What is it about?
The single antigen vaccination did not protect against infection by antigenically complexed S. mansoni. The cocktail vaccine apparently induced an agreeable immune response against many of the antigenic components.
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Why is it important?
Schistosomulum stage is believed to be the target of protective immunity. Over the past two decades, several investigators have demonstrated the antigenic communion between Schistosoma mansoni and Biomphalaria alexandrina.
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This page is a summary of: Trials of vaccination by lung schistosomula and Biomphalaria alexandrina vaccines against experimental Schistosoma mansoni, Parasitologists United Journal, January 2016, Medknow,
DOI: 10.4103/1687-7942.192996.
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