What is it about?

The ocular surface is one of the few ways that living cells can be obtained from people without surgical biopsy. We review the usefulness of obtaining cells for analysis in this way, and how it contributes to understanding and treatment of human ocular surface diseases.

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Why is it important?

Impression cytology can be done using a commercial device called EyePrim that has regulatory approval.

Perspectives

Increasingly, we understand that diseases like dry eye is heterogenous and multifactorial, so personalised medicine may be facilitated by phenotyping the ocular surface this way before starting treatment. One of the bug bears which increase health spending and increase patient inconvenience is the need to repeatedly come to the clinic to try different treatments, since different patients respond to different modalities.

Prof Louis Tong
National University of Singapore

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This page is a summary of: Update on the role of impression cytology in ocular surface disease, Taiwan Journal of Ophthalmology, January 2019, Medknow,
DOI: 10.4103/tjo.tjo_57_19.
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