Hydration Helps Thyroid Cancer Patients Leave Hospital Sooner After Radioiodine Therapy

What is it about?

In thyroid cancer treatment, radioiodine (131I) is commonly used for thyroid ablation within an activity range of 1110-11100 MBq (30-300 mCi). This study evaluated the dose rates of 303 patients post-therapy and the effects of hydration on those near the discharge dose limit. Patients with dose rates of 30-40 µSv/h after initial measurements were asked to drink 1.5-2 liters of water over 4-6 hours, which helped reduce their dose rates, allowing earlier discharge. Around 72% of patients treated with 3700 MBq (100 mCi) and 5550 MBq (150 mCi) were discharged early after hydration. The study highlights the importance of monitoring radiation doses to predict isolation times and optimize patient discharge protocols.

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Photo by engin akyurt on Unsplash

Photo by engin akyurt on Unsplash

Why is it important?

This research is crucial because it addresses the optimization of radioiodine therapy for thyroid cancer patients, specifically focusing on the safe and efficient discharge of patients after treatment. By evaluating the impact of hydration on reducing radiation dose rates, the study offers a pragmatic solution to expedite patient release, thereby improving hospital workflow, reducing healthcare costs, and minimizing the inconvenience for patients. Additionally, adhering to safety regulations ensures that both patients and healthcare workers are protected from excessive radiation exposure. Key Takeaways: 1. Hydration and Dose Rate Reduction: The study found that approximately 72% of thyroid cancer patients treated with 3700 MBq (100 mCi) and 5550 MBq (150 mCi) of radioiodine had their dose rate reduced to below the discharge threshold by drinking 1.5-2 liters of water within 4-6 hours post-treatment. 2. Impact on Discharge Timing: The research indicates that frequent dose rate measurements and encouraging hydration can significantly shorten the isolation period for patients, with 58% of patients being discharged within 24 hours and an additional 14.6% within the next 24 hours. 3. Regulatory Compliance: This study underscores the importance of adhering to radiation safety regulations, such as those set by the Turkish Radiation Safety Regulation and the European Union, to ensure safe discharge practices and protect against radiation exposure.