skaar

  51. A battle for iron: host sequestration and Staphylococcus aureus acquisition

    Article • Microbes and Infection, March 2012, Elsevier

    Dr Eric P Skaar

  52. Zinc Sequestration by the Neutrophil Protein Calprotectin Enhances Salmonella Growth in the Inflamed Gut

    Article • Cell Host & Microbe, March 2012, Elsevier

    Dr Eric P Skaar, Manuela Raffatellu

  53. The impact of metal sequestration on Staphylococcus aureus metabolism

    Article • Current Opinion in Microbiology, February 2012, Elsevier

    Dr Eric P Skaar

  54. The Molecular Basis for Calprotectin Function in Nutritional Immunity

    Article • Annals of Paediatric Rheumatology, January 2012, ScopeMed International Medical Journal Management and Indexing System

    Dr Eric P Skaar

  55. Metal ion acquisition in Staphylococcus aureus: overcoming nutritional immunity

    Article • Seminars in Immunopathology, November 2011, Springer Science + Business Media

    Dr Eric P Skaar

  56. Molecular Mechanisms ofStaphylococcus aureusIron Acquisition

    Article • Annual Review of Microbiology, October 2011, Annual Reviews

    Dr Eric P Skaar

  57. The evolution of a superbug: how Staphylococcus aureus overcomes its unique susceptibility to polyamines

    Article • Molecular Microbiology, September 2011, Wiley

    Dr Eric P Skaar

  58. Nutrient Metal Sequestration by Calprotectin Inhibits Bacterial Superoxide Defense, Enhancing Neutrophil Killing of Staphylococcus aureus

    Article • Cell Host & Microbe, August 2011, Elsevier

    Dr Eric P Skaar

  59. The Flexible Loop of Staphylococcus aureus IsdG Is Required for Its Degradation in the Absence of Heme

    Article • Biochemistry, July 2011, American Chemical Society (ACS)

    Dr Eric P Skaar

  60. Small Molecule Inhibitors of Staphylococcus aureus RnpA Alter Cellular mRNA Turnover, Exhibit Antimicrobial Activity, and Attenuate Pathogenesis

    Article • PLoS Pathogens, February 2011, PLOS

    Dr Oluwatoyin A Asojo, Dr Eric P Skaar

  61. Specificity for Human Hemoglobin Enhances Staphylococcus aureus Infection

    Article • Cell Host & Microbe, December 2010, Elsevier

    Dr Eric P Skaar, Dr James E Crowe

  62. Iron Acquisition by Bacillus anthracis

    Article • November 2010, Wiley

    Dr Eric P Skaar

  63. The Battle for Iron between Bacterial Pathogens and Their Vertebrate Hosts

    Article • PLoS Pathogens, August 2010, PLOS

    Dr Eric P Skaar

  64. Nutritional immunity beyond iron: a role for manganese and zinc

    Article • Current Opinion in Chemical Biology, April 2010, Elsevier

    Dr Eric P Skaar

  65. Miniature on-chip detection of unpurified methicillin-resistant Staphylococcus aureus (MRSA) DNA using real-time PCR

    Article • Journal of Biotechnology, April 2010, Elsevier

    Dr Eric P Skaar

  66. Membrane Damage Elicits an Immunomodulatory Program in Staphylococcus aureus

    Article • PLoS Pathogens, March 2010, PLOS

    Dr Eric P Skaar

  67. The IsdG‐family of haem oxygenases degrades haem to a novel chromophore

    Article • Molecular Microbiology, March 2010, Wiley

    Dr Eric P Skaar, Michael Murphy

  68. Assessing the Contribution of Heme-Iron Acquisition to Staphylococcus aureus Pneumonia Using Computed Tomography

    Article • PLoS ONE, August 2009, PLOS

    Dr Eric P Skaar

  69. A Precious Metal Heist

    Article • Cell Host & Microbe, May 2009, Elsevier

    Dr Eric P Skaar

  70. Bacillus anthracis HssRS signalling to HrtAB regulates haem resistance during infection

    Article • Molecular Microbiology, April 2009, Wiley

    Dr Eric P Skaar

  71. The Heme Sensor System of <i>Staphylococcus aureus</i>

    Article • January 2009, Karger Publishers

    Dr Eric P Skaar

  72. Staphylococcus aureus haem oxygenases are differentially regulated by iron and haem

    Article • Molecular Microbiology, August 2008, Wiley

    Dr Eric P Skaar

  73. Intracellular metalloporphyrin metabolism in Staphylococcus aureus

    Article • BioMetals, March 2007, Springer Science + Business Media

    Dr Eric P Skaar

  74. Staphylococcus aureus Redirects Central Metabolism to Increase Iron Availability

    Article • PLoS Pathogens, August 2006, PLOS

    Dr Eric P Skaar

  75. Iron-regulated surface determinants (Isd) of Staphylococcus aureus: stealing iron from heme

    Article • Microbes and Infection, April 2004, Elsevier

    Dr Eric P Skaar

  76. Recombination, repair and replication in the pathogenic Neisseriae: the 3 R's of molecular genetics of two human‐specific bacterial pathogens

    Article • Molecular Microbiology, November 2003, Wiley

    Dr Eric P Skaar

  77. Recombination, repair and replication in the pathogenic Neisseriae: the 3 R′s of molecular genetics of two human‐specific bacterial pathogens

    Article • Molecular Microbiology, August 2003, Wiley

    Dr Eric P Skaar

  78. The Misidentification of Bacterial Genes as Human cDNAs: Was the Human D-1 Tumor Antigen Gene Acquired from Bacteria?

    Article • Genomics, May 2002, Elsevier

    Dr Eric P Skaar