All Stories

  1. Necroptosis is dispensable for motor neuron degeneration in a mouse model of ALS

    Article • Cell Death and Differentiation, November 2019, Springer Science + Business Media

    Dr Andre L Samson

  2. VDAC2 enables BAX to mediate apoptosis and limit tumor development

    Article • Nature Communications, November 2018, Springer Science + Business Media

    Dr Andre L Samson, Andrew Morokoff

  3. Endogenous fibrinolysis facilitates clot retraction in vivo

    Article • Blood, October 2017, American Society of Hematology

    Dr Andre L Samson

  4. Protein aggregation or liberation during cell necrosis

    Article • Open Biology, November 2016, Royal Society Publishing

    Dr Andre L Samson, Professor Robert L Medcalf

  5. Passenger mutations and aberrant gene expression in congenic tissue plasminogen activator-deficient mouse strains

    Article • Journal of Thrombosis and Haemostasis, June 2016, Wiley

    Dr Andre L Samson

  6. MouseMove: an open source program for semi-automated analysis of movement and cognitive testing in rodents

    Article • Scientific Reports, November 2015, Nature

    Dr Andre L Samson

  7. Dendritic Cell-Mediated Phagocytosis but Not Immune Activation Is Enhanced by Plasmin

    Article • PLoS ONE, July 2015, PLOS

    Dr Andre L Samson

  8. Activated platelets rescue apoptotic cells via paracrine activation of EGFR and DNA-dependent protein kinase

    Article • Cell Death and Disease, September 2014, Nature

    Dr Andre L Samson

  9. Oxidation of an Exposed Methionine Instigates the Aggregation of Glyceraldehyde-3-phosphate Dehydrogenase

    Article • Journal of Biological Chemistry, August 2014, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Andre L Samson

  10. Tissue-type plasminogen activator is an extracellular mediator of Purkinje cell damage and altered gait

    Article • Experimental Neurology, November 2013, Elsevier

    Dr Andre L Samson

  11. Nucleocytoplasmic Coagulation: An Injury-Induced Aggregation Event that Disulfide Crosslinks Proteins and Facilitates Their Removal by Plasmin

    Article • Cell Reports, October 2012, Elsevier

    Dr Andre L Samson

  12. The tissue-type plasminogen activator-plasminogen activator inhibitor 1 complex promotes neurovascular injury in brain trauma: evidence from mice and humans

    Article • Brain, July 2012, Oxford University Press (OUP)

    Dr Andre L Samson

  13. Neovascularization Is Attenuated With Aldosterone Synthase Inhibition in Rats With Retinopathy

    Article • Hypertension, January 2012, Wolters Kluwer Health

    Dr Andre L Samson

  14. Compartment- and context-specific changes in tissue-type plasminogen activator (tPA) activity following brain injury and pharmacological stimulation

    Article • Laboratory Investigation, April 2011, Nature

    Dr Andre L Samson

  15. Thrombin-induced activation of astrocytes in mixed rat hippocampal cultures is inhibited by soluble thrombomodulin

    Article • Brain Research, March 2011, Elsevier

    Dr Andre L Samson

  16. Novel Role of Platelets in Mediating Inflammatory Responses and Ventricular Rupture or Remodeling Following Myocardial Infarction

    Article • Arteriosclerosis Thrombosis and Vascular Biology, January 2011, Wolters Kluwer Health

    Dr Andre L Samson

  17. A nonfibrin macromolecular cofactor for tPA-mediated plasmin generation following cellular injury

    Article • Blood, July 2009, American Society of Hematology

    Dr Andre L Samson

  18. Low molecular weight contaminants in commercial preparations of plasmin and t-PA activate neurons

    Article • Journal of Thrombosis and Haemostasis, December 2008, Wiley

    Dr Andre L Samson

  19. Tissue-type plasminogen activator requires a co-receptor to enhance NMDA receptor function

    Article • Journal of Neurochemistry, October 2008, Wiley

    Dr Andre L Samson

  20. Two conserved regions within the tissue-type plasminogen activator gene promoter mediate regulation by brain-derived neurotrophic factor

    Article • FEBS Journal, April 2007, Wiley

    Dr Andre L Samson

  21. Oncostatin M is a neuroprotective cytokine that inhibits excitotoxic injury in vitro and in vivo

    Article • The FASEB Journal, November 2006, Federation of American Societies For Experimental Biology (FASEB)

    Dr Andre L Samson

  22. Tissue-Type Plasminogen Activator: A Multifaceted Modulator of Neurotransmission and Synaptic Plasticity

    Article • Neuron, June 2006, Elsevier

    Professor Robert L Medcalf, Dr Andre L Samson

  23. Vampire Bat Salivary Plasminogen Activator (Desmoteplase): A Unique Fibrinolytic Enzyme That Does Not Promote Neurodegeneration

    Article • Stroke, January 2003, Wolters Kluwer Health

    Dr Andre L Samson