Biofield Energy Treatment: A Potential Strategy for Modulating Physical, Thermal and Spectral Properties of 3-Chloro-4-fluoroaniline

What is it about?

3-Chloro-4-fluoroaniline (CFA) is used as an intermediate for the synthesis of pharmaceutical compounds. The objective of this study was to investigate the influence of biofield energy treatment on the physical, thermal and spectral properties of CFA. The study was performed in two groups (control and treated). The control group remained as untreated, and the treated group received Mr. Trivedi’s biofield energy treatment. The control and treated CFA samples were further characterized by x-ray diffraction (XRD), differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), fourier transform infrared (FT-IR) spectroscopy, and ultra violet-visible spectroscopy (UV-vis) analysis. The XRD analysis of treated CFA showed significant changes in the intensity of peaks as compared to the control. However, the average crystallite size (G) was significantly decreased by 22.08% in the treated CFA with respect to the control. The DSC analysis showed slight decrease in the melting temperature of treated CFA (47.56°C) as compared to the control (48.05°C). However, the latent heat of fusion in the treated sample was considerably changed by 4.28% with respect to the control. TGA analysis showed increase in maximum thermal decomposition temperature (Tmax) of the treated sample (163.34°C) as compared to the control sample (159.97°C). Moreover the onset temperature of treated CFA (148 °C) was also increased as compared to the control sample (140°C). Additionally, the weight loss of the treated sample was reduced (42.22%) with respect to the control (56.04%) that may be associated with increase in thermal stability. The FT-IR spectroscopic evaluation showed emergence of one new peak at 3639 cm-1 and alteration of the N-H (stretching and bending) peak in the treated sample as compared to the control. Overall, the result demonstrated that Mr. Trivedi’s biofield energy treatment has paramount influence on the physical, thermal and spectral properties of CFA.

Featured Image

Why is it important?

The amine derivatives are used as the building units in the construction of channel type supramolecular structure revealing its catalytic and separation properties due to their ability to generate intermolecular interactions [1,2]. 3-Chloro-4-fluoroaniline (CFA) is an amine derivative which is used as intermediate compound for the synthesis of herbicides [3]. Moreover, CFA is used as an intermediate for the synthesis of ciprofloxacin hydrochloride which is approved for the treatment of bone, joint infections, diarrhea, lower respiratory tract infections, and urinary tract infections [4]. Further, CFA is also used for the synthesis of norfloxacin that is the first representative of fluorinated quinolone derivatives. Norfloxacin drug has wide antimicrobial actions, and it was approved for the treatment of respiratory tract, ear, throat, nose and other infective and inflammatory diseases [5]. The chemical and physical stability of the pharmaceutical compounds are more desired quality attributes that directly affect its safety, efficacy, and shelf life [6]. Hence, it is required to explore some new alternate approach that could alter the physical and thermal properties of the compounds. Recently, biofield energy treatment has substantially changed the physical and thermal properties of metals [7,8], ceramics [9], organic product [10] and spectral properties of various pharmaceutical drugs [11]. After considering the pharmaceutical applications of CFA as intermediate, authors wish to investigate the impact of biofield energy treatment on CFA and analyzed its physical, thermal and spectral properties. The National Center for Complementary and Alternative Medicine (NCCAM), a part of the National Institute of Health (NIH), recommends the use of Complementary and Alternative Medicine (CAM) therapies as an alternative to the healthcare sector and about 36% of Americans regularly uses some form of CAM [12]. CAM includes numerous energy-healing therapies; biofield therapy is one of the energy medicine used worldwide to improve the health. The biofield treatment is being used in healing process to reduce pain, anxiety and to promote the overall health of human being [13,14]. Recently it was discovered that electrical process occurring in the human body has a relation with the magnetic field. According to Ampere’s law, the moving charge produces the magnetic field in surrounding space. Likewise, human body emits the electromagnetic waves in the form of bio-photons, which surrounds the body, and it is commonly known as biofield. Therefore, the biofield consists of an electromagnetic field, being generated by moving electrically charged particles (ions, cell, molecule, etc.) inside the human body [15,16]. Rivera-Ruiz et al. reported that electrocardiography has been extensively used to measure the biofield energy of the human body [17]. Thus, human beings have the ability to harness the energy from the environment/Universe and can transmit into any object (living or non-living) around the Globe. The object(s) will always receive the energy and responding in a useful manner that is called biofield energy. Mr. Trivedi’s unique biofield treatment is also known as The Trivedi Effect®. Mr. It is known to transform the characteristics of various living and nonliving things. Moreover, the biofield treatment has improved the growth and production of agriculture crops [18-20] and significantly altered the phenotypic characteristics of various pathogenic microbes [21,22]. The present work was focused to study the impact of biofield treatment on physical, thermal and spectral properties of CFA and characterized by XRD, DSC, TGA, FT-IR and UV-visible spectroscopy analysis.

Perspectives