All Stories

  1. Shift work disrupts body rhythms, accelerates cognitive decline later in life

    Article • Journal of Neuroinflammation, January 2025, Springer Science + Business Media

    David Earnest

  2. Sex differences in the diathetic effects of shift work schedules on circulating cytokine levels and pathological outcomes of ischemic stroke during middle age

    Article • Neurobiology of Sleep and Circadian Rhythms, November 2022, Elsevier

    David Earnest

  3. Role of Proinflammatory Cytokines in Feedback Modulation of Circadian Clock Gene Rhythms by Saturated Fatty Acids

    Article • Scientific Reports, June 2019, Springer Science + Business Media

    David Earnest

  4. Correction to: inhibition of p38 MAPK activity leads to cell type-specific effects on the molecular circadian clock and time-dependent reduction of glioma cell invasiveness

    Article • BMC Cancer, January 2019, Springer Science + Business Media

    David Earnest

  5. PER2 regulation of mammary gland development

    Article • Development, March 2018, The Company of Biologists

    David Earnest

  6. Altered immune cell clocks may contribute to obesity and diabetes in shift workers

    Article • The FASEB Journal, February 2018, Wiley

    David Earnest

  7. Inhibition of p38 MAPK activity leads to cell type-specific effects on the molecular circadian clock and time-dependent reduction of glioma cell invasiveness

    Article • BMC Cancer, January 2018, Springer Science + Business Media

    David Earnest

  8. Sex Differences in the Impact of Shift Work Schedules on Pathological Outcomes in an Animal Model of Ischemic Stroke

    Article • Endocrinology, July 2016, Endocrine Society

    David Earnest

  9. Role of Inflammatory Signaling in the Differential Effects of Saturated and Poly-unsaturated Fatty Acids on Peripheral Circadian Clocks

    Article • EBioMedicine, May 2016, Elsevier

    David Earnest

  10. MicroRNAs function as cis‐ and trans‐acting modulators of peripheral circadian clocks

    Article • FEBS Letters, June 2014, Wiley

    David Earnest

  11. Myeloid Cell-specific Disruption of Period1 and Period2 Exacerbates Diet-induced Inflammation and Insulin Resistance

    Article • Journal of Biological Chemistry, June 2014, Elsevier

    David Earnest

  12. Role of miR-142-3p in the Post-Transcriptional Regulation of the Clock Gene Bmal1 in the Mouse SCN

    Article • PLOS One, June 2013, PLOS

    David Earnest

  13. Diurnal Rhythms in Neurexins Transcripts and Inhibitory/Excitatory Synapse Scaffold Proteins in the Biological Clock

    Article • PLOS One, May 2012, PLOS

    David Earnest

  14. Cardiac-Specific Mutation of Clock Alters the Quantitative Measurements of Physical Activities without Changing Behavioral Circadian Rhythms

    Article • Journal of Biological Rhythms, September 2011, SAGE Publications

    David Earnest

  15. Expression and Rhythmic Modulation of Circulating MicroRNAs Targeting the Clock Gene Bmal1 in Mice

    Article • PLOS One, July 2011, PLOS

    David Earnest

  16. Mitochondrial Calcium Signaling Mediates Rhythmic Extracellular ATP Accumulation in Suprachiasmatic Nucleus Astrocytes

    Article • Journal of Neuroscience, June 2011, Society for Neuroscience

    David Earnest

  17. Immortalized cell lines for real-time analysis of circadian pacemaker and peripheral oscillator properties

    Article • European Journal of Neuroscience, March 2011, Wiley

    David Earnest

  18. The clock genes period 1 and period 2 mediate diurnal rhythms in dioxin-induced Cyp1A1 expression in the mouse mammary gland and liver

    Article • Toxicology Letters, June 2010, Elsevier

    David Earnest

  19. Circadian rhythms of extracellular ATP accumulation in suprachiasmatic nucleus cells and cultured astrocytes

    Article • European Journal of Neuroscience, August 2009, Wiley

    David Earnest

  20. Effects of neonatal alcohol exposure on vasoactive intestinal polypeptide neurons in the rat suprachiasmatic nucleus

    Article • Alcohol, August 2009, Elsevier

    David Earnest

  21. Disruption of period gene expression alters the inductive effects of dioxin on the AhR signaling pathway in the mouse liver

    Article • Toxicology and Applied Pharmacology, February 2009, Elsevier

    David Earnest

  22. Neonatal Alcohol Exposure Differentially Alters Clock Gene Oscillations Within the Suprachiasmatic Nucleus, Cerebellum, and Liver of Adult Rats

    Article • Alcoholism Clinical and Experimental Research, January 2008, Wiley

    David Earnest

  23. Disruption of Clock Gene Expression Alters Responses of the Aryl Hydrocarbon Receptor Signaling Pathway in the Mouse Mammary Gland

    Article • Molecular Pharmacology, August 2007, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    David Earnest

  24. Circadian profiling of the transcriptome in NIH/3T3 fibroblasts: comparison with rhythmic gene expression in SCN2.2 cells and the rat SCN

    Article • Physiological Genomics, May 2007, American Physiological Society

    David Earnest

  25. Circadian clock and cell cycle gene expression in mouse mammary epithelial cells and in the developing mouse mammary gland

    Article • Developmental Dynamics, October 2005, Wiley

    David Earnest

  26. Circadian Regulation and Function of Voltage-Dependent Calcium Channels in the Suprachiasmatic Nucleus

    Article • Journal of Neuroscience, October 2005, Society for Neuroscience

    David Earnest

  27. Long-term effects of neonatal alcohol exposure on photic reentrainment and phase-shifting responses of the activity rhythm in adult rats

    Article • Alcohol, October 2005, Elsevier

    David Earnest

  28. Neonatal Alcohol Exposure Permanently Disrupts the Circadian Properties and Photic Entrainment of the Activity Rhythm in Adult Rats

    Article • Alcoholism Clinical and Experimental Research, October 2005, Wiley

    David Earnest

  29. Circadian rhythms from multiple oscillators: lessons from diverse organisms

    Article • Nature Reviews Genetics, July 2005, Springer Science + Business Media

    David Earnest

  30. Circadian profiling of the transcriptome in immortalized rat SCN cells

    Article • Physiological Genomics, May 2005, American Physiological Society

    David Earnest

  31. TrkB-deficient mice show diminished phase shifts of the circadian activity rhythm in response to light

    Article • Neuroscience Letters, April 2005, Elsevier

    David Earnest

  32. Overlap in the distribution of TrkB immunoreactivity and retinohypothalamic tract innervation of the rat suprachiasmatic nucleus

    Article • Neuroscience Letters, March 2005, Elsevier

    David Earnest

  33. Cell Culture Models for Oscillator and Pacemaker Function: Recipes for Dishes with Circadian Clocks?

    Article • January 2005, Elsevier

    David Earnest

  34. Melatonin desensitizes endogenous MT 2 melatonin receptors in the rat suprachiasmatic nucleus: relevance for defining the periods of sensitivity of the mammalian circadian clock to melatonin

    Article • The FASEB Journal, November 2004, Wiley

    David Earnest

  35. Developmental Alcohol Exposure Alters Light‐Induced Phase Shifts of the Circadian Activity Rhythm in Rats

    Article • Alcoholism Clinical and Experimental Research, July 2004, Wiley

    David Earnest

  36. Developmental alcohol exposure disrupts circadian regulation of BDNF in the rat suprachiasmatic nucleus

    Article • Neurotoxicology and Teratology, June 2004, Elsevier

    David Earnest

  37. Immortalized cells from the rat suprachiasmatic nucleus express functional melatonin receptors

    Article • Brain Research, March 2004, Elsevier

    David Earnest

  38. Effects of altered Clock gene expression on the pacemaker properties of SCN2.2 cells and oscillatory properties of NIH/3T3 cells

    Article • Neuroscience, January 2004, Elsevier

    David Earnest

  39. Regulation of basal rhythmicity in protein kinase C activity by melatonin in immortalized rat suprachiasmatic nucleus cells

    Article • Neuroscience Letters, July 2003, Elsevier

    David Earnest

  40. Real-time analysis of rhythmic gene expression in immortalized suprachiasmatic nucleus cells

    Article • Neuroreport, November 2002, Wolters Kluwer Health

    David Earnest

  41. Immortalized Suprachiasmatic Nucleus Cells Express Components of Multiple Circadian Regulatory Pathways

    Article • Biochemical and Biophysical Research Communications, March 2002, Elsevier

    David Earnest

  42. Establishment and characterization of adenoviral E1A immortalized cell lines derived from the rat suprachiasmatic nucleus

    Article • Journal of Neurobiology, April 1999, Wiley

    David Earnest

  43. Immortal Time: Circadian Clock Properties of Rat Suprachiasmatic Cell Lines

    Article • Science, January 1999, American Association for the Advancement of Science

    David Earnest

  44. Erratum

    Article • Neuroscience Letters, July 1998, Elsevier

    David Earnest

  45. Expression of Brain-Derived Neurotrophic Factor and Its Cognate Receptor, TrkB, in the Rat Suprachiasmatic Nucleus

    Article • Experimental Neurology, June 1998, Elsevier

    David Earnest

  46. Circadian rhythm of brain-derived neurotrophic factor in the rat suprachiasmatic nucleus

    Article • Neuroscience Letters, February 1998, Elsevier

    David Earnest

  47. Light induces expression of fos-related proteins within gastrin-releasing peptide neurons in the rat suprachiasmatic nucleus

    Article • Brain Research, November 1993, Elsevier

    David Earnest

  48. Rhythmic expression of Fos-related proteins within the rat suprachiasmatic nucleus during constant retinal illumination

    Article • Neuroscience Letters, June 1992, Elsevier

    David Earnest

  49. Effects of tetrodotoxin on the circadian pacemaker mechanism in suprachiasmatic explants in vitro

    Article • Brain Research Bulletin, May 1991, Elsevier

    David Earnest

  50. Photic regulation of c-fos expression in neural components governing the entrainment of circadian rhythms

    Article • Experimental Neurology, September 1990, Elsevier

    David Earnest

  51. Circadian vasopressin release from perifused rat suprachiasmatic explants in vitro: effects of acute stimulation

    Article • Brain Research, October 1987, Elsevier

    David Earnest

  52. A cholinergic antagonist, mecamylamine, blocks the phase-shifting effects of light on the circadian rhythm of locomotor activity in the golden hamster

    Article • Brain Research, February 1987, Elsevier

    Dr Joseph S Takahashi, David Earnest

  53. Circadian rhythms of vasopressin release from individual rat suprachiasmatic explants in vitro

    Article • Brain Research, September 1986, Elsevier

    David Earnest

  54. Responses of the split activity components in hamsters

    Article • The Science of Nature, September 1986, Springer Science + Business Media

    David Earnest

  55. Neurochemical basis for the photic control of circadian rhythms and seasonal reproductive cycles: role for acetylcholine.

    Article • Proceedings of the National Academy of Sciences, June 1985, Proceedings of the National Academy of Sciences

    David Earnest

  56. Periodic Exposure to a Brief Light Signal Stimulates Neuroendocrine‐Gonadal Activity in Golden Hamsters

    Article • Journal of Andrology, March 1984, Wiley

    David Earnest

  57. Effect of One-Second Light Pulses on Testicular Function and Locomotor Activity in the Golden Hamster 1

    Article • Biology of Reproduction, April 1983, Oxford University Press (OUP)

    David Earnest

  58. Role for Acetylcholine in Mediating Effects of Light on Reproduction

    Article • Science, January 1983, American Association for the Advancement of Science

    David Earnest

  59. Splitting of the circadian rhythm of activity in hamsters: Effects of exposure to constant darkness and subsequent re-exposure to constant light

    Article • Journal of Comparative Physiology A, January 1982, Springer Science + Business Media

    David Earnest