What is it about?
In this study; It was aimed to calculate the volume and cell numbers of the morphometric changes caused by streptozotocin-induced diabetes in the rat liver using stereological methods. The sterology method is used to obtain unbiased quantitative morphological data on volume, surface area and length, and the number of tissues, cells or organelles.
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Why is it important?
The total volume of the liver was calculated using the Cavalieri Principle and the number of hepatocytes was calculated with the unbiased counting frame of the dissector method. In the diabetes-related groups, the increase in liver volume and cell number was significant compared to the control group (p<0.05). As a result, streptozotocin injection and the resulting diabetes lead to an increase in liver volume and hepatocyte numbers
Perspectives
In conclusion, streptozotocin injection and the resulting diabetes lead to an increase in liver volume and hepatocyte numbers. These changes help to understand the changes that occur in the liver in patients with diabetes.
Yasin TÜLÜCE
Van Yüzüncü Yıl University
Read the Original
This page is a summary of: Farklı Dozlarda Uygulanan Streptozotosinin Sıçan Karaciğerine Etkilerinin Stereolojik Metotlarla İncelenmesi, Van Veterinary Journal, March 2024, Van Veterinary Journal,
DOI: 10.36483/vanvetj.1362601.
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