All Stories

  1. Effects of age and genetic variations in VKORC1, CYP2C9 and CYP3A4 on the phenprocoumon dose in pediatric patients
  2. Gastrointestinal toxicity among patients taking selective COX-2 inhibitors or conventional NSAIDs, alone or combined with proton pump inhibitors: a case-control study
  3. Risk of fracture in patients with Charcot–Marie–Tooth disease
  4. Safety information on QT-interval prolongation: comparison of European Union and United States drug labeling
  5. CYP2C19 genotype–guided antiplatelet therapy in ST-segment elevation myocardial infarction patients—Rationale and design of the Patient Outcome after primary PCI (POPular) Genetics study
  6. Exploring interaction effects in small samples increases rates of false-positive and false-negative findings: results from a systematic review and simulation study
  7. Pharmacogenetic‐guided dosing of coumarin anticoagulants: algorithms for warfarin, acenocoumarol and phenprocoumon
  8. Pharmacogenomics of oral antiplatelet drugs
  9. Essential Medicines Are More Available than Other Medicines around the Globe
  10. Disease History and Medication Use as Risk Factors for the Clinical Manifestation of Type 1 Diabetes in Children and Young Adults: An Explorative Case Control Study
  11. Propensity score balance measures in pharmacoepidemiology: a simulation study
  12. Changes in Mortality Patterns Following Total Hip or Knee Arthroplasty Over the Past Two Decades: A Nationwide Cohort Study
  13. CARING (CAncer Risk and INsulin analoGues): The Association of Diabetes Mellitus and Cancer Risk with Focus on Possible Determinants - A Systematic Review and a Meta-Analysis
  14. A Randomized Trial of Genotype-Guided Dosing of Acenocoumarol and Phenprocoumon
  15. Performance of instrumental variable methods in cohort and nested case–control studies: a simulation study
  16. Robust association of the LPA locus with low-density lipoprotein cholesterol lowering response to statin treatment in a meta-analysis of 30 467 individuals from both randomized control trials and observational studies and association with coronary arte...
  17. Five-year fracture risk estimation in patients with Parkinson's disease
  18. Risk of Gastrointestinal Bleeding in Patients Undergoing Total Hip or Knee Replacement Compared With Matched Controls: A Nationwide Cohort Study
  19. Unravelling Drug Reimbursement Outcomes: A Comparative Study of the Role of Pharmacoeconomic Evidence in Dutch and Swedish Reimbursement Decision Making
  20. Increased Risk of Sudden Cardiac Arrest in Obstructive Pulmonary Disease: A Case-Control Study
  21. Cost–effectiveness of pharmacogenetic-guided dosing of phenprocoumon in atrial fibrillation
  22. Should non-inferiority drug trials be banned altogether?
  23. Phase IV non-inferiority trials and additional claims of benefit
  24. Use of Oral Glucocorticoids and the Risk of Pulmonary Embolism
  25. Expert-opinion on non-inferiority margin: A case study of oral anti-coagulant agents for prophylaxis of venous thromboembolic events after orthopedic surgery
  26. Number of Patients Studied Prior to Approval of New Medicines: A Database Analysis
  27. Pharmacogenetics of ACE inhibitor-induced angioedema and cough: a systematic review and meta-analysis
  28. Electrocardiographic Characteristics of Patients with Chronic Obstructive Pulmonary Disease
  29. Evaluation of the effect of genetic variations inGATA-4on the phenprocoumon and acenocoumarol maintenance dose
  30. The effect of omeprazole and esomeprazole on the maintenance dose of phenprocoumon
  31. Cardiac Arrhythmias in Adult Patients with Asthma
  32. Evaluation of the effect of statin use on the acenocoumarol and phenprocoumon maintenance dose
  33. Timing of Acute Myocardial Infarction in Patients Undergoing Total Hip or Knee Replacement
  34. Cost–effectiveness of pharmacogenetics in anticoagulation: international differences in healthcare systems and costs
  35. Relative Effectiveness Assessment of Pharmaceuticals: Similarities and Differences in 29 Jurisdictions
  36. Validation of the acenocoumarol EU-PACT algorithms: similar performance in the Rotterdam Study cohort as in the original study
  37. Correction: Differential Changes in QTc Duration during In-Hospital Haloperidol Use
  38. Correction: Common Variants in the Type 2 Diabetes KCNQ1 Gene Are Associated with Impairments in Insulin Secretion During Hyperglycaemic Glucose Clamp
  39. Cardiovascular Pharmacogenetics
  40. Future of Pharmacogenetics in Cardiovascular Diseases
  41. Common Variants in the Type 2 Diabetes KCNQ1 Gene Are Associated with Impairments in Insulin Secretion During Hyperglycaemic Glucose Clamp
  42. The influence of CYP2C19*2 and *17 on on-treatment platelet reactivity and bleeding events in patients undergoing elective coronary stenting
  43. When to publish measures of disproportionality derived from spontaneous reporting databases?
  44. Acid suppressants and hip fracture: Duplicate publication bias?
  45. Balance measures for propensity score methods: a clinical example on beta‐agonist use and the risk of myocardial infarction
  46. Differential Changes in QTc Duration during In-Hospital Haloperidol Use
  47. Implementation of pharmacogenetics in clinical practice is challenging
  48. Genetic variability within the cholesterol lowering pathway and the effectiveness of statins in reducing the risk of MI
  49. Measuring balance and model selection in propensity score methods
  50. Insomnia medication: Do published studies reflect the complete picture of efficacy and safety?
  51. Influence of the use of functional foods enriched with phytosterols/‐stanols on adherence to statin therapy
  52. Time‐trends in treatment and cardiovascular events in patients with heart failure: a pharmacosurveillance study
  53. Non‐steroidal anti‐inflammatory drugs and risk of pulmonary embolism
  54. CYP2C19 and ABCB1 genes and individualized treatment with clopidogrel
  55. Non‐selective vs. selective beta‐blocker treatment and the risk of thrombo‐embolic events in patients with heart failure
  56. Sulfonylureas and on-clopidogrel platelet reactivity in type 2 diabetes mellitus patients
  57. Variants of ADAMTS1 modify the effectiveness of statins in reducing the risk of myocardial infarction
  58. Influence of Intensive versus Conventional Glucose Control on Microvascular and Macrovascular Complications in Type 1 and 2 Diabetes Mellitus
  59. Room for Improvement in Conducting and Reporting Non-Inferiority Randomized Controlled Trials on Drugs: A Systematic Review
  60. Pharmacogenetic interactions betweenABCB1andSLCO1B1tagging SNPs and the effectiveness of statins in the prevention of myocardial infarction
  61. Clinical and economic consequences of pharmacogenetic-guided dosing of warfarin
  62. A systematic review of cost–effectiveness analyses of pharmacogenetic-guided dosing in treatment with coumarin derivatives
  63. Use of Organic Nitrates and the Risk of Hip Fracture: A Population-Based Case-Control Study
  64. NON-SELECTIVE BETA-BLOCKERS DECREASE THROMBOTIC EVENTS IN PATIENTS WITH HEART FAILURE
  65. TIME TRENDS IN CARDIOVASCULAR DRUG TREATMENT AND CARDIOVASCULAR EVENTS IN PATIENTS WITH ACUTE HEART FAILURE
  66. Methodological and statistical issues in pharmacogenomics
  67. Genetic polymorphisms related to the renin–angiotensin–aldosterone system and response to antihypertensive drugs
  68. Besides CYP2C19*2, the variant allele CYP2C9*3 is associated with higher on-clopidogrel platelet reactivity in patients on dual antiplatelet therapy undergoing elective coronary stent implantation
  69. Genotype-guided dosing of coumarin derivatives: the European pharmacogenetics of anticoagulant therapy (EU-PACT) trial design
  70. Systematic Review of Pharmacogenetic Warfarin Dosing
  71. Genetic determinants of response to statins
  72. Clinical impact of adducin polymorphism
  73. Reasons for non‐response in observational pharmacogenetic research
  74. Pharmacogenomic insights into treatment and management of statin-induced myopathy
  75. Interaction between the Gly460Trp α-adducin gene variant and diuretics on the risk of myocardial infarction
  76. Recruitment of participants through community pharmacies for a pharmacogenetic study of antihypertensive drug treatment
  77. Effect of oral antiplatelet agents on major bleeding in users of coumarins
  78. Comparison of knowledge and accessibility to information sources of HIV/AIDS between blind and sighted populations in Nigeria
  79. Pharmacogenomics of coumarin anticoagulants: Are we underestimating the role of CYP2C9?
  80. Effectiveness of statins in the reduction of the risk of myocardial infarction is modified by the GNB3 C825T variant
  81. Comparison of different pain scoring systems in critically ill patients in a general ICU
  82. Comparing treatment effects after adjustment with multivariable Cox proportional hazards regression and propensity score methods
  83. Society already achieves economic benefits from generic substitution but fails to do the same for therapeutic substitution
  84. Pharmacogenetics of Glucose-Lowering Drug Treatment
  85. Rates and determinants of reinitiating antihypertensive therapy after prolonged stoppage: a population-based study
  86. Coumarin anticoagulants and co-trimoxazole: avoid the combination rather than manage the interaction
  87. Angiotensinogen M235T polymorphism and the risk of myocardial infarction and stroke among hypertensive patients on ACE-inhibitors or β-blockers
  88. Economic Evaluations of Cholesterol-Lowering Drugs
  89. Discrepancies between medication records of anticoagulation clinics and pharmacy records
  90. Apoliprotein-E polymorphism and response to pravastatin in men with coronary artery disease (REGRESS)
  91. The influence of the alpha-adducin G460W polymorphism and angiotensinogen M235T polymorphism on antihypertensive medication and blood pressure
  92. Instrumental Variables
  93. Initial non‐compliance with antihypertensive monotherapy is followed by complete discontinuation of antihypertensive therapy
  94. Prescribing behaviour according to Dutch and European guidelines on the management of hypercholesterolaemia (1992–1999)
  95. Improving Pharmacotherapy After Myocardial Infarction by Group Academic Detailing Using Feedback Data on a Patient Level
  96. Refill persistence with chronic medication assessed from a pharmacy database was influenced by method of calculation
  97. A Comparison of Two Multiple-Characteristic Decision-Making Models for the Comparison of Antihypertensive Drug Classes
  98. Rate and determinants of 10-year persistence with antihypertensive drugs
  99. Preventive drug use in patients with a history of nonfatal myocardial infarction during 12-year follow-up in The Netherlands: A retrospective analysis
  100. Cardiovascular drug use and differences in the incidence of cardiovascular mortality in elderly Serbian men
  101. Suboptimal choices and dosing of statins at start of therapy
  102. Genetic Polymorphisms and Response to HMG-CoA Reductase Inhibitors
  103. Discontinuation of rivastigmine in routine clinical practice
  104. Pharmacogenetics in health-care practice
  105. Should rosuvastatin be withdrawn from the market?
  106. Decrease of antiparkinsonian drugs before start of an antipsychotic in patients on levodopa treatment?
  107. The association between compliance with antihypertensive drugs and modification of antihypertensive drug regimen
  108. Pre-randomization decisions and group stratification in a randomized controlled trial to improve prescribing
  109. Recent trends in (under)treatment of hypercholesterolaemia in the Netherlands
  110. Comparison of two methodologies to analyze exposure to statins in an observational study on effectiveness
  111. Pharmacoeconomic evaluation of testing for angiotensin-converting enzyme genotype before starting ??-hydroxy-??-methylglutaryl coenzyme A reductase inhibitor therapy in men
  112. Failure to Continue Lipid-Lowering Drug Use Following the Withdrawal of Cerivastatin
  113. Drug-Gene Interactions between Genetic Polymorphisms and Antihypertensive Therapy
  114. Drug Therapy for Prevention of Recurrent Myocardial Infarction
  115. Adherence to and dosing of ??-hydroxy-??-methylglutaryl coenzyme A reductase inhibitors in the general population differs according to apolipoprotein E-genotypes
  116. Oral Antithrombotic Use Among Myocardial Infarction Patients
  117. Pharmacotherapy of Hospitalised HIV-Infected Patients in a General Hospital during 1990, 1997 and 2001
  118. Myopathy Due to Statin/Fibrate Use in the Netherlands
  119. Adherence to and dosing of statins differs according to apolipoprotein E-genotypes
  120. The effectiveness of hydroxy-methylglutaryl coenzyme A reductase inhibitors (statins) in the elderly is not influenced by apolipoprotein E genotype
  121. Genetic polymorphisms: importance for response to HMG-CoA reductase inhibitors
  122. Authorʼs Reply:
  123. The effectiveness of HMG‐CoA reductase inhibitors in an elderly population is independent of apolipoprotein E‐genotypes
  124. Lipid-Lowering Drug Use and Cardiovascular Events after Myocardial Infarction
  125. Time trends in lipid lowering drug use in The Netherlands. Has the backlog of candidates for treatment been eliminated?
  126. Antipsychotic-induced extrapyramidal syndromes and cytochrome P450 2D6 genotype: a case–control study
  127. Discrepancies between Medical and Pharmacy Records for Patients on Anti-HIV Drugs
  128. Do the research goal and databases match? A checklist for a systematic approach
  129. Risk of Extrapyramidal Syndromes with Haloperidol, Risperidone, or Olanzapine
  130. Thoracic and thoracoabdominal aortic aneurysm repair: Use of evoked potential monitoring in 118 patients
  131. Comparison of different methods to estimate prevalence of drug use by using pharmacy records
  132. Is Drug Treatment of Hypertension in Clinical Practice as Effective as in Randomized Controlled Trials with Regard to the Reduction of the Incidence of Stroke?
  133. Antihypertensive Drug Therapies and the Risk of Ischemic Stroke
  134. Drug-Induced Lipid Changes
  135. Lipid Abnormalities Induced by Novel Antipsychotic Drugs
  136. The interface between pharmacoepidemiology and pharmacogenetics
  137. Estimating the prevalence of hypertension corrected for the effect of within-person variability in blood pressure
  138. The completeness of medication histories in hospital medical records of patients admitted to general internal medicine wards
  139. Use of prevalence and incidence measures to describe age-related prescribing of antidepressants with and without anticholinergic effects
  140. Influence of question structure on the recall of self-reported drug use
  141. The relationship between evoked potentials and measurements of S-100 protein in cerebrospinal fluid during and after thoracoabdominal aortic aneurysm surgery
  142. Excess Stroke Among Hypertensive Men and Women Attributable to Undertreatment of Hypertension
  143. Within patient variability of lower extremity muscle responses to transcranial electrical stimulation with pulse trains in aortic surgery
  144. Within-Patient Variability of Myogenic Motor-Evoked Potentials to Multipulse Transcranial Electrical Stimulation During Two Levels of Partial Neuromuscular Blockade in Aortic Surgery
  145. Within-Patient Variability of Myogenic Motor-Evoked Potentials to Multipulse Transcranial Electrical Stimulation During Two Levels of Partial Neuromuscular Blockade in Aortic Surgery
  146. Sex differences in antihypertensive drug use
  147. Undertreatment of hypertension in a population-based study in The Netherlands
  148. Is placebo analgesia mediated by endogenous opioids? A systematic review
  149. Assessment of control of hypertension in the population
  150. Sex-based differences in the pharmacological treatment of hypertension
  151. Physician-Assisted Death and Pharmacy Practice in the Netherlands
  152. Reply of the authors
  153. Sex differences in the pharmacological treatment of hypertension
  154. Validation of pharmacy records in drug exposure assessment
  155. Current use of thiazide diuretics and prevention of femur fractures
  156. Drug Interactions With Thrombolytic Agents
  157. Influence of Chlorthalidone on the Pharmacokinetics and Pharmacodynamics of Org 10172 (Lomoparan®), A Low Molecular Weight Heparinoid, in Healthy Volunteers