What is it about?
This paper narrates the development and validation of stability indicating method for the determination of assay of Ethanol in clobetasol propionate foam, 0.05% using a thermal gradient GC method with FID detection.
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Why is it important?
Monitor of Ethanol content in pharmaceutical aerosol products is very important during manufacturing and stability process because aerosol rate, droplet shape and particle size are closely linked to the formulation vapor pressure, which is regulated by the ethanol concentration. To address this challenge, a simple, accurate and quantitative analysis method for the determination of Ethanol content is needed as the standard method of quality control for aerosol manufacturers and as a guide for government related sanitary agencies.
Read the Original
This page is a summary of: A Rapid Method for the determination of Dehydrated alcohol (Ethanol) content in Clobetasol propionate foam by Non-polar Capillary Gas chromatography, Research Journal of Pharmacy and Technology, November 2021, A and V Publications,
DOI: 10.52711/0974-360x.2021.01029.
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