All Stories

  1. Hypophosphatasia: 90 Years from a Canadian Discovery—A Comprehensive Review of the APLP Gene Underlying Rathbun’s Syndrome
  2. Vitamin D and Pediatric Cancer Prevention: Dilemmas and Opportunities. A Systematic Review with A Critical Integrative Component
  3. Collagenous gastritis, hyperplastic polyp, and intraepithelial duodenal lymphocytosis in a 15-year-old child: An iconographic case report
  4. Liver Sinusoidal Endothelial Cells and Their Regulation of Immunology, Collagenization, and Bioreactivity in Fatty Liver: A Narrative Review
  5. The Influence of the Seasonal Variability of Candida spp. Bloodstream Infections and Antifungal Treatment: A Mediterranean Pilot Study
  6. Autosomal Dominant Polycystic Kidney Disease-Related Multifocal Renal Cell Carcinoma: A Narrative Iconographic Review
  7. Barth Syndrome: TAFAZZIN Gene, Cardiologic Aspects, and Mitochondrial Studies—A Comprehensive Narrative Review
  8. Inflammatory Pseudotumor of the Anal Canal Mimicking Colorectal Cancer: Case Report and Hints to Improve a Patient’s Fitness for Treatment and Prevention
  9. Basic implications on three pathways associated with SARS-CoV-2
  10. Seasonal Change in Microbial Diversity: Bile Microbiota and Antibiotics Resistance in Patients with Bilio-Pancreatic Tumors: A Retrospective Monocentric Study (2010–2020)
  11. Digging Through the Complexities of Immunological Approaches in Emerging Osteosarcoma Therapeutics: A Comprehensive Narrative Review with Updated Clinical Trials
  12. DICER1: The Argonaute Endonuclease Family Member and Its Role in Pediatric and Youth Pathology
  13. Mediastinal Teratoma with Nephroblastomatous Elements: Case Report, Literature Review, and Comparison with Maturing Fetal Glomerulogenic Zone/Definitive Zone Ratio and Nephrogenic Rests
  14. NAFLD (MASLD)/NASH (MASH): Does It Bother to Label at All? A Comprehensive Narrative Review
  15. The Impact of the Seasonal and Geographical Distribution of Tuberculosis in Sicily: A 6-Year Retrospective Study (2018–2023)
  16. Bioactivity, hemocompatibility, and inflammatory response of calcium incorporated sulfonated polyether ether ketone on mouse-derived bone marrow cells
  17. How MicroRNAs Command the Battle against Cancer
  18. Carney complex: A clinicopathologic study on a single family from several Canadian provinces
  19. Double Trouble: How Microbiome Dysbiosis and Mitochondrial Dysfunction Drive Non-Alcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis
  20. Microbial profile in bile from pancreatic and extra-pancreatic biliary tract cancer
  21. Investigating the Role of Non-Coding RNA in Non-Alcoholic Fatty Liver Disease
  22. Nickel’s carcinogenicity: the need of more studies to progress
  23. Rudolph Virchow’s Public Health Engagement and Theodor Khoury’s Legacy
  24. Liver Biopsy Handling of Metabolic-Associated Fatty Liver Disease (MAFLD): the Children’s Hospital of Eastern Ontario grossing protocol
  25. Ovomucin and its hydrolysates differentially influenced colitis severity in Citrobacter rodentium-infected mice
  26. Nanotechnology in the Horizon: The Introductory Editorial for Cellular and Molecular Medicine Research
  27. A Serological Analysis of the Humoral Immune Responses of Anti-RBD IgG, Anti-S1 IgG, and Anti-S2 IgG Levels Correlated to Anti-N IgG Positivity and Negativity in Sicilian Healthcare Workers (HCWs) with Third Doses of the mRNA-Based SARS-CoV-2 Vaccine: ...
  28. Stillbirth Investigations: An Iconographic and Concise Diagnostic Workup in Perinatal Pathology
  29. Pediatric Hepatic Angiosarcoma (PHAS) and Vinyl Chloride—A Ghost of the Past May Loom over East Palestine, OH, and beyond: A Critical Commentary
  30. Pediatric Echinococcosis of the Liver in Austria: Clinical and Therapeutical Considerations
  31. Demystifying neuroblastoma malignancy through fractal dimension, entropy, and lacunarity
  32. Mitochondrial Dysfunction and Induction of Apoptosis in Hepatocellular Carcinoma and Cholangiocarcinoma Cell Lines by Thymoquinone
  33. COVID-19 Molecular Pathophysiology: Acetylation of Repurposing Drugs
  34. Validation of testicular workup for ischemia and suspected torsion score in patients with acute scrotum
  35. Sanfilippo syndrome type A: early cardiac involvement of two patients with cardiac manifestations
  36. mRNA vaccination in children and youth: a cautionary note
  37. NLRP-3 Inflammasome: A Key Target, but Mostly Overlooked following SARS-CoV-2 Infection
  38. Life and Death Sometimes Coincide, and Pastoral Response is Crucial to the Brokenhearted
  39. Diverticular disease in a pediatric patient with Crohn’s disease mimicking a perforated post-appendectomy appendiceal stump
  40. Epigallocatechin gallate for Parkinson's disease
  41. Biliary Atresia Animal Models: Is the Needle in a Haystack?
  42. Communication in reporting the autopsy results is utmost
  43. Commentary on: SMARCB1 as a novel diagnostic and prognostic biomarker for osteosarcoma
  44. Acute Hepatitis of Unknown Origin (AHUO)—The Puzzle Ahead
  45. The Role of N6-Methyladenosine in the Promotion of Hepatoblastoma: A Critical Review
  46. Updates on Pediatric Hepatoblastoma
  47. Epithelial-mesenchymal transition, regulated by β-catenin and Twist, leads to esophageal wall remodeling in pediatric eosinophilic esophagitis
  48. ADPKD, COVID-19, and Apixaban: The Treacherous Intracystic Bleeding – A Letter on Apixaban Causing Hepatic Cystic Bleeding by Shehi et al.
  49. Astaxanthin for testicular torsion
  50. Implementing Epic Beaker Laboratory Information System for Diagnostics in Anatomic Pathology
  51. Regulation of the tumor suppressor PTEN in triple-negative breast cancer
  52. Biliary Atresia: A Complex Hepatobiliary Disease with Variable Gene Involvement, Diagnostic Procedures, and Prognosis
  53. Surgical Pathology Diagnostic Pitfalls of Hepatoblastoma
  54. Pathology and Anticatalysis treatment of exacerbated COVID-19
  55. Exposure to pesticides and pediatric Wilms’ tumor. A meta-analysis on pre-conception and pregnancy parental exposure with an IARC/WHO commentary
  56. Parental Pesticide Exposure and Childhood Brain Cancer: A Systematic Review and Meta-Analysis Confirming the IARC/WHO Monographs on Some Organophosphate Insecticides and Herbicides
  57. Transcriptome-Wide Analysis Reveals a Role for Extracellular Matrix and Integrin Receptor Genes in Otic Neurosensory Differentiation from Human iPSCs
  58. Targeting the ‘garbage-bin’ to fight cancer: HDAC6 inhibitor WT161 has an anti-tumor effect on osteosarcoma and synergistically interacts with 5-FU
  59. Vitamin D and Primary Ciliary Dyskinesia: A Topic to Be Further Explored
  60. Diffusion modeling of COVID-19 under lockdown
  61. The Position of the Heart During Normothermic Ex Situ Heart Perfusion is an Important Factor in Preservation and Recovery of Myocardial Function
  62. Hsp70 acts as a fine-switch that controls E3 ligase CHIP-mediated TAp63 and ΔNp63 ubiquitination and degradation
  63. Pirh2, an E3 ligase, regulates the AIP4–p73 regulatory pathway by modulating AIP4 expression and ubiquitination
  64. Human bile microbiota: A retrospective study focusing on age and gender
  65. Non-celiac wheat sensitivity: rationality and irrationality of a gluten-free diet in individuals affected with non-celiac disease: a review
  66. Lupus nephritis and Zimmerhackl’s legacy for histopathology: A milestone for clinical trials and reduction of interobserver disagreement
  67. The tumor microenvironment may trigger lymphoproliferation in cardiac myxoma
  68. Mathematical models in nursing research
  69. Specific Treatment exists for SARS-CoV-2 ARDS
  70. Specific Treatment exists for SARS-CoV-2 ARDS
  71. Cancer Stem Cells and their Management in Cancer Therapy
  72. Hypophosphatasia: The Unusual Presentation
  73. Targeting NLRP3 inflammasome in an animal model for Coronavirus Disease 2019 (COVID‐19) caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2)
  74. Face Masks Are Beneficial Regardless of the Level of Infection in the Fight Against COVID-19
  75. Low bone mineral density in HIV-positive young Italians and migrants
  76. Kefir microbial composition is a deciding factor in the physiological impact of kefir in a mouse model of obesity
  77. Association between factor V Leiden mutation and recurrent pregnancy loss in the middle east countries: a Newcastle–Ottawa meta-analysis
  78. MMP inhibitors attenuate doxorubicin cardiotoxicity by preventing intracellular and extracellular matrix remodeling
  79. Pediatrics: An Evolving Concept for the 21st Century
  80. Pediatric Sarcoidosis: A Review with Emphasis on Early Onset and High-Risk Sarcoidosis and Diagnostic Challenges
  81. Congenital Segmental Intestinal Dilatation: A 25-Year Review with Long-Term Follow-up at the Medical University of Innsbruck, Austria
  82. The microbiota of the bilio-pancreatic system: a cohort, STROBE-compliant study
  83. EPAS 1, congenital heart disease, and high altitude: disclosures by genetics, bioinformatics, and experimental embryology
  84. Endothelial cells of different organs exhibit heterogeneity in von Willebrand factor expression in response to hypoxia
  85. Tuberculosis evolution and climate change: How much work is ahead?
  86. Aluminum Exposure from Parenteral Nutrition: Early Bile Canaliculus Changes of the Hepatocyte
  87. Sialidosis: A Review of Morphology and Molecular Biology of a Rare Pediatric Disorder
  88. Fine Needle Aspiration Cytology for Neck Masses in Childhood. An Illustrative Approach
  89. Vanishing gastroschisis: Good outcome after a 10-year follow-up
  90. Bactibilia in diseases of the biliary tract and pancreatic gland in patients older than 80 years: a STROBE-retrospective cohort study in a teaching hospital in Italy
  91. Chloroquine-induced cardiomyopathy: a reversible cause of heart failure
  92. Antioxidants and Cancer: Theories, Techniques, and Trials in Preventing Cancer
  93. Co-ingestion of aspirin and acetaminophen promoting fulminant liver failure: A critical review of Reye syndrome in the current perspective at the dawn of the 21st century
  94. Co-ingestion of willow bark tea and acetaminophen associated with fatal infantile fulminant liver failure
  95. “English Disease”: Historical Notes on Rickets, the Bone–Lung Link and Child Neglect Issues
  96. Pediatric adrenal cortical carcinomas: Histopathological criteria and clinical trials. A systematic review
  97. Complete Maxillo-Mandibular Syngnathia in a Newborn with Multiple Congenital Malformations
  98. Hepatocellular Carcinoma, Fibrolamellar Variant: Diagnostic Pathologic Criteria and Molecular Pathology Update. A Primer
  99. Eosinophilic Esophagitis
  100. Malignant pleural mesothelioma in a child
  101. Adenovirus necrotizing hepatitis complicating atypical teratoid rhabdoid tumor
  102. Laboratory Procedures Update on Hirschsprung Disease
  103. Differential Expression of Sonic Hedgehog Protein in Human Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma
  104. R&D Implementation in a Department of Laboratory Medicine and Pathology: A Systematic Review Based on Pharmaceutical Companies
  105. Parenteral Soy Oil and Fish Oil Emulsions
  106. A Case of an Infant With Compound Heterozygous Mutations for Hypertrophic Cardiomyopathy Producing a Phenotype of Left Ventricular Noncompaction
  107. Factor V Leiden mutation in women with early recurrent pregnancy loss: a meta-analysis and systematic review of the causal association
  108. Mitochondriome and Cholangiocellular Carcinoma
  109. Anderson-Fabry cardiomyopathy: prevalence, pathophysiology, diagnosis and treatment
  110. Residues 240–250 in the C-Terminus of the Pirh2 Protein Complement the Function of the RING Domain in Self-Ubiquitination of the Pirh2 Protein
  111. A Balanced IL-1β Activity Is Required for Host Response to Citrobacter rodentium Infection
  112. Low-Dose Vasopressin Improves Cardiac Function in Newborn Piglets With Acute Hypoxia-Reoxygenation
  113. A case of lamin A/C mutation cardiomyopathy with overlap features of ARVC: A critical role of genetic testing
  114. Mimickers and tumours in the lower urinary tract: Need for a more efficient vigilance?
  115. Appendix carcinoids in childhood: Long-term experience at a single institution in Western Canada and systematic review
  116. Epithelial Cell Extrusion Leads to Breaches in the Intestinal Epithelium
  117. Recurrent anencephaly: A case report and examination of theVANGL1andFOXN1genes
  118. BMP-binding protein twisted gastrulation is required in mammary gland epithelium for normal ductal elongation and myoepithelial compartmentalization
  119. UBE4B: A Promising Regulatory Molecule in Neuronal Death and Survival
  120. Infantile myofibromatosis: report on a family with autosomal dominant inheritance and variable penetrance
  121. Branchiooculofacial Syndrome and Bilateral Ectopic Thymus: Report of a Family
  122. Holoprosencephaly-Polydactyly (Pseudotrisomy 13) Syndrome: Case Report and Diagnostic Criteria
  123. Angiogenic Remodeling in Pediatric EoE Is Associated With Increased Levels of VEGF-A, Angiogenin, IL-8, and Activation of the TNF-α–NFκB Pathway
  124. Sacrococcygeal Teratoma – a single center study of 43 years (1968–2011) including follow-up data and histopathological reevaluation of specimens
  125. FOXO3/FKHRL1 is activated by 5-aza-2-deoxycytidine and induces silenced caspase-8 in neuroblastoma
  126. Twisted gastrulation expression in cholangiocellular and hepatocellular carcinoma
  127. Clear Cell Variant of Embryonal Rhabdomyosarcoma: Report of an Unusual Retroperitoneal Tumor—Case Report and Literature Review
  128. Early versus delayed cyclosporine treatment in cardiac recovery and intestinal injury during resuscitation of asphyxiated newborn piglets
  129. OTX2mutations contribute to the otocephaly-dysgnathia complex
  130. Hepatic ultrastructure in a neonatal piglet model of intestinal failure-associated liver disease (IFALD)
  131. Canine Liver Transplantation Model and the Intermediate Filaments of the Cytoskeleton of the Hepatocytes
  132. Vasopressin improves systemic hemodynamics without compromising mesenteric perfusion in the resuscitation of asphyxiated newborn piglets: a dose–response study
  133. Mitochondrial DNA Depletion Syndrome-An Unusual Reason for Interstage Attrition after the Modified Stage 1 Norwood Operation
  134. Tolerability of inhaled N-chlorotaurine in an acute pig streptococcal lower airway inflammation model
  135. Medical management of motility disorders in patients with intestinal failure: a focus on necrotizing enterocolitis, gastroschisis, and intestinal atresia
  136. Familial adenomatous polyposis with concurrent metastatic appendiceal carcinoid and ovarian cystoadenoma
  137. Papillary renal cell carcinoma: report of a rare entity in childhood with review of the clinical management
  138. PRRX1 is mutated in a fetus with agnathia-otocephaly
  139. Decreased Apoptosis Despite Severe CD4 Depletion in the Thymus of a Human Immunodeficiency Virus-1 Infected Child
  140. Novel Neonatal Piglet Models of Surgical Short Bowel Syndrome With Intestinal Failure
  141. Mutations in WDR62, encoding a centrosome-associated protein, cause microcephaly with simplified gyri and abnormal cortical architecture
  142. The expression of twisted gastrulation in postnatal mouse brain and functional implications
  143. Solid-pseudopapillary tumor of the pancreas in a 12-year-old girl – 7 years follow-up and histopathological reevaluation: Case report and subject review
  144. Histology and synchrotron radiation-based microtomography of the inner ear in a molecularly confirmed case of CHARGE syndrome
  145. β-cell development and turnover during prenatal life in humans
  146. Epidermal Growth Factor Receptor Expression in Human Fetal Cochlea With Turner Syndrome
  147. The cochlea in fetuses with neural tube defects
  148. Tolerability of inhaled N-chlorotaurine in the pig model
  149. Immunohistochemical detection of polyductin and co-localization with liver progenitor cell markers during normal and abnormal development of the intrahepatic biliary system and in adult hepatobiliary carcinomas
  150. Successful treatment of severe juvenile microscopic polyangiitis with rituximab
  151. Discordant Outcomes in a Case of Parvovirus B19 Transmission Into Both Dichorionic Twins
  152. Does perinatal asphyxia induce apoptosis in the inner ear?
  153. Diagnosis of Hepatic Iron Overload
  154. Morphology Studies of the Human Fetal Cochlea in Turner Syndrome
  155. Pelizaeus Merzbacher disease: morphological analysis of the vestibulo-cochlear system
  156. Osteogenic sarcoma (osteosarcoma) in the elderly: Tumor delineation and predisposing conditions
  157. External quality assurance as a revalidation method for pathologists in pediatric histopathology: Comparison of four international programs
  158. Unravelling the parental origin and mechanism of formation of the 47,XY,i(X)(q10) Klinefelter karyotype variant
  159. Spatial and temporal dynamics of innervation during the development of fetal human pancreas
  160. Biliary-Type Cytokeratin Pattern in a Canine Isolated Perfused Liver Transplantation Model
  161. Bile duct to portal space ratio and ductal plate remnants in liver disease of infants aged less than 1 year
  162. Errata
  163. Congenital Fibrosarcoma as Cause for Fetal Anemia: Prenatal Diagnosis and in utero Treatment
  164. An Unusual Case of Intrauterine Symptomatic Neonatal Liver Failure
  165. Metastasizing Renal Cell Carcinoma Developing in a Congenital Ectopic and Dysplastic Kidney
  166. CD1a down-regulation in primary invasive ductal breast carcinoma may predict regional lymph node invasion and patient outcome
  167. Kidney transplantation in patients suffering from hereditary complete complement C4 deficiency
  168. Atrial natriuretic peptide and CD34 overexpression in human idiopathic dilated cardiomyopathies
  169. Fetal Distribution of 5α-Reductase 1 and 5α-Reductase 2, and Their Input on Human Prostate Development
  170. Pure esophageal atresia with normal outer appearance: case report
  171. Fatal circumstances of human herpesvirus 6 infection: transcriptosome data analysis suggests caution in implicating HHV-6 in the cause of death
  172. Pyridoxine-responsive seizures as the first symptom of infantile hypophosphatasia caused by two novel missense mutations (c.677T>C, p.M226T; c.1112C>T, p.T371I) of the tissue-nonspecific alkaline phosphatase gene
  173. Chemotherapeutic treatment of a pregnant patient with ovarian dysgerminoma
  174. Conjoined Epigastric Heteropagus Twins: Excision of a Parasitic Twin from the Anterior Abdominal Wall of Her Sibling
  175. Growth curves of the fetal prostate based on three-dimensional reconstructions: a correlation with gestational age and maternal testosterone levels
  176. Reevaluation of the Fetal Muscle Development of the Vesical Trigone
  177. Systemischer Lupus erythematodes im Kindes- und Jugendalter
  178. First localization and biochemical identification of chromogranin B- and secretoneurin-like immunoreactivity in the fetal human vagal/nucleus solitary complex
  179. Successful transplantation in a child with rapid progression of autosomal recessive polycystic kidney disease associated with a novel mutation
  180. Pregnancy outcomes in women with or without placental malaria infection
  181. Juvenile sarcoidosis presenting as Crohn’s Disease
  182. Nuclear Insulin-Like Growth Factor Binding Protein-3 Induces Apoptosis and Is Targeted to Ubiquitin/Proteasome–Dependent Proteolysis
  183. ARLTS1 variants and melanoma risk
  184. Comparative expression analysis of Pax3 and Pax7 during mouse myogenesis
  185. Local application of a collagen type I/hyaluronate matrix and growth and differentiation factor 5 influences the closure of osteochondral defects in a minipig model by enchondral ossification
  186. Single Nucleotide Polymorphisms (SNPs): History, Biotechnological Outlook and Practical Applications
  187. Use of Recombinant Factor VIIa(Novoseven??) in Combination with Other Coagulation Products Led to a Thrombotic Occlusion of the Truncus Brachiocephalicus in a Neonate Supported by Extracorporal Membrane Oxygenation
  188. DMBT1 expression and glycosylation during the adenoma–carcinoma sequence in colorectal cancer
  189. DETECTION OF CHLAMYDIA PNEUMONIAE IN LIVER TRANSPLANT PATIENTS WITH CHRONIC ALLOGRAFT REJECTION
  190. Effects of Local Application of Growth and Differentiation Factor-5 (GDF-5) in a Full-thickness Cartilage Defect Model
  191. Das Wachstumsfaktorkomposit aus GDF-5 und mineralisiertem Kollagen verbessert die Ausheilung einer H�ftkopfnekrose
  192. Human brain of preterm infants after hypoxic-ischaemic injuries: no evidence of a substantial role for apoptosis by using a fine-tuned ultrasound-guided neuropathological analysis
  193. Pathology Quiz Case
  194. Iron overload in adult Hfe-deficient mice independent of changes in the steady-state expression of the duodenal iron transporters DMT1 and Ireg1/ferroportin
  195. Severe Anemia in a 25-Day-Old Infant Due to Gastric Teratoma with Focal Neuroblastoma
  196. Agnathia-otocephaly complex: Report of three cases with involvement of two different Carnegie stages
  197. Identification of a CTL4 /Neu1 fusion transcript in a sialidosis patient
  198. A new animal model of femoral head necrosis induced by intraosseous injection of ethanol
  199. Eosinophilic Enterocolitis in a Patient With Rheumatoid Arthritis
  200. Single nucleotide insertion in the 5′-untranslated region of hepatitis C virus with clearance of the viral RNA in a liver transplant recipient during acute hepatitis B virus superinfection
  201. Prenatal diagnosis and fetal pathology in a Turkish family harboring a novel nonsense mutation in the lysosomal α-N-acetyl-neuraminidase (sialidase) gene
  202. Ellis-van Creveld syndrome: a generalized dysplasia of enchondral ossification
  203. Perinatal hypophosphatasia: Radiology, pathology and molecular biology studies in a family harboring a splicing mutation (648+1A) and a novel missense mutation (N400S) in the tissue-nonspecific alkaline phosphatase (TNSALP) gene
  204. Study of the Malformation of Ductal Plate of the Liver in Meckel Syndrome and Review of Other Syndromes Presenting with this Anomaly
  205. Akardius oder "Twin-Reversed-Arterial-Perfusion"-Sequenz
  206. The remodeling of the primitive human biliary system
  207. Central nervous system in twin reversed arterial perfusion sequence with special reference to examination of the brain in acardius anceps
  208. The central nervous system in microcephalic primordial dwarfism: Is there a characteristic developmental brain pathology in Seckel or Seckel-like syndrome?
  209. Norman-Roberts syndrome: prenatal diagnosis and autopsy findings
  210. Stage IIa Cervix Carcinoma with Metastasis to the Heart: Report of a Case with Immunohistochemistry, Flow Cytometry, and Virology Findings
  211. Huge Fetal Sacrococcygeal Teratoma with a Completely Formed Eye and Intratumoral DNA Ploidy Heterogeneity
  212. The distribution of HBV, HCV and HGV among livers with fulminant hepatic failure of different aetiology
  213. Short-rib-polydactyly syndrome type Verma-Naumoff-Le Marec in a fetus with histological hallmarks of type Saldino-Noonan but lacking internal organ abnormalities
  214. Ruhender Knorpel und Epiphysenfuge bei diastrophischer Dysplasie
  215. Utilization of magnetic resonance imaging in autopsy planning with specimen preservation for thoraco-omphalopagus symmetricus conjoined twins
  216. Case report: prenatal diagnosis of diastrophic dysplasia by ultrasound at 21 weeks of gestation in a mother with massive obesity
  217. Telencephalosynapsis (synencephaly) and rhombencephalosynapsis with posterior fossa ventriculocele (‘Dandy-Walker cyst’): an unusual aberrant syngenetic complex
  218. No association between genetic hemochromatosis and alpha1-antitrypsin deficienc
  219. Wilms' tumor arising in a multicystic kidney
  220. Purification of alpha-1-antitrypsin monomer by preparative electrophoresis.