What is it about?
The present study deals with harmful effects of aluminum fluoride on liver functions of albino rats viz. SGPT, SGOT, ALP, total protein, albumin, and globulin and their amelioration by vitamin C. The selected thirty-five albino rats of almost equal size and weight (120 ± 25gm) and eight weeks old were separated, they were of seven groups, five rats each. One group of albino rats was treated as a control group while aluminum fluoride was given to the next three groups of albino rats.
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Why is it important?
The other three groups of albino rats were first treated with aluminum fluoride in the same way and then given a vitamin C dose. The results demonstrated that excessive fluoride ingestion significantly decreased liver function which could be due to the toxic effect of aluminum fluoride.
Perspectives
Fluoride-induced liver dysfunction was mediated by an increase of oxidative stress affecting the internal milieu in rats. Fluoride had significant adverse effects on serum indexes in albino rats.
JSTR Journal of Science and Technological Researches
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This page is a summary of: Effect of Aluminium Fluoride on Liver Functions of Rattus Norvegicus After Amelioration by Vitamin C, Journal of Science and Technological Researches, June 2021, Journal of Science and Technological Researches,
DOI: 10.51514/jstr.3.2.2021.31-35.
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