What is it about?
The review discusses different types of implantable systems that have been developed and reported for various brain diseases and disorders.
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Why is it important?
Drug delivery to the brain is challenging due to the presence of blood brain barrier. Implants in the brain or at sites other then brain may improve and/or sustain the availability of the drugs in the brain, which may improve the overall efficacy of the drug.
Perspectives
Implants are drug delivery systems of choice for long term drug delivery in the body. These systems would also be useful for brain diseases that require continuous and long term therapy. Although, various reports are available on development, in vitro and in vivo animal studies on implants for drug delivery to brain, there is scarcity of clinical data. More clinical studies on implants for brain are expected to bring more implantable systems in clinical use for treatment of important brain diseases.
Deepak Kapoor
Shoolini University
Read the Original
This page is a summary of: Implantable systems for drug delivery to the brain, Therapeutic Delivery, December 2017, Future Science,
DOI: 10.4155/tde-2017-0082.
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