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  1. Towards next-generation treatment options to combat Plasmodium falciparum malaria

    Article • Nature Reviews Microbiology, October 2024, Springer Science + Business Media

    Professor David A Fidock

  2. Author Correction: Antimalarial drug discovery: progress and approaches

    Article • Nature Reviews Drug Discovery, September 2024, Springer Science + Business Media

    Professor David A Fidock

  3. tRNA modification reprogramming contributes to artemisinin resistance in Plasmodium falciparum

    Article • Nature Microbiology, April 2024, Springer Science + Business Media

    Professor David A Fidock

  4. Drug-induced stress mediates Plasmodium falciparum ring-stage growth arrest and reduces in vitro parasite susceptibility to artemisinin

    Article • Microbiology Spectrum, February 2024, ASM Journals

    Professor David A Fidock

  5. Antimalarial drug discovery: progress and approaches

    Article • Nature Reviews Drug Discovery, August 2023, Springer Science + Business Media

    Professor David A Fidock

  6. Keystone Malaria Symposium 2022: a vibrant discussion of progress made and challenges ahead from drug discovery to treatment

    Article • Trends in Parasitology, July 2022, Elsevier

    Professor David A Fidock

  7. The RTS,S vaccine—a chance to regain the upper hand against malaria?

    Article • Cell, March 2022, Elsevier

    Professor David A Fidock

  8. Comparative Analysis of Plasmodium falciparum Genotyping via SNP Detection, Microsatellite Profiling, and Whole-Genome Sequencing

    Article • Antimicrobial Agents and Chemotherapy, January 2022, ASM Journals

    Professor David A Fidock

  9. The Plasmodium falciparum protein PfMRP1 functions as an influx ABC transporter

    Article • January 2022, Research Square

    Professor David A Fidock

  10. Malaria parasite beats the heat

    Article • Nature Microbiology, August 2021, Springer Science + Business Media

    Professor David A Fidock

  11. Assessing risks of Plasmodium falciparum resistance to select next-generation antimalarials

    Article • Trends in Parasitology, August 2021, Elsevier

    Professor David A Fidock

  12. Hemozoin Promotes Lung Inflammation via Host Epithelial Activation

    Article • mBio, February 2021, ASM Journals

    Professor David A Fidock

  13. Plasmodium berghei K13 Mutations Mediate In Vivo Artemisinin Resistance That Is Reversed by Proteasome Inhibition

    Article • mBio, November 2020, ASM Journals

    Professor David A Fidock

  14. Genetic screens reveal a central role for heme metabolism in artemisinin susceptibility

    Article • Nature Communications, September 2020, Springer Science + Business Media

    Professor David A Fidock

  15. Insights into the intracellular localization, protein associations and artemisinin resistance properties of Plasmodium falciparum K13

    Article • PLoS Pathogens, April 2020, PLOS

    Professor David A Fidock

  16. Turning the tide: targeting PfCRT to combat drug-resistant P. falciparum?

    Article • Nature Reviews Microbiology, April 2020, Springer Science + Business Media

    Professor David A Fidock

  17. Pan-active imidazolopiperazine antimalarials target the Plasmodium falciparum intracellular secretory pathway

    Article • Nature Communications, April 2020, Springer Science + Business Media

    Professor David A Fidock

  18. A phase 1, placebo controlled, randomised, single ascending dose study and a volunteer infection study to characterize the safety, pharmacokinetics and antimalarial activity of the Plasmodium phosphatidylinositol 4-kinase inhibitor MMV390048

    Article • Clinical Infectious Diseases, April 2020, Oxford University Press (OUP)

    Professor David A Fidock

  19. Structure-Based Screening of Plasmodium berghei Glutathione S-Transferase Identifies CB-27 as a Novel Antiplasmodial Compound

    Article • Frontiers in Pharmacology, March 2020, Frontiers

    Professor David A Fidock

  20. Probing the Open Global Health Chemical Diversity Library for Multistage-Active Starting Points for Next-Generation Antimalarials

    Article • ACS Infectious Diseases, February 2020, American Chemical Society (ACS)

    Professor David A Fidock

  21. Preclinical Antimalarial Combination Study of M5717, a Plasmodium falciparum Elongation Factor 2 Inhibitor, and Pyronaridine, a Hemozoin Formation Inhibitor

    Article • Antimicrobial Agents and Chemotherapy, February 2020, ASM Journals

    Professor David A Fidock

  22. The Antimalarial Natural Product Salinipostin A Identifies Essential α/β Serine Hydrolases Involved in Lipid Metabolism in P. falciparum Parasites

    Article • Cell Chemical Biology, February 2020, Elsevier

    Professor David A Fidock

  23. Combining Stage Specificity and Metabolomic Profiling to Advance Antimalarial Drug Discovery

    Article • Cell Chemical Biology, February 2020, Elsevier

    Professor David A Fidock

  24. Structure and drug resistance of the Plasmodium falciparum transporter PfCRT

    Article • Nature, November 2019, Springer Science + Business Media

    Professor David A Fidock

  25. Plasmodium falciparum resistance to piperaquine driven by PfCRT

    Article • The Lancet Infectious Diseases, November 2019, Elsevier

    Professor David A Fidock, Prof Didier Menard

  26. Blocking Plasmodium Development in Mosquitoes: A Powerful New Approach for Expanding Malaria Control Efforts

    Article • American Journal of Tropical Medicine and Hygiene, October 2019, American Society of Tropical Medicine and Hygiene

    Professor David A Fidock

  27. Generation of Transmission-Competent Human Malaria Parasites with Chromosomally-Integrated Fluorescent Reporters

    Article • Scientific Reports, September 2019, Springer Science + Business Media

    Professor David A Fidock

  28. Accelerated evolution and spread of multidrug-resistant Plasmodium falciparum takes down the latest first-line antimalarial drug in southeast Asia

    Article • The Lancet Infectious Diseases, September 2019, Elsevier

    Professor David A Fidock, Prof Didier Menard

  29. Elucidating Mechanisms of Drug-Resistant Plasmodium falciparum

    Article • Cell Host & Microbe, July 2019, Elsevier

    Professor David A Fidock

  30. Structure-Guided Identification of Resistance Breaking Antimalarial N‑Myristoyltransferase Inhibitors

    Article • Cell Chemical Biology, July 2019, Elsevier

    Professor David A Fidock

  31. Pyronaridine-artesunate Shows Promise as an Effective and Well-tolerated Treatment for Artemisinin-resistant Plasmodium falciparum Malaria

    Article • Clinical Infectious Diseases, June 2019, Oxford University Press (OUP)

    Professor David A Fidock

  32. Covalent Plasmodium falciparum-selective proteasome inhibitors exhibit a low propensity for generating resistance in vitro and synergize with multiple antimalarial agents

    Article • PLoS Pathogens, June 2019, PLOS

    Professor David A Fidock

  33. Cyclization-blocked proguanil as a strategy to improve the antimalarial activity of atovaquone

    Article • Communications Biology, May 2019, Springer Science + Business Media

    Professor David A Fidock

  34. Global Spread of Mutant PfCRT and Its Pleiotropic Impact on Plasmodium falciparum Multidrug Resistance and Fitness

    Article • mBio, April 2019, ASM Journals

    Professor David A Fidock

  35. Comparative 3D genome organization in apicomplexan parasites

    Article • Proceedings of the National Academy of Sciences, February 2019, Proceedings of the National Academy of Sciences

    Professor David A Fidock

  36. Plasmodium falciparum In Vitro Drug Resistance Selections and Gene Editing

    Article • January 2019, Springer Science + Business Media

    Professor David A Fidock

  37. Open-source discovery of chemical leads for next-generation chemoprotective antimalarials

    Article • Science, December 2018, American Association for the Advancement of Science

    Professor David A Fidock

  38. Artemisinin resistance phenotypes and K13 inheritance in a Plasmodium falciparum cross and Aotus model

    Article • Proceedings of the National Academy of Sciences, November 2018, Proceedings of the National Academy of Sciences

    Professor David A Fidock

  39. Identification and Mechanistic Understanding of Dihydroorotate Dehydrogenase Point Mutations in Plasmodium falciparum that Confer in Vitro Resistance to the Clinical Candidate DSM265

    Article • ACS Infectious Diseases, October 2018, American Chemical Society (ACS)

    Professor David A Fidock, Professor Diana R. Tomchick

  40. Erratum for Brunschwig et al., “UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria”

    Article • Antimicrobial Agents and Chemotherapy, October 2018, ASM Journals

    Professor David A Fidock

  41. Evidence for Regulation of Hemoglobin Metabolism and Intracellular Ionic Flux by the Plasmodium falciparum Chloroquine Resistance Transporter

    Article • Scientific Reports, September 2018, Springer Science + Business Media

    Professor David A Fidock

  42. Stable Integration and Comparison of hGrx1-roGFP2 and sfroGFP2 Redox Probes in the Malaria Parasite Plasmodium falciparum

    Article • ACS Infectious Diseases, August 2018, American Chemical Society (ACS)

    Professor David A Fidock

  43. Emerging Southeast Asian PfCRT mutations confer Plasmodium falciparum resistance to the first-line antimalarial piperaquine

    Article • Nature Communications, August 2018, Springer Science + Business Media

    Professor David A Fidock, Prof Didier Menard

  44. Defining the Determinants of Specificity of Plasmodium Proteasome Inhibitors

    Article • Journal of the American Chemical Society, August 2018, American Chemical Society (ACS)

    Professor David A Fidock

  45. Antimalarial activity of single-dose DSM265, a novel plasmodium dihydroorotate dehydrogenase inhibitor, in patients with uncomplicated Plasmodium falciparum or Plasmodium vivax malaria infection: a proof-of-concept, open-label, phase 2a study

    Article • The Lancet Infectious Diseases, August 2018, Elsevier

    Professor David A Fidock

  46. UCT943, a Next-GenerationPlasmodium falciparumPI4K Inhibitor Preclinical Candidate for the Treatment of Malaria

    Article • Antimicrobial Agents and Chemotherapy, June 2018, ASM Journals

    Professor David A Fidock

  47. Changes in genome organization of parasite-specific gene families during the Plasmodium transmission stages

    Article • Nature Communications, May 2018, Springer Science + Business Media

    Professor David A Fidock

  48. A Breathprint for Malaria: New Opportunities for Noninterventional Diagnostics and Mosquito Traps?

    Article • The Journal of Infectious Diseases, February 2018, Oxford University Press (OUP)

    Professor David A Fidock

  49. Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics

    Article • Science, January 2018, American Association for the Advancement of Science

    Professor David A Fidock

  50. Hydrogen peroxide dynamics in subcellular compartments of malaria parasites using genetically encoded redox probes

    Article • Scientific Reports, September 2017, Springer Science + Business Media

    Professor David A Fidock

  51. Protein Degradation Systems as Antimalarial Therapeutic Targets

    Article • Trends in Parasitology, September 2017, Elsevier

    Professor David A Fidock

  52. Hexahydroquinolines are antimalarial candidates with potent blood-stage and transmission-blocking activity

    Article • Nature Microbiology, August 2017, Springer Science + Business Media

    Professor David A Fidock

  53. Antimalarial drug resistance: linking Plasmodium falciparum parasite biology to the clinic

    Article • Nature Reports Stem Cells, August 2017, Springer Science + Business Media

    Professor David A Fidock

  54. Association of a Novel Mutation in the Plasmodium falciparum Chloroquine Resistance Transporter With Decreased Piperaquine Sensitivity

    Article • The Journal of Infectious Diseases, July 2017, Oxford University Press (OUP)

    Professor David A Fidock

  55. Safety, tolerability, pharmacokinetics, and activity of the novel long-acting antimalarial DSM265: a two-part first-in-human phase 1a/1b randomised study

    Article • The Lancet Infectious Diseases, June 2017, Elsevier

    Professor David A Fidock

  56. A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance

    Article • Nature Communications, May 2017, Springer Science + Business Media

    Professor David A Fidock

  57. The Plasmodium PI(4)K inhibitor KDU691 selectively inhibits dihydroartemisinin-pretreated Plasmodium falciparum ring-stage parasites

    Article • Scientific Reports, May 2017, Springer Science + Business Media

    Professor David A Fidock

  58. A Variant PfCRT Isoform Can Contribute to Plasmodium falciparum Resistance to the First-Line Partner Drug Piperaquine

    Article • mBio, May 2017, ASM Journals

    Professor David A Fidock

  59. Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase

    Article • Science Translational Medicine, April 2017, American Association for the Advancement of Science

    Professor David A Fidock

  60. Plasmodium falciparum K13 Mutations Differentially Impact Ozonide Susceptibility and Parasite Fitness In Vitro

    Article • mBio, April 2017, ASM Journals

    Professor David A Fidock

  61. A potent antimalarial benzoxaborole targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue

    Article • Nature Communications, March 2017, Springer Science + Business Media

    Professor David A Fidock

  62. A high susceptibility to redox imbalance of the transmissible stages of Plasmodium falciparum revealed with a luciferase‐based mature gametocyte assay

    Article • Molecular Microbiology, February 2017, Wiley

    Elisabeth Davioud-Charvet, Professor David A Fidock

  63. A surrogate marker of piperaquine-resistant Plasmodium falciparum malaria: a phenotype–genotype association study

    Article • The Lancet Infectious Diseases, February 2017, Elsevier

    Prof Didier Menard, Professor David A Fidock

  64. Evolution of Fitness Cost-Neutral Mutant PfCRT Conferring P. falciparum 4-Aminoquinoline Drug Resistance Is Accompanied by Altered Parasite Metabolism and Digestive Vacuole Physiology

    Article • PLoS Pathogens, November 2016, PLOS

    Professor David A Fidock

  65. Drug discovery: Chemical diversity targets malaria

    Article • Nature, October 2016, Nature

    Professor David A Fidock

  66. Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose–Efficacy Modeling

    Article • PLoS Medicine, October 2016, PLOS

    Professor David A Fidock

  67. UDP-galactose and acetyl-CoA transporters as Plasmodium multidrug resistance genes

    Article • Nature Microbiology, September 2016, Springer Science + Business Media

    Professor David A Fidock

  68. Artemisinin Action and Resistance in Plasmodium falciparum

    Article • Trends in Parasitology, September 2016, Elsevier

    Professor David A Fidock

  69. Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

    Article • PLoS Pathogens, July 2016, PLOS

    Dr. Mohamed Abdo Rizk, Professor David A Fidock

  70. A Worldwide Map ofPlasmodium falciparumK13-Propeller Polymorphisms

    Article • New England Journal of Medicine, June 2016, New England Journal of Medicine (NEJM/MMS)

    Prof Didier Menard, Professor David A Fidock

  71. A broad analysis of resistance development in the malaria parasite

    Article • Nature Communications, June 2016, Springer Science + Business Media

    Professor David A Fidock

  72. Globally prevalent PfMDR1 mutations modulate Plasmodium falciparum susceptibility to artemisinin-based combination therapies

    Article • Nature Communications, May 2016, Springer Science + Business Media

    Professor David A Fidock

  73. CRISPR-Cas9-modifiedpfmdr1protectsPlasmodium falciparumasexual blood stages and gametocytes against a class of piperazine-containing compounds but potentiates artemisinin-based combination therapy partner drugs

    Article • Molecular Microbiology, May 2016, Wiley

    Professor David A Fidock

  74. Evidence of a Mild Mutator Phenotype in Cambodian Plasmodium falciparum Malaria Parasites

    Article • PLoS ONE, April 2016, PLOS

    Professor David A Fidock

  75. Substrate and Inhibitor Specificity of the Plasmodium berghei Equilibrative Nucleoside Transporter Type 1

    Article • Molecular Pharmacology, April 2016, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor David A Fidock

  76. Unraveling the Genetic Puzzle of Malaria Drug Resistance

    Article • Molecular Biology and Evolution, February 2016, Oxford University Press (OUP)

    Professor David A Fidock, Assoc. Prof. Charin Modchang

  77. Luciferase-Based, High-Throughput Assay for Screening and Profiling Transmission-Blocking Compounds against Plasmodium falciparum Gametocytes

    Article • Antimicrobial Agents and Chemotherapy, January 2016, ASM Journals

    Professor David A Fidock

  78. Genome-wide transcriptome profiling reveals functional networks involving the Plasmodium falciparum drug resistance transporters PfCRT and PfMDR1

    Article • BMC Genomics, December 2015, Springer Science + Business Media

    Professor David A Fidock

  79. Correction for Jiménez-Díaz et al., (+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium

    Article • Proceedings of the National Academy of Sciences, October 2015, Proceedings of the National Academy of Sciences

    Professor David A Fidock

  80. Mutations in the Plasmodium falciparum chloroquine resistance transporter, PfCRT, enlarge the parasite’s food vacuole and alter drug sensitivities

    Article • Scientific Reports, September 2015, Springer Science + Business Media

    Professor David A Fidock

  81. Profiling the Essential Nature of Lipid Metabolism in Asexual Blood and Gametocyte Stages of Plasmodium falciparum

    Article • Cell Host & Microbe, September 2015, Elsevier

    Professor David A Fidock

  82. Adaptive evolution of malaria parasites in French Guiana: Reversal of chloroquine resistance by acquisition of a mutation in pfcrt

    Article • Proceedings of the National Academy of Sciences, August 2015, Proceedings of the National Academy of Sciences

    Professor David A Fidock

  83. A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria

    Article • Science Translational Medicine, July 2015, American Association for the Advancement of Science

    Professor David A Fidock, Professor Diana R. Tomchick

  84. Parasite-induced ER stress response in hepatocytes facilitates Plasmodium liver stage infection

    Article • EMBO Reports, June 2015, EMBO

    Professor David A Fidock

  85. A novel multiple-stage antimalarial agent that inhibits protein synthesis

    Article • Nature, June 2015, Springer Science + Business Media

    Professor David A Fidock

  86. Balancing drug resistance and growth rates via compensatory mutations in thePlasmodium falciparumchloroquine resistance transporter

    Article • Molecular Microbiology, May 2015, Wiley

    Professor David A Fidock

  87. Targeting the Cell Stress Response of Plasmodium falciparum to Overcome Artemisinin Resistance

    Article • PLoS Biology, April 2015, PLOS

    Professor David A Fidock

  88. Triaminopyrimidine is a fast-killing and long-acting antimalarial clinical candidate

    Article • Nature Communications, March 2015, Springer Science + Business Media

    Professor David A Fidock

  89. The Mu Subunit of Plasmodium falciparum Clathrin-Associated Adaptor Protein 2 ModulatesIn VitroParasite Response to Artemisinin and Quinine

    Article • Antimicrobial Agents and Chemotherapy, February 2015, ASM Journals

    Professor David A Fidock

  90. Yeast-Based High-Throughput Screen Identifies Plasmodium falciparum Equilibrative Nucleoside Transporter 1 Inhibitors That Kill Malaria Parasites

    Article • ACS Chemical Biology, January 2015, American Chemical Society (ACS)

    Professor David A Fidock

  91. Subtle Changes in Endochin-Like Quinolone Structure Alter the Site of Inhibition within the Cytochromebc1Complex of Plasmodium falciparum

    Article • Antimicrobial Agents and Chemotherapy, January 2015, ASM Journals

    Michael Riscoe, Professor David A Fidock

  92. K13-propeller mutations confer artemisinin resistance in Plasmodium falciparum clinical isolates

    Article • Science, December 2014, American Association for the Advancement of Science

    Prof Didier Menard, Professor David A Fidock

  93. (+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium

    Article • Proceedings of the National Academy of Sciences, December 2014, Proceedings of the National Academy of Sciences

    Dr Natalie J. Spillman, Professor David A Fidock

  94. DNA Repair Mechanisms and Their Biological Roles in the Malaria Parasite Plasmodium falciparum

    Article • Microbiology and Molecular Biology Reviews, September 2014, ASM Journals

    Professor David A Fidock

  95. Multicolor Bioluminescence Boosts Malaria Research: Quantitative Dual-Color Assay and Single-Cell Imaging in Plasmodium falciparum Parasites

    Article • Analytical Chemistry, August 2014, American Chemical Society (ACS)

    Professor David A Fidock

  96. N -Aryl-2-aminobenzimidazoles: Novel, Efficacious, Antimalarial Lead Compounds

    Article • Journal of Medicinal Chemistry, August 2014, American Chemical Society (ACS)

    Professor David A Fidock

  97. CRISPR-mediated genome editing of Plasmodium falciparum malaria parasites

    Article • Genome Medicine, August 2014, Springer Science + Business Media

    Professor David A Fidock

  98. Supergenomic Network Compression and the Discovery of EXP1 as a Glutathione Transferase Inhibited by Artesunate

    Article • Cell, August 2014, Elsevier

    Professor David A Fidock

  99. Editing thePlasmodium vivaxGenome, Using Zinc-Finger Nucleases

    Article • The Journal of Infectious Diseases, July 2014, Oxford University Press (OUP)

    Professor David A Fidock

  100. KAF156 Is an Antimalarial Clinical Candidate with Potential for Use in Prophylaxis, Treatment, and Prevention of Disease Transmission

    Article • Antimicrobial Agents and Chemotherapy, June 2014, ASM Journals

    Professor David A Fidock

  101. Transfusion of stored blood impairs host defenses against Gram‐negative pathogens in mice

    Article • Transfusion, May 2014, Wiley

    Professor David A Fidock, Dr Steven L Spitalnik, Prof Michael R Hamblin

  102. Mechanisms of Antimalarial Drug Action and Resistance

    Article • April 2014, ASM Journals

    Professor David A Fidock

  103. Origin of Robustness in Generating Drug-Resistant Malaria Parasites

    Article • Molecular Biology and Evolution, April 2014, Oxford University Press (OUP)

    Professor David A Fidock, Assoc. Prof. Charin Modchang

  104. Modeling Within-Host Effects of Drugs on Plasmodium falciparum Transmission and Prospects for Malaria Elimination

    Article • PLoS Computational Biology, January 2014, PLOS

    Professor David A Fidock

  105. Quinine Dimers Are Potent Inhibitors of the Plasmodium falciparum Chloroquine Resistance Transporter and Are Active against Quinoline-Resistant P. falciparum

    Article • ACS Chemical Biology, January 2014, American Chemical Society (ACS)

    Professor David A Fidock

  106. Discrimination of Potent Inhibitors ofToxoplasma gondiiEnoyl-Acyl Carrier Protein Reductase by a Thermal Shift Assay

    Article • Biochemistry, December 2013, American Chemical Society (ACS)

    Professor David A Fidock

  107. Characterization of the ATG8-conjugation system in 2Plasmodiumspecies with special focus on the liver stage

    Article • Autophagy, December 2013, Taylor & Francis

    Professor David A Fidock

  108. Type II Fatty Acid Biosynthesis Is Essential for Plasmodium falciparum Sporozoite Development in the Midgut of Anopheles Mosquitoes

    Article • Eukaryotic Cell, December 2013, ASM Journals

    Professor David A Fidock

  109. Targeting Plasmodium PI(4)K to eliminate malaria

    Article • Nature, November 2013, Springer Science + Business Media

    Professor David A Fidock

  110. Evidence for Pyronaridine as a Highly Effective Partner Drug for Treatment of Artemisinin-Resistant Malaria in a Rodent Model

    Article • Antimicrobial Agents and Chemotherapy, October 2013, ASM Journals

    Professor David A Fidock

  111. Plasmodium falciparum phosphoethanolamine methyltransferase is essential for malaria transmission

    Article • Proceedings of the National Academy of Sciences, October 2013, Proceedings of the National Academy of Sciences

    Professor David A Fidock

  112. Identification of MMV Malaria Box Inhibitors of Plasmodium falciparum Early-Stage Gametocytes Using a Luciferase-Based High-Throughput Assay

    Article • Antimicrobial Agents and Chemotherapy, September 2013, ASM Journals

    Professor David A Fidock

  113. Using Genetic Methods To Define the Targets of Compounds with Antimalarial Activity

    Article • Journal of Medicinal Chemistry, September 2013, American Chemical Society (ACS)

    Professor David A Fidock

  114. Eliminating Malaria

    Article • Science, June 2013, American Association for the Advancement of Science

    Professor David A Fidock

  115. UV-triggered Affinity Capture Identifies Interactions between thePlasmodium falciparumMultidrug Resistance Protein 1 (PfMDR1) and Antimalarial Agents in Live Parasitized Cells

    Article • Journal of Biological Chemistry, June 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor David A Fidock

  116. Malaria's Missing Number: Calculating the Human Component of R0 by a Within-Host Mechanistic Model of Plasmodium falciparum Infection and Transmission

    Article • PLoS Computational Biology, April 2013, PLOS

    Professor David A Fidock

  117. A key role for lipoic acid synthesis duringPlasmodiumliver stage development

    Article • Cellular Microbiology, April 2013, Hindawi Publishing Corporation

    Professor David A Fidock

  118. Spatial and temporal mapping of the PfEMP1 export pathway inPlasmodium falciparum

    Article • Cellular Microbiology, March 2013, Wiley

    Professor David A Fidock

  119. Mitotic Evolution of Plasmodium falciparum Shows a Stable Core Genome but Recombination in Antigen Families

    Article • PLoS Genetics, February 2013, PLOS

    Professor David A Fidock

  120. Novel diaryl ureas with efficacy in a mouse model of malaria

    Article • Bioorganic & Medicinal Chemistry Letters, February 2013, Elsevier

    Dr Sean Ekins, Joel Freundlich, Professor David A Fidock

  121. An integrated strategy for efficient vector construction and multi-gene expression in Plasmodium falciparum

    Article • Malaria Journal, January 2013, Springer Science + Business Media

    Professor David A Fidock

  122. Degrees of chloroquine resistance in Plasmodium – Is the redox system involved?

    Article • International Journal for Parasitology Drugs and Drug Resistance, December 2012, Elsevier

    Professor David A Fidock

  123. PfCRT and its role in antimalarial drug resistance

    Article • Trends in Parasitology, November 2012, Elsevier

    Professor David A Fidock

  124. Tricks in Plasmodium’s molecular repertoire – Escaping 3′UTR excision-based conditional silencing of the chloroquine resistance transporter gene

    Article • International Journal for Parasitology, October 2012, Elsevier

    Professor David A Fidock

  125. Site-specific genome editing in Plasmodium falciparum using engineered zinc-finger nucleases

    Article • Nature Methods, August 2012, Nature

    Professor David A Fidock

  126. No Evidence of Decreased Artemisinin Efficacy in a High-Transmission Malaria Setting in Mali

    Article • American Journal of Tropical Medicine and Hygiene, July 2012, American Society of Tropical Medicine and Hygiene

    Professor David A Fidock

  127. Loss of malarial susceptibility to artemisinin in Thailand

    Article • The Lancet, May 2012, Elsevier

    Professor David A Fidock

  128. Perspectives: The missing pieces

    Article • Nature, April 2012, Springer Science + Business Media

    Professor David A Fidock

  129. Diversity-Oriented Synthesis Yields a Novel Lead for the Treatment of Malaria

    Article • ACS Medicinal Chemistry Letters, December 2011, American Chemical Society (ACS)

    Professor David A Fidock

  130. Recent clinical and molecular insights into emerging artemisinin resistance in Plasmodium falciparum

    Article • Current Opinion in Infectious Diseases, December 2011, Wolters Kluwer Health

    Professor David A Fidock

  131. Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery

    Article • Science, November 2011, American Association for the Advancement of Science

    Professor David A Fidock

  132. In VitroandIn VivoActivity of Solithromycin (CEM-101) against Plasmodium Species

    Article • Antimicrobial Agents and Chemotherapy, November 2011, ASM Journals

    Professor David A Fidock

  133. Quantitative assessment of Plasmodium falciparum sexual development reveals potent transmission-blocking activity by methylene blue

    Article • Proceedings of the National Academy of Sciences, October 2011, Proceedings of the National Academy of Sciences

    Professor David A Fidock

  134. In vitro and in vivo activity of frenolicin B against Plasmodium falciparum and P berghei

    Article • The Journal of Antibiotics, October 2011, Springer Science + Business Media

    Professor David A Fidock

  135. Chemical Genomic Profiling for Antimalarial Therapies, Response Signatures, and Molecular Targets

    Article • Science, August 2011, American Association for the Advancement of Science

    Professor David A Fidock

  136. Identifying apicoplast‐targeting antimalarials using high‐throughput compatible approaches

    Article • The FASEB Journal, July 2011, Wiley

    Professor David A Fidock

  137. Piperaquine Resistance Is Associated with a Copy Number Variation on Chromosome 5 in Drug-PressuredPlasmodium falciparumParasites

    Article • Antimicrobial Agents and Chemotherapy, May 2011, ASM Journals

    Professor David A Fidock

  138. Taking Charge: Feeding Malaria via Anion Channels

    Article • Cell, May 2011, Elsevier

    Professor David A Fidock

  139. In VivoandIn VitroAntimalarial Properties of Azithromycin-Chloroquine Combinations That Include the Resistance Reversal Agent Amlodipine

    Article • Antimicrobial Agents and Chemotherapy, April 2011, ASM Journals

    Professor David A Fidock

  140. Differential Drug Efflux or Accumulation Does Not Explain Variation in the Chloroquine Response of Plasmodium falciparum Strains Expressing the Same Isoform of Mutant PfCRT

    Article • Antimicrobial Agents and Chemotherapy, February 2011, ASM Journals

    Professor David A Fidock

  141. Evidence That Mutant PfCRT Facilitates the Transmission to Mosquitoes of Chloroquine-Treated Plasmodium Gametocytes

    Article • The Journal of Infectious Diseases, January 2011, Oxford University Press (OUP)

    Professor David A Fidock

  142. Triclosan is minimally effective in rodent malaria models

    Article • Nature Reports Stem Cells, January 2011, Springer Science + Business Media

    Professor Alan H Fairlamb, Professor David A Fidock

  143. Molecular Markers of Plasmodium Resistance to Antimalarials

    Article • January 2011, Springer Science + Business Media

    Professor David A Fidock

  144. How can we identify parasite genes that underlie antimalarial drug resistance?

    Article • Pharmacogenomics, January 2011, Future Medicine

    Professor David A Fidock

  145. Spiroindolones, a Potent Compound Class for the Treatment of Malaria

    Article • Science, September 2010, American Association for the Advancement of Science

    Professor David A Fidock

  146. Investigations into the Role of the Plasmodium falciparum SERCA (PfATP6) L263E Mutation in Artemisinin Action and Resistance

    Article • Antimicrobial Agents and Chemotherapy, June 2010, ASM Journals

    Professor David A Fidock

  147. Identification of a Mutant PfCRT-Mediated Chloroquine Tolerance Phenotype in Plasmodium falciparum

    Article • PLoS Pathogens, May 2010, PLOS

    Professor David A Fidock

  148. Priming the antimalarial pipeline

    Article • Nature, May 2010, Springer Science + Business Media

    Professor David A Fidock

  149. Identification of a role for the PfEMP1 semi-conserved head structure in protein trafficking to the surface of Plasmodium falciparum infected red blood cells

    Article • Cellular Microbiology, April 2010, Hindawi Publishing Corporation

    Professor David A Fidock

  150. Recent insights into fatty acid acquisition and metabolism in malarial parasites

    Article • F1000 Biology Reports, March 2010, F1000Research

    Professor David A Fidock

  151. A Method for Rapid Genetic Integration into Plasmodium falciparum Utilizing Mycobacteriophage Bxb1 Integrase

    Article • January 2010, Springer Science + Business Media

    Professor David A Fidock

  152. Artemisinin-based combination therapies: a vital tool in efforts to eliminate malaria

    Article • Nature Reviews Microbiology, November 2009, Springer Science + Business Media

    Professor David A Fidock

  153. A var gene promoter implicated in severe malaria nucleates silencing and is regulated by 3′ untranslated region and intronic cis-elements

    Article • International Journal for Parasitology, November 2009, Elsevier

    Professor David A Fidock

  154. Role of Plasmodium falciparum Digestive Vacuole Plasmepsins in the Specificity and Antimalarial Mode of Action of Cysteine and Aspartic Protease Inhibitors

    Article • Antimicrobial Agents and Chemotherapy, September 2009, ASM Journals

    Professor David A Fidock

  155. Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum

    Article • Nature Chemical Biology, September 2009, Springer Science + Business Media

    Professor David A Fidock

  156. Oleic Acid Biosynthesis in Plasmodium falciparum: Characterization of the Stearoyl-CoA Desaturase and Investigation as a Potential Therapeutic Target

    Article • PLoS ONE, September 2009, PLOS

    Professor David A Fidock

  157. The Longin Domain Regulates the Steady-State Dynamics of Sec22 in Plasmodium falciparum

    Article • Eukaryotic Cell, July 2009, ASM Journals

    Professor David A Fidock, Dr Theodore F Taraschi

  158. Probing the multifactorial basis of Plasmodium falciparum quinine resistance: Evidence for a strain-specific contribution of the sodium-proton exchanger PfNHE

    Article • Molecular and Biochemical Parasitology, June 2009, Elsevier

    Professor David A Fidock

  159. In Vivo Selection ofPlasmodium falciparumParasites Carrying the Chloroquine-SusceptiblepfcrtK76 Allele after Treatment with Artemether-Lumefantrine in Africa

    Article • The Journal of Infectious Diseases, March 2009, Oxford University Press (OUP)

    Professor David A Fidock

  160. Select pyrimidinones inhibit the propagation of the malarial parasite, Plasmodium falciparum

    Article • Bioorganic & Medicinal Chemistry, February 2009, Elsevier

    Professor David A Fidock

  161. Chemical genomics identifies compounds affecting Xenopus laevis pigment cell development

    Article • Molecular BioSystems, January 2009, Royal Society of Chemistry

    Professor David A Fidock

  162. Use of high-density tiling microarrays to identify mutations globally and elucidate mechanisms of drug resistance in Plasmodium falciparum

    Article • Genome Biology, January 2009, Springer Science + Business Media

    Professor David A Fidock

  163. Recent highlights in antimalarial drug resistance and chemotherapy research

    Article • Trends in Parasitology, December 2008, Elsevier

    Professor David A Fidock

  164. The Fatty Acid Biosynthesis Enzyme FabI Plays a Key Role in the Development of Liver-Stage Malarial Parasites

    Article • Cell Host & Microbe, December 2008, Elsevier

    Professor David A Fidock

  165. In vitro evaluations of antimalarial drugs and their relevance to clinical outcomes

    Article • International Journal for Parasitology, June 2008, Elsevier

    Professor David A Fidock

  166. Plasmodium falciparum Sec24 marks transitional ER that exports a model cargo via a diacidic motif

    Article • Molecular Microbiology, April 2008, Wiley

    Professor David A Fidock

  167. Malaria: progress, perils, and prospects for eradication

    Article • Journal of Clinical Investigation, April 2008, American Society for Clinical Investigation

    Professor David A Fidock

  168. Arresting malaria parasite egress from infected red blood cells

    Article • Nature Chemical Biology, March 2008, Springer Science + Business Media

    Professor David A Fidock

  169. Characterization of a PRL protein tyrosine phosphatase from Plasmodium falciparum☆

    Article • Molecular and Biochemical Parasitology, March 2008, Elsevier

    Professor David A Fidock

  170. Advances in understanding the genetic basis of antimalarial drug resistance

    Article • Current Opinion in Microbiology, August 2007, Elsevier

    Professor David A Fidock

  171. Discovery of novel inhibitors targeting enoyl–acyl carrier protein reductase in Plasmodium falciparum by structure-based virtual screening

    Article • Biochemical and Biophysical Research Communications, July 2007, Elsevier

    Professor David A Fidock

  172. Gene encoding a deubiquitinating enzyme is mutated in artesunate- and chloroquine-resistant rodent malaria parasites

    Article • Molecular Microbiology, July 2007, Wiley

    Professor David A Fidock

  173. X-ray Structural Analysis ofPlasmodium falciparumEnoyl Acyl Carrier Protein Reductase as a Pathway toward the Optimization of Triclosan Antimalarial Efficacy

    Article • Journal of Biological Chemistry, June 2007, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor David A Fidock

  174. Differences in trans-stimulated chloroquine efflux kinetics are linked to PfCRT in Plasmodium falciparum

    Article • Molecular Microbiology, April 2007, Wiley

    Professor David A Fidock

  175. Effects on growth, hemoglobin metabolism and paralogous gene expression resulting from disruption of genes encoding the digestive vacuole plasmepsins of Plasmodium falciparum

    Article • International Journal for Parasitology, March 2007, Elsevier

    Professor David A Fidock

  176. Chloroquine-resistant isoforms of the Plasmodium falciparum chloroquine resistance transporter acidify lysosomal pH in HEK293 cells more than chloroquine-sensitive isoforms

    Article • Molecular and Biochemical Parasitology, December 2006, Elsevier

    Paul Roepe, Professor David A Fidock

  177. In Vitro Efficacy, Resistance Selection, and Structural Modeling Studies Implicate the Malarial Parasite Apicoplast as the Target of Azithromycin

    Article • Journal of Biological Chemistry, November 2006, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor David A Fidock

  178. Transporters involved in resistance to antimalarial drugs

    Article • Trends in Pharmacological Sciences, November 2006, Elsevier

    Professor David A Fidock

  179. PfCRT and the trans-vacuolar proton electrochemical gradient: regulating the access of chloroquine to ferriprotoporphyrin IX

    Article • Molecular Microbiology, October 2006, Wiley

    Professor David A Fidock

  180. First evidence of pfcrt mutant Plasmodium falciparum in Madagascar

    Article • Transactions of the Royal Society of Tropical Medicine and Hygiene, September 2006, Oxford University Press (OUP)

    Professor David A Fidock

  181. Erratum: Efficient site-specific integration in Plasmodium falciparum chromosomes mediated by mycobacteriophage Bxb1 integrase

    Article • Nature Methods, September 2006, Nature

    Professor David A Fidock

  182. Decreasing pfmdr1 Copy Number in Plasmodium falciparum Malaria Heightens Susceptibility to Mefloquine, Lumefantrine, Halofantrine, Quinine, and Artemisinin

    Article • The Journal of Infectious Diseases, August 2006, Oxford University Press (OUP)

    Professor David A Fidock

  183. A ubiquitous Plasmodium protein displays a unique surface labeling pattern in sporozoites☆

    Article • Molecular and Biochemical Parasitology, August 2006, Elsevier

    Professor David A Fidock, Anthony James

  184. Efficient site-specific integration in Plasmodium falciparum chromosomes mediated by mycobacteriophage Bxb1 integrase

    Article • Nature Methods, July 2006, Springer Science + Business Media

    Professor David A Fidock

  185. Erratum to “Synthesis, biological activity, and X-ray crystal structural analysis of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 1: 4′-Substituted triclosan derivatives” [Bioorg. Med. Chem. Lett. 15 (2005) 5247–5252]

    Article • Bioorganic & Medicinal Chemistry Letters, July 2006, Elsevier

    Professor David A Fidock

  186. Genetic linkage of pfmdr1 with food vacuolar solute import in Plasmodium falciparum

    Article • The EMBO Journal, June 2006, Wiley

    Professor David A Fidock

  187. Synthesis and biological activity of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 2: 2′-Substituted triclosan derivatives

    Article • Bioorganic & Medicinal Chemistry Letters, April 2006, Elsevier

    Professor David A Fidock

  188. Correction

    Article • Proceedings of the National Academy of Sciences, December 2005, Proceedings of the National Academy of Sciences

    Professor David A Fidock

  189. Synthesis, biological activity, and X-ray crystal structural analysis of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 1: 4′-Substituted triclosan derivatives

    Article • Bioorganic & Medicinal Chemistry Letters, December 2005, Elsevier

    Professor David A Fidock

  190. Disruption of a Plasmodium falciparum gene linked to male sexual development causes early arrest in gametocytogenesis

    Article • Proceedings of the National Academy of Sciences, November 2005, Proceedings of the National Academy of Sciences

    Professor David A Fidock

  191. Mutations Conferring Drug Resistance in Malaria Parasite Drug Transporters Pgh1 and PfCRT Do Not Affect Steady-State Vacuolar Ca2+

    Article • Antimicrobial Agents and Chemotherapy, November 2005, ASM Journals

    Professor David A Fidock

  192. Crystal structure analysis of plasmodium falciparum enoyl-acyl-carrier-protein reductase with nadh

    Article • July 2005, Protein Data Bank, Rutgers University

    Professor David A Fidock

  193. pfmdr1 mutations contribute to quinine resistance and enhance mefloquine and artemisinin sensitivity in Plasmodium falciparum

    Article • Molecular Microbiology, June 2005, Wiley

    Professor David A Fidock

  194. Evidence for apfcrt-Associated Chloroquine Efflux System in the Human Malarial ParasitePlasmodium falciparum

    Article • Biochemistry, June 2005, American Chemical Society (ACS)

    Professor David A Fidock

  195. A critical role for PfCRT K76T in Plasmodium falciparum verapamil-reversible chloroquine resistance

    Article • The EMBO Journal, June 2005, Wiley

    Professor David A Fidock

  196. Defining the role of PfCRT in Plasmodium falciparum chloroquine resistance

    Article • Molecular Microbiology, March 2005, Wiley

    Professor David A Fidock

  197. Genetic Disruption of the Plasmodium falciparum Digestive Vacuole Plasmepsins Demonstrates Their Functional Redundancy

    Article • Journal of Biological Chemistry, October 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor David A Fidock

  198. Evidence for a Central Role for PfCRT in Conferring Plasmodium falciparum Resistance to Diverse Antimalarial Agents

    Article • Molecular Cell, September 2004, Elsevier

    Professor David A Fidock

  199. Drug resistance-associated pfCRT mutations confer decreased Plasmodium falciparum digestive vacuolar pH

    Article • Molecular and Biochemical Parasitology, January 2004, Elsevier

    Professor David A Fidock

  200. Chloroquine Resistance Modulated in Vitro by Expression Levels of the Plasmodium falciparum Chloroquine Resistance Transporter

    Article • Journal of Biological Chemistry, June 2003, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor David A Fidock

  201. Targeting Tuberculosis and Malaria through Inhibition of Enoyl Reductase

    Article • Journal of Biological Chemistry, February 2003, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor David A Fidock

  202. CRYSTAL STRUCTURE ANALYSIS OF PLASMODIUM FALCIPARUM ENOYL-ACYL-CARRIER-PROTEIN REDUCTASE WITH NADH

    Article • February 2003, Protein Data Bank, Rutgers University

    Professor David A Fidock

  203. Chloroquine Resistance inPlasmodium falciparumMalaria Parasites Conferred bypfcrtMutations

    Article • Science, October 2002, American Association for the Advancement of Science

    Professor David A Fidock

  204. Structural Elucidation of the Specificity of the Antibacterial Agent Triclosan for Malarial Enoyl Acyl Carrier Protein Reductase

    Article • Journal of Biological Chemistry, January 2002, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor David A Fidock

  205. Alternative Mutations at Position 76 of the Vacuolar Transmembrane Protein PfCRT Are Associated with Chloroquine Resistance and Unique Stereospecific Quinine and Quinidine Responses inPlasmodium falciparum

    Article • Molecular Pharmacology, January 2002, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor David A Fidock

  206. Evolution of a unique Plasmodium falciparum chloroquine-resistance phenotype in association with pfcrt polymorphism in Papua New Guinea and South America

    Article • Proceedings of the National Academy of Sciences, October 2001, Proceedings of the National Academy of Sciences

    Professor David A Fidock

  207. Conservation of a novel vacuolar transporter in Plasmodium species and its central role in chloroquine resistance of P. falciparum

    Article • Current Opinion in Microbiology, August 2001, Elsevier

    Professor David A Fidock

  208. Disruption of Plasmodium falciparumChitinase Markedly Impairs Parasite Invasion of Mosquito Midgut

    Article • Infection and Immunity, June 2001, ASM Journals

    Professor David A Fidock

  209. Evidence for Different Mechanisms of Chloroquine Resistance in 2PlasmodiumSpecies That Cause Human Malaria

    Article • The Journal of Infectious Diseases, June 2001, Oxford University Press (OUP)

    Professor David A Fidock

  210. Stage-dependent Localization of a Novel Gene Product of the Malaria Parasite,Plasmodium falciparum

    Article • Journal of Biological Chemistry, May 2001, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor David A Fidock, Anthony James

  211. A Molecular Marker for Chloroquine-Resistant Falciparum Malaria

    Article • New England Journal of Medicine, January 2001, New England Journal of Medicine (NEJM/MMS)

    Professor David A Fidock

  212. Mutations in the P. falciparum Digestive Vacuole Transmembrane Protein PfCRT and Evidence for Their Role in Chloroquine Resistance

    Article • Molecular Cell, October 2000, Elsevier

    Paul Roepe, Professor David A Fidock

  213. Disruption of the C-terminal region of EBA-175 in the Dd2/Nm clone of Plasmodium falciparum does not affect erythrocyte invasion

    Article • Molecular and Biochemical Parasitology, September 2000, Elsevier

    Professor David A Fidock

  214. Allelic modifications of the cg2 and cg1 genes do not alter the chloroquine response of drug-resistant Plasmodium falciparum

    Article • Molecular and Biochemical Parasitology, September 2000, Elsevier

    Professor David A Fidock

  215. Plasmodium falciparum: Generation of a cDNA Library Enriched in Sporozoite-Specific Transcripts by Directional Tag Subtractive Hybridization

    Article • Experimental Parasitology, July 2000, Elsevier

    Professor David A Fidock, Anthony James

  216. Developmental arrest of the human malaria parasite Plasmodium falciparum within the mosquito midgut via CTRP gene disruption

    Article • Molecular Microbiology, April 2000, Wiley

    Professor David A Fidock

  217. The selectable marker human dihydrofolate reductase enables sequential genetic manipulation of the Plasmodium berghei genome

    Article • Molecular and Biochemical Parasitology, March 2000, Elsevier

    Professor David A Fidock

  218. The chitinase PfCHT1 from the human malaria parasite Plasmodium falciparum lacks proenzyme and chitin-binding domains and displays unique substrate preferences

    Article • Proceedings of the National Academy of Sciences, November 1999, Proceedings of the National Academy of Sciences

    Professor David A Fidock

  219. The Anopheles Mosquito: Genomics and Transformation

    Article • August 1999, Taylor & Francis

    Professor David A Fidock, Dr Xin-zhuan Su

  220. Genome projects, genetic analysis, and the changing landscape of malaria research

    Article • Current Opinion in Microbiology, August 1999, Elsevier

    Professor David A Fidock

  221. Vesicular ATPase-overexpressing Cells Determine the Distribution of Malaria Parasite Oocysts on the Midguts of Mosquitoes

    Article • Journal of Biological Chemistry, April 1999, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor David A Fidock

  222. A candidate molecule for chloroquine resistance in Plasmodium falciparum malaria

    Article • Parasitology International, August 1998, Elsevier

    Professor David A Fidock

  223. P. falciparum CG2, Linked to Chloroquine Resistance, Does Not Resemble Na+/H+ Exchangers

    Article • Cell, August 1998, Elsevier

    Professor David A Fidock, Dr Xin-zhuan Su

  224. Plasmodium falciparum:Ribosomal P2 Protein Gene Expression Is Independent of the Developmentally Regulated rRNAs

    Article • Experimental Parasitology, May 1998, Elsevier

    Professor David A Fidock, Anthony James

  225. Plasmodium falciparum sporozoite invasion is inhibited by naturally acquired or experimentally induced polyclonal antibodies to the STARP antigen

    Article • European Journal of Immunology, October 1997, Wiley

    Professor David A Fidock

  226. Transformation with human dihydrofolate reductase renders malaria parasites insensitive to WR99210 but does not affect the intrinsic activity of proguanil

    Article • Proceedings of the National Academy of Sciences, September 1997, Proceedings of the National Academy of Sciences

    Professor David A Fidock

  227. Identification of conserved antigenic components for a cytotoxic T lymphocyte-inducing vaccine against malaria

    Article • The Lancet, April 1995, Elsevier

    Professor David A Fidock

  228. Conservation of the Plasmodium falciparum sporozoite surface protein gene, STARP, in field isolates and distinct species of Plasmodium

    Article • Molecular and Biochemical Parasitology, October 1994, Elsevier

    Professor David A Fidock

  229. Cloning and characterization of a novel Plasmodium falciparum sporozoite surface antigen, STARP

    Article • Molecular and Biochemical Parasitology, April 1994, Elsevier

    Professor David A Fidock

  230. Nucleotide sequence of the F41 fimbriae subunit gene inEscherichia coliB41

    Article • Nucleic Acids Research, January 1989, Oxford University Press (OUP)

    Professor David A Fidock

  231. Construction of Plasmodium falciparumλ cDNA Libraries

    Article • Springer Science + Business Media

    Professor David A Fidock

  232. Mechanisms of Quinoline Resistance

    Article • Springer Science + Business Media

    Professor David A Fidock

  233. Production of Stage-Specific Plasmodium falciparum cDNA Libraries Using Subtractive Hybridization

    Article • Springer Science + Business Media

    Professor David A Fidock, Anthony James