What is it about?
Targeting of tumor cells is essential for therapy and imaging. This overview indicates promissing protein candidates, which could serve as target. For relevant background knowledge these proteins are introduced by an overview of the main subgroups of proteins that could be targeted, considering their cellular location, function, and expected copies per cell.
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Why is it important?
Substantiated targeting of cancer via tumor cells requires a broad biological knowledge of proteins. This review provides essential background information for (bio)chemists as well as clinicians about the biology of known and unknown tumormarkers, that could be used as targets for therapy and imaging.
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This page is a summary of: Selecting Targets for Tumor Imaging: An Overview of Cancer-Associated Membrane Proteins, Biomarkers in Cancer, September 2016, SAGE Publications,
DOI: 10.4137/bic.s38542.
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