Homologous and Heterologous Adaptation and Thermochemical Inactivation of Staphylococcus aureus with Exposure to Cinnamaldehyde

What is it about?

Can S. aureus strains become more resistant after being subjected to sublethal concentrations of the antimicrobial cinnamaldehyde (CND)? Can they also adapt to more acidic pHs? Our results show a positive effect of adaptation to CND and acid pH on the resistance of S. aureus. However, in the absence of adaptation, the presence of CND in S. aureus cultures maintained at 37 ° C, associated with increased exposure time showed an efficient bactericidal effect. Our results call attention to the conscious use of CNB as an antimicrobial agent and presents the possibility of using CNB, associated with the temperature of 37 ºC and the exposure time of 35 min, as a promising measure for the elimination of pathogenic strains of S aureus.

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