ANTIBACTERIAL ACTIVITY AND IDENTIFICATION OF PRODUCED REUTERIN FROM LOCAL ISOLATE

What is it about?

Chemically, reuterin is identified as β-hydroxypropionaldehyde or 3-hydroxypropanal (3-HPA) and it is formed during the anaerobic condition growth of L. reuteri by the work of glycerol dehydratase which catalyzes the diversion of glycerol into reuterin compound. This bacterium uses the phoshoketolase pathway for fermentation of carbohydrates to lactate, acetic acid, ethanol, and carbon dioxide. 3-hydroxypropanal (3-HPA) is produced as an intermediate step in the conversion of glycerol to 1,3-propanediol, a pathway proposed to regenerate NAD+ from NADH and to contribute to improved growth yield (Rodriguez et al., 2003). Many studies were explained to the technique of activity by which the reuterin compound spends its antimicrobial impacts has been so hard to be known. The cause is the aldehyde group of the reuterin, which is highly reactive; thus, the reuterin compound can be converted to different compounds in the hydrous solutions.

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Why is it important?

In recent years, many biologists have shown a wide interest in studying antibiotics produced by Lactobacilli. This interesting was due to many reasons such as their wide inhibition spectrum for growth of pathogens and food damaging bacteria. In addition, Lactobacilli antibiotics represent a natural inhibitor used in food preservation

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