All Stories

  1. Exploring the outer limits of polyplexes

    Article • Biochemical and Biophysical Research Communications, October 2023, Elsevier

    Dr. Archibald J Mixson

  2. Delivery of Chemotherapy Agents and Nucleic Acids with pH-Dependent Nanoparticles

    Article • Pharmaceutics, May 2023, MDPI AG

    Dr. Archibald J Mixson

  3. pH-Sensitive Targeting of Tumors with Chemotherapy-Laden Nanoparticles: Progress and Challenges

    Article • Pharmaceutics, November 2022, MDPI AG

    Dr. Archibald J Mixson

  4. Marked increase in tumor transfection with a truncated branched polymer

    Article • The Journal of Gene Medicine, November 2021, Wiley

    Dr. Archibald J Mixson

  5. Location of a single histidine within peptide carriers increases mRNA delivery

    Article • The Journal of Gene Medicine, December 2020, Wiley

    Dr. Archibald J Mixson

  6. The Multifaceted Histidine-Based Carriers for Nucleic Acid Delivery: Advances and Challenges

    Article • Pharmaceutics, August 2020, MDPI AG

    Dr. Archibald J Mixson

  7. Enhanced tumor uptake and activity of nanoplex-loaded doxorubicin

    Article • Biochemical and Biophysical Research Communications, May 2019, Elsevier

    Dr. Archibald J Mixson

  8. Targeting Cancer with Peptide RNAi Nanoplexes

    Article • January 2019, Springer Science + Business Media

    Dr. Archibald J Mixson

  9. Advances in Delivery Systems for Doxorubicin

    Article • Journal of Nanomedicine & Nanotechnology, January 2018, OMICS Publishing Group

    Dr. Archibald J Mixson

  10. Simultaneous silencing of TGF-β1 and COX-2 reduces human skin hypertrophic scar through activation of fibroblast apoptosis

    Article • Oncotarget, September 2017, Impact Journals, LLC

    Dr. Archibald J Mixson

  11. Targeted Delivery of siRNA Therapeutics to Malignant Tumors

    Article • Journal of Drug Delivery, January 2017, Hindawi Publishing Corporation

    Dr. Archibald J Mixson

  12. NRP1 transport of cancer therapeutics mediated by tumor-penetrating peptides

    Article • Drugs of the Future, January 2017, Prous Science

    Dr. Archibald J Mixson

  13. Targeing Invasive Fungi with the Silver-Bullet Peptide

    Article • Biochemical and Biophysical Research Communications, September 2016, Elsevier

    Dr. Archibald J Mixson

  14. NRP-1 mediated transport of H2K polyplexes to tumors

    Article • The Journal of Gene Medicine, July 2016, Wiley

    Dr. Archibald J Mixson

  15. siRNA nanoparticles: the future of RNAi therapeutics for oncology?

    Article • Nanomedicine, October 2014, Future Medicine

    Dr. Archibald J Mixson

  16. Increased tumor distribution and expression of histidine-rich plasmid polyplexes

    Article • The Journal of Gene Medicine, September 2014, Wiley

    Dr. Archibald J Mixson

  17. Direct Observation of Dynamic Mechanical Regulation of DNA Condensation by Environmental Stimuli

    Article • Angewandte Chemie International Edition, August 2014, Wiley

    Dr. Archibald J Mixson

  18. Enhancement of antifungal activity by integrin-targeting of branched histidine rich peptides

    Article • Journal of Drug Targeting, April 2014, Taylor & Francis

    Dr. Archibald J Mixson

  19. Enhanced silencing and stabilization of siRNA polyplexes by histidine-mediated hydrogen bonds

    Article • Biomaterials, January 2014, Elsevier

    Dr. Archibald J Mixson

  20. Surface-Modified HK:siRNA Nanoplexes with Enhanced Pharmacokinetics and Tumor Growth Inhibition

    Article • Biomacromolecules, February 2013, American Chemical Society (ACS)

    Dr. Archibald J Mixson

  21. Buffering Capacity and Size of siRNA Polyplexes Influence Cytokine Levels

    Article • Molecular Therapy, December 2012, Elsevier

    Dr. Archibald J Mixson

  22. Zinc finger nucleases: Tailor-made for gene therapy

    Article • Drugs of the Future, January 2012, Prous Science

    Dr. Archibald J Mixson

  23. Selective modification of HK peptides enhances siRNA silencing of tumor targets in vivo

    Article • Cancer Gene Therapy, August 2011, Springer Science + Business Media

    Dr. Archibald J Mixson

  24. Vaccines targeting the neovasculature of tumors

    Article • Vascular Cell, January 2011, Publiverse Online S.R.L

    Dr. Archibald J Mixson

  25. Peptide-based antifungal therapies against emerging infections

    Article • Drugs of the Future, January 2010, Prous Science

    Dr. Archibald J Mixson

  26. Leveraging therapeutic potential of multi-targeted siRNA inhibitors

    Article • Future Medicinal Chemistry, December 2009, Future Science

    Dr. Archibald J Mixson

  27. Advances in systemic siRNA delivery

    Article • Drugs of the Future, January 2009, Prous Science

    Dr. Archibald J Mixson

  28. Human rhomboid family-1 gene silencing causes apoptosis or autophagy to epithelial cancer cells and inhibits xenograft tumor growth

    Article • Molecular Cancer Therapeutics, June 2008, American Association for Cancer Research (AACR)

    Dr. Archibald J Mixson

  29. Systemic delivery of HK Raf-1 siRNA polyplexes inhibits MDA-MB-435 xenografts

    Article • Cancer Gene Therapy, May 2008, Nature

    Dr. Archibald J Mixson

  30. Histidine-lysine peptides as carriers of nucleic acids

    Article • Drug News & Perspectives, January 2007, Prous Science

    Dr. Archibald J Mixson

  31. Synthetic Histidine-Rich Peptides Inhibit Candida Species and Other Fungi In Vitro: Role of Endocytosis and Treatment Implications

    Article • Antimicrobial Agents and Chemotherapy, August 2006, ASM Journals

    Dr. Archibald J Mixson

  32. 203. Salt Conditions during Polyplex Formation Significantly Alters Transfection

    Article • Molecular Therapy, January 2006, Elsevier

    Dr. Archibald J Mixson

  33. A branched histidine/lysine peptide, H2K4b, in complex with plasmids encoding antitumor proteins inhibits tumor xenografts

    Article • The Journal of Gene Medicine, January 2006, Wiley

    Dr. Archibald J Mixson

  34. Transporting silence: Design of carriers for siRNA to angiogenic endothelium

    Article • Journal of Controlled Release, December 2005, Elsevier

    Professor Raymond Schiffelers, Dr. Archibald J Mixson

  35. Small interfering RNA targeting Raf-1 inhibits tumor growth in vitro and in vivo

    Article • Cancer Gene Therapy, April 2005, Springer Science + Business Media

    Dr. Archibald J Mixson

  36. Modified branched peptides with a histidine-rich tail enhance in vitro gene transfection

    Article • Nucleic Acids Research, February 2005, Oxford University Press (OUP)

    Dr. Archibald J Mixson

  37. Alteration in the IL-2 signal peptide affects secretion of proteinsin vitro andin vivo

    Article • The Journal of Gene Medicine, January 2005, Wiley

    Dr. Archibald J Mixson

  38. Highly branched HK peptides are effective carriers of siRNA

    Article • The Journal of Gene Medicine, January 2005, Wiley

    Dr. Archibald J Mixson

  39. Optimal transfection with the HK polymer depends on its degree of branching and the pH of endocytic vesicles

    Article • Nucleic Acids Research, March 2002, Oxford University Press (OUP)

    Dr. Archibald J Mixson

  40. Targeting Tumor Angiogenesis with Gene Therapy

    Article • Molecular Genetics and Metabolism, September 2001, Elsevier

    Dr. Archibald J Mixson

  41. Branched co-polymers of histidine and lysine are efficient carriers of plasmids

    Article • Nucleic Acids Research, March 2001, Oxford University Press (OUP)

    Dr. Archibald J Mixson

  42. Co-polymer of histidine and lysine markedly enhances transfection efficiency of liposomes

    Article • Gene Therapy, October 2000, Springer Science + Business Media

    Dr. Archibald J Mixson

  43. Antiangiogenic Gene Therapy in Cancer

    Article • Current Genomics, September 2000, Bentham Science Publishers

    Dr. Archibald J Mixson

  44. In VivoGene Therapy with a Cationic Polymer Markedly Enhances the Antitumor Activity of Antiangiogenic Genes

    Article • Molecular Genetics and Metabolism, July 1998, Elsevier

    Dr. Archibald J Mixson

  45. Gene Therapy with P53 and a Fragment of Thrombospondin I Inhibits Human Breast Cancerin Vivo

    Article • Molecular Genetics and Metabolism, February 1998, Elsevier

    Dr. Archibald J Mixson

  46. Systemic gene therapy with p53 inhibits breast cancer recent advances and therapeutic implications

    Article • Frontiers in Bioscience, January 1998, Frontiers in Bioscience

    Dr. Archibald J Mixson

  47. Parenteral Gene Therapy with p53 Inhibits Human Breast TumorsIn VivoThrough a Bystander Mechanism Without Evidence of Toxicity

    Article • Human Gene Therapy, January 1997, Mary Ann Liebert Inc

    Dr. Archibald J Mixson

  48. Systemic Gene Therapy with p53 Reduces Growth and Metastases of a Malignant Human Breast Cancer in Nude Mice

    Article • Human Gene Therapy, April 1995, Mary Ann Liebert Inc

    Dr. Archibald J Mixson

  49. ADHD AND THE THYROID CONTROVERSY

    Article • Journal of the American Academy of Child & Adolescent Psychiatry, June 1994, Elsevier

    Dr. Archibald J Mixson

  50. Analysis of the binding of 3,3',5-triiodo-L-thyronine and its analogs to mutant human .beta.1 thyroid hormone receptors: A model of the hormone binding site

    Article • Biochemistry, April 1994, American Chemical Society (ACS)

    Dr. Archibald J Mixson

  51. Differential expression of mutant and normal beta T3 receptor alleles in kindreds with generalized resistance to thyroid hormone.

    Article • Journal of Clinical Investigation, May 1993, American Society for Clinical Investigation

    Dr. Archibald J Mixson

  52. Attention Deficit-Hyperactivity Disorder in People with Generalized Resistance to Thyroid Hormone

    Article • New England Journal of Medicine, April 1993, New England Journal of Medicine (NEJM/MMS)

    Dr. Archibald J Mixson

  53. Identification of a novel mutation in the gene encoding the β-triiodothyronine receptor in a patient with apparent selective pituitary resistance to thyroid hormone

    Article • Clinical Endocrinology, March 1993, Wiley

    Dr. Archibald J Mixson

  54. Thyrotropin-secreting pituitary carcinoma

    Article • The Journal of Clinical Endocrinology & Metabolism, February 1993, Endocrine Society

    Dr. Archibald J Mixson

  55. Thyrotropin-secreting pituitary carcinoma.

    Article • The Journal of Clinical Endocrinology & Metabolism, February 1993, Endocrine Society

    Dr. Archibald J Mixson

  56. The proto-oncogenes c-fos and c-jun modulate thyroid hormone inhibition of human thyrotropin β subunit gene expression in opposite directions

    Article • Biochemical and Biophysical Research Communications, December 1992, Elsevier

    Dr. Archibald J Mixson

  57. Correlations of language abnormalities with localization of mutations in the beta-thyroid hormone receptor in 13 kindreds with generalized resistance to thyroid hormone: identification of four new mutations

    Article • The Journal of Clinical Endocrinology & Metabolism, October 1992, Endocrine Society

    Dr. Archibald J Mixson

  58. Correlations of language abnormalities with localization of mutations in the beta-thyroid hormone receptor in 13 kindreds with generalized resistance to thyroid hormone: identification of four new mutations.

    Article • The Journal of Clinical Endocrinology & Metabolism, October 1992, Endocrine Society

    Dr. Archibald J Mixson

  59. Characterization of seven novel mutations of the c-erbA beta gene in unrelated kindreds with generalized thyroid hormone resistance. Evidence for two "hot spot" regions of the ligand binding domain.

    Article • Journal of Clinical Investigation, December 1991, American Society for Clinical Investigation

    Dr. Archibald J Mixson

  60. Structural analogues of pyrroline 5-carboxylate specifically inhibit its uptake into cells

    Article • The Journal of Membrane Biology, May 1991, Springer Science + Business Media

    Dr. Archibald J Mixson

  61. An Assay for Pyrroline 5-Carboxylate Based on its Interaction with Cysteine

    Article • Analytical Letters, April 1991, Taylor & Francis

    Dr. Archibald J Mixson

  62. The uptake of pyrroline 5-carboxylate. Group translocation mediating the transfer of reducing-oxidizing potential.

    Article • Journal of Biological Chemistry, August 1988, Elsevier

    Dr. Archibald J Mixson

  63. DNA Delivery to Cells in Culture Using Peptides

    Article • Springer Science + Business Media

    Dr. Archibald J Mixson

  64. Inhibiting Cancer Angiogenesis With Molecular Therapy

    Article • Springer Science + Business Media

    Dr. Archibald J Mixson