All Stories

  1. Molecular biologic milieu in rhegmatogenous retinal detachment and proliferative vitreoretinopathy: a literature review

    Article • Ophthalmic Research, June 2022, Karger Publishers

    Professor Christos Kroupis

  2. The importance of aerobic capacity and nutrition in recreational master mountain runners’ performance and race-induced changes in body composition and biochemical blood indices

    Article • International Journal of Sports Science & Coaching, December 2021, SAGE Publications

    Professor Christos Kroupis

  3. Genotyping and Plasma/Cerebrospinal Fluid Profiling of a Cohort of Frontotemporal Dementia–Amyotrophic Lateral Sclerosis Patients

    Article • Brain Sciences, September 2021, MDPI AG

    Professor Christos Kroupis

  4. Global Longitudinal Strain of the Systemic Ventricle Is Correlated with Plasma Galectin-3 and Predicts Major Cardiovascular Events in Adult Patients with Congenital Heart Disease

    Article • Medicina, June 2020, MDPI AG

    Professor Christos Kroupis

  5. Validation and verification of examination procedures in medical laboratories: opinion of the EFLM Working Group Accreditation and ISO/CEN standards (WG-A/ISO) on dealing with ISO 15189:2012 demands for method verification and validation

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), February 2020, De Gruyter

    Dr Marc HM Thelen, Professor Christos Kroupis, Prof Dr em MD PhD EuSpcLM Florent JLA Vanstapel

  6. Functional characterization of CHEK2 variants in a Saccharomyces cerevisiae system

    Article • Human Mutation, March 2019, Wiley

    Professor Christos Kroupis

  7. Frontotemporal dementia spectrum: first genetic screen in a Greek cohort

    Article • Neurobiology of Aging, March 2019, Elsevier

    Professor Christos Kroupis

  8. Th17 serum cytokines in relation to laboratory‐confirmed respiratory viral infection: A pilot study

    Article • Journal of Medical Virology, February 2019, Wiley

    Professor Christos Kroupis

  9. Documenting metrological traceability as intended by ISO 15189:2012: A consensus statement about the practice of the implementation and auditing of this norm element

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), December 2018, De Gruyter

    Dr Marc HM Thelen, Professor Christos Kroupis, Prof Dr em MD PhD EuSpcLM Florent JLA Vanstapel

  10. A pilot plasma-ctDNA ring trial for the Cobas® EGFR Mutation Test in clinical diagnostic laboratories

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), September 2018, De Gruyter

    Professor Christos Kroupis

  11. Lazaroid (U-74389G) ameliorates lung injury due to lipid peroxidation and nitric oxide synthase-dependent reactive oxygen species generation caused by remote systematic ischemia-reperfusion following thoracoabdominal aortic occlusion

    Article • International Journal of Surgery, July 2018, Elsevier

    Professor Christos Kroupis

  12. Brain-derived neurotrophic factor (BDNF) in children with ASD and their parents: a 3-year follow-up

    Article • Acta Psychiatrica Scandinavica, March 2018, Wiley

    Professor Christos Kroupis

  13. Response to the letter to editor: Copeptin and its clinical implications in the setting of vasovagal syncope

    Article • International Journal of Cardiology, September 2017, Elsevier

    Professor Christos Kroupis

  14. Investigation of associations of ARMS2, CD14, and TLR4 gene polymorphisms with wet age-related macular degeneration in a Greek population

    Article • Clinical Ophthalmology, July 2017, Dove Medical Press

    Professor Christos Kroupis, IOSIF SKALIDAKIS

  15. Evaluation of the impact of tumor HPV status on outcome in patients with locally advanced unresectable head and neck squamous cell carcinoma (HNSCC) receiving cisplatin, 5-fluorouracil with or without docetaxel: a subset analysis of EORTC 24971 study

    Article • Annals of Oncology, June 2017, Oxford University Press (OUP)

    Professor Christos Kroupis

  16. Copeptin levels in patients with vasovagal syncope

    Article • International Journal of Cardiology, March 2017, Elsevier

    Professor Christos Kroupis

  17. AKT2 Gene Polymorphisms, sRANKL/OPG and Hormone Measurements in Polycystic Ovarian Syndrome (PCOS) Women

    Article • Clinical & Medical Biochemistry Open Access, January 2017, OMICS Publishing Group

    Professor Christos Kroupis

  18. Development and validation of molecular methodologies to assess PALB2 expression in sporadic breast cancer

    Article • Clinical Biochemistry, February 2016, Elsevier

    Professor Christos Kroupis

  19. Accreditation process in European countries – an EFLM survey

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), January 2016, De Gruyter

    Professor Christos Kroupis, Prof Dr em MD PhD EuSpcLM Florent JLA Vanstapel

  20. Recommendation for the review of biological reference intervals in medical laboratories

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), January 2016, De Gruyter

    Prof Dr em MD PhD EuSpcLM Florent JLA Vanstapel, Professor Christos Kroupis

  21. Circulating resistin is a significant predictor of mortality independently from cardiovascular comorbidities in elderly, non-diabetic subjects with chronic kidney disease

    Article • Biomarkers, December 2015, Informa Healthcare

    Professor Christos Kroupis, Professor Maria Dalamaga

  22. Evaluation of a particle enhanced turbidimetric assay for the measurement of neutrophil gelatinase-associated lipocalin in plasma and urine on Architect-8000: Analytical performance and establishment of reference values

    Article • Clinical Biochemistry, December 2015, Elsevier

    Professor Christos Kroupis

  23. Development of a novel PTT assay for mutation detection in PALB2 large exons and PALB2 screening in medullary breast cancer

    Article • Familial Cancer, November 2015, Springer Science + Business Media

    Professor Christos Kroupis

  24. Development of novel real-time PCR methodology for quantification of COL11A1 mRNA variants and evaluation in breast cancer tissue specimens

    Article • BMC Cancer, October 2015, Springer Science + Business Media

    Professor Christos Kroupis

  25. Non-invasive prenatal testing (NIPT): limitations on the way to become diagnosis

    Article • Diagnosis, September 2015, De Gruyter

    Professor Christos Kroupis

  26. Novel association of FCGR2A polymorphism with age-related macular degeneration (AMD) and development of a novel CFH real-time genotyping method

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), January 2015, De Gruyter

    Professor Christos Kroupis

  27. Flexible Scope for ISO15189 accreditation

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), January 2015, De Gruyter

    Professor Christos Kroupis, Dr Marc HM Thelen, Prof Dr em MD PhD EuSpcLM Florent JLA Vanstapel

  28. Oxidative stress in dry age-related macular degeneration and exfoliation syndrome

    Article • Critical Reviews in Clinical Laboratory Sciences, October 2014, Taylor & Francis

    Professor Christos Kroupis

  29. Validation of a Real-Time Quantitative Polymerase Chain Reaction Method for the Quantification of 3 Survivin Transcripts and Evaluation in Breast Cancer Tissues

    Article • Clinical Breast Cancer, April 2014, Elsevier

    Professor Christos Kroupis, Professor Maria Dalamaga

  30. Association of survivin splice variants with prognosis and treatment of breast cancer

    Article • World Journal of Clinical Oncology, January 2014, Baishideng Publishing Group Co., Limited (formerly WJG Press)

    Professor Christos Kroupis

  31. Molecular Genetics of Pseudoexfoliation Syndrome (PXFS) and Glaucoma(PXFG)

    Article • Journal of Genetic Syndromes & Gene Therapy, January 2013, OMICS Publishing Group

    Professor Christos Kroupis

  32. Serum markers of deranged myocardial collagen turnover: Their relation to malignant ventricular arrhythmias in cardioverter-defibrillator recipients with heart failure

    Article • American Heart Journal, October 2012, Elsevier

    Professor Christos Kroupis

  33. Cancer epigenomics: moving slowly, but at a steady pace from laboratory bench to clinical practice

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), January 2012, De Gruyter

    Professor Christos Kroupis

  34. Hereditary breast cancer: beyond BRCA genetic analysis; PALB2 emerges

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), January 2012, De Gruyter

    Professor Christos Kroupis

  35. Biomarkers in primary open angle glaucoma

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), January 2012, De Gruyter

    Professor Christos Kroupis

  36. Human papilloma virus (HPV) molecular diagnostics

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), January 2011, De Gruyter

    Professor Christos Kroupis

  37. Survivin isoforms and clinicopathological characteristics in colorectal adenocarcinomas using real-time qPCR

    Article • World Journal of Gastroenterology, January 2011, Baishideng Publishing Group Co., Limited (formerly WJG Press)

    Professor Christos Kroupis, Professor Maria Dalamaga

  38. Increased inflammatory Response in Patients With Dilated Cardiomyopathy Is Associated With Dyslipidemia: Effects of Statin Therapy

    Article • Angiology, December 2010, SAGE Publications

    Professor Christos Kroupis

  39. The Association Between a CommonFCGR2APolymorphism and C-Reactive Protein and Coronary Artery Disease Revisited

    Article • Genetic Testing and Molecular Biomarkers, December 2010, Mary Ann Liebert Inc

    Professor Christos Kroupis, Professor Maria Dalamaga

  40. PIK3CA Hotspot Mutation Scanning by a Novel and Highly Sensitive High-Resolution Small Amplicon Melting Analysis Method

    Article • Journal of Molecular Diagnostics, September 2010, Elsevier

    Professor Christos Kroupis, Panagiotis Vorkas

  41. P374 EPIGENETIC MODIFICATIONS IN HUMAN CAROTID ATHEROMATOUS PLAQUES

    Article • Atherosclerosis Supplements, June 2010, Elsevier

    Professor Christos Kroupis, Professor Maria Dalamaga

  42. Mutation scanning of exon 20 of the BRCA1 gene by high-resolution melting curve analysis

    Article • Clinical Biochemistry, January 2010, Elsevier

    Professor Christos Kroupis, Panagiotis Vorkas

  43. PI3K Pathway Activity and Response to First-Line Chemotherapy in Combination with Trastuzumab in Patients with HER2-Positive Metastatic Breast Cancer.

    Article • Cancer Research, December 2009, American Association for Cancer Research (AACR)

    Professor Christos Kroupis

  44. The Effect of Plasma Homocysteine Levels on Clinical Outcomes of Patients With Acute Lung Injury/Acute Respiratory Distress Syndrome

    Article • The American Journal of the Medical Sciences, December 2009, Elsevier

    Pantelis Bagos, Professor Christos Kroupis

  45. Development of a real-time PCR detection method for a FCGR2A polymorphism in the LightCycler and application in the heparin-induced thrombocytopenia syndrome

    Article • Clinical Biochemistry, November 2009, Elsevier

    Professor Christos Kroupis

  46. Serum oxidizability, total antioxidant status and albumin serum levels in patients with aneurysmal or arterial occlusive disease

    Article • Clinical Biochemistry, June 2008, Elsevier

    Professor Christos Kroupis, Professor Maria Dalamaga

  47. Asymmetric real-time PCR detection of BRCA1 5382insC mutation by melting curve analysis in the LightCycler

    Article • Clinica Chimica Acta, April 2008, Elsevier

    Professor Christos Kroupis

  48. Population-based study of human papillomavirus infection and cervical neoplasia in Athens, Greece

    Article • Epidemiology and Infection, June 2007, Cambridge University Press

    Professor Christos Kroupis

  49. The beneficial effects of the combined methods in investigating heparin-induced thrombocytopenia

    Article • Critical Care, January 2007, Springer Science + Business Media

    Professor Christos Kroupis

  50. Presence of high-risk human papillomavirus sequences in breast cancer tissues and association with histopathological characteristics

    Article • Clinical Biochemistry, July 2006, Elsevier

    Professor Christos Kroupis, Professor Maria Dalamaga

  51. Antiinflammatory Effects of Cardiac Resynchronization Therapy in Patients with Chronic Heart Failure

    Article • Pacing and Clinical Electrophysiology, March 2006, Wiley

    Professor Christos Kroupis

  52. Coronary and peripheral blood flow changes following biventricular pacing and their relation to heart failure improvement

    Article • EP Europace, January 2006, European Society of Cardiology

    Professor Christos Kroupis

  53. Real-Time Reverse Transcription-PCR Quantification of Vascular Endothelial Growth Factor Splice Variants

    Article • Clinical Chemistry, August 2005, AACC

    Professor Christos Kroupis

  54. Development and applications of a real-time quantitative RT-PCR method (QRT-PCR) for BRCA1 mRNA

    Article • Clinical Biochemistry, January 2005, Elsevier

    Professor Christos Kroupis

  55. Familial clustering of autoimmune diseases in patients with dilated cardiomyopathy

    Article • The American Journal of Cardiology, May 2004, Elsevier

    Professor Christos Kroupis

  56. Genetic counseling of medullary breast cancer patients

    Article • Clinical Genetics, March 2004, Wiley

    Professor Christos Kroupis

  57. P-470 Sustained improvement in peripheral immune responses by biventricular pacing and its association with exercise tolerance and quality of life

    Article • EP Europace, December 2003, European Society of Cardiology

    Professor Christos Kroupis

  58. P-230 The effect of biventricularpacing on serum levels of soluble cellular adhesion molecules is sustained following 3 months of therapy discontinuation

    Article • EP Europace, December 2003, European Society of Cardiology

    Professor Christos Kroupis

  59. P-168 BNP in biventricular pacing: Its association with functional status and inflammatory markers

    Article • EP Europace, December 2003, European Society of Cardiology

    Professor Christos Kroupis

  60. Prognostic significance of soluble interleukin-2 receptor levels in patients with dilated cardiomyopathy

    Article • European Journal of Clinical Investigation, June 2003, Wiley

    Professor Christos Kroupis

  61. 158 Growth hormone treatment reduces circulating inflammatory cytokines and improves left ventricular contractile performance in patients with dilated cardiomyopathy

    Article • European Journal of Heart Failure Supplements, June 2003, Oxford University Press (OUP)

    Professor Christos Kroupis

  62. Atypical Medullary Breast Carcinoma in a Family Carrying the 5382insC BRCA-1 Mutation

    Article • The Breast Journal, May 2003, Wiley

    Professor Christos Kroupis

  63. Sustained improvement in peripheral immune response by biventricular pacing and its association with exercise tolerance and quality of life

    Article • Journal of the American College of Cardiology, March 2003, Elsevier

    Professor Christos Kroupis

  64. Physical training-induced reduction of peripheral monocyte-related inflammatory markers is associated with improvement in endothelial function of chronic heart failure patients

    Article • Journal of the American College of Cardiology, March 2003, Elsevier

    Professor Christos Kroupis

  65. Immunomodulatory effects of growth hormone administration are associated with improvement in myocardial contractile performance in dilated cardiomyopathy patients

    Article • Journal of the American College of Cardiology, March 2003, Elsevier

    Professor Christos Kroupis

  66. Article • Cardiovascular Drugs and Therapy, January 2003, Springer Science + Business Media

    Professor Christos Kroupis

  67. Germ line BRCA1 & BRCA2 mutations in Greek breast/ovarian cancer families: 5382insC is the most frequent mutation observed

    Article • Cancer Letters, November 2002, Elsevier

    Professor Christos Kroupis

  68. Growth hormone administration reduces circulating proinflammatory cytokines and soluble Fas/soluble Fas ligand system in patients with chronic heart failure secondary to idiopathic dilated cardiomyopathy

    Article • American Heart Journal, August 2002, Elsevier

    Professor Christos Kroupis

  69. Physical training modulates proinflammatory cytokines and soluble fas-soluble fas ligand system in patients with chronic heart failure

    Article • Journal of the American College of Cardiology, March 2002, Elsevier

    Professor Christos Kroupis

  70. Physical training modulates proinflammatory cytokines and the soluble Fas/soluble Fasligand system in patients with chronic heart failure

    Article • Journal of the American College of Cardiology, February 2002, Elsevier

    Professor Christos Kroupis

  71. Hyperprolactinaemia in patients with heart failure: clinical and immunogenetic correlations

    Article • European Journal of Clinical Investigation, February 2002, Wiley

    Professor Christos Kroupis

  72. Physical training reduces peripheral markers of inflammation in patients with chronic heart failure

    Article • European Heart Journal, May 2001, European Society of Cardiology

    Professor Christos Kroupis

  73. Immune-genetic control of hyperprolactinemia in patients with heart failure and correlation with ventricular function Dennis Cokkinos, Constantinos Limas, Christos Kroupis, Antigoni Haidaroglou. Onassis Cardiac Surgery Center, Athens, Greece

    Article • Journal of the American College of Cardiology, February 2001, Elsevier

    Professor Christos Kroupis

  74. Cell adhesion molecules in relation to simvastatin and hormone replacement therapy in coronary artery disease

    Article • European Heart Journal, June 2000, European Society of Cardiology

    Professor Christos Kroupis

  75. Physical training reduces circulating monocyte-endothelial cell adhesive interaction markers in patients with chronic heart failure

    Article • European Journal of Heart Failure, June 2000, Wiley

    Professor Christos Kroupis

  76. Effects of growth hormone treatment on circulating proinflammatory cytokines and soluble apoptosis receptor Fas in patients with dilated cardiomyopathy

    Article • European Journal of Heart Failure, June 2000, Wiley

    Professor Christos Kroupis

  77. BRCA1 mutation analysis in breast/ovarian cancer families from Greece

    Article • Human Mutation, January 2000, Wiley

    Professor Christos Kroupis

  78. Prevalence of factor V Leiden, prothrombin G20210A, and MTHFR C677T mutations in a Greek population of blood donors

    Article • American Journal of Hematology, August 1999, Wiley

    Professor Christos Kroupis

  79. Effect of Cyclosporine and Sirolimus on Interleukin-15–Driven Proliferation of OKT3-Preactivated Human Lymphocytes

    Article • Transplantation Proceedings, June 1998, Elsevier

    Professor Christos Kroupis

  80. ATP-dependent Regulation of Sodium-Calcium Exchange in Chinese Hamster Ovary Cells Transfected with the Bovine Cardiac Sodium-Calcium Exchanger

    Article • Journal of Biological Chemistry, April 1995, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Christos Kroupis

  81. Dimerization of Thermomonospora fusca .beta.-1,4-endoglucanase E2

    Article • Biochemistry, August 1993, American Chemical Society (ACS)

    David Wilson, Professor Christos Kroupis

  82. Cloning and expression of the bovine cardiac sodium-calcium exchanger

    Article • Archives of Biochemistry and Biophysics, November 1992, Elsevier

    Professor Christos Kroupis