All Stories

  1. Efficacy and Tolerability of Generic Pirfenidone After Switch from Esbriet® in Idiopathic Pulmonary Fibrosis: A Real-World Observational Study

    Article • February 2026, Springer Science + Business Media

    Professor Enrico M. Clini

  2. Interventions for Hypertrophic Obstructive Cardiomyopathy: Defining the Gold Standard, Assessing Durability, and Guiding Patient Selection

    Article • Medical Sciences, February 2026, MDPI AG

    Professor Enrico M. Clini

  3. Alpha-1 Antitrypsin Deficiency Beyond COPD and Emphysema: A Narrative Review

    Article • Medical Sciences, February 2026, MDPI AG

    Professor Enrico M. Clini

  4. High-flow nasal therapy vs conventional oxygen therapy in mild COVID-19 hypoxaemia: a Bayesian reanalysis of the COVID-HIGH Trial

    Article • Journal of Anesthesia Analgesia and Critical Care, February 2026, Springer Science + Business Media

    Professor Enrico M. Clini

  5. In-hospital testing of NIVPredict - an AI tool for early prediction of non-invasive ventilation outcome in acute respiratory failure

    Article • Critical Care, February 2026, Springer Science + Business Media

    Professor Enrico M. Clini

  6. Physiopathology of Exacerbation of Chronic Obstructive Pulmonary Disease

    Article • Seminars in Respiratory and Critical Care Medicine, February 2026, Thieme Publishing Group

    Professor Enrico M. Clini

  7. Multiperspective ultrasonography in COPD exacerbations: insights into inspiratory muscle recruitment and clinical outcomes. Author’s reply

    Article • European Journal of Internal Medicine, February 2026, Elsevier

    Professor Enrico M. Clini

  8. The forgotten airway: central airway pathology in the ICU

    Article • Frontiers in Medicine, January 2026, Frontiers

    Professor Enrico M. Clini

  9. Idiopathic Pulmonary Fibrosis: Analysis of Predisposing Variants in Patients with Familial Forms

    Article • Biomedicines, January 2026, MDPI AG

    Professor Enrico M. Clini

  10. Genome-wide association for sarcoidosis identifies novel risk loci and genetic heritability in African and European ancestries: a meta-analysis from the Finngen, Million Veteran Program, UK Biobank, and Biobank Japan datasets

    Article • Orphanet Journal of Rare Diseases, December 2025, Springer Science + Business Media

    Professor Enrico M. Clini

  11. Digital twins of acute hypoxemic respiratory failure and sepsis patients suggest potential benefits of bi-level high flow nasal cannula therapy

    Article • Intensive Care Medicine, December 2025, Springer Science + Business Media

    Professor Enrico M. Clini

  12. Stent and Resection Anastomosis in Patients with Complex Tracheal Stenosis: The Stars Retrospective Multicenter Trial

    Article • Interdisciplinary CardioVascular and Thoracic Surgery, December 2025, Oxford University Press (OUP)

    Professor Enrico M. Clini

  13. Ultrasound-based evaluation of inspiratory muscle effort in patients with type 2 respiratory failure secondary to exacerbation of chronic obstructive pulmonary disease

    Article • European Journal of Internal Medicine, December 2025, Elsevier

    Professor Enrico M. Clini

  14. Optimization of intranasal bleomycin dose for effective pulmonary fibrosis induction in mice with minimal animal distress

    Article • BMC Pulmonary Medicine, November 2025, Springer Science + Business Media

    Professor Enrico M. Clini

  15. Evaluating the effect of heart and respiratory rate measurement errors on the ability to predict the outcome of high flow nasal cannula therapy: a multi-centre study

    Article • Critical Care, November 2025, Springer Science + Business Media

    Professor Enrico M. Clini

  16. Predicting and Treating Pulmonary Fibrosis with Proteomic Biomarker Investigations

    Article • Biomedicines, October 2025, MDPI AG

    Professor Enrico M. Clini

  17. Impact of mesenchymal stromal/stem cell infusions on circulating inflammatory biomarkers in COVID-19 patients: analysis of a phase I-IIa trial

    Article • Cytotherapy, September 2025, Elsevier

    Professor Enrico M. Clini

  18. Assessing inspiratory drive and effort in critically ill patients at the bedside

    Article • Critical Care, July 2025, Springer Science + Business Media

    Professor Enrico M. Clini

  19. Early prediction of non-invasive ventilation outcome using the TabPFN machine learning model: a multi-centre validation study

    Article • Intensive Care Medicine, July 2025, Springer Science + Business Media

    Professor Enrico M. Clini

  20. Refining the predictive value of nasal pressure swing in acute hypoxemic respiratory failure management. Author's reply

    Article • European Journal of Internal Medicine, July 2025, Elsevier

    Professor Enrico M. Clini

  21. The use of the MoCA in cognitive impairment for older patients with Chronic Obstructive Pulmonary disease: A preliminary study

    Article • Science Progress, July 2025, SAGE Publications

    Professor Enrico M. Clini

  22. Drug-Induced Sarcoid-like Reactions Associated to Targeted Therapies and Biologic Agents

    Article • Diagnostics, June 2025, MDPI AG

    Professor Enrico M. Clini

  23. Digital twins suggest a mechanistic basis for differing responses to increased flow rates during high-flow nasal cannula therapy

    Article • Intensive Care Medicine Experimental, June 2025, Springer Science + Business Media

    Professor Enrico M. Clini

  24. Assessment of nasal pressure swing predicts respiratory support dependency in patients with hypoxic respiratory failure

    Article • European Journal of Internal Medicine, May 2025, Elsevier

    Professor Enrico M. Clini

  25. Role of COVID‐19 in the Progression of Scleroderma Interstitial Lung Disease and New Onset Pulmonary Hypertension: A Challenging Case Report

    Article • Respirology Case Reports, May 2025, Wiley

    Professor Enrico M. Clini

  26. The Link Between Sleep-Related Breathing Disorders and Idiopathic Pulmonary Fibrosis: Pathophysiological Mechanisms and Treatment Options—A Review

    Article • Journal of Clinical Medicine, March 2025, MDPI AG

    Professor Enrico M. Clini

  27. Machine learning models compared with current clinical indices to predict the outcome of high flow nasal cannula therapy in acute hypoxemic respiratory failure

    Article • Critical Care, March 2025, Springer Science + Business Media

    Professor Enrico M. Clini

  28. Respiratory Muscle Dysfunction and Associated Risk Factors Following COVID-19-Related Hospitalisation

    Article • Life, January 2025, MDPI AG

    Professor Enrico M. Clini

  29. Airway pressures generated by high flow nasal cannula in patients with acute hypoxemic respiratory failure: a computational study

    Article • Respiratory Research, January 2025, Springer Science + Business Media

    Professor Enrico M. Clini

  30. Genetic Risk Factors in Idiopathic and Non-Idiopathic Interstitial Lung Disease: Similarities and Differences

    Article • Medicina, November 2024, MDPI AG

    Professor Enrico M. Clini

  31. Rehabilitation and physiotherapists in the critical care medicine

    Article • Pulmonology, October 2024, Taylor & Francis

    Professor Enrico M. Clini

  32. Development of clinical tools to estimate the breathing effort during high-flow oxygen therapy: A multicenter cohort study

    Article • Pulmonology, October 2024, Taylor & Francis

    Professor Enrico M. Clini

  33. Quantitative CT-analysis of over aerated lung tissue and correlation with fibrosis extent in patients with idiopathic pulmonary fibrosis

    Article • Respiratory Research, October 2024, Springer Science + Business Media

    Professor Enrico M. Clini

  34. Bronchiectasis as long-term complication of acute fire smoke inhalation?

    Article • Pulmonology, September 2024, Taylor & Francis

    Professor Enrico M. Clini

  35. Monitoring and modulation of respiratory drive in patients with acute hypoxemic respiratory failure in spontaneous breathing

    Article • Internal and Emergency Medicine, August 2024, Springer Science + Business Media

    Professor Enrico M. Clini

  36. Influence of frailty on cardiovascular events and mortality in patients with Chronic Obstructive Pulmonary Disease (COPD): Study protocol for a multicentre European observational study

    Article • PLOS One, June 2024, PLOS

    Professor Enrico M. Clini

  37. Expression of HOXB7 in the Lung of Patients with Idiopathic Pulmonary Fibrosis: A Proof-of-Concept Study

    Article • Biomedicines, June 2024, MDPI AG

    Professor Enrico M. Clini

  38. Stress–strain curve and elastic behavior of the fibrotic lung with usual interstitial pneumonia pattern during protective mechanical ventilation

    Article • Scientific Reports, June 2024, Springer Science + Business Media

    Professor Enrico M. Clini

  39. Digital Twins of Acute Hypoxemic Respiratory Failure Patients Suggest a Mechanistic Basis for Success and Failure of Noninvasive Ventilation

    Article • Critical Care Medicine, May 2024, Wolters Kluwer Health

    Professor Enrico M. Clini

  40. Association between respiratory distress time and invasive mechanical ventilation in COVID-19 patients: A multicentre regional cohort study

    Article • Pulmonology, May 2024, Taylor & Francis

    MD Massimo Girardis, Professor Enrico M. Clini

  41. Integrated endoscopic treatment of primitive unresectable tracheal tumor: the INTACT retrospective cohort study

    Article • Journal of Thoracic Disease, May 2024, AME Publishing Company

    Professor Enrico M. Clini

  42. When sarcoidosis hits down: a case of prostatic sarcoidosis

    Article • Multidisciplinary Respiratory Medicine, April 2024, Mattioli1885

    Professor Enrico M. Clini

  43. Influence of frailty on cardiovascular events and mortality in patients with Chronic Obstructive Pulmonary Disease (COPD): Study Protocol for a multicentre European observational study

    Article • March 2024, Cold Spring Harbor Laboratory Press

    Professor Enrico M. Clini

  44. Editorial: Pulmonary fibrosis and lung carcinogenesis: do myofibroblasts and cancer-associated fibroblasts share a common identity?

    Article • Frontiers in Oncology, March 2024, Frontiers

    Daniela de Totero, Professor Enrico M. Clini

  45. Impact of Frailty on Symptom Burden in Chronic Obstructive Pulmonary Disease

    Article • Journal of Clinical Medicine, February 2024, MDPI AG

    Professor Enrico M. Clini

  46. Proteomic profiling of formalin-fixed paraffine-embedded tissue reveals key proteins related to lung dysfunction in idiopathic pulmonary fibrosis

    Article • Frontiers in Oncology, January 2024, Frontiers

    Professor Enrico M. Clini

  47. Efficacy of Respiratory Muscle Training in the Immediate Postoperative Period of Cardiac Surgery: A Systematic Review and Meta-Analysis

    Article • Brazilian Journal of Cardiovascular Surgery, January 2024, Sociedade Brasileira de Cirurgia Cardiovascular

    Professor Enrico M. Clini

  48. Home noninvasive ventilation in severe COPD: in whom does it work and how?

    Article • ERJ Open Research, January 2024, European Respiratory Society (ERS)

    Professor Enrico M. Clini

  49. Effect of high flow nasal oxygen on inspiratory effort of patients with acute hypoxic respiratory failure and do not intubate orders

    Article • Internal and Emergency Medicine, December 2023, Springer Science + Business Media

    Professor Enrico M. Clini

  50. COVID-19, A New Possible Mimicker of Interstitial Lung Disease Related to Primary Sjögren’s Syndrome

    Article • Case Reports in Medicine, December 2023, Wiley

    Professor Enrico M. Clini

  51. Disease burden of people with uncontrolled severe asthma with and without biomarkers of inflammation

    Article • The Journal of Allergy and Clinical Immunology In Practice, December 2023, Elsevier

    Dr. Bo Ding, Dr Dimitar Sajkov, Professor Enrico M. Clini

  52. Inspiratory Effort and Respiratory Mechanics in Patients with Acute Exacerbation of Idiopathic Pulmonary fibrosis: A Preliminary Matched Control Study

    Article • Pulmonology, November 2023, Taylor & Francis

    Professor Enrico M. Clini

  53. Stress-strain curve and elastic behavior of the fibrotic lung with usual interstitial pneumonia pattern during protective mechanical ventilation

    Article • November 2023, Research Square

    Professor Enrico M. Clini

  54. Association between Pulmonary Aspergillosis and Cytomegalovirus Reactivation in Critically Ill COVID-19 Patients: A Prospective Observational Cohort Study

    Article • Viruses, November 2023, MDPI AG

    Professor Enrico M. Clini

  55. Physiological effects of lung-protective ventilation in patients with lung fibrosis and usual interstitial pneumonia pattern versus primary ARDS: a matched-control study

    Article • Critical Care, October 2023, Springer Science + Business Media

    Professor Enrico M. Clini

  56. The Association of Procalcitonin and C-Reactive Protein with Bacterial Infections Acquired during Intensive Care Unit Stay in COVID-19 Critically Ill Patients

    Article • Antibiotics, October 2023, MDPI AG

    MD Massimo Girardis, Professor Enrico M. Clini

  57. Low-molecular-weight heparin for the prevention of clinical worsening in severe non-critically ill COVID-19 patients: a joint analysis of two randomized controlled trials

    Article • Internal and Emergency Medicine, October 2023, Springer Science + Business Media

    Professor Enrico M. Clini

  58. Frailty and its influence on mortality and morbidity in COPD: A Systematic Review and Meta-Analysis

    Article • Internal and Emergency Medicine, September 2023, Springer Science + Business Media

    Professor Enrico M. Clini

  59. Cluster Analyses From the Real-World NOVELTY Study: Six Clusters Across the Asthma-COPD Spectrum

    Article • The Journal of Allergy and Clinical Immunology In Practice, September 2023, Elsevier

    Dr Dimitar Sajkov, Professor Enrico M. Clini

  60. Frailty Prevalence and Association with Clinical Outcomes in Interstitial Lung Disease, Asthma, and Pleural Disease

    Article • Geriatrics, August 2023, MDPI AG

    Professor Enrico M. Clini

  61. Molecular Biology and Therapeutic Targets of Primitive Tracheal Tumors: Focus on Tumors Derived by Salivary Glands and Squamous Cell Carcinoma

    Article • International Journal of Molecular Sciences, July 2023, MDPI AG

    Professor Enrico M. Clini

  62. Quality of life and intrinsic capacity in patients with post-acute COVID-19 syndrome is in relation to frailty and resilience phenotypes

    Article • Scientific Reports, June 2023, Springer Science + Business Media

    Professor Enrico M. Clini

  63. Critical COVID-19 patients through first, second, and third wave: retrospective observational study comparing outcomes in intensive care unit

    Article • Journal of Thoracic Disease, June 2023, AME Publishing Company

    Professor Enrico M. Clini

  64. Prevalence of asthma and COPD in a cohort of patients at the follow up after COVID-19 pneumonia

    Article • Pulmonology, May 2023, Taylor & Francis

    Professor Enrico M. Clini

  65. One‐year clinical experience on the use of Nintedanib in systemic sclerosis

    Article • Respirology Case Reports, May 2023, Wiley

    Professor Enrico M. Clini

  66. Case report: Endoscopic closure with double stenting and autologous fascia lata graft of large tracheo-esophageal fistula

    Article • Frontiers in Surgery, April 2023, Frontiers

    Professor Enrico M. Clini

  67. Chronic Airways Assessment Test: psychometric properties in patients with asthma and/or COPD

    Article • April 2023, Springer Science + Business Media

    Dr Dimitar Sajkov, Professor Enrico M. Clini

  68. Accuracy of Nasal Pressure Swing to Predict Failure of High-Flow Nasal Oxygen in Patients with Acute Hypoxemic Respiratory Failure

    Article • American Review of Respiratory Disease, March 2023, American Thoracic Society

    Professor Enrico M. Clini

  69. Role of Selective Digestive Decontamination in the Prevention of Ventilator-Associated Pneumonia in COVID-19 Patients: A Pre-Post Observational Study

    Article • Journal of Clinical Medicine, February 2023, MDPI AG

    MD Massimo Girardis, Professor Enrico M. Clini

  70. COPD: Providing the right treatment for the right patient at the right time

    Article • Respiratory Medicine, February 2023, Elsevier

    Professor Enrico M. Clini

  71. Do All Critically Ill Patients with COVID-19 Disease Benefit from Adding Tocilizumab to Glucocorticoids? A Retrospective Cohort Study

    Article • Viruses, January 2023, MDPI AG

    MD Massimo Girardis, Professor Enrico M. Clini

  72. Endoscopic Bronchopleural Fistula Repair Using Autologous Fat Graft

    Article • The Annals of Thoracic Surgery, November 2022, Elsevier

    Professor Enrico M. Clini

  73. Biological effects of COVID-19 on lung cancer: Can we drive our decisions

    Article • Frontiers in Oncology, October 2022, Frontiers

    Professor Enrico M. Clini

  74. Delirium incidence and risk factors in patients undergoing non-invasive ventilation for acute respiratory failure: a multicenter observational trial

    Article • Minerva Anestesiologica, October 2022, Edizioni Minerva Medica

    Professor Enrico M. Clini

  75. Comparison between first and second wave of COVID-19 outbreak in older people: the COPE multicentre European observational cohort study

    Article • European Journal of Public Health, August 2022, Oxford University Press (OUP)

    Professor Enrico M. Clini

  76. The burden of disease in people with mild asthma

    Article • Respiratory Medicine, August 2022, Elsevier

    Sarowar Golam, Dr Dimitar Sajkov, Professor Enrico M. Clini

  77. Treatable traits in the NOVELTY study

    Article • Respirology, July 2022, Wiley

    Alvar Agustí, Dr Dimitar Sajkov, Professor Enrico M. Clini

  78. The role of immune response in the pathogenesis of idiopathic pulmonary fibrosis: far beyond the Th1/Th2 imbalance

    Article • Expert Opinion on Therapeutic Targets, July 2022, Taylor & Francis

    Professor Enrico M. Clini

  79. Cytomegalovirus blood reactivation in COVID-19 critically ill patients: risk factors and impact on mortality

    Article • Intensive Care Medicine, May 2022, Springer Science + Business Media

    MD Massimo Girardis, Professor Enrico M. Clini

  80. High-flow nasal oxygen versus conventional oxygen therapy in patients with COVID-19 pneumonia and mild hypoxaemia: a randomised controlled trial

    Article • Thorax, May 2022, BMJ

    Professor Enrico M. Clini

  81. Persistent asthma hospitalisations and deaths require a national asthma prevention plan

    Article • Internal and Emergency Medicine, May 2022, Springer Science + Business Media

    Professor Enrico M. Clini

  82. Early awake proning in critical and severe COVID-19 patients undergoing noninvasive respiratory support: A retrospective multicenter cohort study

    Article • Pulmonology, May 2022, Taylor & Francis

    MD Massimo Girardis, Professor Enrico M. Clini

  83. Risk Factors for Pulmonary Air Leak and Clinical Prognosis in Patients With COVID-19 Related Acute Respiratory Failure: A Retrospective Matched Control Study

    Article • Frontiers in Medicine, March 2022, Frontiers

    MD Massimo Girardis, Professor Enrico M. Clini

  84. Nasal pressure swings as the measure of inspiratory effort in spontaneously breathing patients with de novo acute respiratory failure

    Article • Critical Care, March 2022, Springer Science + Business Media

    MD Massimo Girardis, Professor Enrico M. Clini

  85. Different Methods to Improve the Monitoring of Noninvasive Respiratory Support of Patients with Severe Pneumonia/ARDS Due to COVID-19: An Update

    Article • Journal of Clinical Medicine, March 2022, MDPI AG

    Professor Enrico M. Clini

  86. Rehabilitation of Difficult-to-Wean, Tracheostomized Patients Admitted to Specialized Unit: Retrospective Analyses over 10-Years

    Article • International Journal of Environmental Research and Public Health, March 2022, MDPI AG

    Professor Enrico M. Clini, stefania costi

  87. Stenting versus balloon dilatation in patients with tracheal benign stenosis: The STROBE trial

    Article • Laryngoscope Investigative Otolaryngology, February 2022, Wiley

    Professor Enrico M. Clini

  88. Molecular Mechanisms and Physiological Changes behind Benign Tracheal and Subglottic Stenosis in Adults

    Article • International Journal of Molecular Sciences, February 2022, MDPI AG

    Professor Enrico M. Clini

  89. Prognostic value of estimated glomerular filtration rate in hospitalised older patients (over 65) with COVID-19: a multicentre, European, observational cohort study

    Article • BMC Geriatrics, February 2022, Springer Science + Business Media

    Professor Enrico M. Clini

  90. Correction: Endobronchial valve positioning for alveolar-pleural fistula following ICU management complicating COVID-19 pneumonia

    Article • BMC Pulmonary Medicine, February 2022, Springer Science + Business Media

    MD Massimo Girardis, Professor Enrico M. Clini

  91. Metabolic-Associated Fatty Liver Disease Is Highly Prevalent in the Postacute COVID Syndrome

    Article • Open Forum Infectious Diseases, January 2022, Oxford University Press (OUP)

    Professor Enrico M. Clini

  92. First and second waves among hospitalised patients with COVID-19 with severe pneumonia: a comparison of 28-day mortality over the 1-year pandemic in a tertiary university hospital in Italy

    Article • BMJ Open, January 2022, BMJ

    MD Massimo Girardis, Professor Enrico M. Clini

  93. Extensive Tracheal Injuries: A Reasoned Multistep Approach to Guarantee Mechanical Ventilatory Support Developed During the COVID‐19 Pandemic

    Article • OTO Open, January 2022, Wiley

    Professor Enrico M. Clini

  94. Development of post-COVID-19 cardiovascular events: an analysis of clinical features and risk factors from a single hospital retrospective study

    Article • Infezioni in Medicina, December 2021, Edizioni Internazionali srl, Divisione EDIMES Edizioni Medico-Scientifiche

    MD Massimo Girardis, Professor Enrico M. Clini

  95. In memoriam Claudio F. Donner

    Article • Pulmonology, November 2021, Taylor & Francis

    Professor Enrico M. Clini

  96. Rituximab for the treatment of acute onset Interstitial Lung Disease in primary Sjogren's syndrome

    Article • Pulmonology, November 2021, Taylor & Francis

    Professor Enrico M. Clini

  97. Urgent need of novel biomarkers of acute dyspnea

    Article • Internal and Emergency Medicine, November 2021, Springer Science + Business Media

    Professor Enrico M. Clini

  98. Molecular Mechanisms and Cellular Contribution from Lung Fibrosis to Lung Cancer Development

    Article • International Journal of Molecular Sciences, November 2021, MDPI AG

    Professor Enrico M. Clini

  99. Acute severe asthma: management and treatment

    Article • Minerva Medica, November 2021, Edizioni Minerva Medica

    Professor Enrico M. Clini

  100. Combined approach to define the clinical impact and decision making in asthmatics

    Article • Minerva Medica, November 2021, Edizioni Minerva Medica

    Professor Enrico M. Clini

  101. Correction to: Tocilizumab for patients with COVID-19 pneumonia. The single-arm TOCIVID-19 prospective trial

    Article • Journal of Translational Medicine, October 2021, Springer Science + Business Media

    MD Massimo Girardis, Professor Enrico M. Clini, Dr marco cascella

  102. Endobronchial valve positioning for alveolar-pleural fistula following ICU management complicating COVID-19 pneumonia

    Article • BMC Pulmonary Medicine, September 2021, Springer Science + Business Media

    MD Massimo Girardis, Professor Enrico M. Clini

  103. ERS/EAACI statement on adherence to international adult asthma guidelines

    Article • European Respiratory Review, September 2021, European Respiratory Society (ERS)

    Dr Alexander G Mathioudakis, Professor Enrico M. Clini, Alexander Mathioudakis

  104. Inspiratory Effort and Lung Mechanics in Spontaneously Breathing Patients with Acute Respiratory Failure due to COVID-19: A Matched Control Study

    Article • American Review of Respiratory Disease, September 2021, American Thoracic Society

    MD Massimo Girardis, Professor Enrico M. Clini

  105. Herpes Simplex Virus Re-Activation in Patients with SARS-CoV-2 Pneumonia: A Prospective, Observational Study

    Article • Microorganisms, September 2021, MDPI AG

    MD Massimo Girardis, Professor Enrico M. Clini

  106. Differences between Acute Exacerbations of Idiopathic Pulmonary Fibrosis and Other Interstitial Lung Diseases

    Article • Diagnostics, September 2021, MDPI AG

    Professor Enrico M. Clini

  107. Changes in Clinical Characteristics and Outcomes of Patients Admitted to Inpatient Cardiac Rehabilitation

    Article • International Journal of Environmental Research and Public Health, August 2021, MDPI AG

    Professor Enrico M. Clini, stefania costi

  108. Fibrotic Idiopathic Interstitial Lung Disease: The Molecular and Cellular Key Players

    Article • International Journal of Molecular Sciences, August 2021, MDPI AG

    Professor Enrico M. Clini

  109. Better prognosis in females with severe COVID-19 pneumonia: possible role of inflammation as potential mediator

    Article • Clinical Microbiology and Infection, August 2021, Elsevier

    MD Massimo Girardis, Professor Enrico M. Clini

  110. Rehabilitative practice in Europe: Roles and competencies of physiotherapists. Are we learning something new from COVID-19 pandemic?

    Article • Pulmonology, July 2021, Taylor & Francis

    Professor Enrico M. Clini, stefania costi

  111. Dissecting the Role of Mesenchymal Stem Cells in Idiopathic Pulmonary Fibrosis: Cause or Solution

    Article • Frontiers in Pharmacology, July 2021, Frontiers

    Professor Enrico M. Clini

  112. Pulmonary Stretch and Lung Mechanotransduction: Implications for Progression in the Fibrotic Lung

    Article • International Journal of Molecular Sciences, June 2021, MDPI AG

    Professor Enrico M. Clini

  113. Interstitial Lung Disease and Anti-Myeloperoxidase Antibodies: Not a Simple Association

    Article • Journal of Clinical Medicine, June 2021, MDPI AG

    Professor Enrico M. Clini

  114. Effects of cytokine blocking agents on hospital mortality in patients admitted to ICU with acute respiratory distress syndrome by SARS-CoV-2 infection: retrospective cohort study

    Article • Multidisciplinary Respiratory Medicine, May 2021, PAGEPress Publications

    Prof. João Leitão, Professor Enrico M. Clini

  115. Never Give Up: Lesson learned from a severe COVID-19 patient

    Article • Pulmonology, May 2021, Taylor & Francis

    MD Massimo Girardis, Professor Enrico M. Clini

  116. Defining Modern Pulmonary Rehabilitation. An Official American Thoracic Society Workshop Report

    Article • Annals of the American Thoracic Society, May 2021, American Thoracic Society

    Professor Enrico M. Clini

  117. COVID-Guide: una app per il triage e l’autovalutazione della covid-19

    Article • Recenti Progressi in Medicina, May 2021, Il Pensiero Scientifico Editore

    Professor Enrico M. Clini

  118. Comments on “Preventive home therapy for symptomatic patients affected by COVID-19 and followed by teleconsultations” by D’Amato et al.

    Article • Multidisciplinary Respiratory Medicine, April 2021, Mattioli1885

    Professor Enrico M. Clini

  119. Spontaneous Breathing and Evolving Phenotypes of Lung Damage in Patients with COVID-19: Review of Current Evidence and Forecast of a New Scenario

    Article • Journal of Clinical Medicine, March 2021, MDPI AG

    Professor Enrico M. Clini

  120. Development and validation of a prediction model for tocilizumab failure in hospitalized patients with SARS-CoV-2 infection

    Article • PLOS One, February 2021, PLOS

    MD Massimo Girardis, Professor Enrico M. Clini

  121. Looking Ahead in Pulmonary Rehabilitation

    Article • Frontiers in Rehabilitation Sciences, February 2021, Frontiers

    Professor Enrico M. Clini

  122. Routine use of immunosuppressants is associated with mortality in hospitalised patients with COVID-19

    Article • Therapeutic Advances in Drug Safety, January 2021, SAGE Publications

    Professor Enrico M. Clini

  123. Reply to Spinelli et al. and to Jha: Continued Vigorous Inspiratory Effort as a Predictor of Noninvasive Ventilation Failure

    Article • American Review of Respiratory Disease, December 2020, American Thoracic Society

    Professor Enrico M. Clini

  124. High flow nasal therapy versus noninvasive ventilation as initial ventilatory strategy in COPD exacerbation: a multicenter non-inferiority randomized trial

    Article • Critical Care, December 2020, Springer Science + Business Media

    Professor Enrico M. Clini

  125. Increased care at discharge from COVID-19: The association between pre-admission frailty and increased care needs after hospital discharge; a multicentre European observational cohort study

    Article • BMC Medicine, December 2020, Springer Science + Business Media

    Professor Enrico M. Clini

  126. The influence of ACE inhibitors and ARBs on hospital length of stay and survival in people with COVID-19

    Article • IJC Heart & Vasculature, December 2020, Elsevier

    Professor Enrico M. Clini

  127. Unusual effectiveness of systemic steroids in Whipple disease

    Article • Pulmonology, November 2020, Taylor & Francis

    Professor Enrico M. Clini

  128. Machine learning in predicting respiratory failure in patients with COVID-19 pneumonia—Challenges, strengths, and opportunities in a global health emergency

    Article • PLOS One, November 2020, PLOS

    MD Massimo Girardis, Professor Enrico M. Clini

  129. Echoendoscopic appearance of mediastinal metastasis from papillary renal carcinoma

    Article • Thoracic Cancer, October 2020, Wiley

    Professor Enrico M. Clini

  130. Integrated intErventional bronchoscopy in the treatment of locally adVanced non-small lung cancER with central Malignant airway Obstructions: a multicentric REtrospective study (EVERMORE)

    Article • Lung Cancer, October 2020, Elsevier

    Professor Enrico M. Clini

  131. Nosocomial COVID-19 infection: examining the risk of mortality. The COPE-Nosocomial Study (COVID in Older PEople)

    Article • Journal of Hospital Infection, October 2020, Elsevier

    Professor Enrico M. Clini

  132. Reply to Tuffet et al. and to Michard and Shelley

    Article • American Review of Respiratory Disease, September 2020, American Thoracic Society

    Professor Enrico M. Clini

  133. Two Fatal Cases of Acute Liver Failure Due to HSV-1 Infection in COVID-19 Patients Following Immunomodulatory Therapies

    Article • Clinical Infectious Diseases, August 2020, Oxford University Press (OUP)

    MD Massimo Girardis, Professor Enrico M. Clini

  134. Early Inspiratory Effort Assessment by Esophageal Manometry Predicts Noninvasive Ventilation Outcome in De Novo Respiratory Failure. A Pilot Study

    Article • American Review of Respiratory Disease, August 2020, American Thoracic Society

    MD Massimo Girardis, Professor Enrico M. Clini

  135. Feasibility and clinical impact of out-of-ICU noninvasive respiratory support in patients with COVID-19-related pneumonia

    Article • European Respiratory Journal, August 2020, European Respiratory Society (ERS)

    Professor Enrico M. Clini

  136. Tocilizumab in patients with severe COVID-19: a retrospective cohort study

    Article • The Lancet Rheumatology, August 2020, Elsevier

    MD Massimo Girardis, Professor Enrico M. Clini

  137. The effect of frailty on survival in patients with COVID-19 (COPE): a multicentre, European, observational cohort study

    Article • The Lancet Public Health, August 2020, Elsevier

    Professor Enrico M. Clini

  138. Pneumonic versus Nonpneumonic Exacerbations of Chronic Obstructive Pulmonary Disease

    Article • Seminars in Respiratory and Critical Care Medicine, July 2020, Thieme Publishing Group

    Professor Enrico M. Clini

  139. Marked T cell activation, senescence, exhaustion and skewing towards TH17 in patients with COVID-19 pneumonia

    Article • Nature Communications, July 2020, Springer Science + Business Media

    MD Massimo Girardis, Professor Enrico M. Clini

  140. Randomised controlled trial comparing efficacy and safety of high versus low Low-Molecular Weight Heparin dosages in hospitalized patients with severe COVID-19 pneumonia and coagulopathy not requiring invasive mechanical ventilation (COVID-19 HD): a st...

    Article • Trials, June 2020, Springer Science + Business Media

    Professor Enrico M. Clini

  141. Italian suggestions for pulmonary rehabilitation in COVID-19 patients recovering from acute respiratory failure: results of a Delphi process

    Article • Monaldi Archives for Chest Disease, June 2020, PAGEPress Publications

    Professor Enrico M. Clini

  142. COVID-19 and pulmonary rehabilitation: preparing for phase three

    Article • European Respiratory Journal, June 2020, European Respiratory Society (ERS)

    Professor Enrico M. Clini

  143. Subclinical liver fibrosis in patients with idiopathic pulmonary fibrosis

    Article • Internal and Emergency Medicine, May 2020, Springer Science + Business Media

    Professor Enrico M. Clini

  144. An Italian sacrifice to the COVID-19 epidemic

    Article • European Respiratory Journal, May 2020, European Respiratory Society (ERS)

    Professor Enrico M. Clini

  145. High-Flow Oxygen Therapy During Exercise Training in Patients With Chronic Obstructive Pulmonary Disease and Chronic Hypoxemia: A Multicenter Randomized Controlled Trial

    Article • Physical Therapy, April 2020, Oxford University Press (OUP)

    Professor Enrico M. Clini

  146. Handling and Processing of Blood Specimens from Patients with COVID‐19 for Safe Studies on Cell Phenotype and Cytokine Storm

    Article • Cytometry Part A, April 2020, Wiley

    MD Massimo Girardis, Professor Enrico M. Clini

  147. Obstructive sleep apnea and blood pressure in young hypertensives: does it matter?

    Article • Internal and Emergency Medicine, March 2020, Springer Science + Business Media

    Professor Enrico M. Clini

  148. Ventilatory support and mechanical properties of the fibrotic lung acting as a “squishy ball”

    Article • Annals of Intensive Care, February 2020, Springer Science + Business Media

    Professor Enrico M. Clini

  149. Surfactant replacement might help recovery of low-compliance lung in severe COVID-19 pneumonia

    Article • Therapeutic Advances in Respiratory Disease, January 2020, SAGE Publications

    MD Massimo Girardis, Professor Enrico M. Clini

  150. Joint Statement on the Role of Respiratory Rehabilitation in the COVID-19 Crisis: The Italian Position Paper

    Article • Respiration, January 2020, Karger Publishers

    Professor Enrico M. Clini

  151. Baseline Exercise Tolerance and Perceived Dyspnea to Identify the Ideal Candidate to Pulmonary Rehabilitation: A Risk Chart in COPD Patients

    Article • International Journal of Chronic Obstructive Pulmonary Disease, December 2019, Taylor & Francis

    stefania costi, Professor Enrico M. Clini, Silvia Faverzani

  152. Vessel Diseases

    Article • European Heart Journal Supplements, December 2019, Oxford University Press (OUP)

    Professor Enrico M. Clini

  153. A case of dyspnea: respiratory failure due to pulmonary arteriovenous malformation

    Article • Italian Journal of Medicine, November 2019, PAGEPress Publications

    Professor Enrico M. Clini

  154. Prognostication by concomitant organ failure in mechanically ventilated patients in ICU: Important issue to face with

    Article • European Journal of Internal Medicine, November 2019, Elsevier

    Professor Enrico M. Clini

  155. Real-life comparison of pirfenidone and nintedanib in patients with idiopathic pulmonary fibrosis: A 24-month assessment

    Article • Respiratory Medicine, November 2019, Elsevier

    Professor Enrico M. Clini

  156. Respiratory Mechanics and Diaphragmatic Dysfunction in COPD Patients Who Failed Non-Invasive Mechanical Ventilation

    Article • International Journal of Chronic Obstructive Pulmonary Disease, November 2019, Taylor & Francis

    Professor Enrico M. Clini, roberto tonelli

  157. Prevalence and development of chronic critical illness in acute patients admitted to a respiratory intensive care setting

    Article • Pulmonology, October 2019, Elsevier

    Professor Enrico M. Clini

  158. Gender differences in chronic obstructive pulmonary disease: Can be the DRG-based diagnosis the best way for a right analysis?

    Article • Italian Journal of Medicine, September 2019, PAGEPress Publications

    Professor Enrico M. Clini, Giancarlo Garuti

  159. Atypical diagnosis for typical lung carcinoid

    Article • BMC Pulmonary Medicine, September 2019, Springer Science + Business Media

    Professor Enrico M. Clini

  160. European Respiratory Society guidelines on long-term home non-invasive ventilation for management of COPD

    Article • European Respiratory Journal, August 2019, European Respiratory Society (ERS)

    Professor Enrico M. Clini, Prof Nicholas Hart

  161. Serial ultrasound assessment of diaphragmatic function and clinical outcome in patients with amyotrophic lateral sclerosis

    Article • BMC Pulmonary Medicine, August 2019, Springer Science + Business Media

    Professor Enrico M. Clini

  162. Arachidonic Acid and Docosahexaenoic Acid Metabolites in the Airways of Adults With Cystic Fibrosis: Effect of Docosahexaenoic Acid Supplementation

    Article • Frontiers in Pharmacology, August 2019, Frontiers

    Professor Enrico M. Clini

  163. Janus-faced amiodarone-induced pneumopathy

    Article • Pulmonology, August 2019, Elsevier

    Professor Enrico M. Clini

  164. Clinical differences in sarcoidosis patients with and without lymphoma

    Article • European Respiratory Journal, July 2019, European Respiratory Society (ERS)

    Professor Enrico M. Clini, Prof. Fabrizio Luppi

  165. Do Not Forget to Assess the Muscle Integrity in Patients With COPD

    Article • CHEST Journal, June 2019, Elsevier

    Professor Enrico M. Clini

  166. Introduction of the harmonised respiratory physiotherapy curriculum

    Article • Breathe, June 2019, European Respiratory Society (ERS)

    Professor Enrico M. Clini, Dr Agnieszka Lewko

  167. A guide for respiratory physiotherapy postgraduate education: presentation of the harmonised curriculum

    Article • European Respiratory Journal, June 2019, European Respiratory Society (ERS)

    Thierry Troosters, Professor Enrico M. Clini, Dr Agnieszka Lewko

  168. Manual Massage Therapy for Patients with COPD: A Scoping Review

    Article • Medicina, May 2019, MDPI AG

    Professor Enrico M. Clini

  169. Exercise and Sports Pulmonology

    Article • January 2019, Springer Science + Business Media

    Professor Enrico M. Clini

  170. Cardiac disease

    Article • January 2019, European Respiratory Society (ERS)

    Professor Enrico M. Clini

  171. Pulmonary Rehabilitation

    Article • January 2019, Springer Science + Business Media

    Professor Enrico M. Clini

  172. Assessment of Symptoms in Patients with COPD: Strengths and Limitations of Clinical Scores

    Article • Current Pulmonology Reports, October 2018, Springer Science + Business Media

    Professor Enrico M. Clini

  173. LABA/LAMA fixed-dose combinations in patients with COPD: a systematic review

    Article • International Journal of Chronic Obstructive Pulmonary Disease, October 2018, Dove Medical Press

    Professor Enrico M. Clini, Professor Fulvio Braido, Mario Cazzola

  174. Breathlessness, but not cough, suggests chronic obstructive pulmonary disease in elderly smokers with stable heart failure

    Article • Multidisciplinary Respiratory Medicine, October 2018, Springer Science + Business Media

    Professor Enrico M. Clini

  175. Three-Year Hospitalization and Mortality in Elderly Smokers with Chronic Obstructive Pulmonary Disease or Chronic Heart Failure

    Article • Respiration, September 2018, Karger Publishers

    Professor Enrico M. Clini

  176. An uncommon cause of hemoptysis: aortobronchial fistula

    Article • Multidisciplinary Respiratory Medicine, September 2018, Springer Science + Business Media

    Professor Enrico M. Clini

  177. Tai Chi Recreational Exercise Is Not Rehabilitation

    Article • CHEST Journal, September 2018, Elsevier

    Professor Enrico M. Clini

  178. Evaluation of health-related quality of life in pulmonary diseases

    Article • International Journal of Therapy and Rehabilitation, August 2018, Mark Allen Group

    Professor Enrico M. Clini

  179. The encaged lung: rapidly progressive idiopathic pleurisy

    Article • Oxford Medical Case Reports, August 2018, Oxford University Press (OUP)

    Professor Enrico M. Clini

  180. Vanishing lung emphysema during chemotherapy for malignant pleural mesothelioma

    Article • Chest Disease Reports, July 2018, PAGEPress Publications

    Professor Enrico M. Clini

  181. Use of adjunct cardiovascular therapy in patients hospitalised for acute exacerbations of COPD

    Article • ERJ Open Research, July 2018, European Respiratory Society (ERS)

    Professor Enrico M. Clini

  182. Ultrasound-assessed diaphragmatic impairment is a predictor of outcomes in patients with acute exacerbation of chronic obstructive pulmonary disease undergoing noninvasive ventilation

    Article • Critical Care, April 2018, Springer Science + Business Media

    Professor Enrico M. Clini

  183. Pretreatment rate of decay in forced vital capacity predicts long-term response to pirfenidone in patients with idiopathic pulmonary fibrosis

    Article • Scientific Reports, April 2018, Springer Science + Business Media

    Professor Enrico M. Clini

  184. Acute exacerbation of idiopathic pulmonary fibrosis: lessons learned from acute respiratory distress syndrome?

    Article • Critical Care, March 2018, Springer Science + Business Media

    Professor Enrico M. Clini

  185. Update in rehabilitation of respiratory patients

    Article • January 2018, Springer Science + Business Media

    Professor Enrico M. Clini

  186. Looking for a chronic care model in COPD patients

    Article • European Respiratory Journal, January 2018, European Respiratory Society (ERS)

    Professor Enrico M. Clini

  187. Pulmonary rehabilitation for patients with COPD during and after an exacerbation-related hospitalisation: back to the future?

    Article • European Respiratory Journal, January 2018, European Respiratory Society (ERS)

    Professor Enrico M. Clini

  188. Incidence, Etiology, and Clinicopathologic Features of Endobronchial Benign Lesions

    Article • Journal of Bronchology & Interventional Pulmonology, January 2018, Wolters Kluwer Health

    Professor Enrico M. Clini

  189. Conventional Programs: Settings, Cost, Staffing, and Maintenance

    Article • December 2017, Springer Science + Business Media

    Professor Enrico M. Clini

  190. Conclusions: Perspectives in Pulmonary Rehabilitation

    Article • December 2017, Springer Science + Business Media

    Professor Enrico M. Clini

  191. Effectiveness of pulmonary rehabilitation in patients with interstitial lung disease of different etiology: a multicenter prospective study

    Article • BMC Pulmonary Medicine, October 2017, Springer Science + Business Media

    Professor Enrico M. Clini

  192. Chronic Respiratory Abnormalities in the Multi-Morbid Frail Elderly

    Article • Barcelona Respiratory Network, October 2017, Fundacao Barcelona Respiratory Network

    Professor Enrico M. Clini

  193. Update on physiotherapy applicable to patients in intensive care. Practical aspects and perspectives

    Article • August 2017, Springer Science + Business Media

    Professor Enrico M. Clini

  194. Endothelial dysfunction assessment by noninvasive peripheral arterial tonometry in patients with chronic obstructive pulmonary disease compared with healthy subjects

    Article • The Clinical Respiratory Journal, August 2017, Wiley

    Professor Enrico M. Clini

  195. The potential role of endothelial dysfunction and platelet activation in the development of thrombotic risk in COPD patients

    Article • Expert Review of Hematology, July 2017, Taylor & Francis

    Dr Alessandro Radaeli, Professor Enrico M. Clini

  196. Integrating the care of the complex COPD patient

    Article • Monaldi Archives for Chest Disease, May 2017, PAGEPress Publications

    Professor Enrico M. Clini

  197. GOLD 2017 recommendations for COPD patients: toward a more personalized approach

    Article • COPD Research and Practice, May 2017, Springer Science + Business Media

    Professor Enrico M. Clini

  198. COPD exacerbation and diaphragmatic dysfunction: Conditions with mutual influence influencing outcomes? - Reply

    Article • Respirology, March 2017, Wiley

    Professor Enrico M. Clini

  199. An uncommon cause of pneumonia: The golden diagnosis

    Article • Respiratory Medicine Case Reports, January 2017, Elsevier

    Professor Enrico M. Clini

  200. Prevalence and outcomes of diaphragmatic dysfunction assessed by ultrasound technology during acute exacerbation of COPD: A pilot study

    Article • Respirology, October 2016, Wiley

    Professor Enrico M. Clini

  201. What is the origin of dyspnoea in smokers without airway disease?

    Article • European Respiratory Journal, August 2016, European Respiratory Society (ERS)

    Professor Enrico M. Clini

  202. Increasing implementation and delivery of pulmonary rehabilitation: key messages from the new ATS/ERS policy statement

    Article • European Respiratory Journal, April 2016, European Respiratory Society (ERS)

    Dr IOANNIS VOGIATZIS, Professor Enrico M. Clini

  203. Management and Therapy for Pulmonary Hypertension: 2016 Update

    Article • Barcelona Respiratory Network, April 2016, Fundacao Barcelona Respiratory Network

    Professor Enrico M. Clini

  204. Ultrasound assessment of diaphragmatic function in patients with amyotrophic lateral sclerosis

    Article • Respirology, March 2016, Wiley

    Professor Enrico M. Clini

  205. Platelet activation and cardiovascular comorbidities in patients with chronic obstructive pulmonary disease

    Article • Current Medical Research and Opinion, March 2016, Informa Healthcare

    Professor Enrico M. Clini

  206. Exhaled and non-exhaled non-invasive markers for assessment of respiratory inflammation in patients with stable COPD and healthy smokers

    Article • Journal of Breath Research, January 2016, Institute of Physics Publishing

    Professor Enrico M. Clini

  207. Activity and analysis of costs in a dedicated weaning centre

    Article • Monaldi Archives for Chest Disease, January 2016, PAGEPress Publications

    Professor Enrico M. Clini

  208. Learning impact of education during Pulmonary Rehabilitation program. An observational short-term cohort study

    Article • Monaldi Archives for Chest Disease, January 2016, PAGEPress Publications

    Professor Enrico M. Clini

  209. Organization of a Weaning Unit

    Article • January 2016, Springer Science + Business Media

    Professor Enrico M. Clini

  210. La ventilazione non invasiva in Medicina Interna

    Article • Italian Journal of Medicine, December 2015, PAGEPress Publications

    Professor Enrico M. Clini, MD Matteo Giorgi-Pierfranceschi

  211. Advanced COPD patients under Home Mechanical Ventilation and/or Long Term Oxygen Therapy: Italian Healthcare Costs

    Article • Monaldi Archives for Chest Disease, December 2015, PAGEPress Publications

    Professor Enrico M. Clini

  212. An Official American Thoracic Society/European Respiratory Society Policy Statement: Enhancing Implementation, Use, and Delivery of Pulmonary Rehabilitation

    Article • American Review of Respiratory Disease, December 2015, American Thoracic Society

    Professor Enrico M. Clini

  213. Response to pulmonary rehabilitation: toward personalised programmes?

    Article • European Respiratory Journal, November 2015, European Respiratory Society (ERS)

    Nicolino Ambrosino, Professor Enrico M. Clini

  214. Chronic critical illness: the price of survival

    Article • European Journal of Clinical Investigation, November 2015, Wiley

    Professor Enrico M. Clini

  215. 8th International conference on management and rehabilitation of chronic respiratory failure: the long summaries – Part 3

    Article • Multidisciplinary Respiratory Medicine, October 2015, Springer Science + Business Media

    Professor Enrico M. Clini

  216. 8th International conference on management and rehabilitation of chronic respiratory failure: the long summaries – part 2

    Article • Multidisciplinary Respiratory Medicine, October 2015, Springer Science + Business Media

    Professor Enrico M. Clini

  217. 8th international conference on management and rehabilitation of chronic respiratory failure: the long summaries – part 1

    Article • Multidisciplinary Respiratory Medicine, October 2015, Springer Science + Business Media

    Professor Enrico M. Clini

  218. Comorbidities in elderly smokers with COPD or CHF

    Article • September 2015, European Respiratory Society (ERS)

    Professor Enrico M. Clini

  219. Impaired function in the complex patient with COPD: a matter to be considered

    Article • Revista Portuguesa de Pneumologia (English Edition), September 2015, Elsevier

    Professor Enrico M. Clini

  220. An official American Thoracic Society/European Respiratory Society statement: research questions in COPD

    Article • European Respiratory Review, May 2015, European Respiratory Society (ERS)

    Professor Enrico M. Clini

  221. Clinical highlights: messages from Munich

    Article • ERJ Open Research, May 2015, European Respiratory Society (ERS)

    Professor Enrico M. Clini

  222. Development of a syllabus for postgraduate respiratory physiotherapy education: the Respiratory Physiotherapy HERMES project

    Article • European Respiratory Journal, April 2015, European Respiratory Society (ERS)

    Professor Enrico M. Clini, Dr Agnieszka Lewko

  223. An Official American Thoracic Society/European Respiratory Society Statement: Research Questions in Chronic Obstructive Pulmonary Disease

    Article • American Review of Respiratory Disease, April 2015, American Thoracic Society

    Professor Enrico M. Clini

  224. An official American Thoracic Society/European Respiratory Society statement: research questions in COPD

    Article • European Respiratory Journal, March 2015, European Respiratory Society (ERS)

    Professor Enrico M. Clini

  225. A Prospective Multicentric Study of Pulmonary Rehabilitation in Patients with Chronic Obstructive Pulmonary Disease and Different Clinical Phenotypes

    Article • Respiration, January 2015, Karger Publishers

    Professor Enrico M. Clini

  226. Symptomatic, frail, elderly patients: the urgent need for comprehensive assessment and management: Figure 1–

    Article • European Respiratory Journal, November 2014, European Respiratory Society (ERS)

    Professor Enrico M. Clini

  227. A conceptual framework for reporting experience of physical activity in COPD

    Article • European Respiratory Journal, October 2014, European Respiratory Society (ERS)

    Professor Enrico M. Clini

  228. Pulmonary rehabilitation in Italy: professional barriers to overcome

    Article • European Respiratory Journal, October 2014, European Respiratory Society (ERS)

    Professor Enrico M. Clini

  229. An official European Respiratory Society statement on physical activity in COPD

    Article • European Respiratory Journal, October 2014, European Respiratory Society (ERS)

    Professor Enrico M. Clini, Dr. Benjamin Waschki

  230. A core syllabus for post-graduate training in respiratory physiotherapy

    Article • Breathe, September 2014, European Respiratory Society (ERS)

    Professor Enrico M. Clini, Dr Agnieszka Lewko

  231. In COPD patients on prolonged mechanical ventilation heart rate variability during the T-piece trial is better after pressure support plus PEEP: A pilot physiological study

    Article • Heart & Lung, September 2014, Elsevier

    Professor Enrico M. Clini

  232. An early rehabilitation intervention to enhance recovery during hospital admission for an exacerbation of chronic respiratory disease: randomised controlled trial

    Article • BMJ, July 2014, BMJ

    Professor Enrico M. Clini

  233. Impaired arm activity in COPD: a questionable goal for rehabilitation

    Article • European Respiratory Journal, May 2014, European Respiratory Society (ERS)

    Professor Enrico M. Clini

  234. Clinical highlights from the 2013 ERS Congress in Barcelona

    Article • European Respiratory Journal, April 2014, European Respiratory Society (ERS)

    Professor Enrico M. Clini

  235. Rehabilitation and supportive therapy in elderly patients with Chronic Obstructive Pulmonary Disease

    Article • European Journal of Internal Medicine, April 2014, Elsevier

    MD Ernesto Crisafulli, Professor Enrico M. Clini

  236. Comorbidities in Chronic Obstructive Pulmonary Disease from Assessment to Treatment

    Article • BioMed Research International, January 2014, Hindawi Publishing Corporation

    Professor Enrico M. Clini

  237. Multimorbidity in Elderly Patients with Chronic Obstructive Pulmonary Disease: Stop Smoking! Go Exercise?

    Article • American Review of Respiratory Disease, January 2014, American Thoracic Society

    Professor Enrico M. Clini

  238. Differences in content and organisational aspects of pulmonary rehabilitation programmes

    Article • European Respiratory Journal, December 2013, European Respiratory Society (ERS)

    Dr Renae J McNamara, Professor Enrico M. Clini

  239. Fat-Free Mass Depletion Is Associated With Poor Exercise Capacity Irrespective of Dynamic Hyperinflation in COPD Patients

    Article • Respiratory Care, October 2013, Daedalus Enterprises

    Professor Enrico M. Clini

  240. An Official American Thoracic Society/European Respiratory Society Statement: Key Concepts and Advances in Pulmonary Rehabilitation

    Article • American Review of Respiratory Disease, October 2013, American Thoracic Society

    Professor Enrico M. Clini

  241. Chronic Obstructive Pulmonary Disease (COPD) and Metabolic Disorders in Elderly Smokers

    Article • CHEST Journal, October 2013, Elsevier

    Professor Enrico M. Clini

  242. Towards health benefits in chronic respiratory diseases: pulmonary rehabilitation

    Article • European Respiratory Review, August 2013, European Respiratory Society (ERS)

    Professor Enrico M. Clini

  243. Platelet activation as a novel mechanism of atherothrombotic risk in chronic obstructive pulmonary disease

    Article • Expert Review of Hematology, August 2013, Taylor & Francis

    Professor Enrico M. Clini

  244. Noninvasive mechanical ventilation with high pressure strategy remains a “double edged sword”?

    Article • International Journal of Chronic Obstructive Pulmonary Disease, May 2013, Taylor & Francis

    Professor Enrico M. Clini, Prof Nicholas Hart

  245. Systemic Inflammatory Pattern of Patients With Community-Acquired Pneumonia With and Without COPD

    Article • CHEST Journal, April 2013, Elsevier

    MD Ernesto Crisafulli, Professor Enrico M. Clini

  246. Diagnosis of Chronic Obstructive Pulmonary Disease, simpler is better Complexity and simplicity

    Article • European Journal of Internal Medicine, April 2013, Elsevier

    MD Ernesto Crisafulli, Professor Enrico M. Clini

  247. Chronic Obstructive Pulmonary Disease Is Just One Component of the Complex Multimorbidities in Patients with COPD

    Article • American Review of Respiratory Disease, April 2013, American Thoracic Society

    Professor Enrico M. Clini

  248. Mechanisms of acute exacerbation of respiratory symptoms in chronic obstructive pulmonary disease

    Article • European Journal of Clinical Investigation, March 2013, Wiley

    Professor Enrico M. Clini

  249. Predicting Walking-Induced Oxygen Desaturations in COPD Patients: A Statistical Model

    Article • Respiratory Care, January 2013, Daedalus Enterprises

    Professor Enrico M. Clini

  250. Feasibility and Effectiveness of an Educational Program in Italian COPD Patients Undergoing Rehabilitation

    Article • Respiratory Care, January 2013, Daedalus Enterprises

    Professor Enrico M. Clini

  251. Poor adherence to guidelines for long-term oxygen therapy (LTOT) in two Italian university hospitals

    Article • Internal and Emergency Medicine, January 2013, Springer Science + Business Media

    Prof Emidia Vagnoni, Professor Enrico M. Clini

  252. Effect of Rehabilitative Exercise Training on Peripheral Muscle Remodelling in Patients with COPD: Targeting Beyond the Lungs

    Article • Current Drug Targets, January 2013, Bentham Science Publishers

    Dr ELENI KORTIANOU, Professor Enrico M. Clini

  253. Pulmonary Rehabilitation Improves Cardiovascular Response to Exercise in COPD

    Article • Respiration, January 2013, Karger Publishers

    Professor Enrico M. Clini

  254. Respiratory Muscle Training in Patients Recovering Recent Open Cardiothoracic Surgery: A Randomized-Controlled Trial

    Article • BioMed Research International, January 2013, Hindawi Publishing Corporation

    Professor Enrico M. Clini

  255. Selected clinical highlights from the 2012 ERS congress in Vienna: Table 1–

    Article • European Respiratory Journal, December 2012, European Respiratory Society (ERS)

    Professor Enrico M. Clini

  256. Efficacy of temporary positive expiratory pressure (TPEP) in patients with lung diseases and chronic mucus hypersecretion. The UNIKO® project: a multicentre randomized controlled trial

    Article • Clinical Rehabilitation, September 2012, SAGE Publications

    Professor Enrico M. Clini

  257. Pulmonary rehabilitation following radical chemo-radiation in locally advanced non surgical NSCLC: Preliminary evidences

    Article • Lung Cancer, May 2012, Elsevier

    Professor Enrico M. Clini

  258. Clinical highlights from the 2011 ERS Congress in Amsterdam

    Article • European Respiratory Journal, March 2012, European Respiratory Society (ERS)

    Professor Enrico M. Clini

  259. Anthropometry in Special and Selective Conditions and Circumstances: Anthropometry as Measure of Risk in COPD Patients

    Article • January 2012, Springer Science + Business Media

    MD Ernesto Crisafulli, Professor Enrico M. Clini, stefania costi

  260. Rehabilitation, weaning and physical therapy strategies in chronic critically ill patients

    Article • European Respiratory Journal, December 2011, European Respiratory Society (ERS)

    Professor Enrico M. Clini

  261. Dynamic hyperinflation is associated with a poor cardiovascular response to exercise in COPD patients

    Article • December 2011, Springer Science + Business Media

    Professor Enrico M. Clini

  262. Exercise performance after standard rehabilitation in COPD patients with lung hyperinflation

    Article • Internal and Emergency Medicine, November 2011, Springer Science + Business Media

    Professor Enrico M. Clini

  263. Co-morbidities in chronic respiratory patients: limitations or opportunities for caring?

    Article • Journal of Medicine and the Person, October 2011, Springer Science + Business Media

    MD Ernesto Crisafulli, Professor Enrico M. Clini

  264. COPD and the metabolic syndrome: an intriguing association

    Article • Internal and Emergency Medicine, October 2011, Springer Science + Business Media

    MD Ernesto Crisafulli, Professor Enrico M. Clini

  265. Effects of beclomethasone/formoterol fixed combination on lung hyperinflation and dyspnea in COPD patients

    Article • International Journal of Chronic Obstructive Pulmonary Disease, October 2011, Taylor & Francis

    Professor Enrico M. Clini

  266. Energy Expenditure at Rest and during Walking in Patients with Chronic Respiratory Failure: A Prospective Two-Phase Case-Control Study

    Article • PLOS One, August 2011, PLOS

    Professor Enrico M. Clini

  267. Rehabilitation in COPD patients: evergreen in pneumology and beyond

    Article • European Respiratory Journal, August 2011, European Respiratory Society (ERS)

    Professor Enrico M. Clini

  268. Safety and Efficacy of Short-Term Intrapulmonary Percussive Ventilation in Patients With Bronchiectasis

    Article • Respiratory Care, July 2011, Daedalus Enterprises

    Professor Enrico M. Clini

  269. Selected clinical highlights from the 2010 ERS Congress in Barcelona

    Article • European Respiratory Journal, March 2011, European Respiratory Society (ERS)

    Professor Enrico M. Clini

  270. Complessità del paziente con insufficienza respiratoria cronica associata a BPCO

    Article • Italian Journal of Medicine, March 2011, PAGEPress Publications

    Professor Enrico M. Clini

  271. Functional Recovery Following Physical Training in Tracheotomized and Chronically Ventilated Patients

    Article • Respiratory Care, March 2011, Daedalus Enterprises

    Professor Enrico M. Clini, stefania costi

  272. Non-invasive ventilation in elderly patients with acute hypercapnic respiratory failure: a randomised controlled trial

    Article • Age and Ageing, February 2011, Oxford University Press (OUP)

    Professor Enrico M. Clini

  273. Non-invasive Ventilation and Weaning: Principles and Practice

    Article • September 2010, Taylor & Francis

    Professor Enrico M. Clini

  274. Early Rehabilitation

    Article • American Review of Respiratory Disease, May 2010, American Thoracic Society

    MD Ernesto Crisafulli, Professor Enrico M. Clini

  275. Efficacy of standard rehabilitation in COPD outpatients with comorbidities

    Article • European Respiratory Journal, April 2010, European Respiratory Society (ERS)

    Professor Enrico M. Clini

  276. Measures of dyspnea in pulmonary rehabilitation

    Article • Multidisciplinary Respiratory Medicine, January 2010, Springer Science + Business Media

    MD Ernesto Crisafulli, Professor Enrico M. Clini

  277. Lung function evaluation before surgery in lung cancer patients: how are recent advances put into practice? A survey among members of the European Society of Thoracic Surgeons (ESTS) and of the Thoracic Oncology Section of the European Respiratory Soci...

    Article • Interactive Cardiovascular and Thoracic Surgery, December 2009, Oxford University Press (OUP)

    Professor Enrico M. Clini

  278. Erratum to: Subjective Sleep Quality During Average Volume Assured Pressure Support (AVAPS) Ventilation in Patients with Hypercapnic COPD: A Physiological Pilot Study

    Article • Lung, October 2009, Springer Science + Business Media

    Professor Enrico M. Clini

  279. Effects of early inpatient rehabilitation after acute exacerbation of COPD

    Article • Respiratory Medicine, October 2009, Elsevier

    MD Ernesto Crisafulli, Professor Enrico M. Clini, stefania costi

  280. Patients’ characterization, hospital course and clinical outcomes in five Italian respiratory intensive care units

    Article • Intensive Care Medicine, September 2009, Springer Science + Business Media

    Professor Enrico M. Clini

  281. "ERS/ESTS CLINICAL GUIDELINES ON FITNESS FOR RADICAL THERAPY IN LUNG CANCER PATIENTS (SURGERY AND CHEMO-RADIOTHERAPY)". A. BRUNELLI, A. CHARLOUX, C.T. BOLLIGER, G. ROCCO, J-P. SCULIER, G. VARELA, M. LICKER, M.K. FERGUSON, C. FAIVRE-FINN, R.M. HUBER, E....

    Article • European Respiratory Journal, August 2009, European Respiratory Society (ERS)

    Professor Enrico M. Clini

  282. Last 3 months of life in home-ventilated patients: the family perception

    Article • European Respiratory Journal, August 2009, European Respiratory Society (ERS)

    Professor Enrico M. Clini

  283. Subjective Sleep Quality During Average Volume Assured Pressure Support (AVAPS) Ventilation in Patients with Hypercapnic COPD: A Physiological Pilot Study

    Article • Lung, August 2009, Springer Science + Business Media

    MD Ernesto Crisafulli, Professor Enrico M. Clini

  284. Effects of Unsupported Upper Extremity Exercise Training in Patients With COPD

    Article • CHEST Journal, August 2009, Elsevier

    MD Ernesto Crisafulli, Professor Enrico M. Clini, stefania costi

  285. Long-term Weight Loss and Maintenance in Morbidly Obese Individuals with Obstructive Sleep Apnea

    Article • American Review of Respiratory Disease, July 2009, American Thoracic Society

    Professor Enrico M. Clini

  286. The European Respiratory Society and European Society of Thoracic Surgeons clinical guidelines for evaluating fitness for radical treatment (surgery and chemoradiotherapy) in patients with lung cancer

    Article • European Journal of Cardio-Thoracic Surgery, July 2009, Oxford University Press (OUP)

    Professor Enrico M. Clini

  287. ERS/ESTS clinical guidelines on fitness for radical therapy in lung cancer patients (surgery and chemo-radiotherapy)

    Article • European Respiratory Journal, June 2009, European Respiratory Society (ERS)

    Professor Enrico M. Clini

  288. Short-term Efficacy of Upper-Extremity Exercise Training in Patients With Chronic Airway Obstruction: A Systematic Review

    Article • Physical Therapy, May 2009, Oxford University Press (OUP)

    Professor Enrico M. Clini, stefania costi

  289. Use of functional independence measure in rehabilitation of inpatients with respiratory failure

    Article • Respiratory Medicine, March 2009, Elsevier

    Professor Enrico M. Clini

  290. Exercise Capacity as a Pulmonary Rehabilitation Outcome

    Article • Respiration, January 2009, Karger Publishers

    MD Ernesto Crisafulli, Professor Enrico M. Clini

  291. Home-centred physical fitness programme in morbidly obese individuals: a randomized controlled trial

    Article • Clinical Rehabilitation, October 2008, SAGE Publications

    Professor Enrico M. Clini

  292. Role of hyperinflation vs. deflation on dyspnoea in severely to extremely obese subjects

    Article • Acta Physiologica, August 2008, Wiley

    Professor Enrico M. Clini

  293. Role of comorbidities in a cohort of patients with COPD undergoing pulmonary rehabilitation

    Article • Thorax, June 2008, BMJ

    Professor Enrico M. Clini, stefania costi

  294. Predictors of 6-Month Mortality in Elderly Patients with Mild Chronic Obstructive Pulmonary Disease Discharged from a Medical Ward After Acute Nonacidotic Exacerbation

    Article • Journal of the American Geriatrics Society, May 2008, Wiley

    Professor Enrico M. Clini

  295. Home Non-Invasive Mechanical Ventilation and Long-Term Oxygen Therapy in Stable Hypercapnic Chronic Obstructive Pulmonary Disease Patients: Comparison of Costs

    Article • Respiration, April 2008, Karger Publishers

    MD Ernesto Crisafulli, Professor Enrico M. Clini

  296. Indications and Physiological Basis of Rehabilitation in the ICU

    Article • March 2008, Taylor & Francis

    Professor Enrico M. Clini

  297. Nutrition in ICU

    Article • March 2008, Taylor & Francis

    Professor Enrico M. Clini

  298. Nonpharmacological treatment and relief of symptoms in COPD

    Article • European Respiratory Journal, March 2008, European Respiratory Society (ERS)

    Professor Enrico M. Clini

  299. Effectiveness of erdosteine in elderly patients with bronchiectasis and hypersecretion: A 15-day, prospective, parallel, open-label, pilot study

    Article • Clinical Therapeutics, September 2007, Elsevier

    Professor Enrico M. Clini, stefania costi

  300. Post-operative respiratory rehabilitation after lung resection for non-small cell lung cancer

    Article • Lung Cancer, August 2007, Elsevier

    Professor Enrico M. Clini

  301. Effects of a Walking Aid in COPD Patients Receiving Oxygen Therapy

    Article • CHEST Journal, April 2007, Elsevier

    Professor Enrico M. Clini, stefania costi

  302. Respiratory muscles training in COPD patients

    Article • International Journal of COPD, March 2007, Dove Medical Press

    MD Ernesto Crisafulli, Professor Enrico M. Clini, stefania costi

  303. Intrapulmonary percussive ventilation in tracheostomized patients: a randomized controlled trial

    Article • Intensive Care Medicine, October 2006, Springer Science + Business Media

    Professor Enrico M. Clini

  304. Maximal inspiratory and expiratory pressure measurement in tracheotomised patients

    Article • European Respiratory Journal, February 2006, European Respiratory Society (ERS)

    Professor Enrico M. Clini

  305. Repeated Pulmonary Rehabilitation in Severe and Disabled COPD Patients

    Article • Respiration, January 2006, Karger Publishers

    MD Ernesto Crisafulli, Professor Enrico M. Clini, stefania costi

  306. Inspiratory Muscle Training: A Way to Breathe More Easily

    Article • Respiration, January 2006, Karger Publishers

    Professor Enrico M. Clini, stefania costi

  307. EFFECTIVENESS OF A REHABILITATION PROGRAM IN MORBIDLY OBESE SUBJECTS WITH SLEEP DISTURBANCIES

    Article • CHEST Journal, October 2005, Elsevier

    Professor Enrico M. Clini

  308. Supported Arm Training in Patients Recently Weaned From Mechanical Ventilation

    Article • CHEST Journal, October 2005, Elsevier

    Professor Enrico M. Clini

  309. Early physiotherapy in the respiratory intensive care unit

    Article • Respiratory Medicine, September 2005, Elsevier

    Professor Enrico M. Clini

  310. Length and Clinical Effectiveness of Pulmonary Rehabilitation in Outpatients With Chronic Airway Obstruction

    Article • CHEST Journal, January 2005, Elsevier

    Professor Enrico M. Clini

  311. Inpatient pulmonary rehabilitation: does it make sense?

    Article • Chronic Respiratory Disease, January 2005, SAGE Publications

    Professor Enrico M. Clini

  312. Assessment of Physiologic Variables and Subjective Comfort Under Different Levels of Pressure Support Ventilation

    Article • CHEST Journal, September 2004, Elsevier

    Professor Enrico M. Clini

  313. Inspiratory muscle workload due to dynamic intrinsic PEEP in stable COPD patients: effects of two different settings of non-invasive pressure-support ventilation

    Article • Monaldi Archives for Chest Disease, June 2004, PAGEPress Publications

    Professor Enrico M. Clini

  314. Long-term mechanical ventilation and nutrition

    Article • Respiratory Medicine, May 2004, Elsevier

    Professor Enrico M. Clini

  315. Occupational Therapy and Pulmonary Rehabilitation of Disabled COPD Patients

    Article • Respiration, January 2004, Karger Publishers

    Professor Enrico M. Clini

  316. Effects of Respiratory Therapist-Directed Protocol on Prescription and Outcomes of Pulmonary Rehabilitation in COPD Inpatients

    Article • Respiration, January 2004, Karger Publishers

    Professor Enrico M. Clini

  317. The Italian multicentre study on noninvasive ventilation in chronic obstructive pulmonary disease patients

    Article • European Respiratory Journal, September 2002, European Respiratory Society (ERS)

    Professor Enrico M. Clini, Giancarlo Garuti

  318. Exhaled nitric oxide and exercise tolerance in severe COPD patients

    Article • Respiratory Medicine, May 2002, Elsevier

    Professor Enrico M. Clini

  319. In-Hospital Short-term Training Program for Patients With Chronic Airway Obstruction

    Article • CHEST Journal, November 2001, Elsevier

    Professor Enrico M. Clini

  320. Physiological Response to Pressure Support Ventilation Delivered before and after Extubation in Patients Not Capable of Totally Spontaneous Autonomous Breathing

    Article • American Review of Respiratory Disease, August 2001, American Thoracic Society

    Professor Enrico M. Clini

  321. Erratum

    Article • Respiratory Medicine, August 2001, Elsevier

    Professor Enrico M. Clini

  322. Comparison of Two Methods for Weaning Patients with Chronic Obstructive Pulmonary Disease Requiring Mechanical Ventilation for More Than 15 Days

    Article • American Review of Respiratory Disease, July 2001, American Thoracic Society

    Professor Enrico M. Clini

  323. Effect of pulmonary rehabilitation on exhaled nitric oxide in patients with chronic obstructive pulmonary disease

    Article • Thorax, July 2001, BMJ

    Professor Enrico M. Clini

  324. Exhaled nitric oxide in patients with PiZZ Phenotype-related α 1-anti-trypsin deficiency

    Article • Respiratory Medicine, June 2001, Elsevier

    Professor Enrico M. Clini

  325. The Appropriate Setting of Noninvasive Pressure Support Ventilation in Stable COPD Patients

    Article • CHEST Journal, November 2000, Elsevier

    Professor Enrico M. Clini

  326. Production of Endogenous Nitric Oxide in Chronic Obstructive Pulmonary Disease and Patients with Cor Pulmonale

    Article • American Review of Respiratory Disease, August 2000, American Thoracic Society

    Professor Enrico M. Clini

  327. Physiologic effects of early administered mask proportional assist ventilation in patients with chronic obstructive pulmonary disease and acute respiratory failure

    Article • Critical Care Medicine, June 2000, Wolters Kluwer Health

    Professor Enrico M. Clini

  328. Preliminary results on nursing workload in a dedicated weaning center

    Article • Intensive Care Medicine, June 2000, Springer Science + Business Media

    Professor Enrico M. Clini

  329. Endogenous nitric oxide in patients with chronic heart failure (CHF): relation to functional impairment and nitrate-containing therapies

    Article • International Journal of Cardiology, April 2000, Elsevier

    Professor Enrico M. Clini

  330. Exhaled Nitric Oxide and Exercise in Stable COPD Patients

    Article • CHEST Journal, March 2000, Elsevier

    Professor Enrico M. Clini

  331. Physiological effects of posture on mask ventilation in awake stable chronic hypercapnic COPD patients

    Article • European Respiratory Journal, September 1999, European Respiratory Society (ERS)

    Professor Enrico M. Clini

  332. DETECTION OF NITRIC OXIDE IN EXHALED AIR OF DIFFERENT ANIMAL SPECIES USING A CLINICAL CHEMILUMINESCENCE ANALYSER

    Article • Pharmacological Research, March 1999, Elsevier

    Professor Enrico M. Clini

  333. Differences in spontaneous breathing pattern and mechanics in patients with severe COPD recovering from acute excerbation

    Article • European Respiratory Journal, February 1999, European Respiratory Society (ERS)

    Professor Enrico M. Clini

  334. Outcome of COPD patients performing nocturnal non-invasive mechanical ventilation

    Article • Respiratory Medicine, October 1998, Elsevier

    Professor Enrico M. Clini

  335. Acute effects of deep diaphragmatic breathing in COPD patients with chronic respiratory insufficiency

    Article • European Respiratory Journal, February 1998, European Respiratory Society (ERS)

    Professor Enrico M. Clini

  336. Breathing pattern and respiratory mechanics in patients with amyotrophic lateral sclerosis

    Article • European Respiratory Journal, July 1997, European Respiratory Society (ERS)

    Professor Enrico M. Clini

  337. Evaluation in pulmonary rehabilitation

    Article • Respiratory Medicine, August 1996, Elsevier

    Professor Enrico M. Clini

  338. Acute exacerbations in patients with COPD: predictors of need for mechanical ventilation

    Article • European Respiratory Journal, June 1996, European Respiratory Society (ERS)

    Professor Enrico M. Clini

  339. Association therapy as a prognostic factor in deep fungal infection complicating oncohaematological diseases

    Article • Supportive Care in Cancer, November 1994, Springer Science + Business Media

    Professor Enrico M. Clini

  340. Transcutaneous Partial Oxygen Tension and Lung Mechanics During Methacholine Inhaled Challenge

    Article • CHEST Journal, June 1994, Elsevier

    Professor Enrico M. Clini

  341. Ceftizoxime in Lower Respiratory Tract Infection

    Article • Drug Investigation, January 1992, Springer Science + Business Media

    Professor Enrico M. Clini