What is it about?

This research paper is about using a plant extract from Melastoma candidum to identify potential targets for antibacterial treatment. The researchers identified five differentially expressed bacterial proteins that could be targeted by the extract, and found three of them (glutamate decarboxylase, elongation factor-Tu and α-hemolysin) particularly noteworthy as they represent promising targets for future development of target-specific antibacterial agents. Additionally, minimum inhibitory concentrations values were determined which can help optimize dosage levels required to achieve effective inhibition against bacteria growth.

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Why is it important?

This research paper has identified three potential targets for developing new antibacterial agents - glutamate decarboxylase, elongation factor-Tu and α-hemolysin - using a plant extract from Melastoma candidum. These targets could potentially lead to the development of target-specific antibacterial treatments in future, providing a practical implication of this research.

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This page is a summary of: Proteomic Analysis of Bacterial Expression Profiles Following Exposure to Organic Solvent Flower Extract of <i>Melastoma candidu</i>m D Don (Melastomataceae), Tropical Journal of Pharmaceutical Research, September 2014, African Journals Online (AJOL),
DOI: 10.4314/tjpr.v13i7.11.
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