What is it about?

Glioblastoma could manifest in patients in a short time who have initial normal conventional MR images. Although no pathological formations are visible on cranial MRI images, we should not forget that the doubling time of glioblastoma is extremely rapid.

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Why is it important?

A persistent headache could be a sentinel sign of glioblastoma before it becomes radiologically visible. We should not neglect to perform cranial imaging at short intervals.

Perspectives

We may consider follow‑up imaging studies at short intervals in patients with persistent headaches even if they have a normal initial radiologic image.

Professor Tayfun Hakan
University of Health Sciences, İstanbul

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This page is a summary of: Glioblastoma shortly after a normal conventional brain magnetic resonance imaging: A report of two cases and review of the literature, Asian Journal of Neurosurgery, January 2021, Medknow,
DOI: 10.4103/ajns.ajns_553_20.
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