What is it about?
Until now bystander mutagenesis has been associated with radiation exposure alone. We show that even a single DSB can also generate sufficient bystander signal to cause mutagenesis in naive cells.
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Why is it important?
This research is significant because we can now explore factors other than radiation that could cause bystander effect and also improve the resolution of our analysis.
Read the Original
This page is a summary of: Use of E18 Cell Model to Quantify DNA Strand Break Associated Bystander Effect (DSB-ABE), Journal of Carcinogenesis & Mutagenesis, January 2017, OMICS Publishing Group,
DOI: 10.4172/2157-2518.1000295.
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