What is it about?

Peripheral arterial disease (PAD) is common disease and associated with significant morbidity and mortality. PAD is caused due to fatty deposition on artery walls that leads to narrowing of the arteries and blockage in the main blood vessels of the lower limb, which may results in discomfort or pain in the legs during walk, as well as poor quality life and an increased risk of death because of heart and cerebrovascular diseases [1-6]. Risk factors for PAD are shown in Figure 1. The main aim of this review is to focus on the status and progress of screening for peripheral arterial disease.

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Why is it important?

Mortality and limb loss is greater in chronic asymptomatic PAD, guidelines suggest that we should treat an asymptomatic ABI 0.7 aggressively with smoking cessation, drugs, and lifestyle intervention.

Perspectives

Several methods [flow-mediated vasodilatation (FMD); antero-posterior abdominal aorta diameter (APAO); intima-media thickness of the common carotid artery (CCA-IMT); arterial stiffness; trying to assess their function, but have many limitations general characteristics of the population, and should be used according to gender and age . Available evidence shows that PAD is common in patients with multiple cardiovascular risk factors and is associated with significant morbidity and mortality, but at the moment do not get benefits of your routine screening. Mortality and limb loss is greater in chronic asymptomatic PAD, guidelines suggest that we should treat an asymptomatic ABI 0.7 aggressively with smoking cessation, drugs, and lifestyle intervention.

Professor Paulo Eduardo Ocke Reis
Universidade Federal Fluminense

Read the Original

This page is a summary of: Screening for Peripheral Arterial Disease: An Update, Journal of Vascular Medicine & Surgery, January 2015, OMICS Publishing Group,
DOI: 10.4172/2329-6925.1000197.
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