All Stories

  1. Cephalostatins and ritterazines: Distinctive dimeric marine-derived steroidal pyrazine alkaloids with intriguing anticancer activities

    Article • Bioorganic Chemistry, October 2024, Elsevier

    Dr Amr El-Demerdash

  2. Investigating the Structure-Activity Relationship of Laulimalides Marine Macrolides as Promising Inhibitors for SARS-CoV-2 Main Protease (Mpro)

    Article • Journal of Computational Biophysics and Chemistry, September 2024, World Scientific Pub Co Pte Lt

    Dr Amr El-Demerdash

  3. Unlocking saponin biosynthesis in soapwort

    Article • Nature Chemical Biology, July 2024, Springer Science + Business Media

    Dr Amr El-Demerdash

  4. Employing acetoacetamide as a key synthon for synthesizing novel thiophene derivatives and assessing their potential as antioxidants and antimicrobial agents

    Article • Journal of Heterocyclic Chemistry, May 2024, Wiley

    Dr Amr El-Demerdash

  5. Complete biosynthesis of QS-21 in engineered yeast

    Article • Nature, May 2024, Springer Science + Business Media

    Dr Amr El-Demerdash

  6. Synthesis and molecular docking of some new thiazolidinone and thiadiazole derivatives as anticancer agents

    Article • Chemistry & Biodiversity, March 2024, Wiley

    Dr Amr El-Demerdash

  7. SYNTHESIS OF SOME NOVEL THIOPHENE ANALOGUES AS POTENTIAL ANTICANCER AGENTS

    Article • Chemistry & Biodiversity, March 2024, Wiley

    Dr Amr El-Demerdash

  8. Agro-byproduct valorization of radish and turnip leaves and roots as new sources of antibacterial and antivirulence agents through metabolomics and molecular networking

    Article • Scientia Horticulturae, March 2024, Elsevier

    Dr Amr El-Demerdash

  9. Anthocyanins - dietary natural products with a variety of bioactivities for the promotion of human and animal health

    Article • Animal Science Papers and Reports, March 2024, De Gruyter

    Dr Amr El-Demerdash

  10. Complete biosynthesis of the potent vaccine adjuvant QS-21

    Article • Nature Chemical Biology, January 2024, Springer Science + Business Media

    Dr Amr El-Demerdash

  11. Unveiling the Potential of Marine-Derived Diterpenes from the order Alcyonacea as Promising Anti-obesity Agents

    Article • Current Research in Biotechnology, January 2024, Elsevier

    Dr Amr El-Demerdash

  12. Discovery of isoflavone phytoalexins in wheat reveals an alternative route to isoflavonoid biosynthesis

    Article • Nature Communications, November 2023, Springer Science + Business Media

    Dr Amr El-Demerdash

  13. Dietary factors in nonalcoholic fatty liver disease: impacts on human and animal health - a review

    Article • Animal Science Papers and Reports, September 2023, De Gruyter

    Dr Amr El-Demerdash

  14. Investigating the antiviral therapeutic potentialities of marine polycyclic lamellarin pyrrole alkaloids as promising inhibitors for SARS-CoV-2 and Zika main proteases (Mpro)

    Article • Journal of Biomolecular Structure and Dynamics, May 2023, Taylor & Francis

    Dr Amr El-Demerdash

  15. Signal crosstalk of phytomelatonin during salinity stress tolerance in plants

    Article • Plant Growth Regulation, May 2023, Springer Science + Business Media

    Dr Amr El-Demerdash

  16. Investigating the Structure-Activity Relationship of Laulimalides Marine Macrolides as Promising Inhibitors for SARS-CoV-2 Main Protease (Mpro)

    Article • May 2023, American Chemical Society (ACS)

    Dr Amr El-Demerdash

  17. Elucidation of the pathway for biosynthesis of saponin adjuvants from the soapbark tree

    Article • Science, March 2023, American Association for the Advancement of Science

    Dr Amr El-Demerdash

  18. Recent Advances in Discovery, Biosynthesis and Therapeutic Potentialities of Isocoumarins Derived from Fungi: A Comprehensive Update

    Article • February 2023, American Chemical Society (ACS)

    Dr Amr El-Demerdash

  19. The International Natural Product Sciences Taskforce (INPST) and the power of Twitter networking exemplified through #INPST hashtag analysis

    Article • Phytomedicine, January 2023, Elsevier

    Dr Amr El-Demerdash, Professor George Perry, Prof. Antoni Sureda, Dr Smith B. Babiaka, Humboldt Fellow, Prof. Tomasz M. Karpiński

  20. Recent advances in the discovery, biosynthesis, and therapeutic potential of isocoumarins derived from fungi: a comprehensive update

    Article • RSC Advances, January 2023, Royal Society of Chemistry

    Dr Amr El-Demerdash

  21. Investigating the hepatoprotective potentiality of marine-derived steroids as promising inhibitors of liver fibrosis

    Article • RSC Advances, January 2023, Royal Society of Chemistry

    Dr Amr El-Demerdash

  22. Pederins, mycalamides, onnamides and theopederins: Distinctive polyketide families with intriguing therapeutic potentialities

    Article • Current Research in Biotechnology, January 2023, Elsevier

    Dr Amr El-Demerdash

  23. Investigating the Antiviral Therapeutic Potentialities of Marine Polycyclic Lamellarin Pyrrole Alkaloids as Promising Inhibitors for SARS-CoV-2 and Zika Main Proteases (Mpro)

    Article • October 2022, American Chemical Society (ACS)

    Dr Amr El-Demerdash

  24. Chemical Diversity, Biological Activities and Biosynthesis of Fungal Naphthoquinones and Their Derivatives: A Comprehensive Update

    Article • Journal of Molecular Structure, July 2022, Elsevier

    Dr Amr El-Demerdash

  25. Investigating the structure-activity relationship of marine polycyclic batzelladine alkaloids as promising inhibitors for SARS-CoV-2 main protease (Mpro)

    Article • Computers in Biology and Medicine, June 2022, Elsevier

    Dr Amr El-Demerdash

  26. Chemical Diversity and Biological Activities of Anthraquinones Derived from Marine Fungi: A Comprehensive Update

    Article • March 2022, American Chemical Society (ACS)

    Dr Amr El-Demerdash

  27. Investigating the Structure-Activity Relationship of Marine Polycyclic Batzelladine Alkaloids as Promising Inhibitors for SARS-CoV-2 Main Protease (Mpro)

    Article • March 2022, American Chemical Society (ACS)

    Dr Amr El-Demerdash

  28. Chemical diversity, medicinal potentialities, biosynthesis, and pharmacokinetics of anthraquinones and their congeners derived from marine fungi: a comprehensive update

    Article • RSC Advances, January 2022, Royal Society of Chemistry

    Dr Amr El-Demerdash

  29. Marine Brominated Tyrosine Alkaloids as Promising Inhibitors of SARS-CoV-2

    Article • Molecules, October 2021, MDPI AG

    Dr Amr El-Demerdash

  30. Punica granatum L var nana: A Hepatoprotective and Curative Agent Against CCl4 Induced Hepatotoxicity in Rats

    Article • Egyptian Journal of Chemistry, October 2021, Egypts Presidential Specialized Council for Education and Scientific Research

    Dr Amr El-Demerdash

  31. A unique view of SARS-CoV-2 through the lens of ORF8 protein

    Article • Computers in Biology and Medicine, June 2021, Elsevier

    Dr Amr El-Demerdash, Ángel Serrano Aroca

  32. Comprehensive Virtual Screening of the Antiviral Potentialities of Marine Polycyclic Guanidine Alkaloids against SARS-CoV-2 (COVID-19)

    Article • Biomolecules, March 2021, MDPI AG

    Dr Amr El-Demerdash

  33. Bioactive Bromotyrosine Derivatives from the Pacific Marine Sponge Suberea clavata (Pulitzer-Finali, 1982)

    Article • Marine Drugs, March 2021, MDPI AG

    Dr Amr El-Demerdash

  34. Cytotoxic constituents from the wheat plant pathogen Parastagonospora nodorum SN15

    Article • Natural Product Research, February 2021, Taylor & Francis

    Dr Amr El-Demerdash, Pr Alexandre E Escargueil

  35. Investigating the structure–activity relationship of marine natural polyketides as promising SARS-CoV-2 main protease inhibitors

    Article • RSC Advances, January 2021, Royal Society of Chemistry

    Dr Amr El-Demerdash

  36. Comprehensive Virtual Screening of the Antiviral Potentialities of Marine Polycyclic Guanidine Alkaloids against SARS-CoV-2 (Covid-19)

    Article • December 2020, American Chemical Society (ACS)

    Dr Amr El-Demerdash

  37. Comprehensive Virtual Screening of the Antiviral Potentialities of Marine Polycyclic Guanidine Alkaloids against SARS-CoV-2 (Covid-19)

    Article • December 2020, American Chemical Society (ACS)

    Dr Amr El-Demerdash

  38. A new triterpene saponin from Fagonia schimperi

    Article • Journal of Applied Pharmaceutical Science, December 2020, Journal of Applied Pharmaceutical Science

    Dr Amr El-Demerdash

  39. Insights about clinically approved and Preclinically investigated marine natural products

    Article • Current Research in Biotechnology, November 2020, Elsevier

    Dr Amr El-Demerdash, Mosad Ghareeb

  40. Crambescidin Acid from the French Polynesian Monanchora n. sp. Marine Sponge

    Article • Chemistry of Natural Compounds, November 2020, Springer Science + Business Media

    Dr Amr El-Demerdash

  41. A Review: Synthesis and Medicinal Importance of Coumarins and their Analogues (Part II)

    Article • Current Bioactive Compounds, October 2020, Bentham Science Publishers

    Dr Amr El-Demerdash, Professor Moustafa A. Gouda, Dr. Belal H.M Hussein, Mohamed Ibrahim , wafaa hamama

  42. Short-Cut Bio-Inspired Synthesis of Tricyclic Guanidinic Motifs of Crambescidins and Batzelladines Marine Alkaloids

    Article • European Journal of Organic Chemistry, June 2020, Wiley

    Dr Amr El-Demerdash

  43. Chemical Diversity and Biological Activities of Meroterpenoids from Marine Derived-Fungi: A Comprehensive Update

    Article • Marine Drugs, June 2020, MDPI AG

    Dr Amr El-Demerdash

  44. Synthesis and biological evaluation of some heterocyclic scaffolds based on the multifunctional N ‐(4‐acetylphenyl)‐2‐chloroacetamide

    Article • Journal of Heterocyclic Chemistry, May 2020, Wiley

    Dr Amr El-Demerdash

  45. Utilization of 5‐Chloro‐2‐(cyanoacetamido)pyridines in the Synthesis of Biologically Active Heterocyclic Hybrids

    Article • ChemistrySelect, February 2020, Wiley

    Dr Amr El-Demerdash

  46. Highly oxygenated isoprenylated cyclohexanoids from the fungus Parastagonospora nodorum SN15

    Article • Phytochemistry, October 2019, Elsevier

    Dr Amr El-Demerdash

  47. Chemical Diversity and Biological Activities of Marine Sponges of the Genus Suberea: A Systematic Review

    Article • Marine Drugs, February 2019, MDPI AG

    Dr Amr El-Demerdash

  48. Chemical Diversity and Biological Activities of Phaeosphaeria Fungi Genus: A Systematic Review

    Article • Journal of Fungi, December 2018, MDPI AG

    Dr Amr El-Demerdash

  49. Fatty Acids Pattern from the French Polynesian Monanchora n. sp. Marine Sponge

    Article • Chemistry of Natural Compounds, November 2018, Springer Science + Business Media

    Dr Amr El-Demerdash

  50. Phytol: A review of biomedical activities

    Article • Food and Chemical Toxicology, November 2018, Elsevier

    Dr Amr El-Demerdash, Prof. Maciej Banach, Dr. Utpal Kumar Karmakar

  51. Chemistry and Biological Activities of the Marine Sponges of the Genera Mycale (Arenochalina), Biemna and Clathria

    Article • Marine Drugs, June 2018, MDPI AG

    Dr Atanas G. Atanasov, Dr Amr El-Demerdash

  52. Bioactive Bromotyrosine-Derived Alkaloids from the Polynesian Sponge Suberea ianthelliformis

    Article • Marine Drugs, April 2018, MDPI AG

    Dr Amr El-Demerdash

  53. Batzella, Crambe and Monanchora: Highly Prolific Marine Sponge Genera Yielding Compounds with Potential Applications for Cancer and Other Therapeutic Areas

    Article • Nutrients, January 2018, MDPI AG

    Dr Amr El-Demerdash

  54. Molecular Responses of Cancers by Natural Products: Modifications of Autophagy Revealed by Literature Analysis

    Article • Critical Reviews™ in Oncogenesis, January 2018, Begell House

    Dr Amr El-Demerdash

  55. Unguiculins A-C: cytotoxic bis-guanidine alkaloids from the French Polynesian sponge, Monanchora n. sp

    Article • Natural Product Research, October 2017, Taylor & Francis

    Dr Amr El-Demerdash

  56. Cytotoxic Guanidine Alkaloids from a French Polynesian Monanchora n. sp. Sponge

    Article • Journal of Natural Products, July 2016, American Chemical Society (ACS)

    Dr Amr El-Demerdash

  57. Gingerdione from the rhizomes of Curcuma longa

    Article • Chemistry of Natural Compounds, September 2012, Springer Science + Business Media

    Dr Amr El-Demerdash