What is it about?
Changes in gray matter volume and white matter integrity have been previously reported in schizophrenia. However, only a few studies have interpreted these changes together. Therefore, this study aimed to investigate gray matter and white matter changes in patients with schizophrenia and their correlations with clinical symptoms.
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Why is it important?
Whole-brain analyses revealed decreased grey matter volume in the bilateral insulae and alterations in the white matter tracts intersecting with the subinsular white matter, suggesting that the insula may be the main brain region affected in schizophrenia.
Perspectives
We would like to thank all participants for making this study possible.
Cigdem Ulasoglu-Yildiz
Department of Neuroscience, Aziz Sancar Institute of Experimental Medicine, Istanbul University
Read the Original
This page is a summary of: A combined VBM and DTI study of schizophrenia: bilateral decreased insula volume and cerebral white matter disintegrity corresponding to subinsular white matter projections unlinked to clinical symptomatology, Diagnostic and Interventional Radiology, September 2017, Journal of Clinical Research of Pediatric Endocrinology,
DOI: 10.5152/dir.2017.16519.
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