All Stories

  1. Food deprivation increases hepatic hepcidin expression and can overcome the effect of Hfe deletion in male mice

    Article • The FASEB Journal, May 2018, Wiley

    Dr David M Frazer

  2. Hepcidin independent iron recycling in a mouse model of β-thalassaemia intermedia

    Article • British Journal of Haematology, July 2016, Wiley

    Dr David M Frazer

  3. Dietary iron depletion at weaning imprints low microbiome diversity and this is not recovered with oral nano Fe(III)

    Article • MicrobiologyOpen, December 2014, Wiley

    Dr David M Frazer

  4. Nanoparticulate iron(III) oxo-hydroxide delivers safe iron that is well absorbed and utilised in humans

    Article • Nanomedicine Nanotechnology Biology and Medicine, November 2014, Elsevier

    Dr David M Frazer

  5. The Multicopper Ferroxidase Hephaestin Enhances Intestinal Iron Absorption in Mice

    Article • PLoS ONE, June 2014, PLOS

    Dr David M Frazer

  6. Ferroportin mediates the intestinal absorption of iron from a nanoparticulate ferritin core mimetic in mice

    Article • The FASEB Journal, April 2014, Wiley

    Dr David M Frazer

  7. The regulation of iron transport

    Article • BioFactors, October 2013, Wiley

    Dr David M Frazer

  8. Sustained expression of heme oxygenase-1 alters iron homeostasis in nonerythroid cells

    Article • Free Radical Biology and Medicine, July 2012, Elsevier

    Dr David M Frazer

  9. Stimulated erythropoiesis with secondary iron loading leads to a decrease in hepcidin despite an increase in bone morphogenetic protein 6 expression

    Article • British Journal of Haematology, March 2012, Wiley

    Dr David M Frazer

  10. Reduced Expression of Ferroportin-1 Mediates Hyporesponsiveness of Suckling Rats to Stimuli That Reduce Iron Absorption

    Article • Gastroenterology, July 2011, Elsevier

    Dr David M Frazer

  11. Intestinal iron absorption during suckling in mammals

    Article • BioMetals, February 2011, Springer Science + Business Media

    Dr David M Frazer

  12. Severe iron deficiency blunts the response of the iron regulatory gene Hamp and pro-inflammatory cytokines to lipopolysaccharide

    Article • Haematologica, May 2010, Ferrata Storti Foundation (Haematologica)

    Dr David M Frazer

  13. 926 Reduced Ferroportin Protein Expression Explains Why Intestinal Iron Absorption in the Neonatal Rat is Hyporesponsive to Stimuli That Reduce Absorption in Adult Animals

    Article • Gastroenterology, May 2010, Elsevier

    Dr David M Frazer

  14. Combined deletion of Hfe and transferrin receptor 2 in mice leads to marked dysregulation of hepcidin and iron overload

    Article • Hepatology, October 2009, Wiley

    Dr David M Frazer, Professor Nathan Subramaniam

  15. Iron absorption and metabolism

    Article • Current Opinion in Gastroenterology, March 2009, Wolters Kluwer Health

    Dr David M Frazer

  16. How much iron is too much?

    Article • Expert Review of Gastroenterology & Hepatology, June 2008, Taylor & Francis

    Dr David M Frazer, Professor Nathan Subramaniam

  17. 984 Suppression of LPS and IL-6 Signaling By Iron Deficiency Alters Expression of the Intestinal Iron Absorption Regulator Hepcidin

    Article • Gastroenterology, April 2008, Elsevier

    Dr David M Frazer

  18. Elevated iron absorption in the neonatal rat reflects high expression of iron transport genes in the distal alimentary tract

    Article • AJP Gastrointestinal and Liver Physiology, July 2007, American Physiological Society

    Dr David M Frazer

  19. Regulation of systemic iron homeostasis: how the body responds to changes in iron demand

    Article • BioMetals, February 2007, Springer Science + Business Media

    Dr David M Frazer

  20. Iron metabolism meets signal transduction

    Article • Nature Genetics, May 2006, Springer Science + Business Media

    Dr David M Frazer

  21. The role of duodenal cytochrome b in intestinal iron absorption remains unclear

    Article • Blood, December 2005, American Society of Hematology

    Dr David M Frazer

  22. Iron Imports. I. Intestinal iron absorption and its regulation: Fig. 1.

    Article • AJP Gastrointestinal and Liver Physiology, September 2005, American Physiological Society

    Dr David M Frazer

  23. Recent advances in intestinal iron transport

    Article • Current Gastroenterology Reports, September 2005, Springer Science + Business Media

    Dr David M Frazer

  24. Mechanisms of Haem and Non-Haem Iron Absorption: Lessons from Inherited Disorders of Iron Metabolism

    Article • BioMetals, August 2005, Springer Science + Business Media

    Dr David M Frazer

  25. Systemic Regulation of Intestinal Iron Absorption

    Article • IUBMB Life, July 2005, Wiley

    Dr David M Frazer

  26. Hepatic Iron Metabolism

    Article • Seminars in Liver Disease, January 2005, Thieme Publishing Group

    Dr David M Frazer

  27. Delayed hepcidin response explains the lag period in iron absorption following a stimulus to increase erythropoiesis

    Article • Gut, October 2004, BMJ

    Dr David M Frazer

  28. Increased duodenal expression of divalent metal transporter 1 and iron-regulated gene 1 in cirrhosis

    Article • Hepatology, January 2004, Wiley

    Dr David M Frazer

  29. The orchestration of body iron intake: how and where do enterocytes receive their cues?

    Article • Blood Cells Molecules and Diseases, May 2003, Elsevier

    Dr David M Frazer

  30. A rapid decrease in the expression of DMT1 and Dcytb but not Ireg1 or hephaestin explains the mucosal block phenomenon of iron absorption

    Article • Gut, March 2003, BMJ

    Dr David M Frazer

  31. Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis

    Article • The Lancet, February 2003, Elsevier

    Dr David M Frazer, Professor Nathan Subramaniam

  32. The Ceruloplasmin Homolog Hephaestin and the Control of Intestinal Iron Absorption

    Article • Blood Cells Molecules and Diseases, November 2002, Elsevier

    Dr David M Frazer

  33. Hepcidin expression inversely correlates with the expression of duodenal iron transporters and iron absorption in rats

    Article • Gastroenterology, September 2002, Elsevier

    Dr David M Frazer

  34. Relationship between intestinal iron-transporter expression, hepatic hepcidin levels and the control of iron absorption

    Article • Biochemical Society Transactions, August 2002, Portland Press Ltd.

    Dr David M Frazer

  35. The Expression and Regulation of the Iron Transport Molecules Hephaestin and IREG1

    Article • Cell Biochemistry and Biophysics, January 2002, Springer Science + Business Media

    Dr David M Frazer

  36. CHANGES IN DUODENAL IRON TRANSPORT GENE EXPRESSION IN RATS FOLLOWING A SWITCH TO AN IRON DEFICIENT DIET OCCUR BEFORE ALTERATIONS IN BODY IRON STORES

    Article • Journal of Gastroenterology and Hepatology, December 2001, Wiley

    Dr David M Frazer

  37. Intestinal iron transporter expression in liver disease

    Article • Gastroenterology, April 2001, Elsevier

    Dr David M Frazer

  38. The relative importance of luminal and systemic signals in the control of intestinal iron absorption

    Article • Gastroenterology, April 2001, Elsevier

    Dr David M Frazer

  39. Intestinal iron transporter expression in liver disease

    Article • Gastroenterology, April 2001, Elsevier

    Dr David M Frazer

  40. The relative importance of luminal and systemic signals in the control of intestinal iron absorption

    Article • Gastroenterology, April 2001, Elsevier

    Dr David M Frazer

  41. Subcellular localization and differentiation-associated expression of hephaestin: A protein required for intestinal iron absorption

    Article • Gastroenterology, April 2000, Elsevier

    Dr David M Frazer

  42. Distribution and regulation of iron transport genes in the rat gastrointestinal tract: Implications for the control of iron absorption

    Article • Gastroenterology, April 2000, Elsevier

    Dr David M Frazer