What is it about?
This model of autoimmune dry eye can be used to evaluate drugs that target the T cells.
Featured Image
Photo by Alexandr Gusev on Unsplash
Why is it important?
There is no satisfactory treatment in Sjogren syndrome and other autoimmune diseases that cause dry eye. Current treatment like steroids have adverse effects such as raised intraocular pressure. Cyclosporine is not as potent as corticosteroids.
Perspectives
Pharmaceutical company can use this model to evaluate new topical anti-inflammatory treatment in dry eye.
Prof Louis Tong
National University of Singapore
Read the Original
This page is a summary of: A Chronic Autoimmune Dry Eye Rat Model with Increase in Effector Memory T Cells in Eyeball Tissue, Journal of Visualized Experiments, June 2017, MyJove Corporation,
DOI: 10.3791/55592.
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