All Stories

  1. Childhood obesity in relation to poor asthma control and exacerbation: a meta-analysis
  2. Genotype-guided coumarin dosing: where are we now and where do we need to go next?
  3. The COAG and EU-PACT Trials: What is the Clinical Benefit of Pharmacogenetic-Guided Coumarin Dosing During Therapy Initiation?
  4. Beliefs about medicines in Dutch acenocoumarol and phenprocoumon users
  5. Evaluation of the effects of single‐nucleotide polymorphisms in CYP3A4 and CYP4F2 on stable phenprocoumon and acenocoumarol maintenance doses: reply
  6. Patients Benefit From Genetics-Guided Coumarin Anticoagulant Therapy
  7. Phenotype Standardization of Angioedema in the Head and Neck Region Caused by Agents Acting on the Angiotensin System
  8. Phenotype Standardization for Statin-Induced Myotoxicity
  9. Application of routine electronic health record databases for pharmacogenetic research
  10. Pharmacogenetic analysis of GLCCI1 in three north European pediatric asthma populations with a reported use of inhaled corticosteroids
  11. Pharmacogenetic‐guided dosing of coumarin anticoagulants: algorithms for warfarin, acenocoumarol and phenprocoumon
  12. Pharmacogenomics: Advancing Evidence-Based Personalized Medicine
  13. The SLCO1B1 c.521T>C polymorphism is associated with dose decrease or switching during statin therapy in the Rotterdam Study
  14. A Randomized Trial of Genotype-Guided Dosing of Acenocoumarol and Phenprocoumon
  15. A Randomized Trial of Genotype-Guided Dosing of Warfarin
  16. ADRB2 Arg16 and the need for collaboration in childhood asthma pharmacogenomics
  17. Arg16 ADRB2 genotype increases the risk of asthma exacerbation in children with a reported use of long-acting β 2 -agonists: results of the pacman cohort
  18. Secretory Phospholipase A2-IIA and Cardiovascular Disease
  19. Robust association of the LPA locus with low-density lipoprotein cholesterol lowering response to statin treatment in a meta-analysis of 30 467 individuals from both randomized control trials and observational studies and association with coronary arte...
  20. Cholesteryl Ester Transfer Protein Polymorphisms, Statin Use, and Their Impact on Cholesterol Levels and Cardiovascular Events
  21. Clinical utility of asthma biomarkers: from bench to bedside
  22. Pharmacogenetics of statins
  23. Inflammatory phenotypes underlying uncontrolled childhood asthma despite inhaled corticosteroid treatment: rationale and design of the PACMAN2 study
  24. Cost–effectiveness of pharmacogenetic-guided dosing of phenprocoumon in atrial fibrillation
  25. Evaluation of the effects of single-nucleotide polymorphisms in CYP3A4 and CYP4F2 on stable phenprocoumon and acenocoumarol maintenance doses
  26. Corrigendum to: ‘Loading and maintenance dose algorithms for phenprocoumon and acenocoumarol using patient characteristics and pharmacogenetic data’ [Eur Heart J (2011) 32 (15): 1909-1917, doi:10.1093/eurheartj/ehr116]
  27. Pharmacogenetics of ACE inhibitor-induced angioedema and cough: a systematic review and meta-analysis
  28. Pharmacogenetics and Individualized Therapy. Edited by Anke‐Hilse Maitland‐van der Zee and Ann K. Daly
  29. Evaluation of the effect of genetic variations inGATA-4on the phenprocoumon and acenocoumarol maintenance dose
  30. Long‐term anticoagulant effects of CYP2C9 and VKORC1 genotypes in phenprocoumon users
  31. The effect of omeprazole and esomeprazole on the maintenance dose of phenprocoumon
  32. Evaluation of the effect of statin use on the acenocoumarol and phenprocoumon maintenance dose
  33. Cost–effectiveness of pharmacogenetics in anticoagulation: international differences in healthcare systems and costs
  34. Vascular Endothelial Growth Factor Pathway Polymorphisms as Prognostic and Pharmacogenetic Factors in Cancer: A Systematic Review and Meta-analysis
  35. Validation of the acenocoumarol EU-PACT algorithms: similar performance in the Rotterdam Study cohort as in the original study
  36. Exhaled NO is a poor marker of asthma control in children with a reported use of asthma medication: a pharmacy‐based study
  37. Conference Scene: 5th Anniversary Meeting of the European Research Network Pharmacogenetics/Pharmacogenomics
  38. Added value of pharmacogenetic testing in predicting statin response: results from the REGRESS trial
  39. An evaluation of gene–gene interaction between the CYP2C9 and VKORC1 genotypes affecting the anticoagulant effect of phenprocoumon and acenocoumarol
  40. Pharmacogenetics and Individualized Therapy
  41. Pharmacogenetics: Possibilities and Pitfalls
  42. Cardiovascular Pharmacogenetics
  43. Pharmacogenetics of Asthma and COPD
  44. Long‐term anticoagulant effects of the CYP2C9 and VKORC1 genotypes in acenocoumarol users
  45. Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes Loci
  46. Future of Pharmacogenetics in Cardiovascular Diseases
  47. Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes Loci
  48. Variation atGLCCI1andFCER2: one step closer to personalized asthma treatment
  49. Genotyping for CYP2C9 and VKORC1 alleles by a novel point of care assay with HyBeacon® probes
  50. FCER2 T2206C variant associated with chronic symptoms and exacerbations in steroid-treated asthmatic children
  51. Implementation of pharmacogenetics in clinical practice is challenging
  52. Inhaled corticosteroid adherence in paediatric patients: the PACMAN cohort study
  53. Asthma Symptoms in Pediatric Patients: Differences throughout the Seasons
  54. Genetic variability within the cholesterol lowering pathway and the effectiveness of statins in reducing the risk of MI
  55. Limited agreement between current and long‐term asthma control in children: the PACMAN cohort study
  56. Loading and maintenance dose algorithms for phenprocoumon and acenocoumarol using patient characteristics and pharmacogenetic data
  57. Biomarkers of therapy responsiveness in asthma: pitfalls and promises
  58. Pharmacogenetics: From Bench to Byte— An Update of Guidelines
  59. Uncontrolled asthma at age 8: The importance of parental perception towards medication
  60. Asthma medication use in infancy: determinants related to prescription of drug therapy
  61. From evidence based medicine to mechanism based medicine. Reviewing the role of pharmacogenetics
  62. CYP2C19 and ABCB1 genes and individualized treatment with clopidogrel
  63. Practical recommendations for pharmacogenomics-based prescription: 2010 ESF–UB Conference on Pharmacogenetics and Pharmacogenomics
  64. Genetic variation in the renin—angiotensin system, use of renin—angiotensin system inhibitors and the risk of myocardial infarction
  65. Variants of ADAMTS1 modify the effectiveness of statins in reducing the risk of myocardial infarction
  66. From evidence based medicine to mechanism based medicine. Reviewing the role of pharmacogenetics
  67. High agreement between parental reported inhaled corticosteroid use and pharmacy prescription data
  68. SNP s: Single Nucleotide Polymorphisms and Pharmacogenomics: Individually Designed Drug Therapy
  69. Pharmacogenetics of Anti-Inflammatory Therapy in Asthma: Corticosteroids and Leukotriene Antagonists
  70. Pharmacogenetic interactions betweenABCB1andSLCO1B1tagging SNPs and the effectiveness of statins in the prevention of myocardial infarction
  71. Clinical and economic consequences of pharmacogenetic-guided dosing of warfarin
  72. Statin Prescribing in the Elderly in the Netherlands
  73. A systematic review of cost–effectiveness analyses of pharmacogenetic-guided dosing in treatment with coumarin derivatives
  74. Patterns of asthma medication use: early asthma therapy initiation and asthma outcomes at age 8†
  75. Single nucleotide polymorphisms in genes that are associated with a modified response to statin therapy: the Rotterdam Study
  76. Asthma Therapy During the First 8 Years of Life: A PIAMA Cohort Study
  77. Methodological and statistical issues in pharmacogenomics
  78. Pharmacogenetics and pharmacogenomics: practical applications in routine medical practice
  79. Pharmacogenetics and the Pharmaceutical Industry
  80. Genotype-guided dosing of coumarin derivatives: the European pharmacogenetics of anticoagulant therapy (EU-PACT) trial design
  81. Determinants of DNA yield and purity collected with buccal cell samples
  82. Conference Scene: Pharmacogenomics at the second PharmSciFair 2009: adverse drug reactions and clinical implementation
  83. Systematic Review of Pharmacogenetic Warfarin Dosing
  84. Genetic determinants of response to statins
  85. Pharmacogenetics of anti-inflammatory treatment in children with asthma: rationale and design of the PACMAN cohort
  86. Conference Scene: Initiatives on future biobanking in pharmacogenomics
  87. Clinical impact of adducin polymorphism
  88. Systems biology in pharmacogenomic research: the way to personalized prescribing?
  89. Reasons for non‐response in observational pharmacogenetic research
  90. The effect of nine common polymorphisms in coagulation factor genes (F2, F5, F7, F12 and F13) on the effectiveness of statins: the GenHAT study
  91. AAPS–FIP Summary Workshop Report: Pharmacogenetics in Individualized Medicine: Methods, Regulatory, and Clinical Applications
  92. Pharmacogenomic insights into treatment and management of statin-induced myopathy
  93. Interaction between the Gly460Trp α-adducin gene variant and diuretics on the risk of myocardial infarction
  94. Recruitment of participants through community pharmacies for a pharmacogenetic study of antihypertensive drug treatment
  95. Pharmacogenomic importance of pravastatin
  96. Interactions between the single nucleotide polymorphisms in the homocysteine pathway (MTHFR 677C>T, MTHFR 1298 A>C, and CBSins) and the efficacy of HMG-CoA reductase inhibitors in preventing cardiovascular disease in high-risk patients of hyperte...
  97. Pharmacogenomics of coumarin anticoagulants: Are we underestimating the role of CYP2C9?
  98. Effectiveness of statins in the reduction of the risk of myocardial infarction is modified by the GNB3 C825T variant
  99. Are there interactions between the Gly460Trp α-adducin gene variant and the use of diuretics?
  100. Workshop outcomes report: Initiatives to establish a European Network of pharmacogenetics/genomics and progress
  101. Epistatic Effect of Cholesteryl Ester Transfer Protein and Hepatic Lipase on Serum High-Density Lipoprotein Cholesterol Levels
  102. The cholesteryl ester transfer protein I405V polymorphism is associated with increased high-density lipoprotein levels and decreased risk of myocardial infarction: the Rotterdam Study
  103. Absence of an interaction between the angiotensin-converting enzyme insertion-deletion polymorphism and pravastatin on cardiovascular disease in high-risk hypertensive patients: The Genetics of Hypertension-Associated Treatment (GenHAT) study
  104. Apoliprotein-E polymorphism and response to pravastatin in men with coronary artery disease (REGRESS)
  105. Wat is de relevantie van de interactie tussen verapamil en simvastatine?
  106. A multilocus approach to the antihypertensive pharmacogenetics of hydrochlorothiazide
  107. Pharmacogenetics of response to statins: Where do we stand?
  108. Genetic Polymorphisms and Response to HMG-CoA Reductase Inhibitors
  109. Pharmacogenetics in health-care practice
  110. Comparison of two methodologies to analyze exposure to statins in an observational study on effectiveness
  111. Pharmacoeconomic evaluation of testing for angiotensin-converting enzyme genotype before starting ??-hydroxy-??-methylglutaryl coenzyme A reductase inhibitor therapy in men
  112. Adherence to and dosing of ??-hydroxy-??-methylglutaryl coenzyme A reductase inhibitors in the general population differs according to apolipoprotein E-genotypes
  113. 2P-0589 Influence of apolipoprotein E polymorphisms on coronary artery disease and on the efficacy of HMG-CoA reductase inhibitors in men
  114. Adherence to and dosing of statins differs according to apolipoprotein E-genotypes
  115. The effectiveness of hydroxy-methylglutaryl coenzyme A reductase inhibitors (statins) in the elderly is not influenced by apolipoprotein E genotype
  116. Genetic polymorphisms: importance for response to HMG-CoA reductase inhibitors
  117. The effectiveness of HMG‐CoA reductase inhibitors in an elderly population is independent of apolipoprotein E‐genotypes
  118. The association between antihypertensive drug therapies and plasma lipid levels in the general population
  119. Pharmacogenetics and the Role of the Pharmacist
  120. Drug-Induced Lipid Changes
  121. The interface between pharmacoepidemiology and pharmacogenetics