All Stories

  1. (Poly)phenols and brain health – beyond their antioxidant capacity
  2. Dietary (Poly)phenols and the Gut–Brain Axis in Ageing
  3. Circulatory dietary and gut-derived metabolites predict preclinical Alzheimer’s disease
  4. Do microbes play a role in Alzheimer's disease?
  5. Refined diet consumption increases neuroinflammatory signalling through bile acid dysmetabolism
  6. Unravelling phenolic metabotypes in the frame of the COMBAT study, a randomized, controlled trial with cranberry supplementation
  7. Reply to M. Plourde and M. Stiffel
  8. Personality, dietary identity, mental and sleep health in vegans and vegetarians: A preliminary cross‐sectional study
  9. A combined DHA-rich fish oil and cocoa flavanols intervention does not improve cognition or brain structure in older adults with memory complaints: results from the CANN randomized, controlled parallel-design study
  10. The Influence of APOE Genotype, DHA, and Flavanol Intervention on Brain DHA and Lipidomics Profile in Aged Transgenic Mice
  11. Data from A Ketogenic Diet in Combination with Gemcitabine Increases Survival in Pancreatic Cancer KPC Mice
  12. Data from A Ketogenic Diet in Combination with Gemcitabine Increases Survival in Pancreatic Cancer KPC Mice
  13. Supplementary Table S1, Figures S1-S8 from A Ketogenic Diet in Combination with Gemcitabine Increases Survival in Pancreatic Cancer KPC Mice
  14. Supplementary Table S1, Figures S1-S8 from A Ketogenic Diet in Combination with Gemcitabine Increases Survival in Pancreatic Cancer KPC Mice
  15. Natural Products and Neuroprotection 3.0
  16. Cerebrovascular damage caused by the gut microbe-derived uraemic toxinp-cresol sulfate is prevented by blockade of the epidermal growth factor receptor
  17. Wholegrain fermentation affects gut microbiota composition, phenolic acid metabolism and pancreatic beta cell function in a rodent model of type 2 diabetes
  18. Multi-nutrient interventions and cognitive ageing: are we barking up the right tree?
  19. A Ketogenic Diet in Combination with Gemcitabine Increases Survival in Pancreatic Cancer KPC Mice
  20. (-)-Epicatechin mitigates anxiety-related behavior in a mouse model of high fat diet-induced obesity
  21. The EAT–Lancet reference diet and cognitive function across the life course
  22. Systematic analysis of nutrigenomic effects of polyphenols related to cardiometabolic health in humans – Evidence from untargeted mRNA and miRNA studies
  23. Editorial: Polyphenols' action on the brain
  24. Microbial-derived metabolites as a risk factor of age-related cognitive decline and dementia
  25. Chronic Consumption of Cranberries (Vaccinium macrocarpon) for 12 Weeks Improves Episodic Memory and Regional Brain Perfusion in Healthy Older Adults: A Randomised, Placebo-Controlled, Parallel-Groups Feasibility Study
  26. The role of the mucin-glycan foraging Ruminococcus gnavus in the communication between the gut and the brain
  27. Fecal microbiota transfer between young and aged mice reverses hallmarks of the aging gut, eye, and brain
  28. DHA-Enriched Fish Oil Ameliorates Deficits in Cognition Associated with Menopause and the APOE4 Genotype in Rodents
  29. Circulating Human Serum Metabolites Derived from the Intake of a Saffron Extract (Safr’InsideTM) Protect Neurons from Oxidative Stress: Consideration for Depressive Disorders
  30. The microbiota–gut–brain axis: pathways to better brain health. Perspectives on what we know, what we need to investigate and how to put knowledge into practice
  31. The microRNA-455 Null Mouse Has Memory Deficit and Increased Anxiety, Targeting Key Genes Involved in Alzheimer’s Disease
  32. Saffron extract (Safr'Inside™) improves anxiety related behaviour in a mouse model of low-grade inflammation through the modulation of the microbiota and gut derived metabolites
  33. Cognitive Ageing: The Role of Nutrition
  34. Differential Influence of Soluble Dietary Fibres on Intestinal and Hepatic Carbohydrate Response
  35. Regulation of blood–brain barrier integrity by microbiome-associated methylamines and cognition by trimethylamine N-oxide
  36. Anthocyanins Promote Learning through Modulation of Synaptic Plasticity Related Proteins in an Animal Model of Ageing
  37. Systematic Bioinformatic Analyses of Nutrigenomic Modifications by Polyphenols Associated with Cardiometabolic Health in Humans—Evidence from Targeted Nutrigenomic Studies
  38. Molecular Determinants of the Cardiometabolic Improvements of Dietary Flavanols Identified by an Integrative Analysis of Nutrigenomic Data from a Systematic Review of Animal Studies
  39. Acute Effects of Polyphenols on Human Attentional Processes: A Systematic Review and Meta-Analysis
  40. Therapeutic Opportunities for Food Supplements in Neurodegenerative Disease and Depression
  41. APOE4 genotype exacerbates the impact of menopause on cognition and synaptic plasticity in APOE‐TR mice
  42. Effects of Saffron Extract Supplementation on Mood, Well-Being, and Response to a Psychosocial Stressor in Healthy Adults: A Randomized, Double-Blind, Parallel Group, Clinical Trial
  43. Regulation of blood–brain barrier integrity and cognition by the microbiome-associated methylamines trimethylamine-N-oxide and trimethylamine
  44. Faecal microbiota transplant from aged donor mice affects spatial learning and memory via modulating hippocampal synaptic plasticity- and neurotransmission-related proteins in young recipients
  45. Nutrition and the ageing brain: Moving towards clinical applications
  46. The Effect of Long-Term Aronia melanocarpa Extract Supplementation on Cognitive Performance, Mood, and Vascular Function: A Randomized Controlled Trial in Healthy, Middle-Aged Individuals
  47. The role of diet in preventing and reducing cognitive decline
  48. (-)-Epicatechin and NADPH oxidase inhibitors prevent bile acid-induced Caco-2 monolayer permeabilization through ERK1/2 modulation
  49. Acute Intake of a Grape and Blueberry Polyphenol-Rich Extract Ameliorates Cognitive Performance in Healthy Young Adults During a Sustained Cognitive Effort
  50. Faecal microbiota transplant from aged donor mice affects spatial learning and memory via modulating hippocampal synaptic plasticity- and neurotransmission-related proteins in young recipients
  51. Natural Products and Neuroprotection
  52. Inorganic nitrate and nitrite supplementation fails to improve skeletal muscle mitochondrial efficiency in mice and humans
  53. Altered SPMs and age-associated decrease in brain DHA in APOE4 female mice
  54. APOE genotype influences the gut microbiome structure and function in humans and mice: relevance for Alzheimer’s disease pathophysiology
  55. Wine Polyphenols and Neurodegenerative Diseases: An Update on the Molecular Mechanisms Underpinning Their Protective Effects
  56. Association between Apolipoprotein E genotype and the gut microbiome composition in humans and mice
  57. The impact of cranberries on microbiome and brain in healthy ageing
  58. Polyphenols Targeting Brain Cells Longevity, Brain’s Redox Status, and Neurodegenerative Diseases
  59. Inhibition of PP2A by hesperetin may contribute to Akt and ERK1/2 activation status in cortical neurons
  60. Validation of control genes and a standardised protocol for quantifying gene expression in the livers of C57BL/6 and ApoE−/− mice
  61. The effect of APOE genotype on Alzheimer’s disease risk is influenced by sex and DHA status
  62. Impact of Flavonoids on Cellular and Molecular Mechanisms Underlying Age-Related Cognitive Decline and Neurodegeneration
  63. Do anthocyanins in purple tomatoes reduce the risk of cardiovascular disease?–Retraction
  64. Poor cognitive ageing: Vulnerabilities, mechanisms and the impact of nutritional interventions
  65. n-3 Fatty acids combined with flavan-3-ols prevent steatosis and liver injury in a murine model of NAFLD
  66. The Cognitive Ageing, Nutrition and Neurogenesis (CANN) trial: Design and progress
  67. Nutrition for the ageing brain: Towards evidence for an optimal diet
  68. The effect of dietary fish oil on weight gain and insulin sensitivity is dependent on APOE genotype in humanized targeted replacement mice
  69. Polyphenols and brain health
  70. Neuroprotective Effects of Polyphenols in Aging and Age-Related Neurological Disorders
  71. High-flavonoid intake induces cognitive improvements linked to changes in serum brain-derived neurotrophic factor: Two randomised, controlled trials
  72. Differential effects of EPA versus DHA on postprandial vascular function and the plasma oxylipin profile in men
  73. A Transgenic Camelina sativa Seed Oil Effectively Replaces Fish Oil as a Dietary Source of Eicosapentaenoic Acid in Mice
  74. Neuroprotective Effects Associated with Wine and Its Phenolic Constituents
  75. Polyphenols and non-alcoholic fatty liver disease: impact and mechanisms
  76. Neuroinflammatory processes in cognitive disorders: Is there a role for flavonoids and n-3 polyunsaturated fatty acids in counteracting their detrimental effects?
  77. Low-grade inflammation, diet composition and health: current research evidence and its translation
  78. Anthocyanins do not influence long-chain n-3 fatty acid status: studies in cells, rodents and humans
  79. Dietary Levels of Pure Flavonoids Improve Spatial Memory Performance and Increase Hippocampal Brain-Derived Neurotrophic Factor
  80. Do anthocyanins in purple tomatoes reduce the risk of cardiovascular disease?
  81. Dietary Polyphenols and Their Effects on Cell Biochemistry and Pathophysiology 2014
  82. The neurotoxicity of 5-S-cysteinyldopamine is mediated by the early activation of ERK1/2 followed by the subsequent activation of ASK1/JNK1/2 pro-apoptotic signalling
  83. Bioavailability, bioactivity and impact on health of dietary flavonoids and related compounds: an update
  84. Polyphénols et neuroprotection : où en sommes-nous aujourd’hui ?
  85. SULFORAPHANE PROTECTS CORTICAL NEURONS AGAINST ENDOGENOUS NEUROTOXINS IN A MODEL OF PARKINSON'S DISEASE
  86. A role for hippocampal PSA-NCAM and NMDA-NR2B receptor function in flavonoid-induced spatial memory improvements in young rats
  87. The impact of fish‐oil fatty acids on postprandial vascular reactivity (959.22)
  88. Plant Polyphenols as Dietary Modulators of Brain Functions
  89. The Impact of Gastrointestinal Modifications, Blood-Brain Barrier Transport, and Intracellular Metabolism on Polyphenol Bioavailability
  90. Redox Signaling in Degenerative Diseases: From Molecular Mechanisms to Health Implications
  91. Dietary Polyphenols and Their Effects on Cell Biochemistry and Pathophysiology 2013
  92. The impact of Champagne wine consumption on vascular and cognitive functions
  93. Effect of flavonoids on learning, memory and neurocognitive performance: relevance and potential implications for Alzheimer's disease pathophysiology
  94. Phenolic Acid Intake, DeliveredViaModerate Champagne Wine Consumption, Improves Spatial Working MemoryViathe Modulation of Hippocampal and Cortical Protein Expression/Activation
  95. Dietary Levels of Pure Flavonoids Improve Spatial Memory Performance and Increase Hippocampal Brain-Derived Neurotrophic Factor
  96. Effect of Cultivar Type and Ripening on the Polyphenol Content of Date Palm Fruit
  97. Potential Neuroprotective Actions of Dietary Flavonoids
  98. The effect of anthocyanin consumption on blood and tissue levels of fatty acids in animals and humans
  99. The impact of polyphenols and flavonoids on memory, learning and neuro-cognitive performance
  100. Blueberry supplementation induces spatial memory improvements and region-specific regulation of hippocampal BDNF mRNA expression in young rats
  101. Flavonoids and Neuroinflammation
  102. Polyphenols
  103. Neuroinflammation: Modulation by flavonoids and mechanisms of action
  104. Regulation of NF-κB activity in astrocytes: effects of flavonoids at dietary-relevant concentrations
  105. Inhibition of colon adenocarcinoma cell proliferation by flavonols is linked to a G2/M cell cycle block and reduction in cyclin D1 expression
  106. Dietary Polyphenols and Their Effects on Cell Biochemistry and Pathophysiology
  107. Dietary Polyphenols as Modulators of Brain Functions: Biological Actions and Molecular Mechanisms Underpinning Their Beneficial Effects
  108. Neuroinflammation and the APOε genotype: Implications for Alzheimer's disease and modulation by dietary flavonoids and n-3 polyunsaturated fatty acids
  109. Potential Health Effects of Champagne Wine Consumption
  110. Absorption and metabolism of olive oil secoiridoids in the small intestine
  111. Neuroprotective actions of astaxanthin in cultured cortical neurones
  112. The effect of ripening on the polyphenol profile of commonly consumed varieties of date palm fruits
  113. Assessment of the anthocyanidin content of common fruits and development of a test diet rich in a range of anthocyanins
  114. Polyphenols and Human Health: Prevention of Disease and Mechanisms of Action
  115. Caffeic acid, tyrosol and p-coumaric acid are potent inhibitors of 5-S-cysteinyl-dopamine induced neurotoxicity
  116. Sulforaphane protects cortical neurons against 5-S-cysteinyl-dopamine-induced toxicity through the activation of ERK1/2, Nrf-2 and the upregulation of detoxification enzymes
  117. Phytochemicals from beer: identification, antioxidant activity, absorption and bioactivity
  118. The inhibitory effects of berry-derived flavonoids against neurodegenerative processes
  119. Involvement of ERK, Akt and JNK signalling in H2O2-induced cell injury and protection by hydroxytyrosol and its metabolite homovanillic alcohol
  120. Flavonoids and cognition: The molecular mechanisms underlying their behavioural effects
  121. Moderate Champagne consumption promotes an acute improvement in acute endothelial-independent vascular function in healthy human volunteers
  122. Dietary Flavonoids as Neuroprotective Agents
  123. The impact of flavonoids on spatial memory in rodents: from behaviour to underlying hippocampal mechanisms
  124. Hydroxytyrosol inhibits the proliferation of human colon adenocarcinoma cells through inhibition of ERK1/2 and cyclin D1
  125. The citrus flavanone naringenin inhibits inflammatory signalling in glial cells and protects against neuroinflammatory injury
  126. The neuroprotective potential of flavonoids: a multiplicity of effects
  127. Glial metabolism of quercetin reduces its neurotoxic potential
  128. Peroxynitrite induced formation of the neurotoxins 5-S-cysteinyl-dopamine and DHBT-1: Implications for Parkinson’s disease and protection by polyphenols
  129. Blueberry-induced changes in spatial working memory correlate with changes in hippocampal CREB phosphorylation and brain-derived neurotrophic factor (BDNF) levels
  130. Substrate specificity of human glutamine transaminase K as an aminotransferase and as a cysteine S-conjugate β-lyase
  131. Inhibition of cellular proliferation by the genistein metabolite 5,7,3′,4′-tetrahydroxyisoflavone is mediated by DNA damage and activation of the ATR signalling pathway
  132. Activation of pro-survival Akt and ERK1/2 signalling pathways underlie the anti-apoptotic effects of flavanones in cortical neurons
  133. Inhibition of the formation of the neurotoxin 5-S-cysteinyl-dopamine by polyphenols
  134. Inhibition of p38/CREB phosphorylation and COX-2 expression by olive oil polyphenols underlies their anti-proliferative effects
  135. Neuroinflammation and its Modulation by Flavonoids
  136. Champagne Wine Polyphenols Protect Primary Cortical Neurons against Peroxynitrite-Induced Injury
  137. The reaction of flavonoid metabolites with peroxynitrite
  138. The intracellular genistein metabolite 5,7,3′,4′-tetrahydroxyisoflavone mediates G2-M cell cycle arrest in cancer cells via modulation of the p38 signaling pathway
  139. Activation of glutathione peroxidase via Nrf1 mediates genistein’s protection against oxidative endothelial cell injury
  140. The beneficial effects of dietary flavonoids: sources, bioavailability and biological functions.