All Stories

  1. Vincristine treatment reverses podocyte damage in focal segmental glomerulosclerosis

    Article • November 2024, Cold Spring Harbor Laboratory Press

    David Long

  2. Reversal of elevatedGli3in Autosomal Recessive Polycystic Kidney Disease does not alter cystogenesis

    Article • September 2024, Cold Spring Harbor Laboratory Press

    David Long

  3. Cell Catcher: A New Method to Extract and Preserve Live Renal Cells from Urine

    Article • Kidney360, September 2024, Wolters Kluwer Health

    David Long

  4. Single‐cell transcriptomics identifies aberrant glomerular angiogenic signalling in the early stages of WT1 kidney disease

    Article • The Journal of Pathology, August 2024, Wiley

    David Long

  5. SGLT1 contributes to glucose-mediated exacerbation of ischemia–reperfusion injury in ex vivo rat heart

    Article • Basic Research in Cardiology, August 2024, Springer Science + Business Media

    David Long

  6. Cardiotrophin‐1 therapy reduces disease severity in a murine model of glomerular disease

    Article • Physiological Reports, July 2024, Wiley

    David Long

  7. A unique subset of pericystic endothelium associates with aberrant microvascular remodelling and impaired blood perfusion early in polycystic kidney disease

    Article • March 2024, Cold Spring Harbor Laboratory Press

    David Long

  8. A microfluidic platform integrating functional vascularized organoids-on-chip

    Article • Nature Communications, February 2024, Springer Science + Business Media

    David Long

  9. Cell Catcher: a new method to extract and preserve live renal cells from urine

    Article • September 2023, Cold Spring Harbor Laboratory Press

    David Long

  10. Mapping the blood vasculature in an intact human kidney using hierarchical phase-contrast tomography

    Article • March 2023, Cold Spring Harbor Laboratory Press

    David Long

  11. Hyperglycemic exacerbation of myocardial infarction through SGLT1 - a glucose paradox

    Article • March 2023, Cold Spring Harbor Laboratory Press

    David Long

  12. Three-dimensional imaging and single-cell transcriptomics of the human kidney implicate perturbation of lymphatics in alloimmunity

    Article • October 2022, Cold Spring Harbor Laboratory Press

    David Long

  13. Systemic gene therapy with thymosin β4 alleviates glomerular injury in mice

    Article • Scientific Reports, July 2022, Springer Science + Business Media

    David Long

  14. The timing of auditory sensory deficits in Norrie disease has implications for therapeutic intervention

    Article • JCI Insight, February 2022, American Society for Clinical Investigation

    David Long

  15. ­­­Kidney organoids recapitulate human basement membrane assembly in health and disease

    Article • eLife, January 2022, eLife

    David Long

  16. Imaging intact human organs with local resolution of cellular structures using hierarchical phase-contrast tomography

    Article • Nature Chemical Biology, November 2021, Springer Science + Business Media

    David Long

  17. Experimental long-term diabetes mellitus alters the transcriptome and biomechanical properties of the rat urinary bladder

    Article • Scientific Reports, July 2021, Springer Science + Business Media

    David Long

  18. Identification of an Altered Matrix Signature in Kidney Aging and Disease

    Article • Journal of the American Society of Nephrology, May 2021, American Society of Nephrology

    David Long

  19. Systemic gene therapy with thymosin β4 alleviates glomerular injury in mice

    Article • May 2021, Cold Spring Harbor Laboratory Press

    David Long

  20. Mechanisms and cell lineages in lymphatic vascular development

    Article • Angiogenesis, April 2021, Springer Science + Business Media

    David Long

  21. The Biological Significance and Implications of Planar Cell Polarity for Nephrology

    Article • Frontiers in Physiology, February 2021, Frontiers

    David Long

  22. Multiscale three-dimensional imaging of intact human organs down to the cellular scale using hierarchical phase-contrast tomography

    Article • February 2021, Cold Spring Harbor Laboratory Press

    David Long

  23. Antenatal biological models in the characterization and research of congenital lower urinary tract disorders

    Article • Journal of Pediatric Urology, November 2020, Elsevier

    David Long

  24. Endothelial-epithelial communication in polycystic kidney disease: Role of vascular endothelial growth factor signalling

    Article • Cellular Signalling, August 2020, Elsevier

    David Long

  25. Pseudouridylation defect due to DKC1 and NOP10 mutations causes nephrotic syndrome with cataracts, hearing impairment, and enterocolitis

    Article • Proceedings of the National Academy of Sciences, June 2020, Proceedings of the National Academy of Sciences

    David Long, Kazunori Tomita

  26. Beyond a Passive Conduit: Implications of Lymphatic Biology for Kidney Diseases

    Article • Journal of the American Society of Nephrology, April 2020, American Society of Nephrology

    David Long

  27. Free 25-hydroxyvitamin-D concentrations are lower in children with renal transplant compared with chronic kidney disease

    Article • Pediatric Nephrology, January 2020, Springer Science + Business Media

    David Long, Dr Evgenia Preka

  28. Spatiotemporal dynamics and heterogeneity of renal lymphatics in mammalian development and cystic kidney disease

    Article • eLife, December 2019, eLife

    David Long

  29. Generating Mutant Renal Cell Lines Using CRISPR Technologies

    Article • November 2019, Springer Science + Business Media

    David Long, Marian Seda

  30. Tissue Clearing and Deep Imaging of the Kidney Using Confocal and Two-Photon Microscopy

    Article • November 2019, Springer Science + Business Media

    David Long

  31. Overexpression of Circulating Soluble Nogo-B Improves Diabetic Kidney Disease by Protecting the Vasculature

    Article • Diabetes, June 2019, American Diabetes Association

    luigi gnudi, David Long

  32. Arterial “inflammaging” drives vascular calcification in children on dialysis

    Article • Kidney International, April 2019, Elsevier

    David Long

  33. SGLT2 Inhibitor, Canagliflozin, Attenuates Myocardial Infarction in the Diabetic and Nondiabetic Heart

    Article • JACC Basic to Translational Science, February 2019, Elsevier

    David Long

  34. Planar cell polarity in organ formation

    Article • Current Opinion in Cell Biology, December 2018, Elsevier

    David Long

  35. Vangl2, a planar cell polarity molecule, is implicated in irreversible and reversible kidney glomerular injury

    Article • The Journal of Pathology, November 2018, Wiley

    David Long

  36. In vivo three-dimensional photoacoustic imaging of the renal vasculature in preclinical rodent models

    Article • AJP Renal Physiology, June 2018, American Physiological Society

    David Long

  37. Thymosin-β4: A key modifier of renal disease

    Article • Expert Opinion on Biological Therapy, May 2018, Taylor & Francis

    David Long

  38. Lithium induces mesenchymal-epithelial differentiation during human kidney development by activation of the Wnt signalling system

    Article • Cell Death Discovery, February 2018, Springer Science + Business Media

    David Long

  39. HeterozygousVangl2Looptailmice reveal novel roles for the planar cell polarity pathway in adult lung homeostasis and repair

    Article • Disease Models & Mechanisms, February 2017, The Company of Biologists

    David Long, Darcy Wagner

  40. Planar cell polarity genes Celsr1 and Vangl2 are necessary for kidney growth, differentiation, and rostrocaudal patterning

    Article • Kidney International, December 2016, Elsevier

    David Long

  41. Vascular growth factors play critical roles in kidney glomeruli

    Article • Clinical Science, November 2015, Portland Press Ltd.

    David Long

  42. The role of thymosin-β4 in kidney disease

    Article • Expert Opinion on Biological Therapy, June 2015, Informa Healthcare

    David Long

  43. Vascular Endothelial Growth Factor C for Polycystic Kidney Diseases

    Article • Journal of the American Society of Nephrology, June 2015, American Society of Nephrology

    David Long

  44. HDL in Children with CKD Promotes Endothelial Dysfunction and an Abnormal Vascular Phenotype

    Article • Journal of the American Society of Nephrology, May 2014, American Society of Nephrology

    David Long

  45. Planar cell polarity and the kidney

    Article • Nephrology Dialysis Transplantation, November 2013, Oxford University Press (OUP)

    David Long

  46. Targeted Glomerular Angiopoietin-1 Therapy for Early Diabetic Kidney Disease

    Article • Journal of the American Society of Nephrology, September 2013, American Society of Nephrology

    David Long

  47. Albuminuria is associated with too few glomeruli and too much testosterone

    Article • Kidney International, June 2013, Elsevier

    David Long

  48. Circulating Angiopoietin-2 Is a Marker for Early Cardiovascular Disease in Children on Chronic Dialysis

    Article • PLoS ONE, February 2013, PLOS

    David Long

  49. Mechanistic Insights into Vascular Calcification in CKD

    Article • Journal of the American Society of Nephrology, November 2012, American Society of Nephrology

    David Long

  50. Angiogenesis and autosomal dominant polycystic kidney disease

    Article • Pediatric Nephrology, September 2012, Springer Science + Business Media

    David Long

  51. The renal archaeologist: digging for clues in archived tissues to understand diabetic kidney disease

    Article • Nephrology Dialysis Transplantation, February 2012, Oxford University Press (OUP)

    David Long

  52. Restoring the renal microvasculature to treat chronic kidney disease

    Article • Nature Reviews Nephrology, February 2012, Springer Science + Business Media

    David Long

  53. An unusual case of pediatric shortness of breath—questions

    Article • Pediatric Nephrology, October 2011, Springer Science + Business Media

    David Long

  54. Selective Stimulation of VEGFR2 Accelerates Progressive Renal Disease

    Article • American Journal Of Pathology, July 2011, Elsevier

    David Long

  55. Modified Citrus Pectin Reduces Galectin-3 Expression and Disease Severity in Experimental Acute Kidney Injury

    Article • PLoS ONE, April 2011, PLOS

    David Long

  56. The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation

    Article • Human Molecular Genetics, September 2010, Oxford University Press (OUP)

    David Long

  57. Mutations in HPSE2 Cause Urofacial Syndrome

    Article • The American Journal of Human Genetics, June 2010, Elsevier

    David Long

  58. Corticosteroid-induced kidney dysmorphogenesis is associated with deregulated expression of known cystogenic molecules, as well as indian hedgehog

    Article • AJP Renal Physiology, February 2010, American Physiological Society

    David Long

  59. Sphingosine kinase-1: a potential mediator of renal fibrosis

    Article • Kidney International, October 2009, Elsevier

    David Long

  60. Abnormal Angiogenesis in Diabetic Nephropathy

    Article • Diabetes, June 2009, American Diabetes Association

    David Long

  61. Unraveling the Genetic Landscape of Bladder Development in Mice

    Article • The Journal of Urology, May 2009, Wolters Kluwer Health

    David Long

  62. HNF1BMutations Associate with Hypomagnesemia and Renal Magnesium Wasting

    Article • Journal of the American Society of Nephrology, April 2009, American Society of Nephrology

    David Long

  63. Angiostatin overexpression is associated with an improvement in chronic kidney injury by an anti-inflammatory mechanism

    Article • AJP Renal Physiology, January 2009, American Physiological Society

    David Long

  64. Roles of Angiopoietins in Kidney Development and Disease: Figure 1.

    Article • Journal of the American Society of Nephrology, September 2008, American Society of Nephrology

    David Long

  65. Teashirt 3 is necessary for ureteral smooth muscle differentiation downstream of SHH and BMP4

    Article • Development, August 2008, The Company of Biologists

    David Long

  66. Angiopoietin-1 therapy enhances fibrosis and inflammation following folic acid-induced acute renal injury

    Article • Kidney International, August 2008, Elsevier

    David Long

  67. Podocyte-Specific Expression of Angiopoietin-2 Causes Proteinuria and Apoptosis of Glomerular Endothelia

    Article • Journal of the American Society of Nephrology, July 2007, American Society of Nephrology

    David Long

  68. Microarray interrogation of human metanephric mesenchymal cells highlights potentially important molecules in vivo

    Article • Physiological Genomics, January 2007, American Physiological Society

    David Long

  69. Vascular endothelial growth factor administration does not improve microvascular disease in the salt-dependent phase of post-angiotensin II hypertension

    Article • AJP Renal Physiology, December 2006, American Physiological Society

    David Long

  70. Experimental short-term fetal bladder outflow obstruction: I. Morphology and cell biology associated with urinary flow impairment

    Article • Journal of Pediatric Urology, August 2006, Elsevier

    David Long

  71. Vascular endothelial growth factor stimulates embryonic urinary bladder development in organ culture

    Article • BJU International, July 2006, Wiley

    David Long

  72. Human Vascular Smooth Muscle Cells Express a Urate Transporter

    Article • Journal of the American Society of Nephrology, June 2006, American Society of Nephrology

    David Long

  73. Loss of nitric oxide and endothelial-derived hyperpolarizing factor-mediated responses in aging

    Article • Kidney International, November 2005, Elsevier

    David Long

  74. IL-10 Suppresses Chemokines, Inflammation, and Fibrosis in a Model of Chronic Renal Disease

    Article • Journal of the American Society of Nephrology, October 2005, American Society of Nephrology

    David Long

  75. How Does Angiotensin II Cause Renal Injury?

    Article • Hypertension, April 2004, Wolters Kluwer Health

    David Long

  76. Angiopoietin correlates with glomerular capillary loss in anti-glomerular basement membrane glomerulonephritis

    Article • Kidney International, June 2002, Elsevier

    David Long