What is it about?

relationship of peripheral donor cell chimerism with alloimmune tolerance following kidney transplantation.

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Why is it important?

This is an strategy to induce tolergenic responses and improve allograft function and survival.

Perspectives

Using very sensitive assays, our findings demonstrate associations between the presence and quantity of microchimerism following donor bone marrow cells infusion with stable graft function in infused patients.

Dr Ghasem Solgi
Hamadan University of Medical Sciences

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This page is a summary of: Donor-derived peripheral mononuclear cell DNA is associated with stable kidney allograft function: A randomized controlled trial, Chimerism, October 2011, Taylor & Francis,
DOI: 10.4161/chim.2.4.19095.
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